• Journal of mucopolysaccharidosis and rare diseases
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• 제2권2호
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• pp.38-40
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• 2016

Prader-Willi syndrome (PWS) is a rare genetic disorder often caused by a deletion of the chromosome 15q11-q13 region inherited from the father or by maternal disomy 15. Growth hormone deficiency with short stature, hypogonadism, cognitive and behavioral problems, analgesia, decreased gastric motility and decreased ability to vomit with hyperphagia are common in PWS leading to severe obesity in early childhood, if not controlled. The goal of this study is to investigate the effects of recombinant human GH (rhGH, henceforth designated GH) on the gene expression related to cognitive function in the brain of PWS mouse model (Snord116del). GH restored the mRNA expression level of several genes in the cerebellum. These data suggest the effect of GH on the expression of cognitive function related genes in cerebellum may provide a mechanism for the GH-induced brain function in PWS patients.

• 지역연구
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• 제14권2호
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• pp.65-75
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• 1998

Education is widely recognized one of main sources for growth. This paper attempts to incorporate the general recognition into formal regional growth model. The model structure is largely neoclassical. It produces a single good with the two factors, educated labor and non-educated labor, via a constant return production migrating to the region with the higher real wage. The educated labor in a region is accumulated by two sources, migration and physical education capital, while the non-educated labor is by only migration. The paper shows that regional growth equilibrium is characterized as a saddle point. This indicates the presence of the minimum threshold size that must be overcome before a region may grow. It contrasts sharply with results obtained in regional growth models. The paper suggests that regional growth is determined less by the technical characteristics of regional production function characteristics of regional production function but by the stock combination of educated function but by the stock combination of education labor and non-educated labor. Based on this result, the impact of agglomeration economies on regional growth is explored. It is by phase diagram demonstrated that the presence of agglomeration economies do not always lead a region to growth since there still exists the minimum threshold even in the presence of agglomeration economies.

• 호남수학학술지
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• 제45권1호
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• pp.42-53
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• 2023

The main aim of this paper is to introduce the definition of 𝜑-proximate order of a meromorphic function on the complex plane. By considering the concept of 𝜑-proximate order, we will extend some previous results of Lahiri [11]. Furthermore, as an application of 𝜑-proximate order, a result concerning the growth of composite entire and meromorphic function will be given.

• KSBB Journal
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• 제13권6호
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• pp.730-734
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• 1998

An이ew식과 Aiba삭을 조합하여 에탄올 생산단주인 Saccharomyces cerevisiae ATCC 24858의 비성장속도를 당농도와 에탄올 농도의 함수로 표현하였다. 기침의 저해영향을 받지 않는 최대 당농도 $S_m$은 150 g/L이며 기질의 저해영향은 기질농도 S와 $S-S_{max}$항의 함수로 표현되었다. 최대 비성장 속도 ${\mu}max 는 0.49 hr^{-1}, Monod상수 K_s$는 19 g/L, Andrew식의 기질저해상수 $K_1$는 139 g/L이였다. 또한 비성장속도에 영향을 마치지 앓는 최대알콜농도 Pm이 존재하였으며 그 값은 2 g/L 이였다. 따라서 Aiba식에서 비성장속도에 영향을 미치는 에탄올 농도항은 P-Pm으보 표현되었다. 본 연구의 알코올생산균주에 대한 비성장속도의 완성된 수식은 디음과 같으며 이 수식에 위한 계산값은 평균오차 6% 내외의 범위에서 실험값과 일치하였다.

• 통상정보연구
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• 제10권1호
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• pp.329-347
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• 2008

The purpose of this study is to examine the causal relationship between the exchange rate and economic growth, and to induce policy implications. In order to test whether time series data is stationary and the model is fitness or not, we put in operation unit root test, cointegration test. And we apply Granger causality based on an error correction model. The results indicate that uni-dierctional causality between exchange rate and economic growth is detected. Exchange rate impacts on economic growth, but economic growth don't impact on exchange rate. The analysis of impulse reaction function shows that the impulse of exchange rate impacts on Korean economic growth in negative direction. We can infer policy suggestion as follows: The fluctuation of exchange rate much affects economic growth, thus we must make a stable policy of exchange rate to continue economic growth.

• 정보처리학회논문지D
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• 제13D권5호
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• pp.709-716
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• 2006

소프트웨어 복잡도가 증가할수록 소프트웨어 성공률은 기하급수적으로 감소하며, 반대로 실패율은 증가한다. 소프트웨어 규모 증가에 따른 실패율은 성장곡선으로 표현할 수 있다. 이 현상에 따라, 본 논문은 Gompertz 성장곡선으로 개발 성공률과 완료율을 추정하였다. 먼저, 수치적으로 제시된 $10^n$의 소프트웨어 규모를 로그값으로 변환시켜 데이터 간격을 일정하게 하였다 로그값의 소프트웨어 규모 변화에 따른 개발 성공률과 완료율의 함수관계를 유도하고자 하였다. 그러나 이 관계를 적절히 표현하는 함수를 찾지 못하였다. 따라서 본 논문에서는 개발 성공률의 역 개념인 실패율과 완료율의 역 개념인 취소율을 도입하였다. 로그값의 소프트웨어 규모 변화에 따른 개발 실패율과 취소율 관계는 성장곡선 형태를 나타내었다. 결론적으로, 개발 취소율과 실패율을 적절히 표현하는 함수로 Gompertz 성장곡선을 적용한 결과 실측 데이터를 적절히 표현할 수 있었다. 본 모델을 적용하면 특정 규모의 소프트웨어에 대한 개발 성공률과 완료율을 보다 정확히 얻을 수 있을 것이다.

• 품질경영학회지
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• 제34권3호
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• pp.73-78
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• 2006

In this paper, we propose a software reliability growth model based on the testing domain in the software system, which is isolated by the executed test cases in software testing. In particular, our model assumes an imperfect debugging environment in which new faults are introduced in the fault-correction process, and is formulated as a nonhomogeneous Poisson process(NHPP). Further, it is applied to fault-detection data, the results of software reliability assessment are shown, and comparison of goodness-of-fit with the existing software reliability growth model is performed.

• KDI Journal of Economic Policy
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• 제39권4호
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• pp.25-50
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• 2017

Whereas a large variety of previous studies show mixed results regarding the relationship between public investment and economic outcome, several studies have been conducted on related issues in Korea. The present study deals with the effect of public investment in Korea on economic growth and productivity. Using administrative data, it exploits three different methodologies: the total factor productivity approach, production function approach, and stochastic frontier production function approach. The results of this study show that public investment has a statistically significant effect on economic growth. However, it contributes little to enhance productivity. It is explained that there exists inefficiency of production in the Korean economy. These findings indicate that public investment has played a central role in the direct input factor and not in indirect role in Korea. Thus, it is necessary for public investment policies to concentrate on enhancing the efficiency of the Korean economy.

• Clinical and Experimental Pediatrics
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• 제52권2호
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• pp.142-151
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• 2009

The incidence of small for gestational age (SGA) births is frequent, accounting for 2.3% to 8% of all live births. Several childhood and adult diseases are related to early postnatal growth and birth size, and 10% of children born SGA may have a short stature throughout postnatal life. Additionally, they may have abnormal growth hormone (GH)-insulin like growth factor axis, HPA axis, and gonadal function. Permanent changes are detrimental in an environment of nutritional abundance, and predispose SGA children to an array of diseases in adolescence and adulthood. Such changes may also cause premature pubarche, adrenarche, and precocious puberty. The varying results from clinical studies necessitate more prospective case control studies. Reproductive tract abnormalities and reproductive dysfunction are related to SGA births. GH treatment is required for SGA infants who do not experience catch-up growth.

• 한국연초학회지
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• 제3권2호
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• pp.109-114
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• 1981

This experiment was conducted with three varieties (Hicks, Burley 21, Sohyang) and cropping systems (Improved mulching, Mulching, Non mulching) of NC 2326 to analyze growth kinetics by means of growth function involving its velocity and accelerated velocity. The basic growth data were obtained by harvest method at interval of ten days from transplanting to hundred days and analyzed by , regression equation, determinant of matrix, and differentiation. The plot of total dry weight of leaves, stalk and roots per a plant vs. time forms a sigmoid curve and its function fitted logistic satisfactorily. Tobacco plant grows at an accelerated velocity. And growth velocity, symmetric about an inflection point, is proportional to biomass attained and to the difference between biomass attained and the maximum, and to the decrease according to the biomass. Of varieties and cropping systems, the most maximum velocity was 9.58g per day per plant in mulching cultivation of NC 2326 and maximum accelerated velocity was 264mg per $day^2$ per plant in Burley 21.