• Bulletin of the Korean Chemical Society
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• 제34권1호
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• pp.237-242
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• 2013

This experiment was conducted for the purpose of developing such a sensor that can quickly sense dopamine concentration by using chitosan-gold nanoshell. Chitosan nano particles were reacted with gold nano particles so as to synthesize chitosan-gold nanoshell, and the size of the synthesized product was about 150 nm. When dopamine was reacted with chitosan-gold nanoshell, the size of it was not definitely changed, but dopamine was well reacted with chitosan-gold nanoshell, and it generated SERS (surface-enhanced Raman scattering), which led to a clear difference in the intensity of Raman scattering within the range of dopamine concentration (1 mM-10 mM). When Raman scattering was intensity marked on chitosan-gold nanoshell by employing a calibration curve according to dopamine concentration, a straight line whose margin of error was narrow was earned.

• Medical Lasers
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• 제8권2호
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• pp.97-100
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• 2019

Facial pores are a visible topographic feature of skin surfaces and are generally the enlarged openings of pilosebaceous follicles. Enlarged facial pores can be a significant cosmetic problem, particularly for women. Recently, gold nanoshell-mediated photothermal therapy (PTT) has been reported to be effective in treating recurrent acne. The treatment of enlarged facial pores with gold nanoshell-mediated PTT produced excellent results with no side effects. The two cases reported here demonstrate the possibility of gold nanoshell-mediated PTT as a safe and effective treatment for enlarged facial pores.

• Macromolecular Research
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• 제17권5호
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• pp.307-312
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• 2009

Core-shell hydrogel nanocomposite was fabricated by encapsulating a silica-gold nanoshell (SGNS) with poly(N-isopropylacrylamide-co-acrylic acid) (PNIPAM-co-AAc) copolymer. The oleylamine-functionalized SONS was used as a nanotemplate for the shell-layer growth of hydrogel copolymer. APS (ammonium persulfate) was used as a polymerization initiator to produce a hydrogel-encapsulated SGNS (H-SGNS). The amounts of NIPAM (N-isopropylacrylamide) monomers were optimized to reproduce the hydrogel-encapsulated SGNS. The shell-layer thickness was increased with the increase of polymerization time and no further increase in the shell-layer thickness was clearly observed over 16 h. H-SGNS exhibited the systematic changes of particle size corresponding to the variation of pH and temperature, which was originated from hydrogen-bonding interaction between PNIPAM amide groups and water, as well as electrostatic forces attributed by the ionization of carboxylic groups in acrylic acid.

• Bulletin of the Korean Chemical Society
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• 제27권9호
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• pp.1341-1345
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• 2006

An electrostatic interaction is responsible for the attachment of gold seeds of 1-3 nm onto APTMS (3-aminopropyl trimethoxysilane)-coated silica cores in the formation of gold clusters. A surface plasmon resonance and morphology of gold clusters were significantly affected by the pH of gold colloids prepared by THPC reducing agent. Gold colloids of alkaline pH induced the heterogeneous deposition of gold seeds onto the silica nanoparticles, probably due to the continuous reduction of residual gold ions during the attachment process. Gold colloids of acidic pH induced the monodisperse deposition of gold seeds, consequently leading to the formation of smooth gold layer on the silica nanoparticles surface. The gold nanoshells (core radius = 80 nm) prepared by gold colloids of pH 3.1 exhibited the more red-shift and relatively stronger intensity of plasmon absorption bands, compared with gold nanoshells prepared by alkaline gold colloids of pH 9.7.

• Bulletin of the Korean Chemical Society
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• 제30권4호
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• pp.869-872
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• 2009

Double-doped magnetic particles that incorporated magnetites into both the surface and inside the silica cores were fabricated via the sol-gel reaction of citrate-stabilized magnetites with silicon alkoxide. Double-doped magnetic particles were easily fabricated and exhibited an higher magnetism in comparison to the singledoped magnetic particles that were prepared by the erosion of surface-deposited magneties from double-doped magentic particles. Thin gold layer was formed over magnetic silica nanospheres via nanoseed-mediated growth of gold clusters. The plasmon-derived absorption bands of double-doped magnetic silica-gold nanoshells were more broadened and shifted down by ca. 20 nm as compared to those of single-doped magnetic silicagold nanoshells, which were attributed to not only the surface scattering of incident light due to relatively rough surafce morphology, but also heterogeneous permittivity of dielectric cores due to surface-deposited magnetites.

• Bulletin of the Korean Chemical Society
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• 제33권11호
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• pp.3735-3739
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• 2012

We have developed magnetically controllable gold nanoparticles by synthesizing superparamagnetic $Fe_3O_4$ core/gold shell nanoparticles. The core/shell particles have the capability of forming gold 1D chains in the presence of an external magnetic field. Here we demonstrate dynamic and reversible self-assembly of the gold 1D chain structures in an aqueous solution without any templates or physical or chemical attachment. The spatial configuration of gold chains can be arbitrarily manipulated by controlling the direction of a magnetic field. This technique can provide arbitrary manipulation of gold 1D chains for fabrication purpose. To demonstrate this capability, we present a technique for immobilization of the gold particle chains on a glass substrate.

• Korean Chemical Engineering Research
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• 제54권2호
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• pp.200-205
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• 2016

본 연구에서는 최근 많은 분야에서 응용되고 있는 형광물질인 양자점을 생명고분자인 키토산과 반응시켜 얻은 나노입자와 금속성 골드 나노입자, 그리고 실버 나노입자로 외부를 코팅하여 나노약물 전달체를 얻을 수 있었다. 키토산은 생체고분자로써 무독성이며 인체적합성 고분자이다. 양자점은 2~10 nm의 크기를 가지는 반도체성 나노입자이다. 양자점은 생명분자나 생명단백질의 비슷한 크기를 갖으며, 그 크기에 따라 알맞은 가시광선 영역의 빛을 발산할 수 있도록 조절 가능하므로, 세포 바이오 마킹, 약물전달체 등에 효과적으로 쓰일 수 있다. 따라서 키토산 나노입자 말단의 아민기와 양자점의 카르복실기가 아미드결합을 형성하여 반응하게 조절하였다. 양자점의 독성을 완화시키기 위해 코팅재료로 사용된 금속성 나노입자 중 골드나노입자는 약 5~10 nm의 크기를 가지고 있고, 인체에 무해하고 음전하를 띄어서 양전하를 띈 고분자와 쉽게 복합체를 형성할 수 있는 장점이 있다. 향균성으로 잘 알려진 실버나노입자는 약 5 nm의 크기를 가지고 있고, 은 나노입자로 코팅을 하면 미생물 감염을 미리 방지 할 수 있는 장점을 가지고 있다. 본 연구에서 만들어진 QDs-키토산-골드 & QDs-키토산-실버 나노쉘의 입자크기는 약 100 nm의 크기를 갖었으며, 목적하는 바 형광특성을 잘 보여주고 있었다. 이러한 입자들은 정전기적 상호작용에 의하여 각각 골드나노입자와 실버나노입자로 코팅되어 나노 약물전달체로 완성할 수 있었다.

• Bulletin of the Korean Chemical Society
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• 제28권6호
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• pp.909-910
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• 2007

• Journal of the Optical Society of Korea
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• 제18권3호
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• pp.274-282
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• 2014

In this study, closely spaced Au nanoparticles which are arranged in nanocluster (heptamer) configurations have been employed to design efficient plasmonic subwavelength devices to function at the telecommunication spectrum (${\lambda}$~1550 nm). Utilizing two kinds of nanoparticles, the optical properties of heptamer clusters composed of Au rod and shell particles that are oriented in triphenylene molecular fashion have been investigated numerically, and the cross-sectional profiles of the scattering and absorption of the optical power have been calculated based on a finite-difference time-domain (FDTD) method. Plasmon hybridization theory has been utilized as a theoretical approach to characterize the features and properties of the adjacent and mutual heptamer clusters. Using these given nanostructures, we designed a complex four-branch ($1{\times}4$) Y-shape splitter that is able to work at the near infrared region (NIR). This splitter divides and transmits the magnetic plasmon mode along the mutual heptamers arrays. Besides, as an important and crucial parameter, we studied the impact of arm spacing (offset distance) on the guiding and dividing of the magnetic plasmon resonance propagation and by calculating the ratio of transported power in both nanorod and nanoshell-based structures. Finally, we have presented the optimal structure, that is the four-branch Y-splitter based on shell heptamers which yields the power ratio of 23.9% at each branch, 4.4 ${\mu}m$ decaying length, and 1450 nm offset distance. These results pave the way toward the use of nanoparticles clusters in molecular fashions in designing various efficient devices that are able to be efficient at NIR.