• Parasites, Hosts and Diseases
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• 제34권2호
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• pp.143-150
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• 1996

애완견에서 진드기에 의한 피부병의 빈토 및 원인 진드기를 조사하고 인체의 소양성 피부 질환의 원인으로 애완견 진드기의 의의를 조사하기 위하여 1990년 1월부터 1995년 12월까지 청운동물병원에서 귀 부위에 피부병이 있었던 970마리의 애완견의 털과 인설에서 진드기를 수세법으로 검출하고 분류하였으며 가족의 소양성 피부질환 유무를 조사하였다. 애완견 피부염의 원인으로 추정되는 진드기로는 Qctodectes Wnotis Hering. 1,838 (귀진드기)와 Sarcoptes canis Gerlach. 1,857 (개옴진드기)가 검출되었으며 귀진드기는 970마리의 애완견 중 382마리 (39.4%)에서 총 2 117마리가 검출되었다. 개옴진드기는 970마리의 애완견 중 3마리 (0.3%)에서 총 30마리가 검출되어 원인 진드기가 검출된 애완견은 970마리 중 385마리 (39. 7%)이었다. 귀진드기가 검출된 382마리의 애완견 사육 가족 중 2가족에서 소양성 피부질환이 발생하였으나 귀진드기와는 관련이 없었으며 개옴진드기가 검출된 3마리의 애완견 사육 가족 중 2가족에서 개옴진드기에 의한 것으로 추정되는 피부염이 발생하였다. 그러므로 본 저자들은 귀진드기가 애완견에서 가장 흔히 검출되는 진드기이지만 사람에게 전파되어 피부염을 유발하지 않으며 개옴진드기는 감염률은 매우 낮지만 사람에 전염성이 강함을 확인하였다.

• Journal of Veterinary Science
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• 제21권4호
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• pp.63.1-63.9
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• 2020

Background: Canine adenovirus type 2 (CAV-2) induces infectious laryngotracheitis in members of the family Canidae, including dogs. To date, no ELISA kits specific for CAV-2 antibody have been commercialized for dogs in Korea. Objectives: We aimed to develop new indirect enzyme-linked immunosorbent assay (I-ELISA) to perform rapid, accurate serological surveys of CAV-2 in dog serum samples. Methods: In total, 165 serum samples were collected from dogs residing in Chungbuk and Gyeongbuk provinces between 2016 and 2018. The Korean CAV-2, named the APQA1701-40P strain, was propagated in Madin-Darby canine kidney cells and purified in an anion-exchange chromatography column for use as an antigen for I-ELISA. The virus-neutralizing antibody titers of CAV-2 in the dog sera were measured by virus neutralization (VN) test. Results: We compared the results obtained between the VN and new I-ELISA tests. The sensitivity, specificity, and accuracy of new I-ELISA were 98.6%, 86.4% and 97.0% compared with VN test, respectively. New I-ELISA was significantly correlated with VN (r = 0.91). Conclusions: These results indicate that new I-ELISA is useful for sero-surveillance of CAV-2 in dog serum.

• 한국의류산업학회지
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• 제7권3호
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• pp.270-276
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• 2005

Nowadays, the family system has changed from a large extended family group to a more nuclear family and the number of people who live by themselves has been increasing. Moreover, Korea is becoming an aged society, and pets are becoming more important as leave the family home. So a lot of people in Korea now consider pets as their family members due largely to the drastic change of their life style. Therefore, the rate of importing commodities for pets like cats and dogs has been increasing dramatically. In this study, in response to the growing interest in the pet industry, I have studied recent trends and types in the pets wear markets which are still in the first stage of development in Korea. In order to enhance the possibility of mass producing pets ready-made clothes for making the unit cost lower, firstly, I presented a new basic design and pattern of pets wear made up of general textile. After that, following basic purpose of pet wear, I classified decorative clothes into party wear, everyday wear and street wear and then I developed the pattern and made a pair of works for each item totaling 6 in all. I hope that the number of Korean companies which can enhance their reputation through by marketing these products in Korean as well as all around the world will increase. I believe this will be possible because by taking advantage of the easy pattern developed in this thesis. They will be able to mass produce their own high quality pets wear brand.

• Communications for Statistical Applications and Methods
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• 제14권3호
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• pp.541-549
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• 2007

Testing the sibling relationship becomes more important issue in many cases such as the reunion of dispersed family members whose parents have already passed away and the discrimination between pure-bred and crossbred dogs. Analysis of the sibling case is different from that of the paternity case. In this paper, we describe how to evaluate and determine the sibling relationship by comparing sibling pairs with unrelated pairs. We use the Korean population with 17 independent STR loci system to propose a discrimination rule.

• 혜화의학회지
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• 제22권1호
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• pp.57-70
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• 2013

Objective: Today, the public concern for 'Companion Animal" as a family member is ever increasing. Accordingly, the cases of traditional veterinary medicine treatment targeting a companion animal has been increasing, but the traditional records in literature about this have hardly ever been introduced to academic circles. Hereupon, this writing is intending to collect the prescriptions, which were once used for treating canine diseases, in order to report them to academic circles first. Method: This writing recorded the information about canine diseases and their treatment from the books related to the orthodox oriental medicine in East Asia, and analyzed their meanings. Result: Intial records about canine diseases are found in East Asian traditional medicine books including "Bonchoseubyu"(741), "Ilwhajajegaboncho"(unidentifiable period), "Jeungryuboncho"(1082), etc. The disease perceived by humans at that time was "gwa"(a boil) which is a kind of skin ailments. In addition, these medicine books show that people at that time concentrated on the value of use of a dog as meat rather than a pain of a dog's diseases. "Hwalsujaju"(1873)which was established during the Qing Dynasty leaves the most abundant data on canine diseases. This book perceived a dog as a precious existence watching over human housing and property, according to which, canine diseases and treatment methods are subdivided. The prescriptions for a dog's disease in our country are identifiable only in "Jeungbodanbangshinpyeon"(1913)과 "Bijeongmanbyeongtongchibeop"(1933). These books include the prescriptions not only for a dog's disease but also for a disease of a cow, horse, sheep, chicken, and pig, etc. which are familiar to us. Conclusion: The prescriptions used for a dog in East Asia were different from those for people. It was found that they used a medicine noticeably for external application for easy treatment, and in case of the use of an internal medicine, they adopted a method of getting dogs to take a medicine mixed with rice or porridge for dogs. Such a clue will be applied to the traditional- medicine-based treatment of a companion animal for the time to come.

• 대한수의학회지
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• 제49권4호
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• pp.285-290
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• 2009

This study was performed to investigate the possibility of superfecundation by surgical intrauterine artificial insemination in dogs of confirmed genetic pedigree. Artificial insemination was performed on 3 days after ovulation with $1.3{\times}$ $10^8$ spermatozoa. Five puppies were delivered on 60 days after insemination. The ratio of the number of newborns to the number of corpora lutea was 83.3% (5/6). Parentage analysis with 10 canine-specific microstatellite markers demonstrated that one puppy was genetically relative to the sire-A family and four puppies were genetically relative to the sire-B. The present study demonstrated that two kinds of puppies with different genetic pedigree can be produced by surgical uterine insemination of semen of individual dog into each uterine horn of a bitch.

• 한국임상수의학회지
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• 제7권2호
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• pp.521-525
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• 1990

Microspoum canis에 감염된 개 및 고양이와 직접 접촉한 경험이 있는 5명의 환자를 조사하여 동물기생체로서의 이 진균의 중요성을 확인하였다. ring worm의 전형적인 병변은 신체의 노출된 부위에만 발생하였다. M. canis는 환자와 감염된 애완동물의 피부병변에서 분리되었으며 피부 시료로부터 직접 증명되었다. 그림에도 불구하고 비접촉군과 사물성환경으로 부터는 증명되지 않았다. 사람, 개 및 고양이에서 분리된 진균들은 육안적으로나 현미경적으로 서로 비슷한 형태를 나타내었다. 이 진균들의 유전학적 연구결과는 교배(-)형이었다. 동물기호성 표재성진균의 전염은 직접적인 접촉에 의해 자주 일어나는 것으로 사료된다. 이감염증에 대한 역학과 예방방법에 대해 고찰하였다.

• 한국임상수의학회지
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• 제27권1호
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• pp.83-87
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• 2010

양성자(Hermaphroditism)는 사람과 동물에서 매우 드물게 발생단계의 이상으로 발생한다. 한국에서 개의 양성자 발생 보고는 6 사례가 있으며 그들 모두가 American Cocker Spaniel 품종이었다. 본 연구자들은 진돗개에서 발생한 양성자 사례를 발견하고 그 특징 분석과 병리조직학적 연구 및 분자생물학적 성별감별 연구를 수행하였다. 본 사례연구를 통하여 os clitoris와 ovotestes를 가지며 암컷 성을 가진 양성자 진돗개를 최초로 확인하고 보고하는 바이다.

• Journal of information and communication convergence engineering
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• 제19권4호
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• pp.234-240
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• 2021

As the number of pet dog-related businesses is rising rapidly, there is an increasing need for reliable pet dog health information systems for casual pet owners, especially those caring for older dogs. Our goal is to implement a mobile pre-diagnosis system that can provide a first-hand pre-diagnosis and an appropriate coping strategy when the pet owner observes abnormal symptoms. Our previous attempt, which is based on the fuzzy C-means family in inference, performs well when only relevant symptoms are provided for the query, but this assumption is not realistic. Thus, in this paper, we propose a hybrid inference structure that combines fuzzy association memory and a double-layered fuzzy C-means algorithm to infer the probable disease with robustness, even when noisy symptoms are present in the query provided by the user. In the experiment, it is verified that our proposed system is more robust when noisy (irrelevant) input symptoms are provided and the inferred results (probable diseases) are more cohesive than those generated by the single-phase fuzzy C-means inference engine.

• 대한약리학회지
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• 제28권2호
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• pp.147-162
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• 1992

Pancreatic polypeptide family펩타이드들의 뇌혈관 평활근 수축성에 미치는 효과를 관찰하고, cyclic nucleotide 활성제 및 칼륨통로개방제와의 상호작용을 관찰하기 위하여 다음과 같은 실험을 하였다. 체중 $20{\sim}30\;g$의 개를 사혈 희생시켜 두개골을 절개한 후 뇌저동맥과 중뇌동맥을 적출하였다. 적출된 동맥편은 $4^{\circ}C$의 생리적식염수 내에서 나선형 절편으로 만들어 0.3%의 CHAPS 용액에 침잠시킴으로써 내피세포층을 제거한 후 95% $O_2$와 5% $CO_2$의 혼합기체로 포화된 $37^{\circ}C$의 Krebs-Henseleit 용액을 포함한 적출근편실험조에서 등척성 장력을 측정하였다. 1. PP, PYY 및 NPY는 뇌동맥 나선형절편을 농도의존적으로 수축시켰으며, 그 효력과 효능은 PYY가 가장 강하였고, 그 다음이 NPY, 그리고 PP의 순이었다. 이들의 효력은 노르아드레날린보다 20내지 200배 강하였으며, 그 중 PYY는 5-HT 보다도 강한 효력을 보였다. 2. Cyclic AMP 활성제인 forskolin과 cyclic GMP 활성제인 sodium nitroprusside는 뇌동맥절편의 기본장력을 감소시켰으며, PP, PYY 및 NPY 유발수축 역시 농도의존적으로 억제하였다. 이 때 forskolin의 기본장력억제작용이 sodium nitroprusside보다 강한 효력을 나타내었다. 3. 칼륨통로 개방제인 RP 49356, P 1060 및 BRL 38227은 기본장력에 대해서는 공히 농도의존적으로 억제하였으나, PP, PYY 및 NPY 유발수축에 대해서는 P 1060만이 농도의존적으로 억제하였고, RP 49356 및 BRL 38227은 약간 억제하는 경향만을 보였는데, 특기할 것은 저농도의$(0.1\;{\mu}M)$ BRL 38227이 이들 펩타이드 유발수축을 오히려 증가 시켰다는 것이다. 4. 기본장력에 대해서, 칼륨통로개방제들은 forskolin의 이완작용에 유의한 영향을 미치지 못하였으나, 그중 P 1060과 BRL 38227은 sodium nitroprusside의 이완작용을 상승적으로 강화하였다. PYY$(0.1\;{\mu}M)$유발 수축작용에 대해서, 칼륨통로 개방제들은 forskolin의 수축억제작용에 대해서는 약간 길항하는 경향만을 보였고, sodium nitroprusside의 수축억제작용은 유의하게 길항하였다. 이상의 결과들을 종합하면, 개의 뇌혈관에서는 NPY 뿐만 아니라 PYY도 혈관수축기전에 중요한 역할을 한다고 볼 수 있으며, 그 수축작용의 기전에는 세포내 cAMP 및 cGMP 활성도의 변화가 포함된다고 사료된다. 또 칼륨통로개방제들은 pancreatic polypeptide family의 뇌혈관수축작용에 대하여 제제 및 농도에 따라 다양한 영향을 미치므로 이에 대한 향후의 더욱 세밀한 연구가 요구된다.