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Ginseng Prevents DNA-adduct Formation in Rat Hepatocytes in vitro Treated with DMBA

  • Kumar, Ashok
    • Proceedings of the Ginseng society Conference
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    • 1998.06a
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    • pp.263-269
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    • 1998
  • It is an established fact that most of the carcinogens implicate bay-region diol epoxides as the ultimate carcinogenic metabolites. These electrophiles react with nucleophilic sites in the cells to form abducts. It is the formation of carcinogenic-DNA adducts that is thought to initiate carcinogenesis. In our previous study we have reported chemopreventive property of Ginseng on 7,12-dimethylbenz (a)anthracene (DMBA) induced skin papillomagenesis in male Swiss albino mice. In this study we have examined the effect on formation of DMBA-DNA adducts in rat hepatocytes pretreated with ginseng. Primary cultures of rat hepatocytes were used. The cells wets treated with ginseng for 24 hrs and then with DMBA (iOn) for 18 hrs. Cells were then harvested, their DNA was isolated and analyzed by P)2 labelling. A significant reduction in the levels of DMBA-DNA adduces (adducts/108 nucleotides) was observed in all cultures pretreated with ginseng. The viability of cells was not affected by pre-treatment with ginseng. Our finding suggests that ginseng block or suppresses the events associated with chemical carcinogenesis by inhibiting metabolic activation of the carcinogens.

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Design of redundancy interface between TCMS and ATC system, and brake control of free-axle system (TCMS와 ATC장치간 인터페이스 이중계 구현 및 무축제동 제어방안)

  • Hong Gu-sun;Han Shin;Han Jeong-soo
    • Proceedings of the KSR Conference
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    • 2004.10a
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    • pp.1461-1466
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    • 2004
  • Recently Domestic EMU's on board signal systems are gradually changed form Cab signal(Fix Block) to Distance-to-go. Interfaces with on board signal system, TCMS Redundancy structure is mainly required. This paper suggest Manaul/Automatic Driving based on TCMS-ATC interface and design of backup system which is operated by Stan-by Computer when one of it's Local Interface Unit(LIU) is out of oder. For the purpose of Precision Train Stop, Distance-to-go signal system require accuracy speed. Free-axle structure is required for this system This paper suggest Free-axle braking system that lack of brake-force is compensated by the distributed brake-force using TCMS. And one of braking system has out of order, compensation of brake-force for Free-axle system. Then we prove our design to Complete Car Test

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Digital Hologram Coding Technique using Block Matching of Localized Region and MCTF (로컬영역의 정합기법 및 MCTF를 이용한 디지털 홀로그램 부호화 기술)

  • Seo, Young-Ho;Choi, Hyun-Jun;Kim, Dong-Wook
    • Proceedings of the IEEK Conference
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    • 2006.06a
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    • pp.415-416
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    • 2006
  • In this paper, we proposed a new coding technique of digital hologram video using 3D scanning method and video compression technique. The proposed coding consists of capturing a digital hologram to separate into RGB color space components, localization by segmenting the fringe pattern, frequency transform using $M{\tiems}N$ (segment size) 2D DCT (2 Dimensional Discrete Cosine Transform) for extracting redundancy, 3D scan of segment to form a video sequence, motion compensated temporal filtering (MCTF) and modified video coding which uses H.264/AVC.

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Development of a Real Time Control System Using Simulink/RTW (Simulink/RTW를 이용한 실시간 제어시스템 개발)

  • Kang, Moon-Ho;Jeong, Dae-Yeon
    • Proceedings of the KIEE Conference
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    • 2000.07d
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    • pp.2392-2394
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    • 2000
  • In this research a real time control system was developed without program codings during control system designing procedures. On the Simulink window control system is designed in the form of block diagrams, program codes are produced automatically with the real time workshop package(RTW), then c compiler compiles the program codes. With this automatic real time program producing mechanism rapid prototyping is realized. To show effectiveness of the proposed designing scheme a DSP-based induction motor vector control system was constructed and implemented

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A Study on the Algebraic Analysis of FDI(failure detection and isolation) in Bilinear System (쌍일차계에 대한 FDI(고장검출 및 분리)의 대수적인 해석에 관한 연구)

  • In, Don-Gi;Cho, Young-Ho;Oh, Min-Hwan;Kim, Jae-Il;Chae, Young-Mu;Ahn, Doo-Soo
    • Proceedings of the KIEE Conference
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    • 2000.07d
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    • pp.2627-2629
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    • 2000
  • This paper introduces the design of a reduced order observer with unknown inputs for the purpose of fault detection and isolation(FDI) in a class of bilinear systems. To Analyze the observer and FDI, this paper uses BPF(block-pulse functions). The operational properties of BPF are much applied to the analysis of bilinear systems. The integral operational matrix BPF converts the form of the differential equation into the algebraic problems.

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A Design of Adaptive Noise Canceller via Walsh Transform (Walsh변환에 의한 적응 잡음제거기의 설계)

  • Ahn, Doo-Soo;Kim, Jong-Boo;Choi, Seung-Wook;Lee, Tae-Pyo
    • Proceedings of the KIEE Conference
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    • 1995.07b
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    • pp.758-760
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    • 1995
  • The purpose of noise cancellation is to estimating signals corrupted by additive noise or interference. In this paper, an adaptive noise canceller is built from a Walsh filter with a new adaptive algorithm. The Walsh filter consists of a Walsh function. Since the Walsh functions are either even or odd functions, the covariance matrix in the tap gain adjustment algorithm can be reduced to a simple form. In this paper, minimization of the mean squre error is accomplished by a proposed adaptive algorithm. The conventional adaptation techniques use a fixed time constant convergence factor by trial and error methods. In this paper, a convergence factor is obtained that is tailored for each adaptive filter coefficient and is updated at each block iteration.

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Design of Kalman Filter via BPF (블록펄스함수를 이용한 칼만필터설계)

  • Ahn, Doo-Soo;Lim, Yun-Sic;Lee, Sung-Hee;Lee, Myung-Kyu
    • Proceedings of the KIEE Conference
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    • 1995.07b
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    • pp.667-669
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    • 1995
  • This paper presents a method to design Kalman filter on continuous stochastic dynamical systems via BPFT(block pulse functions transformation). When we design Kalman filter, minimum error valiance matrix is appeared as a form of nonlinear matrix differential equations. Such equations are very difficult to obtain the solutions. Therefore, in this paper, we simply obtain the solutions of nonlinear matrix differential equations from recursive algebraic equations using BPFT. We believe that the presented method is very attractive and proper for the evaluation of Kalman gain on continuous stochastic dynamical systems.

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A Study on the Current Status and Analysis on the Problem of Unfloored space and Floor Repair in Rural House (농촌주택의 봉당·마루 개보수 현황 및 문제점 분석)

  • Park, Gil-Beom;Park, Jun-Mo;Kim, Ok-Kyue
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2014.11a
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    • pp.117-118
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    • 2014
  • The unfloored space and floor is one of characteristic of traditional house in Korea. This space is used to connecting passage between room or entrance of house. Currently, according to decline of heat insulation property thereby becoming decrepit house, native is repairing it for block external environment such as rain, wind and so on. But, variety problem is happening from wrong repair. This object of this study is current status and analysis on problem of unfloored space and floor repair. As a result, current status of repair is classified repair type, installation position and using form. And position of problem is confirmed connection between original house and extend space.

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A Flowfield Analysis Around an Airfoil by Using the Euler Equations (Euler 방정식을 사용한 익형 주위에서의 유동장 해석)

  • Kim M. S.
    • 한국전산유체공학회:학술대회논문집
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    • 1999.05a
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    • pp.186-191
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    • 1999
  • An Euler solver is developed to predict accurate aerodynamic data such as lift coefficient, drag coefficient, and moment coefficient. The conservation law form of the compressible Euler equations are used in the generalized curvilinear coordinates system. The Euler solver uses a finite volume method and the second order Roe's flux difference splitting scheme with min-mod flux limiter to calculate the fluxes accurately. An implicit scheme which includes the boundary conditions is implemented to accelerate the convergence rate. The multi-block grid is integrated into the flow solver for complex geometry. The flowfields are analyzed around NACA 0012 airfoil in the cases of $M_{\infty}=0.75,\;\alpha=2.0\;and\;M_{\infty}=0.80,\;\alpha=1.25$. The numerical results are compared with other numerical results from the literature. The final goal of this research is to prepare a robust and an efficient Navier-Stokes solver eventually.

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Mechanism of $Zn^{2+}$ Inhibition on Tolaasin Channel Activity

  • Cho, Kwang-Hyun;Kim, Sook-Jin;Kim, Young-Kee
    • Proceedings of the Korean Biophysical Society Conference
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    • 2001.06a
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    • pp.40-40
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    • 2001
  • Tolaasin is a 1.9 kDa peptide produced by Pseudomonas tolaasii and causes a brown blotch disease on cultivated oyster mushrooms. These molecules form channels in the plasma membranes of various cells including red blood cells and destroy cellular structure, known as 'colloid osmotic lysis'. In order to understand the molecular mechanism of tolaasin-mediated channel formation, the effect of Zn$^{2+}$ was investigated on hemolysis and channel formation since Zn$^{2+}$ has been known to block the tolaasin activity.(omitted)ted)

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