• Title/Summary/Keyword: free-year system

검색결과 197건 처리시간 0.024초

Clinical and biochemical outcomes of men undergoing radical prostatectomy or radiation therapy for localized prostate cancer

  • Schreiber, David;Rineer, Justin;Weiss, Jeffrey P.;Safdieh, Joseph;Weiner, Joseph;Rotman, Marvin;Schwartz, David
    • Radiation Oncology Journal
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    • 제33권1호
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    • pp.21-28
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    • 2015
  • Purpose: We analyzed outcomes of patients with prostate cancer undergoing either radical retropubic prostatectomy (RRP) +/- salvage radiation or definitive radiation therapy (RT) +/- androgen deprivation. Materials and Methods: From 2003-2010 there were 251 patients who underwent RRP and 469 patients who received RT (${\geq}7,560cGy$) for prostate cancer. Kaplan-Meier analysis was performed with the log-rank test to compare biochemical control (bCR), distant metastatic-free survival (DMPFS), and prostate cancer-specific survival (PCSS) between the two groups. Results: The median follow-up was 70 months and 61.3% of the men were African American. For low risk disease the 6-year bCR were 90.3% for RT and 85.6% for RRP (p = 0.23) and the 6-year post-salvage bCR were 90.3% vs. 90.9%, respectively (p = 0.84). For intermediate risk disease the 6-year bCR were 82.6% for RT and 59.7% for RRP (p < 0.001) and 82.6% vs. 74.0%, respectively, after including those salvaged with RT (p = 0.06). For high risk disease, the 6-year bCR were 67.4% for RT and 41.3% for RRP (p < 0.001) and after including those salvaged with RT was 67.4% vs. 43.1%, respectively (p < 0.001). However, there were no significant differences between the two groups in regards to DMPFS or PCSS. Conclusion: Treatment approaches utilizing RRP +/- salvage radiation or RT +/- androgen deprivation yielded equivalent DMPFS and PCSS outcomes. Biochemical control rates, using their respective definitions, appeared equivalent or better in those who received treatment with RT.

Technology of Air-Conditioning System by Ocean Thermal Energy near Busan Coast (부산지역 해수온도차이용 냉난방기술)

  • Oh, Cheol;Kim, Meong-Whan;Lim, Tae-Woo;Choi, Young-Do
    • Proceedings of the SAREK Conference
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    • 대한설비공학회 2009년도 하계학술발표대회 논문집
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    • pp.350-355
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    • 2009
  • Air-conditioning system by ocean thermal energy has been developed in the areas of Europe, North America and Japan because there are abundant amount of thermal energy potential in the ocean and permanent free use for the thermal energy using the air-conditioning system. In the case of domestic ocean thermal energy resource, ocean thermal energy potential exists about 27,155Tcal/year and totally 20,285Tcal/year of possible thermal energy use by heat pump, which are reported from the survey of the 7 domestic near shore cities. Present study is aimed to survey the current development status of domestic and overseas air-conditioning system by ocean thermal energy, especially, for the air-conditioning facility technologies using sea water.

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A study on the treatment of water discharge from the water treatment plant using end-free submerged membrane - Causes and solution of membrane fouling - (자유 말단형 침지식 분리막을 이용한 정수장 배출수 처리 연구 - 막오염 발생 원인과 해결 방안 -)

  • Kim, Jun-Hyun;Jang, Jung-Woo;Kim, Jin-Ho;Park, Kwang-Duck
    • Journal of Korean Society of Water and Wastewater
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    • 제34권2호
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    • pp.93-104
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    • 2020
  • As water resources are limited and legal regulations are strengthened, there is a growing need to reuse residuals in WTP(Water Treatment Plant). In this study, membrane filtration system was constructed and its operation method was studied for water quality stabilization and reuse of WTP residuals. The operation parameters were stable for 1 year and 6 months. Membrane fouling was identified as particulate pollution (activated carbon) and inorganic pollution (manganese). The membrane system was operated steadily with raw water of high concentration SS(Suspended solid) containing activated carbon because membrane fouling was reduced by the effect of End-Free type. In the case of inorganic contamination, dissolved manganese eluted by chemicals and acted as a membrane fouling source, and the operating conditions for minimizing membrane fouling. were confirmed by newly developing application methods and types of cleaning chemicals. Based on the results, design parameters for reducing manganese membrane fouling were derived.

Circulating Lymphocytes as Predictors of Sensitivity to Preoperative Chemoradiotherapy in Rectal Cancer Cases

  • Dou, Xue;Wang, Ren-Ben;Yan, Hong-Jiang;Jiang, Shu-Mei;Meng, Xiang-Jiao;Zhu, Kun-Li;Xu, Xiao-Qing;Mu, Dian-Bin
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권6호
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    • pp.3881-3885
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    • 2013
  • Objective: The objective of this study was to identify clinical predictive factors for tumor response after neoadjuvant chemoradiotherapy (nCRT) in locally advanced rectal cancer (LARC). Methods: All factors were evaluated in 88 patients with LARC treated with nCRT. After a long period of 4-8 weeks of chemoradiotherapy, 3 patients achieved clinical complete response (cCR) and thus aggressive surgery was avoided, and the remaining 85 patients underwent a curative-intent operation. The response to nCRT was evaluated by tumor regression grade (TRG) system. Results: There were 32 patients (36.4%) with good tumor regression (TRG 3-4) and 56 (63.6%) with poor tumor regression (TRG 0-2). Lymphocyte counts and ratios were higher in good response cases (P=0.01, 0.03, respectively) while neutrophil ratios and N/L ratios were higher in poor response cases (P=0.04, 0.02, respectively). High lymphocyte ratios before nCRT and good tumor regression (TRG3-4) were significantly associated with improved 5-year disease-free survival (P<0.05). Pretreatment nodal status was also significantly associated with 5-year disease-free survival and 5-year overall survival (P<0.05). Multivariate analysis confirmed that the pretreatment lymphocyte ratio and lymph nodal status were independent prognostic factors. Conclusion: Our study suggested that LARC patients with high lymphocyte ratios before nCRT would have good tumor response and high 5-year DFS and OS.

A Study on Satisfaction for Free Food Service of Elementary and Middle School Parents in Chungnam Province (충남 학부모의 무상학교급식 만족도와 이에 영향을 미치는 요인에 대한 연구)

  • Yang, Sung-Bum
    • The Korean Journal of Food And Nutrition
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    • 제30권2호
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    • pp.356-362
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    • 2017
  • The aims of this study was to investigate the satisfactions with school food service and its influencing factors for elementary and middle school parents. We surveyed parents regarding their concerns about food ingredients and dietary life, perceptions of free school food service, the necessity of food supply systems such as school food service centers, and the satisfaction about the quality and management of school food services. Compared to the last year, concerns about food ingredients and dietary life as well as perceptions about free school food services decreased. The reported necessity of supply system such as school food service centers and co-purchasing was lower than in 2015. The satisfaction about the school food service decreased, compared to 2015. More individuals had higher concerns about local food and stated the necessity for school food supply systems, as well as a higher satisfaction about the quality and management of school food services. In conclusion, it is important to emphasize characteristics of school food services such as co-purchasing local foods.

Commercial Production of Seed Garlic by Tissue Culture Technique (조직배양에 의한 씨마늘의 상업적 생산)

  • NAM Sang-Il;PARK Ju-Hyun;CHOI Jong-In;KWON Ki-Seok;UHM Jeong-Sik
    • Proceedings of the Korean Society of Plant Biotechnology Conference
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    • 한국식물생명공학회 2002년도 추계학술대회
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    • pp.33-40
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    • 2002
  • We, Tong Yang Moolsan Co. Ltd. (TYM) set up the mass-production system for virus-free seed garlic via tissue culture technique. TYM's tissue culture technique is called as 'Multiple shoot propagation technique'. This technique can lead mass propagation of genetically homogeneous seed garlic in a short period because of its highly proliferation rate of in vitro shoots ($15^{10}$ /year). TYM researchers applied the technique to some selected garlic cultivars with superior characteristics and carried out field test of productivity in the inside and outside of the country for several years. According to the yearly results of field test with virus-free seed garlic, we ascertained that virus-free seed garlic can produce the highly yield increase (max. above $50\%$) and also can enhance the product quality. Consequently, we estimated that TYM's seed garlic will contribute to farmers with increase of income and can elevate the national position of garlic market in the world for its competitive power of technical and production cost.

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Korea's Free Economic Zone as an Economic Development Strategy and Operational System (경제발전전략으로서 한국의 경제자유구역과 운영체계에 관한 연구)

  • Koh, Eui-Hyeon
    • Journal of Distribution Science
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    • 제12권9호
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    • pp.113-123
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    • 2014
  • Purpose - After Korea's Free Economic Zone (FEZ) system was launched in 2003, there have been many debates about upgrading it and its support systems. However, as of 2013, there were insufficient results. Further, upon the designation of the East Coast and Chungbuk as official FEZs from February 4, 2013 by the 56th the Commission, there is a concern that many people are in the area designated as FEZ 8. This study investigates Korea's new FEZ system as part of Korea's primary new economic development policy in the 21st century. Therefore, this study examines views on the weaknesses of the past ten years of FEZs so that Korea can expand its FEZ system. Research design, data, and methodology -Many countries have considered the FEZ as an economic special zone. By reviewing previous research models, this study provides an update using recent data and materials, until 2013, from the Center of Free Economic Zones. In previous studies, the lack of support systems was attributed to proposals to ensure operational autonomy and differentiation of each FEZ; however, the main cause cannot be solved through regulatory issues, as difficulties caused by the operational system are responsible for the problems. We wish to analyze the FEZ, specifically the operational system; this is the main issue of this study. Results - After the first FEZs were established, it became necessary to have basic plans, as investment results in 2013 compared to the same period this year led to lower earnings in the first half of 2014. We propose an improvement of the operational system because in the free economic zones, the operational system is the root cause of the underlying problem. The results of this research are as follows. The weak management of the FEZ system is influenced by weak investment, delayed development, foreigners' living facilities, benefits of foreign investments, the control tower's policy making decision process, quickness of the process of satisfying legal requirements, and support For the independence of FEZs. Conclusion - Local governments do not have legal rights over FEZ deregulation and investment industries. This study suggests that the local government should have more independence from the central government. Moreover, independent management committees are more effective for ensuring public rights, better employee responsibilities, and better-qualified personnel. The FEZ committee struggles to effectively manage the locations of FEZs, foreign investments, and related facilities under the control of the Ministry of Trade, Industry and Energy. Thus, the FEZ committee should be under either the Prime Minister's office or the Presidential committee, to control and effectively coordinate between the local and central governments. If the problem clearly applies to the operational system in 2013, it is necessary to provide materials and methods so that the results of the first half of 2014 can be computed despite the data limits and lack of resources, and the data can be analyzed in a more diachronic thesis.

Long-term tolerance and outcomes for dose escalation in early salvage post-prostatectomy radiation therapy

  • Safdieh, Joseph J.;Schwartz, David;Weiner, Joseph;Weiss, Jeffrey P.;Rineer, Justin;Madeb, Isaac;Rotman, Marvin;Schreiber, David
    • Radiation Oncology Journal
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    • 제32권3호
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    • pp.179-186
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    • 2014
  • Purpose: To study the long-term outcomes and tolerance in our patients who received dose escalated radiotherapy in the early salvage post-prostatectomy setting. Materials and Methods: The medical records of 54 consecutive patients who underwent radical prostatectomy subsequently followed by salvage radiation therapy (SRT) to the prostate bed between 2003-2010 were analyzed. Patients included were required to have a pre-radiation prostate specific antigen level (PSA) of 2 ng/mL or less. The median SRT dose was 70.2 Gy. Biochemical failure after salvage radiation was defined as a PSA level >0.2 ng/mL. Biochemical control and survival endpoints were analyzed using the Kaplan-Meier method. Univariate and multivariate Cox regression analysis were used to identify the potential impact of confounding factors on outcomes. Results: The median pre-SRT PSA was 0.45 ng/mL and the median follow-up time was 71 months. The 4- and 7-year actuarial biochemical control rates were 75.7% and 63.2%, respectively. The actuarial 4- and 7-year distant metastasis-free survival was 93.7% and 87.0%, respectively, and the actuarial 7-year prostate cancer specific survival was 94.9%. Grade 3 late genitourinary toxicity developed in 14 patients (25.9%), while grade 4 late genitourinary toxicity developed in 2 patients (3.7%). Grade 3 late gastrointestinal toxicity developed in 1 patient (1.9%), and grade 4 late gastrointestinal toxicity developed in 1 patient (1.9%). Conclusion: In this series with long-term follow-up, early SRT provided outcomes and toxicity profiles similar to those reported from the three major randomized trials studying adjuvant radiation therapy.

Design and Implementation of Free Choice Activity Management System based on Smart Education (스마트교육 기반 자유선택활동 운영시스템 설계 및 구현)

  • Kim, Kyung-Min;Park, Hyun-Sook
    • The Journal of Korean Association of Computer Education
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    • 제22권3호
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    • pp.123-133
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    • 2019
  • The purpose of this study is to establish Smart Education Environment for children's personalized learning based on the data are accumulated by Smart Device which is one of element on Smart Education. In this study, we propose the operational improvement plan for the free choice activity in the 5-year-old kindergarten and also implement the Free Choice Activity(FCA) management system for children to select and to evaluate the play plans for themselves. Children participating in this study have fun the whole time for the process of self-planning, the playing activities and the self-assessment of playing. As a result, it is confirmed that children participate actively in decision-making of interesting areas through the smart device than the traditional education environment before. A single teacher using FCA management system with smart device in this study can get useful information without difficulty of individual child's interests, learning and the statistics of children in the classroom.

A Theoretical Study on the Toyota Production System and Practical Example (도요타 생산방식(TPS)의 이론과 실제)

  • Lim, Jae-Hwa;Mok, Jin-Hwan
    • 한국산학경영학회:학술대회논문집
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    • 한국산학경영학회 2006년도 춘계학술발표대회 발표논문집
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    • pp.171-190
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    • 2006
  • Toyota 2005 annual report said Toyota has six consecutive fiscal year positive revenues and record breaking revenues during recent four consecutive years. Net profit is 11% grower than last year. (\11,000,000,000,000). In the spotlight they have record breaking net profit every year, their strongest point is their unique production system which come up with MUDA(waste) free and ongoing improvement activity. Their basic production philosophy is value added through improve production efficiency which can be possible by eliminating MUDA(waste). This basic philosophy's key points are "Just in Time" and "Automation with human". Recently, Korean manufacturing companies and service companies have a growing interest in Toyota Production System. They try to find ways for appling Toyota system to their companies. Through observing Toyota production theory, understand Toyota Production System, Through studying practical application in industrial fields, examine application possibility for Korean industry and more detailed researches are required.

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