• Archives of Pharmacal Research
• /
• v.25 no.4
• /
• pp.511-521
• /
• 2002

The purpose of this study was to determine whether bromocriptine affects the catecholamines (CA) secretion evoked in isolated perfused rat adrenal glands, by cholinergic stimulation, membrane depolarization and calcium mobilization, and to establish the mechanism of its action. The perfusion of bromocriptine ($1~10{\;}{\mu}M$) into an adrenal vein, for 60 min, produced relatively dose-dependent inhibition in the secretion of catecholamines (CA) evoked by acetylcholine (ACh, 5.32 mM), DMPP ($100{\;}{\mu}M$ for 2 min), McN-A-343 ($100{\;}{\mu}M$ for 2 min), cyclopiazonic acid (CPA, $10{\;}{\mu}M$ for 4 min) and Bay-K-8644 ($10{\;}{\mu}M$ for 4 min). High $K^+$ (56 mM)-evoked CA release was also inhibited, although not in a dose-dependent fashion. Also, in the presence of apomorphine ($100{\;}{\mu}M$), which is also known to be a selective $D_2$-agonist, the CA secretory responses evoked by ACh, high potassium, DMPP, McN-A-343, Bay-K-8644 and cyclopiazonic acid were also significantly depressed. However, in adrenal glands preloaded with bromocriptine ($3{\;}{\mu}M$) in the presence of metoclopramide ($15{\;}{\mu}M$), a selective $D_2$-antagonist, the CA secretory responses evoked by ACh, high potassium, DMPP, McN-A-343, Bay-K-8644 and cyclopiazonic acid considerably recovered as compared to that of bromocriptine only. Taken together, these results suggest that bromocriptine can inhibit the CA secretion evoked by stimulation of cholinergic receptors, as well as by membrane depolarization, in the perfused rat adrenal medulla. It is thought this inhibitory effect of bromocriptine may be mediated by inhibiting the influx of extracellular calcium and the release from intracellular calcium stores, through the activation of dopaminergic $D_2$-receptors located in the rat adrenomedullary chromaffin cells. Furthermore, these findings also suggest that the dopaminergic $D_2$-receptors may play an important role in regulating adrenomedullary CA secretion.

• Textile Coloration and Finishing
• /
• v.25 no.3
• /
• pp.223-231
• /
• 2013

This research has a main focus on providing fundamental data for on-the-spot industrial fields by comparing and contrasting physical properties of fluffy spun-like material. The fluffy spun-like yarn is developed as fluffy yarn similar to natural spun-like yarn by treating polyester(FDY and + type shaped DTY) with ATY machine. In this experiment, using ATY machine for raw material texturing, we produced two fluffy yarns: (i) + type shaped(50d/36f, DTY) as core yarn and 100d/192f FDY as effect yarn[ATY(D)], (ii) FDY(75/36) as core yarn and 100d/192f FDY [ATY(F)] as effect yarn. After producing thous yarns, we twisted them with 500T/M, 700T/M, 1000T/M, respectively. produced yarns through this process were used as the samples for this experiment. Even though the shrinkage of fluffy yarn ATY(F) and ATY(D) becomes high as treated temperature rises and treated time lengthens, it is more affected by treated temperature then by treated time. In this experiment, produced fluffy yarn[ATY(D)] shows a little high values for temperature, but almost same values for higher temperatures. When we compare ATY(F) with ATY(D) fluffy yarn shows more natural fluffy yarn surface structure like natural cotton. The shrinkage of 700T/M twisted ATY(D) fluffy yarn show about 11% under treated temperature $180^{\circ}C$ and treated time 30min, and about 7% under $120^{\circ}C$ and 30min, respectively. But the shrinkage of 1000T/M fluffy yarn shoes about 9% and 6% under same conditions. Regarding treated time, tenacity and initial modulus of ATY(D) fluffy yarn rise high until 30min, but do not show much increase above 30min. Regarding treated temperature, tenacity and initial modulus of it rise high aboyer $140^{\circ}C$.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2022.05a
• /
• pp.329-332
• /
• 2022

본 연구에서는 하나의 2D 이미지를 StyleGAN을 통해 다각도의 이미지를 생성하고, 그것을 다시 Kaolin으로 구현한 역그래픽 렌더러의 입력으로 받아 3D 오브젝트로 변환한다. 또한, 클레이튼 기반의 블록체인을 통해 NFT 기술을 통하여 3D 오브젝트를 NFT로 만들 수 있도록 한다. 최종적으로 2D 이미지를 메타버스에서 활용할 수 있는 3D 패션 아이템으로 변환하고 NFT를 발행하여 거래한다. 본 연구는 개인이 자유롭게 메타버스 콘텐츠를 제공하고 거래하여 메타버스 활성화에 기여할 것으로 기대한다.

• ETRI Journal
• /
• v.33 no.6
• /
• pp.897-903
• /
• 2011

A hybrid ${\Delta}{\Sigma}$ modulator for audio applications is presented in this paper. The pulse generator for digital-to-analog converter alleviates the requirement of the external clock jitter and calibrates the coefficient variation due to a process shift and temperature changes. The input resistor network in the first integrator offers a gain control function in a dB-linear fashion. Also, careful chopper stabilization implementation using return-to-zero scheme in the first continuous-time integrator minimizes both the influence of flicker noise and inflow noise due to chopping. The chip is implemented in a 0.13 ${\mu}m$ CMOS technology (I/O devices) and occupies an active area of 0.37 $mm^2$. The ${\Delta}{\Sigma}$ modulator achieves a dynamic range (A-weighted) of 97.8 dB and a peak signal-to-noise-plus-distortion ratio of 90.0 dB over an audio bandwidth of 20 kHz with a 4.4 mW power consumption from 3.3 V. Also, the gain of the modulator is controlled from -9.5 dB to 8.5 dB, and the performance of the modulator is maintained up to 5 nsRMS external clock jitter.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2022.11a
• /
• pp.922-924
• /
• 2022

본 연구에서는 2D 이미지 파일을 NFT 3D 패션 아이템으로 변환하여 거래할 수 있도록 한다. 한 장의 2D 이미지가 SMR을 통해 3D 오브젝트로 변환된다. 변환된 오브젝트는 KIP-17 기반의 스마트 컨트랙트를 통해 NFT을 발행할 수 있도록 환경을 구축하고, 최종적으로 NFT를 거래할 수 있는 플랫폼을 제공한다.

• Journal of the Institute of Electronics Engineers of Korea SD
• /
• v.44 no.8
• /
• pp.16-21
• /
• 2007

CMOS variable gain amplifier (VGA) IC designs for the structure monitoring systems of the telemetries were developed. A three stage cascaded VGA using a differential amplifier and a linear-in-dB controller is presented. A proposed VGA is a modified version of a conventional VGA such that the gain is controlled in a linear-in-dB fashion through the current ratio. The proposed VGA circuit introduced in this paper has a dynamic range of 77 dB with 1.5 dB gain steps. It also achieved a gain error of less than 1.5 dB over 77 dB gain range. The VGA can operate up to 10MHz dissipating 13.8 mW from a single 1.8 V supply. The core area of the VGA fabricated in a Magnachip $0.18{\mu}m$ standard CMOS process was about $430{\mu}m{\times}350{\mu}m$. According to measurement results, we can verify that the proposed method is reasonable with regard to the enhancement of dynamic range and the better linear-in-dB characteristics.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.23 no.3
• /
• pp.443-452
• /
• 1994

This study describes the effects of novel1, 25-dihydroxyvitamin D$_3$ analong[1,25(OH)$_2$-16ene-23yne-26, 27-F6-D$_3$] on proliferation of the human histiocytic lymphoma cell line U937 in vitro. We also examined the expression of c-myc oncogene in U937 cells was apparently inhibited to 62% and 87% of the control level after 4 days in the presence of 10-8M and 10-7 M of this analog, respectively. This compound morpholgically and functionally differentiated U937 cells to nonocyte-macrophage phenotype showing the increase of adherence ability to surface and a decrease of N/C ratio in Giemsa staining . Especially, nonspecific esterase activity which is a marker of cell differentiation to monocyte-macrophage was positive, and production of the positive stained cells increased in a dose dependent fashion . The expression of c-myc oncogene by 1, 25(OH)$_2$D$_3$ analog(10-7 M) was reduced by 60% at the mRNA level as determined by Northern blotting. The effects of this novel analog on cell proliferation and cell differentiation may open op new therapeutic strategies for human disorders such as psoriassis and may provide a tool to understand the mechanism of action of vitamin D$_3$ seco-steroids in malignancy.

• Electronics and Telecommunications Trends
• /
• v.36 no.3
• /
• pp.12-22
• /
• 2021

Since the technical realization of self-aligned planar complementary metal-oxide-semiconductor field-effect transistors in 1960s, semiconductor manufacturing has aggressively pursued scaling that fruitfully resulted in tremendous advancement in device performances and realization of features sizes smaller than 10 nm. Due to many intrinsic material and technical obstacles, continuing the scaling progress of semiconductor devices has become increasingly arduous. As an effort to circumvent the areal limit, stacking devices in a three-dimensional fashion has been suggested. This approach is commonly called monolithic three-dimensional (M3D) integration. In this work, we examined technical issues that need to be addressed and overcome to fully realize energy efficiency, short latency and cost competency. Full-fledged M3D technologies are expected to contribute to various new fields of artificial intelligence, autonomous gadgets and unknowns, which are to be discovered.

• Fashion & Textile Research Journal
• /
• v.1 no.3
• /
• pp.264-274
• /
• 1999

The thermal resistance of 60 men's suits for summer and winter was measured to determine their thermal characteristics and physical properties, including air permeability, weight, and thickness of the jackets and trousers consisted of the ensembles were measured to predict the thermal resistance of garments and ensembles. In this study, general physical properties of the men' suit ensembles were determined. In general, thickness and weight of winter ensembles were greater than those of summer ensembles. A factor which could distinguish the difference between summer and winter ensembles was the air permeability. The air permeability of summer ensembles was 3~6 times greater than those of winter ensembles. For the thermal characteristics, the thermal resistance of winter ensembles were higher than those of summer ensembles. When the wind was involved, the thermal resistance of both ensembles decreased up to 30%. In addition, the equations were developed to predict the thermal resistance of the garments and ensembles when there was no air velocity and the thermal resistance of the ensembles with air velocity of 1.2 m/sec. Looking at the equations, thickness, weight, and size of the garments were the definite factors that affect the thermal resistance of the samples.

• Proceedings of the Korean Institute of Interior Design Conference
• /
• 2008.05a
• /
• pp.190-195
• /
• 2008

Aggressive behavior and the purchase of systematic marketing strategy and the marketing strategy is applied consistently integrated image management needs. However, domestic fashion brand shops selling space, the reality is reckless use of the design elements and an age, and despite a high level of sales, but consumers are not getting the environment will he provided. Teenie Winnie the characteristics of burial space and tim ENC literature, materials, research through the local environment, architectural design, the human aspect, the store environment, external components, the investigation focuses on internal components. Maketing aspects, VP, IP, PP josago to systematically on a colorful aspects of the comparative analysis would be linked up. Winnie the characteristics of burial space and tim ENC literature, materials, research through the local environment, architectural design, the human aspect, the store environment, external components, the investigation focuses on internal components. Maketing aspects, VP, IP, PP josago to systematically on a colorful aspects of the comparative analysis would be linked up. First, the design aspects of the human environment, architecture, environmental stores, external components, internal components can be divided into The brand image and concept of same-store environment of mutual relations in other stores. The interior is an important element in order to draw attention to consumer needs.