• 한국주거학회논문집
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• 제17권2호
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• pp.77-85
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• 2006

This study aims to propose the comprehensive evaluation of performance multi-family housing. Most of the existing studies for the reproduction have evaluated by the safety of structure. Therefore those pass over the functional factors which is important for the evaluation of residential qualities. This study represents that the reproduction renovation should not be secured the safety of structure but established the quality of lift. And questionnaire asking expert's opinion also supplemented. As a result, the item for examination and the weight for evaluation are suggested in functional deterioration. The results of this study are summarized as follows: 1. Existent redevelopment criteria are not appropriate to decide the environmental comfort, the vital function of housing and the residential management finance. 2. The future criteria have to evaluate the existing environmental comfort, be reconstructed to put first general deterioration. 3. Evaluation elements was extracted throughout the document research, evaluation elements analysis system was separated in residential area, suburb of dwellings, community, and housing complexity environmental assesment, 4. Each category of influence ratio was extracted to assess total deterioration throughout the expert question survey. 5. Each category analysed (1) $0{\sim}30%$: function is good (unnecessary to improve) (2) $31{\sim}40%$: average (necessary of partial improvement) (3) $41{\sim}59%$: bad (necessary of total improvement) (4) $60{\sim}100%$: the worst (unable to improve throughout the repair)

• International Journal of Human Ecology
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• 제4권2호
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• pp.89-100
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• 2003

This paper identifies trends in research methodology due to globalization. Context in both research and in practice and forms the key perspective for modern methodology and theory. Ecological perspectives are a necessary condition for quality global research. Human ecology researchers must advance the role of interdisciplinary and inter-functional perspectives and be open to collaborative relationships. These researchers must work in teams across disciplinary and functional boundaries. The paper discusses directions for research within the context of trends at U.S. federal agencies with applications to globalization and family life. Trends include： (a) use of diverse but rigorous methodologies； (b) recognition of the research-practice-research feedback loop；(c) primacy of context and diverse sampling; and (d) connections of research to problem solving. The terms promoted recently such as ″relationships″, ″diversity″ or ″problem-based″ are ingrained in human ecology. Key aspects for research in the next decade will be： (a) seeking diversity in sampling； (b) seeking colleagues with different perspectives； (c) incorporating meta-analysis into our work； (d) seeking meaningful results； (e) utilizing varieties of research methodologies to address our problems； and (0 understanding that practice must continually change as a function of research.

• 대한수학회보
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• 제55권4호
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• pp.1065-1092
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• 2018

This manuscript is involved with a category of second-order impulsive functional integro-differential equations with nonlocal conditions in Banach spaces. Sufficient conditions for existence and approximate controllability of mild solutions are acquired by making use of the theory of cosine family, Banach contraction principle and Leray-Schauder nonlinear alternative fixed point theorem. An illustration is additionally furnished to prove the attained principles.

• 대한수학회지
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• 제54권5호
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• pp.1605-1621
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• 2017

The purpose of this paper is to construct a new family of the special numbers which are related to the Fubini type numbers and the other well-known special numbers such as the Apostol-Bernoulli numbers, the Frobenius-Euler numbers and the Stirling numbers. We investigate some fundamental properties of these numbers and polynomials. By using generating functions and their functional equations, we derive various formulas and relations related to these numbers and polynomials. In order to compute the values of these numbers and polynomials, we give their recurrence relations. We give combinatorial sums including the Fubini type numbers and the others. Moreover, we give remarks and observation on these numbers and polynomials.

• 가정과삶의질연구
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• 제28권2호
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• pp.63-76
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• 2010

A law facilitating a family-friendly social environment was legislated in December 2007. According to the law, projects for facilitating a family-friendly social environment consisted of a family-friendly working environment, a community environment, and the promotion of a family-friendly culture. There has been much progress in developing a family-friendly working environment through projects such as those advocating for flexible work hours, an employee support system, and child care and a family care support system. However, in terms of a family-friendly community environment project, there was no noticeable advancement. Hence, this study was conducted to find ways to vitalize the family-friendly village project in terms of the family-friendly community environment project. The major findings of this study were as follows: A family-friendly village could be structured on the three axes of time, space, and relation. The model of the family-friendly village project consists of the following three steps: motivation, systematization, and participating & practicing. In the motivation step, integration, community, and sustainability were needed as basic ideologies for a family-friendly village. In the systematization step, providing systematic educational systems for residents taking on leadership and activist roles was stressed. In the participating & practicing step, many ways to facilitate residents' social relationships were suggested: starting the project from matters of common interests, making the resolution of families' problems a communal task of the residents, accepting the opinions of various groups associated with the matter, and taking a differentiated project process according to the geographic, socio-economic, and demographic characteristics of the groups. It is strongly suggested that the family-friendly village should be taken as a common functional scheme in everyone of eight livable village models because a key factor in a family-friendly village, family care, serves an essential function in any livable village model.

• BMB Reports
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• 제48권2호
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• pp.81-90
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• 2015

p73 is a structural and functional homologue of the p53 tumor suppressor protein. Like p53, p73 induces apoptosis and cell cycle arrest and transactivates p53-responsive genes, conferring its tumor suppressive activity. In addition, p73 has unique roles in neuronal development and differentiation. The importance of p73-induced apoptosis lies in its capability to substitute the pro-apoptotic activity of p53 in various human cancer cells in which p53 is mutated or inactive. Despite the great importance of p73-induced apoptosis in cancer therapy, little is known about the molecular basis of p73-induced apoptosis. In this review, we discuss the p73 structures reported to date, detailed structural comparisons between p73 and p53, and current understanding of the transcription-dependent and -independent mechanisms of p73-induced apoptosis.

• 비만대사연구학술지
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• 제1권2호
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• pp.59-65
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• 2022

Obesity is a serious health concern, which has been linked to an increased risk for cardiovascular diseases and some cancers. The traditional obesity control program is expensive. Moreover, it is difficult to maintain a healthy body weight as well as reduce body fat. The long-term use of effective and tolerable medication is carefully recommended to control body weight. In addition to obesity control medications, health functional foods, related to body weight control, have become popular in the commercial market. Known mechanisms include lipolysis, appetite control, inflammation reduction, and lean body mass maintenance. Previous clinical trials have documented the efficacy of some health functional foods; however, there are limitations. Studies on the potential roles and efficacy of some health functional foods, including caffeine, green tea, protein supplement, probiotics, and arginine, were reviewed. More large-scale and randomized placebo-controlled trials should be conducted eventually.

• Human Ecology Research
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• 제58권1호
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• pp.43-60
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• 2020

The literature on parent-child relationships in young adulthood lacks a systemic approach that considers the multifaceted nature of intergenerational relationships. In this paper, we identify the latent profiles of young Korean adults' relationships with their parents based on the six dimensions of intergenerational solidarity (structural, associational, affectual, consensual, functional, and normative solidarity) as indicators. We considered solidarity for the mother and the father separately for structural, associational, affectual, and consensual dimensions. In terms of functional and normative solidarity, we measured both upstream and downstream intergenerational support. The sample included 1,015 young adults who were 19-34 years old, never married, not in secondary school, and had both parents living. The latent profile analysis revealed four profiles: (a) independent but intimate (22.7%), (b) coresident, outwardly intimate (32.4%), (c) detached from father (6.7%), and (d) coresident, intimate (38.2%). The factors that predicted each profile included the young adults' education, income, subjective socioeconomic status, and experiencing the features of emerging adulthood along with the parents' marital status, father's employment, and overparenting. The "coresident, intimate" group reported significantly higher levels of life satisfaction and fewer depressive symptoms compared to the other three groups. The lowest levels of psychological adjustment were found in the "coresident, outwardly intimate" group and "detached from father" group.

• Genomics & Informatics
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• 제20권2호
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• pp.19.1-19.15
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• 2022

Alfalfa (Medicago sativa) is an important food and feed crop which rich in mineral sources. The WUSCHEL-related homeobox (WOX) gene family plays important roles in plant development and identification of putative gene families, their structure, and potential functions is a primary step for not only understanding the genetic mechanisms behind various biological process but also for genetic improvement. A variety of computational tools, including MAFFT, HMMER, hidden Markov models, Pfam, SMART, MEGA, ProtTest, BLASTn, and BRAD, among others, were used. We identified 34 MsWOX genes based on a systematic analysis of the alfalfa plant genome spread in eight chromosomes. This is an expansion of the gene family which we attribute to observed chromosomal duplications. Sequence alignment analysis revealed 61 conserved proteins containing a homeodomain. Phylogenetic study sung reveal five evolutionary clades with 15 motif distributions. Gene structure analysis reveals various exon, intron, and untranslated structures which are consistent in genes from similar clades. Functional analysis prediction of promoter regions reveals various transcription binding sites containing key growth, development, and stress-responsive transcription factor families such as MYB, ERF, AP2, and NAC which are spread across the genes. Most of the genes are predicted to be in the nucleus. Also, there are duplication events in some genes which explain the expansion of the family. The present research provides a clue on the potential roles of MsWOX family genes that will be useful for further understanding their functional roles in alfalfa plants.

• Genomics & Informatics
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• 제8권4호
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• pp.201-205
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• 2010

The H1 histone family, member N, testis-specific (H1FNT) is exclusively expressed in the testis, and had its possible role for sperm chromatin formation. The purpose of this study is to investigate any genetic association of H1FNT gene with male infertility, especially at the promoter region. We examined the promoter single nucleotide polymorphisms (SNP) of H1FNT gene which is located within transcription factor binding site for its association with male infertility. The statistical analysis showed that the -1129A>T polymorphism was present at a statistically significance in male infertility (p=0.0059 and 0.0349 for hetero and risk type, respectively). The dual-luciferase promoter assay was performed to examine the polymorphic effect of this promoter SNP by the cloning of promoter region (1700bp fragment) into pGL3-basic vector. In our plasmid based reporter system, there is no big difference between wild and risk type. In conclusion, H1FNT -1129A>T promoter SNP is statistically significant with male infertility, especially with subfertile (non-azoospermia) group. Further analysis of its functional polymorphic effect in vivo may provide the biological significance of testis-specific histone with spermatogenesis.