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Diagnosis of Work-related Musculoskeletal Disease through Moire Image Pattern and Treatment Measure using a Sling System (Moire' 영상무늬를 통한 근골격계질환의 진단과 현가장치를 이용한 치료방안)

  • Lee Sang-Yong;Lee Eun-Kyong;Kwon So-Hee;Jung He-Kyong;Kim Sam-Tae;Chong Myong-Soo;Lee Ki-Nam
    • Journal of Society of Preventive Korean Medicine
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    • v.7 no.2
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    • pp.121-130
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    • 2003
  • The Musculoskeletal Disease has been ignored or turned away due to the difficulty of diagnosis and the vagueness of judgement up to now. Contrary to other diseases, there were many cases where the character of the Musculoskeletal Disease wasn't revealed through the objective inspection. And that's because the Musculoskeletal Disease appears for the most part due to muscular defect so it is impossible to diagnose the muscle by X-ray diagnosing the bone and it is also impossible to diagnose the fine damage of the muscle or tendon even by advanced device like MRI. As the nervous blood vessels or acupunctures pass through or are next to the muscle, the tension of the muscle put pressure on these so can become the direct or indirect causes of various kinds of pains or intern diseases. But in spite of that, for lack of proper equipment diagnosing the state of the muscle(Shortened.. Relaxed... or Hardened...) the muscle has been disregarded or neglected intentionally or unintentionally. While many people think themselves to be a muscular expert, if they don't see the shape of the muscle, that is just like blind treatment. But as now the equipment diagnosing the state of the muscle is developed, it seems that this problem can be settled. It was attempted in this study that the muscle or skeleton of the Musculoskeletal disease patients was diagno the treatment order and method were decided by a questionnaire survey and simple inspection, and the Musculoskeletal correction exercise using the muscle management and sling system made them escape from the Musculoskeletal disease, turning their muscle into more flexible and stronger muscle. As a result notwithstanding the limited treatment period '12 times', the improvement rate was as high as 74%, which showed that the muscle management and Musculoskeletal correction exercise had a great effect on the symptom improvement of the patients. If the treatment times had increased, the improvement rate also would have increased more.

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Strategies for the development of GM crops in accordance with the environmental risk assessment (I) (환경위해성 평가를 고려한 GM작물의 개발 전략 (I))

  • Lee, Shin-Woo
    • Journal of Plant Biotechnology
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    • v.38 no.2
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    • pp.125-129
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    • 2011
  • Environmental risk assessment (RA) is essential prior to the environmental release of GM crops. RA, however, costs at least 7 to 15 million US dollars and requires several years to complete field tests. Therefore, it is strongly suggested that developers of GM crops must consider all criteria for RA at the beginning stage of the development if it aims for commercialization. Previous review papers have pointed out that the "death valley" for the commercialization of GM crops is the screening stage of early GM events since many candidates are given up due to insufficient data on the molecular characterization of a GM event such as inserted gene's copy number, position of inserted site of a chromosome, flanking sequence of recombinant T-DNA, rearrangement of chromosome, and knock out of endogenous gene of host plant. Recently, Rural Development Administration (RDA) in South Korea has launched a Grand National Project named as "Next Generation of BioGreen 21 Project" from 2011 to 2020 and research funding for the development of global GM crops has been allocated to accelerate the commercialization of GM crops. In this regard, I strongly suggest that researchers involved in the development of GM crops for commercialization must conduct RA by themselves at the screening stage of pre-GM event based on the data for molecular characterization.

The Development of Image Processing System Using Area Camera for Feeding Lumber (영역카메라를 이용한 이송중인 제재목의 화상처리시스템 개발)

  • Kim, Byung Nam;Lee, Hyoung Woo;Kim, Kwang Mo
    • Journal of the Korean Wood Science and Technology
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    • v.37 no.1
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    • pp.37-47
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    • 2009
  • For the inspection of wood, machine vision is the most common automated inspection method used at present. It is required to sort wood products by grade and to locate surface defects prior to cut-up. Many different sensing methods have been applied to inspection of wood including optical, ultrasonic, X-ray sensing in the wood industry. Nowadays the scanning system mainly employs CCD line-scan camera to meet the needs of accurate detection of lumber defects and real-time image processing. But this system needs exact feeding system and low deviation of lumber thickness. In this study low cost CCD area sensor was used for the development of image processing system for lumber being fed. When domestic red pine being fed on the conveyer belt, lumber images of irregular term of captured area were acquired because belt conveyor slipped between belt and roller. To overcome incorrect image merging by the unstable feeding speed of belt conveyor, it was applied template matching algorithm which was a measure of the similarity between the pattern of current image and the next one. Feeding the lumber over 13.8 m/min, general area sensor generates unreadable image pattern by the motion blur. The red channel of RGB filter showed a good performance for removing background of the green conveyor belt from merged image. Threshold value reduction method that was a image-based thresholding algorithm performed well for knot detection.

A Case of Carbamoyl Phosphate Synthetase 1 Deficiency with a Relatively Good Prognosis Presented in the Late Neonatal Period (신생아 후기에 증상을 발현하여 비교적 양호한 예후를 보이는 Carbamoyl Phosphate Synthetase 1 Deficiency 1례)

  • Park, Esther;Kim, Min-sun;Song, Ari;Im, Min Ji;Jang, Ja-Hyun;Kim, Ji Hye;Cho, Sung Yoon;Jin, Dong-Kyu
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.18 no.1
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    • pp.23-29
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    • 2018
  • Carbamoyl phosphate synthetase 1 deficiency (CPS1D) is a rare autosomal recessive urea cycle disorder characterized by hyperammonemia. CPS1D is caused by mutations in the CPS1 gene on chromosome 2q35. Based on the age of onset, there are two phenotypes: the neonatal type and the delayed-onset type. The severity of clinical manifestation depends on the degree of CPS1 residual enzymatic activity, and can result in hyperammonemia and neurological dysfunction. We report a case of CPS1D in a neonate who developed vomiting, decreased consciousness and hyperammonemia at 25th day after birth. She showed excellent response to treatment including hydration, ammonia-lowering drugs and a low-protein diet without hemodialysis. Her growth, development and neurological outcomes were fair at the last follow-up at 17 months of age.

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The Effect of Silica binder content ans Sintering condition on the Strength of Zircon-based Shell Mold (실리카 바인더 함량과 소결조건이 지르콘계 주형의 강도에 미치는 영향)

  • Kim, Jae-Won;Kim, Du-Hyeon;Kim, In-Su;Seo, Seong-Mun;Jo, Hae-Yong;Kim, Du-Su;Jo, Chang-Yong;Choe, Seung-Ju
    • Korean Journal of Materials Research
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    • v.10 no.6
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    • pp.415-421
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    • 2000
  • The effect of silica binder content on the mechanical properties of zircon shell mold was investigated. Content of binder silica sol to refractory powder in weight[$R_W$] was adjusted from 0.18 to 0.43. Sintering of the shell mold was carried out in the temperature range of $871^{\circ}C$ to $1400^{\circ}C$. Green strength of the shell mold at room temperature increased with increasing $R_W$ and sintering temperature up to $1300^{\circ}C$. However, the mold with $R_W$ of 0.43 that sintered at $1400^{\circ}C$ for 3 hours showed relatively low strength and large level of porosity. The mechanical behavior of the shells is supposed to attributed to the difference in thermal expansion coefficient between refractory powder and binder silica. The optimum value of $R_W$ for zircon-based shell molds was found to be 0.33.

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Development of a Framework for Evaluating Water Quality in Estuarine Reservoir Based on a Resilience Analysis Method (회복탄력성 분석 기반 담수호 수질 평가 프레임워크 개발)

  • Hwang, Soonho;Jun, Sang Min;Kim, Kyeung;Kim, Seok Hyun;Lee, Hyunji;Kwak, Jihae;Kang, Moon Seong
    • Journal of The Korean Society of Agricultural Engineers
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    • v.62 no.5
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    • pp.105-119
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    • 2020
  • Although there have been a lot of efforts to improve water quality in the estuarine reservoir, overall the water quality problems of the estuarine reservoirs remain. So, it is essential to establish water quality management plans under a comprehensive understanding of the environmental characteristics of the estuarine reservoir. Therefore, in this study, a resilience analysis framework for evaluating the estuarine reservoir's water quality was suggested for improving existing assessment method for water quality management plan. First, as a result of analyzing the static resilience to each scenario, it was found that from the S3 scenario in which dredging was conducted considerably, the resilience of about 30% more than the current estuarine reservoir system was restored. Second, as a result of analyzing the dynamic resilience, if cost and time are considered, there is no significant difference in robustness and resourcefulness, so it can be seen that the resilience of the estuarine reservoir can be efficiently improved by simply performing dredging up to the level of Scenario 3. Finally, as a result of comparing static and dynamic resilience, since static resilience is only presented as a single value, the differences and characteristics of the resilience capacity of the estuarine reservoir might be overlooked only by the static resilience analysis. However, in the aspect that it is possible to interpret the internal recovery capacity of the estuarine reservoir in multiple ways with various indicators (robustness, redundancy, resourcefulness, rapidity), evaluating water quality based on dynamic resilience analysis is useful.

Evaluation of Alginate Microspheres Prepared by Emulsion and Spray Method for Oral Vaccine Delivery System (유화법과 분무법에 의해 제조된 경구백신용 알긴산 마이크로스피어의 평가)

  • Jiang, Ge;Jee, Ung-Kil;Maeng, Pil-Jae;Hwang, Sung-Joo
    • Journal of Pharmaceutical Investigation
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    • v.31 no.4
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    • pp.241-256
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    • 2001
  • Alginate microspheres, containing fluorescein isothiocyanate-bovine serum albumin (FITC-BSA) or green fluorescent protein (GFP) were prepared and used as a model drug to develop the oral vaccine delivery system. The alginate microspheres were coated with poly-L-lysine or chitosan. Two methods, w/o-emulsion and spray, were used to prepare alginate microspheres. To optimize preparation conditions, effects of several factors on the particle size and particle morphology of microsphere, and loading efficiency of model antigen were investigated. In both preparation methods, the particle size and the loading efficiency were enhanced when the concentration of sodium alginate increased. In the w/o-emulsion preparation method, as the concentration of Span 80 was increased from 0.5% to 2%, the particle size was decreased, but the loading efficiency was increased. The higher the emulsification speed was, the smaller the particle size and loading efficiency were. The concentration of calcium chloride did not show any effect on the particle size and loading efficiency. In the spray preparation method, the particle size was increased as the nozzle pressure $(from\;1\;kgf/m^2\;to\;3\;kgf/m^2)$ and spray rate was raised. Increasing calcium chloride concentration (<7%) decreased the particle size, in contrast to no effect of calcium chloride concentration on the w/o-emulsion preparation method. Alginate microspheres prepared by two methods were different in the particle size and loading efficiency, the particle size of microspheres prepared by the spray method was about $2-6\;{\mu}m$, larger than that prepared by the w/o emulsion method $(about\;2{\mu}m)$, and the loading efficiency was also higher with spray method. Furthermore, drying process for the microspheres prepared by the spray was simpler and easier, compared with the w/o emulsion preparation. Therefore, the spray method was chosen to prepare alginate microspheres for further experiments. Release pattern of FITC-BSA in alginate microspheres was evaluated in simulated intestinal fluid and PBS (phosphate buffered saline). Dissolution rate of FITC-BSA from alginate/chitosan microsphere was lower than that from alginate microsphere and alginate/poly-L-lysine microsphere. By confocal laser scanning microscope, it was revealed that alginate/FITC-poly-L-lysine microspheres were present in close apposition epithelium of the Peyer's patches of rabbits following inoculation into lumen of intestine, which proved that microspheres could be taken up by Peyer's patch. In conclusion, it is suggested that alginate microsphere prepared by spray method, showing a particle size of & $10\;{\mu}m$ and a high loading efficiency, can be used as a model drug for the development of oral vaccine delivery system.

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Evaluation of Characteristics of Anisotropic Deformation in Manufacturing of Large-scale Glass-ceramic Composite Sintered Body (대형 유리-세라믹 복합 매질 소결체 제조 시 비등방성 변형 특성 평가)

  • Kim, Kwang-Wook;Sohn, Sungjune;Kim, Jimin;Foster, Richard I.;Lee, Keunyoung
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.18 no.1
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    • pp.31-41
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    • 2020
  • We studied the anisotropic shrinkage and deformation characteristics of large size sintered bodies in the manufacturing of glass-ceramic composite wasteform. We used uranium-bearing waste, generated from the treatment of spent uranium catalyst. Sintered specimens were prepared in several forms, comprising a circular disk, and a quarter disk in several diameters of up to 40 cm. Regardless of form or size, the sintered bodies had high isotropic shrinkage when they were fabricated using green bodies prepared at 60 MPa. The average anisotropy rate and average shrinkage rate were 1.6%, and 37.4%, respectively. We confirmed that the glass-ceramic composite wasteform in a large scale disk-type for packing in a 200 L drum could be fabricated with a tolerable anisotropy shrinkage. This has resulted in a significant reduction in the volume of radioactive waste to be disposed of with highly stable wasteform.

Translocation of $^14$C-assimilates During Grain Filling and Influence of Defoliation and Emasculation on Grain Weight in Oats (연맥 등숙기 동안 $^14$C물질의 전유와 절엽 및 제영이 종실중에 미치는 영향)

  • 이호진
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.24 no.4
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    • pp.38-44
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    • 1979
  • $^14$C-sucrose was labeled on detached panicles and $^14{CO}_2$ on flag leaves or panicles of intact plants to study grain sink activity in spring oats cultivar Pennfield. Defoliation and emasculation experiment was conducted to study source-sink relationship during grain filling. Specific activity of groat rose up to 15 days after anthesis and declined rapidly to 18 days. Daily gain of groat wt. matched closely with specific activity of. groat during grain filling. Primary groats were higher in specific activity of groat than secondary groats.$^14{CO}_2$ exposure on panicle was three times higher in specific activity of groat than $^14{CO}_2$exposure on flag leaf. In the defoliation and emasculation experiment, groat wt. of Pennfield oats decreased as ratio of source/sink decreased. Half number of spikelets with half leaf area was no different in groat wt. compared to control, but normal number of spikelets with zero leaf area was decreased 16% in groat wt., indicating a significant compensation by green area on panicle.

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Physical and Sensory Properties of Peeled Ginkgo Nuts Prepared under the Different Dehydration Conditions (내피제거 은행의 물리적 및 관능적 품질 특성)

  • Han, Jae-Young;Lee, Young-Chun;Kim, Kwang-Ok
    • Korean Journal of Food Science and Technology
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    • v.35 no.1
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    • pp.84-91
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    • 2003
  • The effects of different dehydration conditions for the removal of ginkgo nut inner coat on peeled ginkgo nuts were examined using physical and sensory methods. Dehydration of ginkgo nuts at $90^{\circ}C$ for 120 min resulted in greater hardness, lightness (L), redness (a), yellowness (b), and firmness. Higher roasted flavor and larger holes were observed with dehydration at $150^{\circ}C$ for 30 min and greater cooked ginkgo flavor and green color with dehydration at $120^{\circ}C$ for 50 min. Based on these findings, dehydration at $120^{\circ}C$ for 50 min was determined as the adequate hot air dehydration condition for the removal of ginkgo nut inner coat. Ginkgo nuts stored at $25^{\circ}C$ maintained overall desirability up to 4 weeks. In ginkgo nuts stored at $4^{\circ}C$, all sensory desirabilities evaluated were reasonably high until 60 days of storage; desirability of appearance decreased moderately at 80 days of storage, and appearance became very undesirable at 180 days. Ginkgo nuts stored at $-18^{\circ}C$ showed little changes until 10 months of storage, but slight decreases in overall desirability, flavor, and texture were noted at 12 months.