• Title/Summary/Keyword: granule size

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The Effect of Sodium Alginate Coating on the Storage Stability and Dissolution Rate of Enteric Coated Lansoprazole (알긴산 나트륨이 장용코팅된 란소프라졸 제제의 저장안정성 및 용출률에 미치는 영향에 관한 연구)

  • Kim, Jung-Hoon;Oh, Jung-Min;Khang, Gil-Son;Jeong, Je-Kyo;Lee, Jung-Sik;Jeung, Sang-Young;Lee, Hai-Bang
    • Journal of Pharmaceutical Investigation
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    • v.32 no.4
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    • pp.277-284
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    • 2002
  • Lansoprazole, pharmaceutics for acid-related diseases, is unstable in low pH environments and generally coated with enteric polymer to obtain gastroresistance in stomach. Because its storage stability is influenced by acidic substitutes of enteric polymer, alkaline chemicals wεre generally addεd to dosage form as a stabilizer. In this experience, we coated lansoprazole bead with sodium alginate and evaluated the effect of bead size and sodium alginate coating on the storage stability and dissolution profile of lansoprazole. Sodium alginate solution containing lansoprazole was sprayed as a droplet into 3% (w/v) $CaCl_2$ solution and the resultant bead was coated with starch, sodium alginate, and hydroxypropyl methylcellulose phthalate. The content of lansoprazole granule not coated with sodium alginate decreased to 57.96% of initial content when stored at a severe condition for 4 weeks, but that of lansoprazole granule coated with sodium alginate before enteric coating decreased little and as the thickness of sodium alginate film increased, the content of bead didn't decreased for 4 weeks. Sodium alginate film also improved the gastroresistance without much influencing the maximum dissolution rate.

Comparison of Physicochemical Properties of Legume Starches (두류전분의 이화학적 특성 비교)

  • Kweon, Mee-Ra;Ahn, Seung-Yo
    • Korean Journal of Food Science and Technology
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    • v.25 no.4
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    • pp.334-339
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    • 1993
  • Physicochemical properties such as amylose content, swelling power, gelatinization and DSC of legume starches were investigated. The granule shape of legume starches was oval. The size of cowpea and mung bean were smaller than kidney bean and red bean. The amylose content of mung bean and kidney bean was larger and were $25{\sim}29%$. Swelling power of kidney bean starch was much lower than other starches in all temperature range. In gelatinization temperature by Brabender amylogram, red bean starch was low, but kidney bean starch was rather high. Amylographic hot-paste viscosity and set back of cow pea, mung bean and red bean starches were high. But those of kidney bean starch were very low. DSC results Indicated kidney bean starch gelatinized in higher temperature. From above results, row pea and mung bean starches were similar in granule size and shape, solubility and swelling power, amylogram, and DSC thermogram. But kidney bean starch was very different and red bean starch was slightly different with the physicochemical properties of cow pea and mung bean starches.

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Influence of Harvest Time on Pasting Properties of Starch in Colored Rice

  • Kim, Sang-Kuk;Song, Young-Un;Kim, Se-Jong;Shin, Jong-Hee
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.62 no.4
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    • pp.311-316
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    • 2017
  • The relationship between mean air temperature after heading and starch characteristics of colored rice grains was investigated using three colored rice cultivars. Pasting temperature within each rice cultivar with different harvest times differed. The pasting temperatures of two rice cultivars, Hongjinju and Joseongheugchal, reached the highest at 40 days after heading and decreased during the late harvest time. Distribution of amylopectin in the Hongjinju rice cultivar at the earlier harvest time contained a greater number of very short chains with the degree of polymerization (DP) between 6 and 12 and fewer chains with a DP from 13 to 24 than that of the later harvest time. However, there was little difference in the distribution of the longer chains of $25{\leq}DP{\geq}36$ and $37{\leq}DP$ for latter harvest times compared to that of the earlier ones. It was suggested that the structure of amylopectin affected the varietal differences in patterns of chain length of amylopectin during grain filling. In addition, the control of ripening was different from that causing the pigment effects in the fine structure of amylopectin in the three colored rice cultivars. Larger starch granules were observed in the Joseongheugchal rice cultivar and smaller granules occurred in the Hongjinju rice cultivar. The present study revealed that later harvest times led to a clear increase in the mean granule size of starch in the three colored rice cultivars.

Rice as an alternative feed ingredient in swine diets

  • Kim, Sheena;Cho, Jin Ho;Kim, Hyeun Bum;Song, Minho
    • Journal of Animal Science and Technology
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    • v.63 no.3
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    • pp.465-474
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    • 2021
  • It has become important to explore alternative feed ingredients to reduce feed costs, which are burdensome for livestock production. In addition, it is desirable to find efficient and functional alternative ingredients for traditional feed ingredients in pig diets, considering the stress and sensitivity of disease of pig. Rice is produced around the world like corn that is the typical energy source in pig diets. Although the nutritional quality varies depending on the degree of milling, rice, except whole grains (paddy rice), contains more starch than corn and its structure and granule size are easier to digest than corn. In addition, the fact that rice has fewer non-starch polysaccharides (NSP) and anti-nutritional factors (ANFs) is also effective in improving digestibility and various polyphenols in rice can help modulation of immune responses, which can be beneficial to the gastrointestinal environment and health of pig. Many studies have been conducted on rice focusing on things such as degree of milling, substitution rates of corn, granule size, and processing methods. Most results have shown that rice can be partially or completely used to replace corn in pig diets without negatively affecting pig growth and production. While further research should focus on the precise biological mechanisms at play, it was confirmed that the use of rice could reduce the use of antibiotics and pig removal and protect pigs from gastrointestinal diseases including diarrhea. From this point of view, rice can be evaluated as a valuable feed ingredient for swine diets.

Herbicidal Efficacy and Diffusibility of 500g Great Granule for Remote-Controlled Aerial Application in Paddy Rice (농용 무인항공방제용 500g 대립제의 잡초방제효과와 확산성)

  • Yoon, Cheol-Su;Lee, Sheong-Chun;Kim, Kyung-Hyun;Lee, Kye-Hwan;Seok, Chang-Soo;Kim, Hyun-Jae;Cho, Tae-Kyoung;Hwang, In-Cheon
    • Korean Journal of Weed Science
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    • v.30 no.4
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    • pp.445-453
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    • 2010
  • This study was conducted to investigate herbicidal efficacy and diffusibility of halosulfuron-methyl+mefenacet in water treated with 500 g great granule (GG) and 3 kg granule (GR). The 500 g GG was been spreading on the surface of the water within 6 minutes, 53 seconds, and it's active ingredient was diffused in the water bath of $10m^2$ size between 30 and 60 minutes. In addition, the diffusion of 500 g GG was influenced by moisture contents, so it have to immediately use 500 g GG in paddy fields when it was been unpacked. The herbicidal efficacy of the 500 g GG and 3 kg GR of halosulfuron-methyl+mefenacet was excellent to most weed species, but showed different efficacy for the control of Aneilema keisak and Scirpus juncoides, that was may be distribution pattern of active ingredient as different formulation.

Review on the Korean Terms of Sediment Grain Size Demonstrated in the Textbooks (교과서에서 사용하는 퇴적물의 입도에 대한 한국어 용어의 검토)

  • Kim, Jeong-Yul
    • Journal of the Korean earth science society
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    • v.33 no.4
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    • pp.350-359
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    • 2012
  • The Korean terms of sediment grain size demonstrated in the 30 textbooks of elementary, middle, and high schools and university levels are compared and reviewed, and the problems of its use and alternative terms are proposed. The Korean terms of sediment grain size shown in the most textbooks are the translated terms of the Udden-Wentworth grade scale, and the different terms have been used in these textbooks. In the case of gravels, granule, cobble, and boulder have commonly been translated as wangmorae (king sand), janjagal (fine gravel), wangjagal (king gravel), and pyoryeog (drift gravel) or georyeog (large gravel), respectively. However, it is regarded to be reasonable that they are termed as janjagal, jungjagal (medium gravel), keunjagal (large gravel), and wangjagal, respectively. Adjectives such as 'maeu goun' (very fine), 'goun' (fine), 'junggan' (medium), 'gulgeun' (coarse), and 'maeu gulgeun' (very coarse), attached with each sediment name seem to be suitable to terms for sediments smaller than gravels. Silt has been commonly termed as misa (fine sand) in many textbooks, but it may be appropriate that silt is expressed as silt. Finally, mud, which is a mixture of silt and clay, should be named ito (mud) as shown in several textbooks including Dictionary of Korean Earth Science, though mud has been frequently termed as jinheug (slush or watery soil) in the most of textbooks for elementary and middle school students, and some high school and university textbooks.

Preparation of Spherical Granules of Dolomite Kiln Dust as Gas Adsorbent

  • Choi, Young-Hoon;Huh, Jae-Hoon;Lee, Shin-Haeng;Han, Choon;Ahn, Ji-Whan
    • Journal of the Korean Ceramic Society
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    • v.53 no.1
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    • pp.13-17
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    • 2016
  • It is highlighted that increasing the adsorbent surface area on volumetric basis is very important in providing an easy access for gas molecules. Fine particles around $3{\mu}m$ of soft-burned dolomite kiln dust (SB-DKD) were hydrated to wet slurry samples by ball mill process and then placed in a chamber to use spray dryer method. Spherical granules with particle size distribution of $50{\sim}60{\mu}m$ were prepared under the experimental condition with or without addition of a pore-forming agent. The relationship between bead size of the pore-forming agent and size of SB-DKD particles is the most significant factor in preparation of spherical granules with a high porosity. Whereas addition of smaller beads than SB-DKD resulted in almost no change in the surface porosity of spherical granules, addition of larger beads than SB-DKD contributed to obtaining of the particles with both 15 times larger average pore volume and 1 order of magnitude larger porosity. It is considered that spherical granules with improved $N_2$ gas adsorption ability may also be utilized for other atmospheric gas adsorption.

A Grain Size Analysis of Bottom Sediments of Yeongil Bay, Korea (한국 영일만 해저퇴적물의 입도분포)

  • Park, Byong-Kwon;Song Moo-Young
    • 한국해양학회지
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    • v.7 no.2
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    • pp.74-85
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    • 1972
  • This paper studied the grain size distribution of bottom sediments of Yeongil Bay which is located at the southeastern part of the Korean Peninsula. Sixty four samples collected with snapper and dredger are analyzed by roe Tap Sieve Shaker and Pipette Method. The moment parameters are calculated with the method of Friedman(1961). Most samples are composed of sand size sediments and a few samples are composed of silt and clay. The Yeongil Bay can be divided into gravel-granule zone, sand zone, and silt-clay zone. The sediments near Yeonam- Dong and Hyongsan river are moderately sorted and others are very poorly sorted according to scheme of Friedman91962). In general, sorting values are ranged from 1.0 to 3.5. The samples near Janggigap and Masin-Dong show negative and others show positive skewness values. Skewness values are ranged from -1 to 2. All samples show the leptokurtic distribution except for the samples near Masin- dong and at the deepest place near Janggigap. Kurtosis values are ranged from -1.5 to 21.9. The samples of gravel-granule zone contain more than 50% and those of silt-clay zone contain less than 50% of CaCO$\_$3/. Four different colors, black, yellow, brown and gray, are shown in the sediments of Yeongil Bay.

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The Prodessing Control of NiCuZn Ferrite(II) - The Relationship between Initial Permeability and Bulk Density of NiCuZn Ferrite as Functions of Forming Pressure and Sintering Temperature. (NiCuZn Ferrite의 제조공정 제어(제2보) - 성형압력 및 소성온도 변화에 따른 초기투자율과 겉보기밀도에 관한 고찰)

  • 류병환;김선희;최경숙;고재천
    • Journal of the Korean Magnetics Society
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    • v.5 no.6
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    • pp.937-946
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    • 1995
  • In this research, the processing control of NiCuZn Ferrite has been developed. The relationship between initial permeability and bulk density of NiCuZn Ferrite with processing factors was studied. NiCuZn Ferrite, which calcinated at $700^{\circ}C$ for 3 hours, was ball milled for about 60 hours to make a size of $0.5\mu\textrm{m}$ followed by granulation using spray dryer. The physical properties and the magnetic properties of NiCuZn Ferrite were investigated with the processing factor, such as (i) granule size and forming pressure, and (ii) sintering temperature. The green density of NiCuZn Ferrite was largely depended on the forming pressure rather than its granule size. The green density of NiCuZn Ferrite was increased from $2.484\;g/cm^{3}$ to $3.002\;g/cm^{3}$ with increase in forming pressure. The bulk density of NiCuZn Ferrite was increased from $3.470\;g/cm^{3}$ to $4.754\;g/cm^{3}$ linearly with increase in sintering temperature. The relationship between initial permeability and bulk density of NiCuZn Ferrite was expressed with the empirical equation,$\mu_{i}=a+b_{\rho}+c_{\rho}^2$ at forming pressure and sintering temperature.

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Effect of the Holding Temperature and Vacuum Pressure for the Open Cell Mg Alloy Foams

  • Yue, Xue-Zheng;Hur, Bo-Young
    • Korean Journal of Materials Research
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    • v.22 no.6
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    • pp.309-315
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    • 2012
  • Metal foam has many excellent properties, such as light weight, incombustibility, good thermal insulation, sound absorption, energy absorption, and environmental friendliness. It has two types of macrostructure, a closed-cell foam with sealed pores and an open-cell foam with open pores. The open-cell foam has a complex macrostructure consisting of an interconnected network. It can be exploited as a degradable biomaterial and a heat exchanger material. In this paper, open cell Mg alloy foams have been produced by infiltrating molten Mg alloy into porous pre-forms, where granules facilitate porous material. The granules have suitable strength and excellent thermal stability. They are also inexpensive and easily move out from open-cell foamed Mg-Al alloy materials. When the melt casting process used an inert gas, the molten magnesium igniting is resolved easily. The effects of the preheating temperature of the filler particle mould, negative pressure, and granule size on the fluidity of the open cell Mg alloy foam were investigated. With the increased infiltration pressure, preheat temperature and granule sizes during casting process, the molten AZ31 alloy was high fluidity. The optimum casting temperature, preheating temperature of the filler particle mould, and negative pressure were $750^{\circ}C$, $400-500^{\circ}C$, and 5000-6000 Pa, respectively, At these conditions the AZ31 alloy had good fluidity and castability with the longest infiltration length, fewer defects, and a uniform pore structure.