• Journal of Pharmaceutical Investigation
• /
• v.38 no.6
• /
• pp.365-372
• /
• 2008

The aim of this study was to investigate the frequency of the SNPs on MDR1 exon 12, 21 and 26 in Korean population and to analyze haplotype frequency on MDR1 exon 12, 21 and 26 in Korean population. A total of 426 healthy subjects was genotyped for MDR1, using polymerase chain reaction-based diagnostic tests. Haplotype was statistically inferred using an algorithm based on the expectation-maximization (EM). MDR1 C1236T genotyping revealed that the frequency for homozygous wild-type (C/C), heterozygous (C/T) and for homozygous mutant-type (T/T) was 20.19%, 46.48% and 33.33%, respectively. MDR1 G2677T/A genotyping revealed that the frequency for homozygous G/G, heterozygous G/T, homozygous T/T, heterozygous G/A, heterozygous T/A and for homozygous A/A type was 30.75%, 42.26%, 9.86%, 7.51 %, 7.04% and 2.58%, respectively. MDR1 C3435T genotyping revealed that the frequency for homozygous wild-type (C/C), heterozygous (C/T) and for homozygous mutant-type (T/T) was 38.73%, 50.24% and 11.03%, respectively. Twelve haplotypes were observed. Of the three major haplotypes identified (CGC, TTT and TGC), the CGC haplotype were mainly predominant in the Korean populations and accounted for 29.96% of total haplotype in Korean.

• The Journal of The Korea Institute of Intelligent Transport Systems
• /
• v.14 no.1
• /
• pp.46-56
• /
• 2015

The purpose of this study is to find out the effectiveness of drivers' satisfaction over protected and permissive left-turn (PPLT) traffic signal operation. A structural equation model was established for analyzing the effectiveness of various drivers' factors (e.g., personal characteristics, driving attitude, expectation to PPLT, etc.) on the PPLT preference based on questionnaire survey. As a result, the analysis is satisfied with the critical values, such as Q value, RMR, GIF, AGIF, and NFI. The study reveals that PPLT preference increases in case of driver who is male with long social carrier related to transportation affaire and long driving experience without traffic accident involvement. Moreover, PPLT preference increases as the expectation of PPLT to improvement of traffic safety, traffic operation, and traffic environment increases. Therefore, it is recommended that the PPLT should be preferentially operated in urban area of less traffic accidents and the promotion of PPLT be actively conducted for positive effectiveness.

• Proceedings of the Korean Institute of Surface Engineering Conference
• /
• 2001.06a
• /
• pp.73-73
• /
• 2001

Boron-containing materials have several excellent properties, such as superlnardness, insulation and non-Rinear optical property. Recently, oxynitride compounds, such as Si(ON), Ti(ON), became the promising materials applied in diffusion barrier layer and solar cell. With the expectation of obtaining the hybrid property, we have firstly grown the BON thin film by radio frequency (R.F.) plasma enhanced metalorganic chemical vapm deposition (PEMOCVD) with 100 kHz frequency and trimethyl borate precursor. The plasma source gases used in this study were Ar and $H_2$, and two kinds of nhmgen source gases, $N_2$ and <$NH_3$, were also employed. The as-grown films were characterized by XPS, IR, SEM and Knoop microlhardness tester. The relationship between the films hardness and the growth rate indicated that the hardness of the film was dependent on several factors such as nitrogen source gas, substrate temperature and film thickness due to the variation of the composition and the structure of the film. Both nitrogen and carbon content could raise the film hardness, on which nitrogen content did stronger effect than carbon. The smooth morphology and continuous structure was benefit of obtaining high hardness. The maximum hardness of BON film was about 10 GPa.

• Genomics & Informatics
• /
• v.10 no.1
• /
• pp.44-50
• /
• 2012

Pattern discovery in biological sequences (e.g., DNA sequences) is one of the most challenging tasks in computational biology and bioinformatics. So far, in most approaches, the number of occurrences is a major measure of determining whether a pattern is interesting or not. In computational biology, however, a pattern that is not frequent may still be considered very informative if its actual support frequency exceeds the prior expectation by a large margin. In this paper, we propose a new interesting measure that can provide meaningful biological information. We also propose an efficient index-based method for mining such interesting patterns. Experimental results show that our approach can find interesting patterns within an acceptable computation time.

• Electronics and Telecommunications Trends
• /
• v.31 no.4
• /
• pp.86-97
• /
• 2016

빛의 반사시간 및 산란정보를 측정하여 기상정보를 수집하던 초기 라이다 기술은 실내외 3차원 정보를 확보하는 센서 기술로 응용 영역을 확대하고 있다. 특히 최근에는 자율주행차/스마트카를 중심으로 차량/보행자의 안전과 고도화된 자율주행 성능을 위하여 차량 주변 환경에 대한 3차원 좌표를 고속으로 획득하는 라이다 기술의 중요성이 부각되고 있으며, 이에 따라 관련 기술에 대한 이해와 동향파악이 필요하다. 이에 본고에서는 차량에 적용될 수 있는 라이다 기반 3차원 영상센서 기술 전반에 대한 리뷰를 진행하고, 자율주행차/스마트카 시장에서 핵심이슈 및 기술별 대응 특징을 소개한다. 아울러 3차원 센서기술의 글로벌 경쟁상황을 기반으로 향후 차량용 라이다 기술의 발전방향을 전망해 본다.

• East Asian mathematical journal
• /
• v.24 no.1
• /
• pp.45-55
• /
• 2008

We consider an M/G/1 queue with $P^M_{\lambda}$-service policy, which is a two-stage service policy. The server starts to serve with rate 1 if a job arrives to the sever in idle state. If the workload of the system upcrosses $\lambda$, then the service rate is changed to M and this rate continues until the system is empty. It costs to change the service rate to M and maintaining the rate. When the expectation of the stationary workload is supposed to be less than a given value, we derive the optimal value of M.

• International Commerce and Information Review
• /
• v.6 no.3
• /
• pp.123-136
• /
• 2004

In recent years, although far behind, the "e-Trade (B to G)" is propelled vigorously in Japan. But the diffusion of the "e-Trade" among companies (B to B) represented by bolero.net does not meet expectation. This paper carried out the questionnaire survey to the enterprises, which adopt bolero.net and examined why the diffusion is stagnated to the measures for its future spread. As a result, the top 3 adoption factors are: (1) Transaction climate, (2) Top management support, and (3) Operational improvement. In other words, it depends that top management has the will, which adopts e-trade positively among the reliable business partners and the operational performances can improve efficiently by carrying e-trade. We would like to clarify what will be crucial to spur the diffusion in the future. Based on the findings from the result, the concrete key points to promote the spread are to be indicated as follows: (1) Improve the scores of "Cost" and "Competitive pressure" (2) Improve the institutional factor.

• The Bulletin of The Korean Astronomical Society
• /
• v.41 no.1
• /
• pp.31.3-31.3
• /
• 2016

Exploring a universe with gravitational waves (GWs) was only theoretical expectation for long time. In September 2015, the Laser Interferometer GW Observatory (LIGO) first detected GWs emitted from the collision of two stellar-mass black holes in cosmological distance (1.3 billion light years) on Earth. This confirms the existence of black-hole binary mergers, and further, opens a new field of GW astronomy. We begin our discussion with a list of important GW sources that can be detectable on Earth by large-scale laser interferometers such as LIGO. Focusing on compact objects such as neutron stars and black holes, we then discuss possible research in the context of GW astronomy. By coordinating with existing observatories, searching for electromagnetic waves or particles from astronomical objects, around the world, multi-messenger astronomy for the universe's most cataclysmic phenomena (e.g. gamma-ray bursts) will be available in the near future.

• Journal of Communications and Networks
• /
• v.7 no.1
• /
• pp.29-35
• /
• 2005

This paper deals with the problem of multiuser detection over a direct-sequence code-division multiple access (DS-CDMA) channel with incomplete channel state informations (I-CSI). We devise and assess two novel recursive detectors based on the expectation conditional maximization (ECM) algorithm and the generalized likelihood ratio (GLR) principle, respectively. Both receivers entail an affordable computational complexity. Moreover, the performance assessment, conducted via Monte Carlo techniques, shows that they achieve satisfactory performance levels and outperform linear detectors.

• Journal of Korean Institute of Industrial Engineers
• /
• v.39 no.6
• /
• pp.473-479
• /
• 2013

This paper introduces user intervention to control simulation states during the execution of a simulation for military engagements. In an engagement simulation, it covers both a discrete event system and a continuous state system. Thus a system for the engagement simulation can have numerous simulation states, because there are lots of factors to decide states of an engagement that are derived during an execution of the simulation (e. g. detection probability, moving speed, moving path, and so on). It means both a result and progression of simulations are important outputs. Configuration of an engagement simulation scenario and expectation of simulation states, though, is hindered by the number of generate-able states. In order to solve the obstacle, the engagement simulation system should be controllable by user intervention during a simulation execution. This paper is to define objects of user intervention, and to design control processes of defined objects.