• 제목/요약/키워드: functional fitness

검색결과 123건 처리시간 0.033초

Involvement of the OsMKK4-OsMPK1 Cascade and its Downstream Transcription Factor OsWRKY53 in the Wounding Response in Rice

  • Yoo, Seung Jin;Kim, Su-Hyun;Kim, Min-Jeong;Ryu, Choong-Min;Kim, Young Cheol;Cho, Baik Ho;Yang, Kwang-Yeol
    • The Plant Pathology Journal
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    • 제30권2호
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    • pp.168-177
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    • 2014
  • Plant has possessed diverse stress signals from outside and maintained its fitness. Out of such plant responses, it is well known that mitogen-activated protein kinase (MAPK) cascade plays important role in wounding and pathogen attack in most dicot plants. However, little is understood about its role in wounding response for the economically important monocot rice plant. In this study, therefore, the involvement of MAPK was investigated to understand the wounding signaling pathway in rice. The OsMPK1 was rapidly activated by wounding within 10 min, and OsMPK1 was also activated by challenge of rice blast fungus. Further analysis revealed that OsMKK4, the upstream kinase of OsMPK1, phosphorylated OsMPK1 by wounding in vivo. Furthermore, OsMPK1 directly interacted with a rice defense-related transcription factor OsWRKY53. To understand a functional link between MAPK and its target transcription factor, we showed that OsMPK1 activated by the constitutively active mutant $OsMKK4^{DD}$ phosphorylated OsWRKY53 in vitro. Taken together, components involving in the wounding signaling pathway, OsMKK4-OsMPK1-OsWRKY53, can be important players in regulating crosstalk between abiotic stress and biotic stress.

경찰특공대(SWAT) 작전복(BDU)의 기능성 향상을 위한 패턴개발 - 작전복 개발 및 착의평가를 중심으로 - (The Development of a Battle Dress Uniform Pattern Improved functionality for the Korean police SWAT units - Focused on the Development and the Fitting Evaluation of the BDU -)

  • 문연실;김선희;김은경
    • 대한가정학회지
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    • 제43권5호
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    • pp.235-248
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    • 2005
  • The objective of the study was to design a Battle Dress Uniform(BDU with improved motional flexibility, body fit, and protectiveness to cope with the special operational environment of the subjects. For this purpose, the researcher conducted a questionnaire survey on 92 male members of Special Weapon Attack Team(SWAT units in a former study, and based on the results of the survey, made the two-piece and one- piece BDU samples to overcome the identified problems and inconveniences. The sample uniforms were designed ergonomically from five aspects. Subsequentlv, the new BDU was compared with the current operational uniform in terms of outward appearance(design and fit), motional flexibility, and suitability for field activities. The samples were evaluated by 5 SWAT members as subjects and 8 graduate school students majoring in clothing and textiles as experts. According to the results, the two-piece and one-piece samples gained higher scores than the existing operational uniform in terms of outward appearance(design and fitness) and motional flexibility, and the one-piece sample was preferred with regard to fit when worn by the subjects with their full kit for field operations. That is, the one-piece sample appeared to be more suited to the special work environment of SWAT and to be more functional in terms of ease of putting on and taking off, motional flexibility, body fit and protectiveness than the current operational uniform(two-piece type).

주간보호센터 중심의 재가 치매노인을 위한 프로그램의 개발 및 효과 검증 연구 (Development and Testing of Day Care Program for Demented Elders)

  • 임영미;정복희
    • 한국보건간호학회지
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    • 제19권2호
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    • pp.371-381
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    • 2005
  • Purpose: The purpose of the study was to develop the day care program for the demented elders and to determine the effects of multiple activity therapies on the physical, emotional, cognitive, social function and physiological indicators of dementia elders in day care center. Method: A total of 13 elders with mild dementia in the data care center were participated. Manual and guideline of data care program was developed. Data care program was composed of movement/exercise, foot massage, music therapy, horticultural therapy, and art therapy. Data care program was performed by trained intervener for 32 weeks. Instruments were physical functioning such as hand grip strength., vital capacity, chiar stand test, sit and reach test, one leg standing, Berg' Balance scale, 6m Walk Velocity, stair climb, ADL, GDS-K, MMSE-K, Integrative Social Functioning Scale, cortisol, Ig A and Ig G. These were measured at the baseline, 16-week, and 32-week post-intervention by the trained nurses. Data were analyzed as Wilcoxon signed rank test. Results: For Hand grip, balance, and vital capacity, there was a significant difference between baseline and 16-week post-intervention(p<.05). For one leg standing, 6m velocity, there was a significant difference between 16-week post-intervention and 32-week post-intervention(p<.05). For Stair climb, there was a significant difference between baseline and 32-week post-intervention(p<.05). For depression and social functioning, there was no significant difference among baseline, 16-week, and 32-week post-intervention. For cognitive functioning, there was a significant difference between baseline and 32-week post intervention(p<.05). There was a significant difference of cortisol, and Ig G between baseline and 32-week post-intervention(p<.05). Conclusion: It would appear that physical fitness, functional performance, ADL, depression, social and cognitive functioning, and physiological indicator of community dwelling elders with dementia can be improved through day care program using multiple stimuli.

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Mountain Clustering 기반 퍼지 RBF 뉴럴네트워크의 동정 (Identification of Fuzzy-Radial Basis Function Neural Network Based on Mountain Clustering)

  • 최정내;오성권;김현기
    • 한국정보전자통신기술학회논문지
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    • 제1권3호
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    • pp.69-76
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    • 2008
  • 본 논문에서는 Mountain clustering 알고리즘을 이용한 Fuzzy Radial Basis Function Neural Network(FRBFNN)의 규칙 수를 자동생성 방법을 제시한다. FRBFNN은 기존 RBFNN에서 가우시안이나 타원형 형태의 특정 RBF를 사용하는 구조와 달리 클러스터의 중심값과의 거리에 기반을 둔 멤버쉽함수를 사용하여 전반부의 공간 분할 및 활성화 레벨을 결정한다. 또한 분할된 로컬영역에서의 입출력 특성을 나타내는 퍼지규칙의 후반부로서 고차 다항식을 고려하였다. 본 논문에서는 데이터의 밀집도에 기반을 두어 클러스터링을 수행하는 Mountain clustering 알고리즘을 사용하여 적합한 퍼지 규칙(클러스터)의 수와 클러스터의 중심값을 자동적으로 생성하는 방법을 제안한다. Mountain clustering으로부터 구해진 클러스터의 중심은 멤버쉽 값을 결정하는데 사용되며, Weighted Least Square Estimator (WLSE) 알고리즘을 사용하여 후반부 다항식의 계수를 추정한다. 제안된 알고리즘은 비선형 함수 모델링에 적용하여 성능의 우수성과 알고리즘의 타당성을 보인다.

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국내 여성의 애슬레저 웨어 제품구매추구 및 착용실태 조사 - 20~50대 여성을 중심으로 - (A Study on Purchasing and Wearing Status of Korean Women's Athleisure Wear Products - Focusing on Women in Their 20s to 50s -)

  • 이종규;임호선
    • 한국의류산업학회지
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    • 제23권3호
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    • pp.370-379
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    • 2021
  • This study investigated the wearing status and design preferences regarding athleisure wear, focusing on young women in their 20s and 30s and middle-aged women in their 40s and 50s participating in yoga and fitness activities. A total of 332 valid samples were used for the survey by setting the same number of samples for each age group. The results showed that young women in their 20s and 30s exhibited weight control, and middle-aged women in their 40s and 50s maintained their health in relation to exercise. Athleisure wear brands were found to prefer foreign brands over domestic brands. When purchasing athleisure wear, the foremost considerations were material functionality, fit according to body shape, and reasonable prices. The preferred athleisure wear leggings design showed that both middle-aged women and young women preferred nine-piece leggings. Women in their 20s to 50s were found to purchase and acquire information on athleisure wear online. Hence, the pattern of life is rapidly transitioning from offline to online, and the market structure of athleisure wear is gradually transitioning toward an omni-channel society with a distribution market structure that combines information technology(IT) and mobile technologies. Therefore, It is required to develop athleisure wear of various functional products that meet the trends according to the global market environment and consumer class.

복합운동이 노인여성의 낙상관련지표 및 Myokine에 미치는 효과 (Effect of Combined Exercise on Fall Injury Index and Myokine in Older Adults)

  • 박우영
    • 한국응용과학기술학회지
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    • 제36권1호
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    • pp.189-199
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    • 2019
  • 이 연구의 목적은 복합운동이 노인여성의 낙상관련 지표 및 마이오카인에 미치는 효과를 보는데 있다. 근감소증은 근력의 손실로 인해 발생하고, 기능적 상태의 감소, 활동력의 저하에 따른 낙상의 위험성이 높아지고 끝내 사망의 위험성이 높아지게 된다. 유산소운동은 대근을 이용한 리듬과 반복적인 동작으로 특징 지워지고 주로 유산소성 대사를 통한 산소를 에너지 이용으로 심폐체력, 체성분 및 심장과 호흡계 건강에 기여한다. 한편 저항운동은 근육에 스트레스를 가해 노인들의 근력관련 체력과 기능적 수행 개선에 기여한다. 근기능 및 심폐지구력 향상을 꾀하는 복합운동은 노년들의 효과적인 건강증진에 기여하는 것으로 나타내고 있다. 근육에서 분비되는 마이오카인은 운동에 중요한 요인으로 간주되고 있는데 지방세포 감소, 골격, 근육 및 인체 전반에 걸쳐 유익한 효과를 보인다.

여성 피트니스웨어 색채 분석 -2017 SS시즌을 중심으로- (Analysis of Women's Fitness Wear Colors -Focused on 2017 S/S-)

  • 김리라;주미영
    • 패션비즈니스
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    • 제23권2호
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    • pp.110-123
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    • 2019
  • This study aims to investigate the color characteristics of female fitnesswear by analyzing the status of color usage and color arrangement method of each item of female fitnesswear of sports brands. This study targeted eight global total sportswear brands. A total of 2956 colors of female sportswear were collected and analyzed from the homepage of each brand. As a result of analyzing the color of fitnesswear, first, the overall color of the fitnesswear showed high distribution centered on PB, Bk and R of low color tone, such as p and dkg. Moreover, bright tone colors were added for vitality and functional image of sports. Second, as a result of analyzing the color of each item, commonly, the PB, Bk and R had large proportions. Third, as a result of analyzing 2-color arrangements of fitnesswear, color arrangements including achromatic color had overwhelmingly higher frequency than color arrangements that had only chromatic colors. This shows that the color arrangement using achromatic color is important and has a higher preference. Fourth, as a result of extracting the representative color arrangement as color chip and comparing, the 2-color arrangement of female fitnesswear had the characteristics of the color arrangement of large area main color and small amounts of emphasized color centered on achromatic colors of Bk and W. This study is meaningful that it can be utilized as basic data for color planning of fitnesswear brands by subdividing female fitnesswear into 4 items and analyzing the color-tone and arrangement.

Harnessing the Power of IL-7 to Boost T Cell Immunity in Experimental and Clinical Immunotherapies

  • Jung-Hyun Park;Seung-Woo Lee;Donghoon Choi;Changhyung Lee;Young Chul Sung
    • IMMUNE NETWORK
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    • 제24권1호
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    • pp.9.1-9.21
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    • 2024
  • The cytokine IL-7 plays critical and nonredundant roles in T cell immunity so that the abundance and availability of IL-7 act as key regulatory mechanisms in T cell immunity. Importantly, IL-7 is not produced by T cells themselves but primarily by non-lymphoid lineage stromal cells and epithelial cells that are limited in their numbers. Thus, T cells depend on cell extrinsic IL-7, and the amount of in vivo IL-7 is considered a major factor in maximizing and maintaining the number of T cells in peripheral tissues. Moreover, IL-7 provides metabolic cues and promotes the survival of both naïve and memory T cells. Thus, IL-7 is also essential for the functional fitness of T cells. In this regard, there has been an extensive effort trying to increase the protein abundance of IL-7 in vivo, with the aim to augment T cell immunity and harness T cell functions in anti-tumor responses. Such approaches started under experimental animal models, but they recently culminated into clinical studies, with striking effects in re-establishing T cell immunity in immunocompromised patients, as well as boosting anti-tumor effects. Depending on the design, glycosylation, and the structure of recombinantly engineered IL-7 proteins and their mimetics, recombinant IL-7 molecules have shown dramatic differences in their stability, efficacy, cellular effects, and overall immune functions. The current review is aimed to summarize the past and present efforts in the field that led to clinical trials, and to highlight the therapeutical significance of IL-7 biology as a master regulator of T cell immunity.

해안 가로의 지속가능성 향상을 위한 가로 시설물 연구 - 제주도 해수욕장 주변 가로시설물을 중심으로 - (A Study on the Street Facilities for the Sustainability Improvement of the Coastal Street - Focused on the Street Facilities around Jeju Island Beach -)

  • 김자경
    • 한국실내디자인학회논문집
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    • 제26권4호
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    • pp.42-56
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    • 2017
  • In Korea, which has three sides of the sea, various waterfront spaces are being developed and developed along with various coastal landscapes. However, there are a lot of cases that do not consider the regional characteristic of the coast or the characteristic of the coastal landscape. In many cases, the street facilities cause the landscape degradation and the use inconvenience because of incongruity with the scenery, aging and lax management. Therefore, it is necessary to reflect the specificity of the coastal landscape in planning and directing the street facilities, harmonizing with the surrounding natural environment, and consideration of sustainability. However, there is no research or planning index for sustainable street facilities considering the coastal characteristics. Therefore, this study suggests plan elements to improve the sustainability of the street facilities on the shore and proposes them as basic plan elements, and suggests what kind of improvements should be made to improve the sustainability of coastal facilities in Korea. Based on the plan elements derived from the plan, we checked the problems and complementary points of coastal street facilities in Korea by analyzing the current status of the street facilities around the Jeju Island beach from a sustainable point of view, and suggested plan indicators that should be supplemented to improve sustainability. We surveyed the street facilities such as walkway blocks, benches, pagoda, drinking fountain, trash cans, bicycle shelters, fences, guide maps, streetlights, and shower rooms in 10 beaches in Jeju Island. This study analyzed the sustainability characteristics of the each factor of these facilities by surveying the reflectivity of the 23 plan indicators from the six aspects derived from the sustainability planning factor as conformity, partial reflection, non - reflection, and nonconformity. The results of the analysis showed that the functional aspect was the highest with 68.3%, the material aspect (53%), the landscape aspect (22.3%), the productive aspect (14.7%) and the morphological aspect (12.2%), and maintenance / management (10.6%). In addition, the facilities with the lowest fitness in each aspect are bicycle shelter in landscape aspect, bicycle storage box and trash can in form aspect, shower room in material aspect, trash can in functional aspect, showroom, guide maps and drinking fountain in product aspect, showroom In maintenance aspect. In order to improve the sustainability of coastal facilities in the future, it is necessary to complement the administrative and landscape aspects. In coastal facilities, it is necessary to consider the sustainability planning index, especially for showers, taking into account the specificity of beaches. Consideration should be given to various aspects of sustainability for bike shelters and trash facilities. Through this study, we have proposed the plan elements to systematize, supplement, and improve the planning index for sustainability improvement in coastal facilities planning.

아키텍쳐 기반 소프트웨어 개발을 지원하는 효과적인 소프트웨어 아키텍쳐 평가 방법 (An Approach to Effective Software Architecture Evaluation in Architecture-Based Software Development)

  • 최희석;염근혁
    • 한국정보과학회논문지:소프트웨어및응용
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    • 제29권5호
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    • pp.295-310
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    • 2002
  • 소프트웨어 아키텍쳐는 소프트웨어 개발에 참여하는 사람들간의 원활한 의사 소통과 시스템 설계 결정에 대한 합리적 판단을 가능하게 하는 상위 수준의 시스템 추상화이다. 이러한 소프트웨어 아키텍쳐에 대한 평가는 소프트웨어에 요구되는 품질을 소프트웨어 개발 전에 미리 예측하거나, 고품질 소프트웨어를 개발하는대 적합한 아키텍쳐의 선택 및 향상을 가능하게 한다. 그러나 현재의 아키텍쳐 평가 방법은 아키텍쳐 평가의 초기 입력물에 대한 정의가 미흡하고, 평가 과정이 주관적인 프로세스에 많이 의존하거나 흑은 체계적인 프로세스를 정의하고 있지 않다. 뿐만 아니라 아키텍쳐 평가 정보들의 표현에 대한 고려가 부족하다. 본 논문에서 제안하는 방법은 아키텍쳐 평가의 주요 입력물인 요구사항을 기능적 요구사항과 비기능적 요구사항으로 분리하여 다루고, 소프트웨어 아키텍쳐는 UML을 이용한 "4+1"뷰 아키텍쳐 모델을 바탕으로 명확하게 정의한다. 이를 통하여 아키텍쳐 평가의 목표 및 평가 범위, 평가 대상을 분명하게 결정한다. 그리고 아키텍쳐 평가의 중요 정보들인 부분 설계, 설계 결정, 근거 데이타, 품질 등의 정보를 단계적으로 결정하기 위한 체계적이고 객관적인 프로세스를 제시한다. 또한 평가 결과에 있어서는 아키텍쳐 평가 과정에서 결정된 정보들을 구조화된 형태로 나타냄으로써 품질 예측 및 아키텍쳐의 향상과 선택이 가능하도록 돕는다.