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http://dx.doi.org/10.5012/bkcs.2013.34.1.237

Chitosan-gold Nano Composite for Dopamine Analysis using Raman Scattering  

Lim, Jae-Wook (Department of Chemical & Bio Engineering, Gachon University)
Kang, Ik-Joong (Department of Chemical & Bio Engineering, Gachon University)
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Abstract
This experiment was conducted for the purpose of developing such a sensor that can quickly sense dopamine concentration by using chitosan-gold nanoshell. Chitosan nano particles were reacted with gold nano particles so as to synthesize chitosan-gold nanoshell, and the size of the synthesized product was about 150 nm. When dopamine was reacted with chitosan-gold nanoshell, the size of it was not definitely changed, but dopamine was well reacted with chitosan-gold nanoshell, and it generated SERS (surface-enhanced Raman scattering), which led to a clear difference in the intensity of Raman scattering within the range of dopamine concentration (1 mM-10 mM). When Raman scattering was intensity marked on chitosan-gold nanoshell by employing a calibration curve according to dopamine concentration, a straight line whose margin of error was narrow was earned.
Keywords
Chitosan-gold nano composite; Dopamine sensor; SERS;
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