• Title/Summary/Keyword: growth phase

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ALLOY STRUCTURE AND ANODIC FILM GROWTH ON RAPIDLY SOLIDIFIED AL-SI-BASED ALLOYS

  • Kim, H.S.;Thompson, G.E.;Wood, G.C.;Wright, I.G.;Maringer, R.E.
    • Journal of Surface Science and Engineering
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    • v.17 no.2
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    • pp.29-40
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    • 1984
  • The structure of rapidly solidified Al-Si-based alloys and its relationship to subsequent anodic film growth in near neutral and acid solutions have been investigated. Solidification of the alloys proceeds via pre-dendritic nuclei, associated with rugosity of the casting surface, from which cellular-type growth, comprised of aluminium-rich material surrounded by silicon-containing material, emanates. Observation of ultramicrotomed sections of the alloys and their anodic films reveals the local oxidation of the silicon-rich phase and its incorporation into the anodic alumina film, formed in near neutral solutions. Such incorporation occurs but resultant isolation of the silicon-rich phase is not possible for anodizing in phosphoric acid, and a three-dimensional network of the oxidized silicon-containing phase, with continuing development of porous anodic alumina, is observed.

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The ceramide contents of Saccharomyces cerevisiae in batch culture (Saccharomyces cerevisiae 의 회분식 배양에서 세라마이드의 생산)

  • Kim, Se-Kyung;Noh, Yong-Ho;Yun, Hyun-Shik
    • KSBB Journal
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    • v.23 no.5
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    • pp.449-451
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    • 2008
  • Ceramide has become a widely used ingredient in cosmetic and pharmaceutical industries, however, only a few yeast strains were investigated for the synthesis of ceramide and the concentration was very low. Ceramide is not only a core intermediate of sphingolipids but also an important modulator of many cellular events including apoptosis, cell cycle arrest, senescence, differentiation, and stress responses. In this study S.cerevisiae was grown in a batch culture and the cellular content of ceramide was measured at different growth phases. The ceramide content was highest at stationary phase and 2.01 mg ceramide/g cell was obtained.

Coarsening Effects on the Formation of Microporous Membranes

  • Song, Seung-Won
    • Proceedings of the Membrane Society of Korea Conference
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    • 1995.04a
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    • pp.1-4
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    • 1995
  • The microstructure of polymer membranes produced via thermally induced phase separation (TIPS) of polymer solutions is a strong function of both the early-stage (by spinodal decomposition or nucleation & growth) and the late-stage phase separation (referred to in general as coarsening). In the case of early stage effects, the membrane morphology resulting from a nucleation & growth mechanism is either a poorly interconnecsed, stringy, beady structure which is mechanically fragile or a well interconnected structure with highly nonuniform pore sizes. In contrast, spinodal decomposition results in a well interconnected, mechanically strong membrane with highly uniform pore sizes. Here I describe recent quantitative studies of the coarsening effects on the microstructure of membranes produced via TIPS process. The dependence of microstructure on coarsening time, quench depth, solution viscosity, and polymer molecular weight was investigated in order to distinguish among three possible coarsening mechanisms, Ostwald ripening, coalescence, and hydrodynamic flow, which may be responsible for structural evolution after the early-stage phase Separation (spinodal decomposition or nucleation & growth).

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The Effect of Government's Fairness as the Entrepreneur's Satisfactions & Managerial Performance: Focusing on the Differences between Start-up Companies' Growth Stage (정부의 창업지원 공정성이 만족도 및 경영성과에 미치는 영향: 창업기업의 성장단계별 차이를 중심으로)

  • Jang, Younghye;Lee, Jeonghye;Kim, Pansoo
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.15 no.4
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    • pp.109-120
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    • 2020
  • This study examines how the government's fairness in entrepreneurship support affects satisfaction and management performance, and examines whether these influences are different for each growth stage of start-up companies. For this study, data were collected for start-up companies that received government support for start-up within the past 5 years. Total 611 copies of the data were used in this study. The collected data were analyzed using SPSS and AMOS. The fairness used in this study was divided into three types, procedural fairness, interactive fairness, and distributed fairness. The effect of the three fairness on the satisfaction of start-up support project was analyzed. In addition, the effect of business support satisfaction on business performance was analyzed, where the business performance was evaluated by the questioner's satisfaction with their business. The start-up phase was divided into the start phase, early growth phase, stagnant phase, and high-level growth phase, and the moderating effect between the fairness and satisfaction of the government-supported projects by start-up phase was analyzed. As a result, it was found that every concept of fairness had a positive (+) effect on the satisfaction of the entrepreneurship support project, and the satisfaction of the entrepreneurship support project had a positive (+) effect on the management performance. The concept of procedural fairness in the start phase, procedural fairness in the early growth phase, interactive fairness, and the concept of all fairness in the stagnant phase influenced the satisfaction of the start-up support project. In this study, the fairness and effect of government-supported projects affecting the management performance of start-ups were identified by growth phase of start-ups. The results of these studies will help build a systematic system for entrepreneurship support and for start-ups, it will also greatly contribute to finding differentiated growth plans by growth stages of start-up companies.

The Transient Simulation of Czochralski Single Crystal Growth Process Using New Solidification Model (새로운 응고 모델을 적용한 Czocgralski 단결정 성장 공정 모사)

  • 이경우;윤종규
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.1 no.1
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    • pp.74-81
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    • 1991
  • The temperature profile of Czochralski single crystal growth system was simulated considering the fluid flow and surface radiation heat transfer. View factors of surface elements were calculated for radiation heat transfer. Two phases(solid and liquid) were treated as a continuous phase by assigning artificial large viscosity to the solid phase and latent heat was accounted by iterative heat revolution method. The solidification model was applied to solid front of the pure Ga during the melting to verify the model. The whole simulation model of CZ system was applied to the growth Al single crystal.

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Influence of Amino Acid and Vitamin Addition on the Growth and Metabolism of a Hybridoma in Batch Culture (하이브리도마의 회분식배양에서 아미노산과 비타민의 첨가에 따른 세포성장과 대사의 변화)

  • 이동섭;박홍우
    • KSBB Journal
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    • v.13 no.3
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    • pp.289-294
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    • 1998
  • The effects of various step-fortifications of the initial medium with amino acids, glucose, and vitamines on the growth and metabolism of a hybridoma cell line in batch cultures were quantified. Comparisons between the metabolic rates of the various cultivations were made for the exponential growth phase. Fortification of the basal medium resulted in higher cell densities through a prolonged growth phase, but the maximum specific growth rate was not affected. The uptake rate of glutamine increased with the addition of amino acids but did not change upon the addition of glucose or vitamines. The specific glucose consumption decreased slightly with the addition of amino acids but increased production of lactate and {{{{ { NH}`_{4 } ^{ +} }}}}. A reciprocal relationship between the yields of {{{{ { NH}`_{4 } ^{+ } }}}} and lactate indicated a joint regulation of glycolysis and glutaminolysis.

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A Study of Intermetetallic Compound Growth in the Sn/Ni Couples(I) : Intermetallic Compound Formation and Growth Kineties (Sn/Cu 및 Sn/Ni 계면에서 금속간화합물의 형성 및 성장에 관한 연구(I) : 금속간화합물의 생성, 성장반응 및 속도론)

  • 김용혁;이성래
    • Journal of Surface Science and Engineering
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    • v.22 no.1
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    • pp.3-9
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    • 1989
  • The intermetallic compount formation, growth rections, and growth kinetices as functions of the aging temperaturess, time, and the condition of substarte have invedtigted in the Sn/Cu and Sn/Ni bimetal couples. The η'-phase (Cu6Sn5) and $\delta$-phase (Ni3Sn4) were only found to grow at 20 and $70^{\circ}C$in the Sn/Cu and Sn/Ni bimetallic coples repectively. Above that temperatures, all other compounds were formed in sequence of high Sn content plase and the metastable Cu41Sn11 was formed at agend $200^{\circ}C$. The ectivation energy for the growth of intermetallic compounds was 14.7Kxal/mole in the Sn/Cu interface and 26.7Kcal/mole in the Sn/Ni interface.

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Optimization of Switching Time from Growth to Product Formation for Maximum Productivity of Recombinant Escherichia coli Fermentation (유전자 재조합 대장균 발효의 최대 생산성을 위한 생육에서 제품 생성으로 전환시기의 최적화)

  • Anant Y. Patkar
    • Microbiology and Biotechnology Letters
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    • v.18 no.4
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    • pp.394-400
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    • 1990
  • Maximization of productivity of recombinant cell fermentations requires consideration of the inverse relationship between the host cell growth rate and product formation rate. The problem of maximizing a weighted performance index was solved by using optimal control theory for recombinant E. coli fermentation. Concentration of a growth inhibitor was used as a control variable to manipulate the specific growth rate, and consequently the cloned-gene expression rate. Using a simple unstructured model to describe the main characteristics of this system, theoretical analysis showed that the optimal control profile results in an initial high growth rate phase followed by a low growth rate and high product formation rate phase. Numerical calculations were done to determine optimal switching times from the growth to the production stage for two representative cases corresponding to different dependency of the product formation rate on the growth rate. For the case when product formation rate is sensitive to the specific growth rate, the optimized operation yields about 60% increase in the final product concentration compared with a simple batch fermentation.

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The Influence of Phase Feeding Methods on Growth Performance, Meat Quality, and Production Cost in Growing-Finishing Pigs (성장단계별 사료급여 방법이 육성-비육돈의 성장과 육질 그리고 생산비에 미치는 영향)

  • Jeong, Tae-Sam;Heo, Pil-Seung;Lee, Geon-Young;Kim, Dong-Hyuk;Ju, Won-Seok;Kim, Yoo-Yong
    • Journal of Animal Science and Technology
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    • v.52 no.1
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    • pp.29-36
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    • 2010
  • This experiment was conducted to evaluate the influence of phase feeding methods on growth performance, carcass characteristics, pork quality, and economical efficiency in growing-finishing pigs. A total of 120 crossbred pigs ([Yorkshire ${\times}$ Landrace] ${\times}$ Duroc), average initial body weight 25.23 ${\pm}$ 2.66 kg, were allotted to 5 treatments by body weight and sex in a randomized complete block (RCB) design. Each treatment had 6 replicates with 4 pigs per pen. The treatments were 1) A (fed late weaner feed during whole phase), 2) B (fed late weaner feed in growing phase and grower feed in finishing phase), 3) C (fed grower feed during whole phase), 4) D (fed grower feed in growing phase and early finisher feed in early and late finishing phase), 5) E (fed grower feed in growing phase, early finisher feed in early finishing phase and late finisher feed in late finishing phase). Commercial diets bought from private feed company were used for this experiment. During the early growing phase (6 wks), treatments A and B showed higher growth performance than that of other treatments (P<0.05). However, growth performance tended to be similar among treatments at 10 wks after feeding and there was no difference in time of market weight (13 wks). Moreover, blood urea nitrogen (BUN) concentration was lowered in treatment E than other treatments during whole experimental period (P<0.01). Carcass characteristics and pork quality were measured when body weight of pigs reached at 110.33 ${\pm}$ 2.1 kg. Days to market weight (110 kg), quality grade, pork color, and pork pH did not show any significant difference among treatments. These results suggested that phase feeding based upon growth stages of pigs showed no detrimental effects on growth performance and the pork quality. Moreover, feed cost was saved approximately 37% by phase feeding method without delaying of days to market weight compared to general conventional feeding method (B) of swine farm in Korea.

Effects of Methylglyoxal on the Growth Dynamics of Secenedesmus quadricauda (Methylglyoxal 이 Scenedesmus quadricauda 의 성장 역학에 미치는 영향)

  • Rhie, Ki-Tae
    • The Korean Journal of Ecology
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    • v.18 no.1
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    • pp.17-30
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    • 1995
  • The growth of Scenedesmus quadricauda (Trup.) Breb. is enhanced by methylyoxal (MG), a general inhibitor of cell division, at threshold concentration in conjunction with reatment timing relative to growth stage. The stimulatory effect of MG on algal cell growth was most significant with 2.27-fold of untreated algal culture in cell number when 0.5 mM of MG was added to the algal culture at the beginning of logarithmic phase with an initial MG concentration of 0.535 mg $MG/10^6cell$. A Specific growth rates (SGRs) of MG-treated cultures were rapidly increased at the beginning of logarithmic phase with 1.89-fold of untreated algal culture. Cultures inoculated with high cell numbers of 2.4 to 4.8 X $10^4$ cells/ml were less sensitive to 0.5 mM of MG treatment. The algal cell division was ranged from 0.392 to 0.924 mg MG/106 cell. If the cell number of an algal culture at the time of inoculation was low (0.6 X $10^4$ cells/ml) and MG was added before logarithmic phase, the cell number of 0.5 mM of MG-treated cultures were lower than those of controls. In algal cultures treated with high concentrations of MG (1.0 mM and 2.0 mM), the algal growth was inhibited. Photosynthetic rate of growth-enhanced algal by 0.5 mM of MG was significantly higher than that of untreated or 1.0 mM of MG-treated algal cell, while there was no significant difference among those groups in respiratory rate. Pyruvate concentration in 0.5 mM of MG-treated culture was incrcased agter methylglyoxal trcatment.

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