• Clinical and Experimental Reproductive Medicine
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• 제24권2호
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• pp.253-259
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• 1997

Objective: To investigate effects of cryoprotectant and cryopreservation on the chromosome of the human immature oocytes. Design: Intact cumulus-enclosed immature oocytes were collected from unstimulated ovaries and divided into three groups, such as no treatment as control (group 1), only 1,2-propanediol (PROH)-treated (group 2), and cryopreserved oocytes (group 3). Oocytes in group 1, 2, and survived oocytes after cryopreservation in group 3 were cultured for 48 hours. Setting: Infertility Medical Center at the CHA General Hospital, Seoul, Korea. Patients: Oocytes were obtained from Patients undergoing gynecological surgery. Main Outcome Measures: Maturation rate, abnormality in chromosomes by fluorescence in situ hybridization (FISH). Results: There was no effect of PROH only treatment on the chromosomal abnormalities in group 2 compared to control oocytes (41.4% and 31.8%, respectively). Whereas significantly increased abnormalities in chromosome (77.8%) were found in group 3. Conclusions: Human oocytes matured in vitro after cryopreservation at the germinal vesicle (GV) stage showed increased incidence of chromosomal abnormalities. These abnormalities may impair the capacity for further development of the embryos derived from frozen-thawed oocytes.

• Clinical Endoscopy
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• 제56권3호
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• pp.315-324
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• 2023

Background/Aims: Image-enhanced endoscopy can detect superficial oro-hypopharyngeal squamous cell carcinoma; however, reliable endoscopy of the pharyngeal region is challenging. Endoscopy under general anesthesia during transoral surgery occasionally reveals multiple synchronous lesions that remained undetected on preoperative endoscopy. Therefore, we aimed to determine the lesion detection capability of endoscopy under general anesthesia for superficial oro-hypopharyngeal squamous cell carcinoma. Methods: This retrospective study included 63 patients who underwent transoral surgery for superficial oropharyngeal squamous cell carcinoma between April 2005 and December 2020. The primary endpoint was to compare the lesion detection capabilities of preoperative endoscopy and endoscopy under general anesthesia. Other endpoints included the comparison of clinicopathological findings between lesions detected using preoperative endoscopy and those newly detected using endoscopy under general anesthesia. Results: Fifty-eight patients (85 lesions) were analyzed. The mean number of lesions per patient detected was 1.17 for preoperative endoscopy and 1.47 for endoscopy under general anesthesia. Endoscopy under general anesthesia helped detect more lesions than preoperative endoscopy did (p<0.001). The lesions that were newly detected on endoscopy under general anesthesia were small and characterized by few changes in color and surface ruggedness. Conclusions: Endoscopy under general anesthesia for superficial squamous cell carcinoma is helpful for detecting multiple synchronous lesions.

• 동의생리병리학회지
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• 제16권5호
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• pp.873-880
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• 2002

We study on the significance and application of the whole body form diagnosis. The results were as follows; The general form diagnosis is the method to observe the individual physiology and pathology. The phase of thinking, the current and activity of KI, the pattern of general form diagnosis have organic relations with the symptoms. The general form diagnosis is made up the principle of the imaging phase, therefore it must make synthetic union the differentiation of syndromes. The general form diagnosis of NAE GYEONG shows the typical phases and it is divided with the sight of YIN YANG and Five-Element. The general form diagnosis of SEOP GAE is practiced the theory of constitution's demonstration before the understanding of symptoms. Then JANG NAM tried the type of constitution's demonstration. The general form diagnosis of DONG MU becomes the diagnostic root of constitution's demonstration in four type constitution theory.

• 대한장애인치과학회지
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• 제13권2호
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• pp.73-79
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• 2017

The purpose of this study was to analyze the dental treatment of patients with disabilities, especially according to the frequency of general anesthesia, and to propose the improvements in oral care. The subjects of the present study were 85 patients including age, sex, medical condition, dental treatment and the number of general anesthesia. The patients were divided into regular and irregular check groups according to their follow-up patterns. These two groups were compared for the frequency of general anesthesia and the type of repeated treatment. The results showed that restorative treatment was superior in numbers under first visit of general anesthesia. And more general anesthesia was performed in the irregular recall check group compared with the regular recall check group. This survey suggest that easy access to a dental clinic and the convenience of treatment is needed. On the other hand, there is a time limit on the dental care for disabilities by the dentist. Therefore oral care training program should be simultaneously provided for parents to improve the efficiency of dental care at home. In conclusion, efforts should be made for more comprehensive and effective dental care including regular recall check and preventive home care for disabilities.

• 간호행정학회지
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• 제14권2호
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• pp.167-175
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• 2008

Purpose: To examine the changes in nurse staffing in hospitals after implementing the policy of differentiating inpatient nursing fees by staffing grades. Method: The study sample included 43 tertiary hospitals, 185 general hospitals, and 282 non-general hospitals that were operating in both 1999 and 2008. Nurse staffing grade was categorized from Grade 1 (highest) to 6 (lowest) in 1999 or Grade 7 in 2008, based on the nurse-to-bed ratio. Results: Tertiary hospitals at Grade 3 and Grade 4 accounted for 49% and 35%, respectively, in 2008, whereas 63% were Grade 6 in 1999. General hospitals at Grade 6 decreased from 87% to 48%. In non-general hospitals, little change was found in the staffing distribution, in that 92% still remained in Grade 6 or 7 in 2008. Forty tertiary hospitals (93%) and 45% of general hospitals improved their staffing grades, while only 7% of non-general hospitals did. Greater likelihood of improvement in staffing grades was found in general hospitals located in metropolitan areas or having 250 or more beds. Conclusion: Elaboration of the financial incentive system is needed to increase the policy impact on staffing improvement.

• 재활간호학회지
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• 제15권1호
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• pp.20-29
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• 2012

Purpose: The purpose of this study was to explore factors affecting uncertainty and general well-being based on Uncertainty in Illness Theory. Methods: Data were collected from 125 outpatients who had received hemodialysis. The path model among four concepts, such as period of hemodialysis, social support, uncertainty, and general well-being, was tested. Tangible support, positive social interaction, affectionate, and emotional/informational support were measured as social support. Adaptation in the model was operationalized as general well-being which consisted of anxiety, depression, positive well-being, self-control, and general health. Results: All paths were statistically significant at the level of ${\alpha}$=.05. The significant paths were the path from period of hemodialysis to uncertainty (t=-2.86), social support to uncertainty (t=-2.01), uncertainty to general wellbeing (t=-2.85), and social support to general well-being (t=3.55). Conclusion: Patients who perceived low uncertainty and high social support were likely to feel well-being. Therefore, nurses should give patients appropriate information according to their needs and have meaningful interaction with patients to reduce their uncertainty and render social support.

• 아동학회지
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• 제29권5호
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• pp.243-269
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• 2008

The role of domain-specific causal mechanism information and domain-general conditional probability in young children's causal reasoning on physics and psychology was investigated with the participation of 121 3-year-olds and 121 4-year-olds recruited from seven child care centers in Seoul, Kyonggi Province, and Busan. Children watched moving pictures on physical and psychological phenomena, and were asked to choose an appropriate cause and justify their choice. Results showed that young children's causal reasoning differed depending on domain-specific mechanism. In addition, their causal reasoning on physics and psychology differed by the developmental level of causal mechanism. The interaction of domain-specific mechanism and domain-general conditional probability influenced children's causal reasoning : evident conditional probability between domain-appropriate cause and effect helped children make more inferences based on domain-specific causal mechanism.

• Journal of applied mathematics & informatics
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• 제30권1_2호
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• pp.211-217
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• 2012

In this paper, we give the weighted Lebesgue-Radon-Nikodym theorem with respect to $p$-adic invariant integral on $\mathbb{Z}_p$.

• 수산해양교육연구
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• 제27권2호
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• pp.505-515
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• 2015

This study aimed at identifying the differences between gifted students and general students in parental attitude toward science and trust perceived by them and their science self-efficacy. To achieve this purpose, a quantitative research was carried out for elementary gifted and general students. The results were as follows. Firstly, Gifted students recognized more positively their parents' attitude toward science than general students, and both of groups perceived more positively their mothers' than fathers'. Secondly, Parents' trust by gifted students was perceived more positively than by general students, but showed no difference between fathers and mothers. Thirdly, The average of science self-efficacy for gifted students was statistically meaningfully higher than for general students.

• 혜화의학회지
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• 제20권1호
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• pp.111-117
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• 2011

Purpose: This paper is aimed to report the effects of oriental medicine on general pain after childbirth Methods: Two patients, 35 years old and 33 years old, who had a general pain after childbirth, were enrolled in this study. They received oriental medicine for several months. During the treatments, we gave them Gamikunguitang(加味芎歸湯) 2 times, each for 3 weeks. we check changes of symptoms. Results: After the oriental medicine treatments, symptoms of general pain after childbirth and other symptoms were decreased or disappeared. Conclusion: This clinical cases indicate that Gamikunguitang(加味芎歸湯) is effective in treatment of the general pain after childbirth progress and relapse of symptoms. More clinical data and studies are requested for the treatment of general pain after childbirth.