• 제목/요약/키워드: growth modeling

검색결과 876건 처리시간 0.024초

Geometric and mechanical properties evaluation of scaffolds for bone tissue applications designing by a reaction-diffusion models and manufactured with a material jetting system

  • Velasco, Marco A.;Lancheros, Yadira;Garzon-Alvarado, Diego A.
    • Journal of Computational Design and Engineering
    • /
    • 제3권4호
    • /
    • pp.385-397
    • /
    • 2016
  • Scaffolds are essential in bone tissue engineering, as they provide support to cells and growth factors necessary to regenerate tissue. In addition, they meet the mechanical function of the bone while it regenerates. Currently, the multiple methods for designing and manufacturing scaffolds are based on regular structures from a unit cell that repeats in a given domain. However, these methods do not resemble the actual structure of the trabecular bone which may work against osseous tissue regeneration. To explore the design of porous structures with similar mechanical properties to native bone, a geometric generation scheme from a reaction-diffusion model and its manufacturing via a material jetting system is proposed. This article presents the methodology used, the geometric characteristics and the modulus of elasticity of the scaffolds designed and manufactured. The method proposed shows its potential to generate structures that allow to control the basic scaffold properties for bone tissue engineering such as the width of the channels and porosity. The mechanical properties of our scaffolds are similar to trabecular tissue present in vertebrae and tibia bones. Tests on the manufactured scaffolds show that it is necessary to consider the orientation of the object relative to the printing system because the channel geometry, mechanical properties and roughness are heavily influenced by the position of the surface analyzed with respect to the printing axis. A possible line for future work may be the establishment of a set of guidelines to consider the effects of manufacturing processes in designing stages.

기상자원 측정을 위한 와이파이 기반의 풍력용 데이터로거 시스템에 관한 연구 (A Study on a Wind Turbine Data Logger System based on WiFi for Meteorological Resource Measurement)

  • 정세훈;심춘보
    • 한국전자통신학회논문지
    • /
    • 제10권1호
    • /
    • pp.55-64
    • /
    • 2015
  • 풍력시장은 매년 연 30%정도의 고도 성장률을 보이고 있으며, 점차 늘어나고 있는 추세이다. 국내 풍력발전기 설치 총량은 380MW로 전 세계시장의 0.2%의 점유율을 보이고 있다. 그러나 국내에 설치된 풍력발전기의 90%이상이 해외기업 제품이다. 또한 해상 풍력 발전소 설치를 위한 사전 조사 시스템에 적용되는 데이터로거도 대부분 해외기업 제품으로 막대한 비용이 해외로 유출되는 실정이다. 이에 본 논문에서는 풍력 발전기건설 업무의 효율성과 투자 비용절감을 위한 사전 기상자원 측정 시스템을 제안한다. 사전 기상자원 측정 시스템은 기상탑의 기상 관측 데이터로거 H/W와 무선 브리지, 기상탑 주변의 풍향, 풍속, 온 습도, 일사량, 데이터로거의 전력 상태를 모니터링할 수 있며, 측정된 데이터를 분석할 수 있는 Wind Rose S/W로 구성된 무선 통신(Wifi)기반의 해양 기상자원 측정 데이터로거 및 분석 모니터링 시스템이다.

유한요소해석을 이용한 가스터빈 발전기 로터의 계자권선 변형 해석 (Investigation of the Coil Deforamtion of the Gas Turbine Generator Rotor Using Finite Element Analysis)

  • 윤완노;박현구;강명수;김준성
    • 동력기계공학회지
    • /
    • 제13권6호
    • /
    • pp.95-101
    • /
    • 2009
  • The generator for gas turbine power generation consists of the rotor which generates magnetic field, the winding coil which is the path for the field current and the wedge and retaining ring which prevents the radial movement of the coil. Relatively severe deformation was observed at the coil end section during the inspection of the generator for peaking-load operation, and the thermal-electricity and the centrifugal force were evaluated by the simple modeling of the windings to find the cause. But the simulation stress was not sufficient to induce the coil plastic deformation. The analysis result seems to be applicable to the base-load generators which runs continuously without shut down up to a year, but there had been more deformation than simulated for the generator which is started up and shut down frequently. The cause of the coil deformation was the restriction of the expansion and shrinkage. The restriction occurs when the winding coil shrinks, and the stress overwhelms the yield stress and cause the plastic deformation. The deformation is accumulated during the start-ups and shut-downs and the thermal growth occurs. The factors which induce the coil restriction during the expansion and shrinkage should be reduced to prevent the unallowable deformation. The resolutions are cutting off the field current earlier during the generator shut-down, modifying the coil end section to remove the stress concentration and making the insulation plate inserted between the coil end section and the retaining ring have the constant thickness.

  • PDF

대형 수목의 이식공법 - 천안시 팽나무와 안동시 은행나무 사례 - (A Study on the Transplantation Methods of Large Trees - The Case of Celtis Sinensis in Chonan and Ginkgo biloba in Andong -)

  • 임재홍;이재근;김학범
    • 한국조경학회지
    • /
    • 제30권4호
    • /
    • pp.92-104
    • /
    • 2002
  • This study investigates, analyzes, and summarizes Dansplantation techniques and methods through practical methodology centering on fieldwork in order to present effective planting methods for large trees that have important significance. The conclusions are as follows : 1. The transplantation process of a large tree generally consists of the stages of digging up a tree, manufacturing a carrier frame, loading the tee on a vehicle, transporting, transplanting the tree, installing a strut and maintaining and managing the new transplant. In addition, planting a tree on a mounted place includes the primary procedures of trimming out the root, and preparing for transplanting the tree on a mounted place, as well as the secondary work of trimming out the root, transplanting a tree on a mounted place, maintenance and management. 2. In order to decide on a transplantation method for a large-sized tree, a structure calculation has to be performed first. That is, one must calculate the weight of the tree and the allowable stress of the strut (H-beam, etc.) fhst and then decide on the upper method through computer modeling based upon this structural calculation. 3. As a result of the analysis of a transplanted tree using the life soil method, it was confirmed that large quantities of feeder roots had developed around the root within a short time after the transplantation. The life soil method has proven to be very effective for transplantation of large-sized trees. 4. As for the production method of an H-beam strut frame, it was found that the manufacturing process and disassembly process were simple and proper; therefore, the H-beam frame is an appropriate structure to be used in the transplantation of large trees. 5. The concavo-convex method, which consists of filling the life soil in the concavo-convex area around the root, was found to be a method that promotes the growth of feeder roots within a short period of time and saves the supply of water at the same time.

동역학적 흡착 관계식을 이용한 다공 매질에서의 유동세균에 의한 유기성 오염물의 가속이송 예측 모델 (Modeling Bacteria Facilitated Contaminant Transport in Porous Media with Kinetic Adsorption Relationships)

  • 김승현
    • 대한지하수환경학회지
    • /
    • 제2권1호
    • /
    • pp.22-29
    • /
    • 1995
  • 유동 세균 입자는 지체계수를 감소시키므로써 지하수에서 소수성 오염물의 이동을 촉진시킨다. 그 크기와 표면의 적당한 물리화학적 조건으로 인하여 세균은 효율적인 오염물의 운반자가 될 수 있다. 이러한 운반자가 있을 때, 그 계는 액상, 입상, 그리고 고상의 3 상으로 해석되어야한다. 오염물은 각 상에 모두, 혹은 그 중의 일부에 존재할 수 도 있다. 본 연구에서는 세균이 있는 경우, 생화학적으로 분해 가능한 유기성 오염물의 다공매질에서의 거동을 물질수지에 기초하여 수학적 모델로 묘사한다. 세균의 액상과 고상사이의 물질 전이 및 오염물의 액상과 입상사이의 물질 전이는 동역학적 관계식으로 나타냈다. 모델 결과를 일반화하기 위하여 무차원화를 수행했고, 그 해를 구하여 세균에 의한 오염물의 가속이송 효과를 알 수 있었다. 모델 결과는 문헌상의 실험결과와 비교되었다. 모델 결과로부터 오염물은 그 계의 Damkohler I 수가 10 이상일 경우 국지 평형 가정을 할 수 있었으며, 세균의 성장율과 주입 농도 등이 오염물의 청소에 아주 중요한 요소임을 알 수 있었다.

  • PDF

영아 자녀를 둔 어머니의 양육스트레스 변화가 온정적 양육행동 및 유아의 사회정서발달에 미치는 영향: 어머니 취업여부에 따른 차이 (The Effects of Maternal Parenting Stress Trajectory on Affective Parenting and Socioemotional Development of Preschooler: Differences Between Employed and Unemployed Mothers)

  • 박새롬;박혜준
    • 아동학회지
    • /
    • 제37권5호
    • /
    • pp.33-52
    • /
    • 2016
  • Objective: This study aimed to investigate the trajectory of maternal parenting stress during infancy according to the employment status of mothers when each year's depression was controlled and examine the longitudinal effects of parenting stress on affective parenting and socioemotional developmental outcomes for preschoolers. Methods: Using latent growth modeling, the first 4 waves of panel data collected from 2,078 mothers and their babies were analyzed. This nationwide data was provided from the 2008 Panel Study on Korean Children, conducted by the Korea Institute of Child Care and Education. Results: First, maternal parenting stress showed a linear increasing pattern, and there were individual differences in intercept and slope. Second, when each year's maternal depression was controlled, the intercept of parenting stress was lower, but the rate of increase was higher. In multiple group analyses, this increasing pattern of parenting stress was significant only in unemployed mothers. Lastly, the increase of unemployed mothers' parenting stress had direct effects on child emotionality and peer interaction and had an indirect effect on child peer interaction (mediated by affective parenting). Conclusion: The current study verified that the longitudinal effects of increasing parenting stress of unemployed mothers on affective parenting and child socioemotional development when maternal depression level was controlled. These results imply that we need to pay more attention to emotional health and resources of unemployed mothers and provide them with social support as well as employed mothers.

Social Business 참여에 영향을 주는 내.외재적 특성과 심리적 계약의 조절효과에 대한 실증연구 (An Empirical Study on the Influence of Internal and External Characteristics on the Social Business Participation and the Moderating Effects of Psychological Contract)

  • 김상현;김근아
    • 한국IT서비스학회지
    • /
    • 제10권4호
    • /
    • pp.1-19
    • /
    • 2011
  • Following the growth of e-Business, there has been a recent increase of interest in promoting Social Business (s-Business) based on Social Network Service(SNS). As the introduction of the Internet brought about the increasing number of its users followed by the growing market of e-Commerce, online games, and e-Learning, the increasing number of SNS users has opened the new markets combining the existing industrial fields with SNS, and it developed into a revenue model beyond the mere sharing of information. Despite such industrial and social environments, understanding of new social business technology from the aspect of business has been insufficient, and the empirical study on participation in the social business has been scant as well. Thus, the main purpose of this study is to investigate the s-Business in detail and to study the factors giving influence to the users' participation in s-Business. This study proposes six variables(Self-Empowerment, Job Relevance, Formation of Social Capital, Relative Advantage, Shared Value, Relationship Specified Investment) and the moderating effects of Psychological Contract as influential factors closely related with s-Business. A total of 362 data from a survey were analyzed by using Structural Equation Modeling(SEM). Result showed that all factors with the exception of Job Relevance have meaningful influence on the intention to participate in s-Business. The implication of the findings suggests to compliment limitations of the existing researches, and to prepare the theoretical foundation for promoting s-Business participation in addition to further suggesting directionality from the view point of the users of the social business-relevant studies.

구조 생물학을 이용한 Antifreeze protein의 최근 연구동향 (Recent Advances in Structural Studies of Antifreeze Proteins)

  • 이준혁;이성구;김학준
    • Ocean and Polar Research
    • /
    • 제33권2호
    • /
    • pp.159-169
    • /
    • 2011
  • Antifreeze proteins (AFPs) have ice binding affinity, depress freezing temperature and inhibit ice recystallization which protect cellular membranes in polar organisms. Recent structural studies of antifreeze proteins have significantly expanded our understanding of the structure-function relationship and ice crystal growth inhibition. Although AFPs (Type I-IV AFP from fish, insect AFP and Plant AFP) have completely different fold and no sequence homology, they share a common feature of their surface area for ice binding property. The conserved ice-binding sites are relatively flat and hydrophobic. For example, Type I AFP has an amphipathic, single ${\alpha}$-helix and has regularly spaced Thr-Ala residues which make direct interaction with oxygen atoms of ice crystals. Unlike Type I AFP, Type II and III AFP are compact globular proteins that contain a flat ice-binding patch on the surface. Type II and Type III AFP show a remarkable structural similarity with the sugar binding lectin protein and C-terminal domain of sialic acid synthase, respectively. Type IV is assumed to form a four-helix bundle which has sequence similarity with apolipoprotein. The results of our modeling suggest an ice-binding induced structural change of Type IV AFP. Insect AFP has ${\beta}$-helical structure with a regular array of Thr-X-Thr motif. Threonine residues of each Thr-X-Thr motif fit well into the ice crystal lattice and provide a good surface-surface complementarity. This review focuses on the structural characteristics and details of the ice-binding mechanism of antifreeze proteins.

공공도서관의 정보검색대행서비스를 위한 서비스모형화 및 기대효과에 관한 연구 (A Study on Service Modeling for IR Agency Service in a Public Library and Its Expectations)

  • 김용;김태경
    • 한국문헌정보학회지
    • /
    • 제40권1호
    • /
    • pp.195-215
    • /
    • 2006
  • 정보기술과 인터넷의 발전은 정보의 대량생산과 함께 정보검색의 대중화를 가져왔으며, 검색포털사이트의 성장은 정보이용자들에게 정보를 획득할 수 있는 유일한 정보원으로서의 도서관에 대한 인식의 변화를 가져 왔다. 이용자들은 검색포털사이트를 보다 편리하고 다양한 정보를 획득할 수 있는 효과적인 정보원으로 각인하고 선호하게 되었다. 이러한 사회환경의 변화 속에서 도서관과 사서는 이용자의 정보요구에 보다 적극적이고 현실성 있는 정보서비스를 제공함으로써 그 사회적 역할과 위상을 정립하고 진일보할 수 있는 도전과 기회로 삼아야 할 것이다. 이를 위하여 본 연구에서는 도서관, 특히 공공도서관의 적극적인 정보서비스 방안으로서 정보검색대행서비스를 제안하고, 이러한 서비스의 가능성과 기대효과를 정보이용자에 대한 직접 설문을 통하여 조사하였다. 특히 대부분의 이용자들이 친숙하고 편리하게 이용할 수 있는 전화와 PDA등을 활용한 정보서비스에 대한 가능성 및 방법론에 대하여 제안하고자 한다.

알바 알토(Alvar Aalto)의 유기적 디자인 특성에 관한 연구 (A Study on the Characteristics of Organic Design of Alvar Aalto)

  • 이종선
    • 한국실내디자인학회논문집
    • /
    • 제12호
    • /
    • pp.91-99
    • /
    • 1997
  • Alvar Aalto has pursued National Romanticism, cultural art movement in scandinavian peninsula, organic concepts of growth and suitability, comprehensive view of nature including a possibility of coexistance of human-being and the nature well harmonized. For instance, his design expressed local features of the nature, human emotions instead of geometical arts and mathematical principles. It is noteworthy today that he built up the identity with satrical architecture vocabularies, different from modern arch-itechtural idiology. The characte-ristics of his design related to interior architecture are collectively as follows; The first, Space discontinuity of the interior and exterior, gradual process by joints which are inclined to collage with many shapes in plan and section of the space and such joints are adjusted by sensual ways and stressed with inner collectivity in his works. The second, He pursued the architectural orderfor modern irreqularity, various changes and sensual harmonies. As result, free curved line, fan shape and irregular modeling were individually expressed by technics of natural features and national characteristics of Finland. The third, Organic synthesis. A harmony through med-ums in its space, materials and space effectiveness relations are made and expressed for mixed design especially harmonized of all the materials he planned, entire harmony with total design, itemized details, materials and furnitures in entire space. The fourth, The interest of the nature based on his sense harmonized with nature made him mainly use native materials, lumbers and red bricks masonry and showed and arranged various interior sky light and grazed in to let natural light in, harmony with garden to sensually cohere to the nature and courtyard, etcetera. His major subject are to direct architectural developments through the nature and human-being in his works. At this point, it is considered that his direction of the locality and independence as a human-being made the concepts of organic space structure possible.

  • PDF