• 여성건강간호학회지
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• 제16권2호
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• pp.157-165
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• 2010

Purpose: The purpose of this study was to identify differences in Health Locus of Control (HLOC), depression, wellbeing, and Health Promoting Lifestyle Profile II (HPLP) between middle aged Korean and Korean-American women. Methods: Data from 80 Korean-American women living in Los Angeles, USA and 82 Korean women living in W-city, Korea, were collected using a self administered questionnaire including items on HLOC, HPLP, a Wellbeing Index and Major Depression Inventory. Results: There were statistically significant differences between the middle aged Koreans and Korean-Americans on mean age, education, religion, and current health insurance. Significant differences were found on HLOC (F= 2.504, p=.033) and Wellbeing (F=2.451, p=.036). The results also showed significant differences on HPLP (total HPLP, F=4.655, p=.001; physical activity, F=2.967, p=.014; nutrition, F=4.250, p=.001; spiritual growth, F=4.398, p=.001; interpersonal relations, F=2.648, p=.025; and stress management, F=5.201, p<.001) using ANCOVA. However, there were no significant differences on depression, or health responsibility in HPLP between the groups. Conclusion: Understanding middle aged women's health adjustments based on their culture will enhance the ability of health professionals to provide culturally congruent care and enable middle aged women to develop healthy lifestyles.

• 여성건강간호학회지
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• 제20권1호
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• pp.14-28
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• 2014

Purpose: This study was to identify relationships of maternal psychosocial factors including mother's mood state, childcare stress, social support and sleep satisfaction with breastfeeding adaptation and immune substances in breast milk, especially secretory immunoglobulin A (sIgA) and transforming growth factor-beta 2 (TGF-${\beta}2$). Methods: Data were collected from 84 mothers who delivered full-term infants by natural childbirth. Structured questionnaires and breast milk were collected at 2~4 days and 6 weeks postpartum. Data were analyzed using descriptive statistics, Pearson's correlation, multiple linear regression, and generalized estimating equation (GEE). Results: Scores for the breastfeeding adaptation scale were significantly related with child care stress, mood state and social support. Mother's anger was positively correlated with the level of sIgA in colostrum (p<.01). Immune substances of breastmilk was significantly influenced by time for milk collection (p<.001) and the type of breastfeeding (sIgA, p<.001, TGF-${\beta}2$, p=.003). Regression analysis showed that breastfeeding adaptation could be explained 59.1% by the type of breastfeeding, childcare stress, the Profile of Mood States, emotional support and sleep quality (F=16.67, p<.001). Conclusion: The findings from this study provide important concepts of breastfeeding adaptation program and explanation of psychosocial factors by immune substances in breast milk. Future research, specially, bio-maker research on breast milk should focus on the ways to improve breastfeeding adaptation.

• 대한금속재료학회지
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• 제49권10호
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• pp.818-822
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• 2011

ZnO nanorods were grown on Au-coated Si substrates by vapor phase transport (VPT) at the growth temperature of $600^{\circ}C$ using a mixture of zinc oxide and graphite powders as source material. Au thin films with the thickness of 5 nm were deposited by ion sputtering. Temperature-dependent photoluminescence (PL) was carried out to investigate the optical properties of the ZnO nanorods. Five peaks at 3.363, 3.327, 3.296, 3.228, and 3.143 eV, corresponding to the free exciton (FX), neutral donor bound exciton ($D^{\circ}X$), first order longitudinal optical phonon replica of free exciton (FX-1LO), FX-2LO, and FX-3LO emissions, were obtained at low-temperature (10 K). The intensity of these peaks decreased and their position was red shifted with the increase in the temperature. The FX emission peak energy of the ZnO nanorods exhibited an anomalous behavior (red-blue-red shift) with the increase in temperature. This is also known as an "S-shaped" emission shift. The thermal activation energy for the exciton with increasing temperature in the ZnO nanorods is found to be about 26.6 meV; the values of Varshni's empirical equation fitting parameters are = $5{\times}10^{-4}eV/K$, ${\beta}=350K$, and $E_g(0)=3.364eV$.

• 대한의용생체공학회:의공학회지
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• 제40권5호
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• pp.165-170
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• 2019

Cancer cells are different from normal cells in terms of life cycle, behavior, and growth patterns. Cancer cells can migrate freely in the body through blood vessels and lymph nodes. The cancer cells easily interact with various substrates including extracellular matrix and vessels and they can differentiate in the new environment. However, it is not well known about the adhesion preference of cancer cells on the substrate and the mechanism of their interaction. In this study, we prepared the nano-, micro-patterned substrates using E-beam lithography techniques. MCF-7 cells were tested on the substrates to find out their adhesion preference. The substrates were made by polydimethylsiloxane (PDMS) with specific patterns including pillars with a diameter of 500 nm, 700 nm, $3{\mu}m$ and $5{\mu}m$. MCF-7 cells were seeded on the substrates and incubated for 24 hours. As a result, this study clearly demonstrated that the MCF-7 cells preferred 700 nm patterning.

• Mycobiology
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• 제47권3호
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• pp.308-318
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• 2019

Bio-sulfur can be produced in the process of desulfurization from a landfill and collected by some microorganism such as Thiobacillus sp. as a sulfur element. In order to investigate practical use of bio-sulfur as an agent for controlling plant disease, in vitro antifungal activity of bio-sulfur was tested against Colletotrichum orbiculare known to cause cucumber anthracnose. Efficacy of bio-sulfur for suppressing anthracnose disease was also evaluated in vivo using cucumber leaves. Mycelial growth of C. orbiculare on medium containing bio-sulfur was inhibited. Disease severity of cucumber leaves pre-treated with bio-sulfur was significantly decreased compared to that of untreated ones. To illustrate how bio-sulfur could suppress anthracnose disease, structures of cucumber leaves infected with C. orbiculare were observed under a fluorescent microscope and a scanning electron microscope (SEM). Cucumber leaves pre-treated with bio-sulfur showed a low rate of appressorium formation whereas untreated ones showed abundant appressoria. Shrunk fungal hyphae were mostly observed on bio-sulfur-pretreated leaves by SEM. Similar results were observed on leaves pre-treated with a commercial fungicide Benomyl(R). These results suggest that inhibition of appressorium formation of C. orbiculare by bio-sulfur may contribute to its suppression of cucumber anthracnose.

• 약학회지
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• 제48권3호
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• pp.189-196
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• 2004

Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) playa key role in tumor invasion and metastasis. As an inhibitor of MMP-2, TIMP-2 is known to block both the invasive and metastatic behavior of cancer cells, and decrease tumor growth activity. We performed this study to investigate the effects of TIMP-2 over-expression induced by retroviral mediated gene transfer in vitro and in vivo. The human colon cancer cell line SW480 was transfected with the retroviral vector encoding TIMP-2. The effects of TIMP-2 over-expression were analyzed by invasion assay and gelatinase activity test in colon cancer cells and tumorigencity in nude mice. In evaluation of the transfection efficiency of the retroviral vector encoding TIMP-2 in colon cancer cells, we confirmed up-regulation of TIMP-2 expression dependent on the time of cell culture. In addition, inhibition of MMP-2 expression in SW480/TIMP-2 was shown by gelatin zymography. In the in vitro invasion assay SW480/TIMP-2 inhibited the invasiveness on matrigel coated with collagen. To determine whether TIMP-2 can modulate in vivo tumorigenicity and metastasis, SW480/TIMP-2 cells were injected subcutaneously in nude mice. The tumor mass formation of SW480/TIMP-2 cells in nude mice was markedly decreased compared to nontransfected cancer cells. These results showed that colon cancer cells transfected with the retroviral vector encoding TIMP-2 inhibits the invasiveness in vitro and tumorigenicity in vivo.

• Nuclear Engineering and Technology
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• 제19권2호
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• pp.122-129
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• 1987

핵연료 피복재 (Zircaloy-4)에 생기는 얇은 산화층의 두께에 따른 고온에서의 산화 거동을 관찰하기 위하여 실험과 수치 계산을 수행하였다. 산화 실험은 수중기와 물의 혼합 분위기에서 지르칼로이-4판재 시편을 $650^{\circ}C$에서 600초, 1,800초 동안 산화시켜서 산화층을 형성시킨 후 $700^{\circ}C$ 와 85$0^{\circ}C$ 사이의 온도에서 산화 거동을 관찰하였다. 기산화층의 두께가 두꺼울수록 고온에서의 산화율은 as-received cladding의 경우보다 낮았다. 기산화층이 형성된 시편에서는 산화율 천이 영역이 나타났으며 이 영역은 산화 온도가 올라감에 따라 점차로 소멸되었다. 기산화층의 영향은 낮은 온도($700^{\circ}C$)에서 가장 뚜렷하게 나타났다. 수치 계산 결과에 의하면, 산화층 증가율과 무게 증가는 실험 결과와 비슷하게 기산화층의 두께에 영향을 받았다.

• 한국학교보건학회지
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• 제30권3호
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• pp.317-324
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• 2017

Purpose: Breakfast is the most important meal to provide energy for the day. Breakfast is especially important to give enough nutritional support to children and adolescents for their physical growth and sexual development. Sleep-related factors like average sleep duration and wake up time would mostly be associated with regular breakfast. This study aimed to investigate the effect of sleep on regular breakfast consumption in Korean adolescents. Methods: The study used the data from the 12th Korea Youth Risk Behavior Web-based Survey (KYRBS-XII) conducted in 2016 by the Korea Centers for Disease Control and Prevention. The data of 62,820 subjects (middle/high school students) were included in the final analysis. The study examined the factors related to regular breakfast, focusing on weekday average sleep duration and wake up time of middle school students and high school students, respectively. Results: Regular breakfast consumption was shown to have a statistically significant association with high economic status, nutritional education, weekday average sleep duration, wake up time, and subjective sleep satisfaction in the multivariate logistic regression. Regardless of the school level, regular breakfast consumption was significantly associated with early wake up time. As to the effect of weekday average sleep duration on regular breakfast consumption, it showed some different results depending on the school level. Conclusion: Regular breakfast consumption of Korean adolescents was related to weekday average sleep duration and wake up time. Having breakfast regularly was affected by both adequate weekday average sleep duration and early wake up time.

• 한국학교보건학회지
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• 제30권3호
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• pp.355-364
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• 2017

Purpose: The purpose of this study was to identify health promotion behaviors of elementary school teachers and investigate the factors influencing the health promotion behaviors. Methods: Data were collected from 234 elementary school teachers in the B Metropolitan City Office of Education from 5th to 30th October, 2016. The collected data were analyzed by descriptive statistics, t-test, ANOVA, $Scheff{\acute{e}}$ test, Mann-Whitney test, Kruskal-Wallis test, Spearman correlation coefficient and multiple regression analysis, using SPSS/WIN 23.0. Results: The elementary school teachers' health perception scored 2.94 out of 4, health status 1.59 out of 3, and health promotion behaviors 2.66 out of 4. The level of mental health status (1.67) was higher than that of physical health status (1.54) and the most practiced health promotion behavior was spiritual growth (3.15) and the least was health responsibility (2.00). Significant negative correlations were found between health perception and health status (r=-.59, p<.001) and between health status and health promotion behaviors (r=-.41, p<.001). A significant positive correlation was found between health perception and health promotion behaviors (r=.32, p<.001). The significant factors influencing health promotion behaviors were job stress and health status. These factors explained 19.6% of the health promotion behaviors. Conclusion: It is necessary to establish measures to increase the health perception and health promotion behaviors of elementary school teachers and improve their health status. In addition, since job stress and health status are factors influencing health promotion behaviors, it is necessary to actively manage job stress and health status in order to increase health promotion behaviors.

• 한국안전학회지
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• 제34권4호
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• pp.1-5
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• 2019

In the field of combined cycle power generation, thermal barrier coating(TBC) protects the super-heat-resistant alloy, which forms the core component of the gas turbine, from high temperature exposure. As the turbine inlet temperature(TIT) increases, TBC is more important and durability performance is also important when considering maintenance cost and safety. Therefore, studies have been made on the fabrication method of TBC and super-heat-resistant alloy in order to improve the performance of the TBC. In recent years, due to excellent properties such as high temperature creep resistance and high temperature strength, turbine blade material have been replaced by a single crystal superalloy, however there is a lack of research on TBC applied to single crystal superalloy. In this study, to understand the isothermal degradation performance of the TBC applied to the single crystal superalloy, isothermal exposure test was conducted at various temperature to derive the delamination life. The growth curve of thermally grown oxide(TGO) layer was predicted to evaluate the isothermal degradation performance. Also, microstructural analysis was performed by scanning electron microscope(SEM) and energy dispersive X-ray spectroscopy (EDS) to determine the effect of mixed oxide formation on the delamination life.