• The Journal of Korean Physical Therapy
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• 제17권1호
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• pp.27-42
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• 2005

This study aims to investigate the effect of Early Weight Bearing and Vibration Exercise and is focusing on the difference between changes if experimental before and after on 30 stroke patients. The obtained results are as follows; First, the chang due to Early Weight Bearing and Vibration in the comparison of experimental duration, Early Weight Bearing and Vibration Exercise showed improvement of Bone Density(P<.05). Second, in the comparison of change according to Early Weight Bearing and Vibration Exercise, Bone Density was significantly changed between two experimental group(P<.05). Third, the chang due to Early Welght Bearing and Vibration Exercise, Bone Density of sound femoral head and affected femoral head was significantly changed(P<.05). Fourth, the chang due to Early Weight Bearing and Vibration Exercise, Bone Density of femoral head was significantly changed between two experimental group(P<.05).

• 한국임상수의학회지
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• 제9권2호
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• pp.427-431
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• 1992

This study was performed to investigate the effect of excision arthroplasty of femoral head on walking in dogs. Observations of standing, walking and running were made for 6 months after operation. The recovery periods in excision arthroplasty of femoral head were 21～29 and 71～127 days in small and large dogs, respectively. When the biceps femoris muscle was utilized, the recovery period were 21～29 and 43～57 days in small and large dogs, respectively.

• 대한핵의학회지
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• 제23권2호
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• pp.215-218
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• 1989

Tc-99m-tin colloid distribution in the hip is studied in 76 patients with no hepatic and hip disorder, because knowledge of normal uptake pattern in the hip is important in evaluation of femoral head vasculature after a fracture. The uptake in femoral head is decreased or disappeared with increasing age due to conversion of red marrow to white marrow.

• 한국임상수의학회지
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• 제10권1호
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• pp.47-54
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• 1993

To investigate the effects of sedation, anesthesia and surgery on lymphocyte blastogenesis, the administration of propionyl promzine and ketamine HCI and osteotomy of femoral head either alone of in combination were performed in dogs. Lymphocyte blastogenesis to the PHA-M stimulation was measured by counting $^3H-thymidine$ incorporated. Significant decrease of blastogenesis was observed until 72 hours after treatment in the group treated with propionyl proazine, but only at 4 hours in the group treated with ketamine HCI. In the group in which anesthesia and osteotomy of femoral head were performed blastogenesis decreased significantly until 24 hours after treatment. The present study indicated that transient depression of the lymphocyte blastogenesis after surgery was occurred due to the sedation and anesthesia as well as surgery itself.

• Journal of Yeungnam Medical Science
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• 제40권2호
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• pp.212-217
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• 2023

We report a case of transient osteoporosis of the hip with a femoral neck fracture found during follow-up. A 53-year-old man presented with left hip pain without trauma. The pain did not improve after 2 weeks and he was brought to our hospital by ambulance. Magnetic resonance imaging (MRI) of the left hip joint showed diffuse edema in the bone marrow, which was identified by low signal intensity on T1-weighted images, high signal intensity on T2-weighted images, and increased signal intensity on short tau inversion recovery. This edema extended from the femoral head and neck to the intertrochanteric area. He was diagnosed with transient osteoporosis of the left hip. Rest gradually improved his pain; however, 3 weeks later, his left hip pain worsened without trauma. X-ray, computed tomography, and MRI results of the hip joint demonstrated a left femoral neck fracture, and osteosynthesis was performed. Differential diagnoses included avascular necrosis of the femoral head, infection, complex regional pain syndrome, rheumatoid arthritis, leukemia, and other cancers. Transient osteoporosis of the hip generally has a good prognosis with spontaneous remission within a few months to 1 year. However, a sufficient length of follow-up from condition onset to full recovery is necessary to avoid all probable complications such as fractures.

• 한방재활의학과학회지
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• 제32권3호
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• pp.37-53
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• 2022

Objectives This study was conducted to investigate a randomized controlled trial study on the clinical treatment of herbal medicines for avascular necrosis of the femoral head. Methods By March 2022, the China National Knowledge Infrastructure (CNKI) was reviewed about randomized controlled trial studies on the herbal treatment of avascular necrosis of the femoral head through. The publication year, evaluation criteria, treatment period, treatment method and effectiveness were analyzed for articles published from 2017 to 2022. Results 16 articles were selected and 14 kinds of herbal medicines were used. In most studies, Western medical treatments such as injection therapy, oral drug administration, traction therapy and mid-frequency electric therapy were treated alone in the control group, and a combination of Western medical treatment and herbal treatment was administered to the experimental group. Conclusions In China, there have been many studies on herbal treatment for avascular necrosis of the femoral head. In Korea, more clinical studies on the herbal treatment of avascular necrosis of the femoral head are needed. This study will be helpful for future research in Korean medicine on avascular necrosis of the femoral head.

• 한국임상수의학회지
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• 제27권3호
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• pp.240-245
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• 2010

대퇴골 머리의 골괴사는 특발성이며 진행성 질환이다. 골괴사증 연구를 위한 다양한 동물모델이 보고되었지만, 현재까지 표준화된 동물모델은 완성되지 않았다. 본 연구에서 랫드에서 세가지 외과적인 방법으로 유발한 골괴사모델을 비교하였다. 20마리의 SD 랫드 (24주령, 숫컷)를 각 5마리씩 대조군과 세개의 실험군으로 구분하였다. 세가지 외과적인 방법으로 골괴사를 유발하였다. 원인대를 자르고, 대퇴골목의 골막을 절개 (S군), 철사를 대퇴골목에 결찰 (W군), W군과 동일한 방법으로 대퇴골목에 철사를 감은 후, 전기소락기의 끝을 철사에 접촉시켜 소락, 그리고 철사를 제거 (B군). 2주후, 랫드는 안락사하고 대퇴골 머리와 목을 채취하였다. H/E 염색, 사프라닌 O염색, TUNEL 염색을 실시하여 대퇴골 머리의 골과 연골에 골괴사 병변을 평가하였다. 모든 외과적인 방법 (S, W, B군)에서 골괴사가 2주간의 단기간에 유발되었다. 연골부분에 대한 유의적인 괴사변화는 B군에서만 관찰되었다. 철사를 통한 소락 후, 철사를 제거하는 변형된 외과적 방법은 다른 방법에 비해 더욱 효과적으로 골괴사 실험모델을 완성하였다.

• 한방재활의학과학회지
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• 제33권1호
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• pp.47-59
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• 2023

Objectives This paper is an analysis of domestic and foreign trends for the Korean medical treatment of avascular necrosis of the femoral head. Methods Domestic and foreign databases were searched and analyzed for Korean medical treatment interventions, research types, and treatment effects for avascular necrosis of the femoral head. Results There were 10 case reports in Korea, 2 case reports and 3 randomized controlled studies abroad. A total of 12 treatment interventions were used, and the types include acupuncture, herbal medicine, phamacopunture, electroacupuncture, cupping, physical therapy, chuna, acupotomy, moxibustion, warm acupuncture, laser acupuncture, and motion style treatment. As for the evaluation index, visual analogue scale, range of motion and harris hip score were the most common with 7 cases each. Conclusions Through this study, it was possible to understand the trends of domestic and foreign research on the treatment of avascular necrosis of the femoral head with Korean medicine. However, due to the small number of literature and no randomized control studies in Korea, treatment evidence is insufficient. It is considered that further research is needed in the future.

• Journal of Acupuncture Research
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• 제39권4호
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• pp.239-248
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• 2022

To determine the effect of Korean medicine treatment of avascular necrosis of the femoral head (ANFH) this study reviewed both single ingredients and bioactive compounds in the treatment of ANFH in a rat model. Literature was retrieved from PubMed and Google Scholar using the keywords "femur head necrosis," "natural extract," and "rat." The data from studies analyzed included: rats' characteristics, development methods of ANFH, natural extracts administration, observation methods, and outcome indicators. Two independent researchers screened all articles retrieved and 26 studies were chosen. The most used rat species was the Sprague Dawley rat (76.9%). To induce ANFH, steroid injections (46.2%), and oral gavage (53.8%) were typically used. Studies focused mainly on factors affecting bone formation (65.3%), and apoptosis (53.8%). Research on ANFH focused on using traditional natural substances mentioned in classical literature to confirm its effectiveness against anti-inflammation, osteogenesis, and cell death. ANFH has a diverse etiology, therefore research models such as genetic analysis of human-derived samples from ANFH patients may shed more light on the condition. Moreover, research into herbal medicines and pharmacoacupuncture treatment of ANFH should precede.

• Hip & pelvis
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• 제35권3호
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• pp.147-156
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• 2023

Osteonecrosis of the femoral head (ONFH), a condition characterized by the presence of a necrotic bone lesion in the femoral head, is caused by a disruption in the blood supply. Its occurrence is more common in young and middle-aged adults and it is the main reason for performance of total hip arthroplasty in this age group. Its incidence is increasing along with increased use of glucocorticoids for management of adjuvant therapy for treatment of leukemia as well as organ transplantation and other myelogenous diseases. Current information on etiology and pathogenesis, as well as natural history, stage system, and treatments is provided in this review. A description of the Association Research Circulation Osseous (ARCO) criteria for classification of glucocorticoids-and alcohol-associated ONFH, 2019 ARCO staging system, and 2021 ARCO classification using computed tomography for the early stages of ONFH is also provided.