[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.5351/CKSS.2007.14.3.541

Statistical Evaluation of Sibling Relationship

Lee, Jae-Won (Department of Statistics, Korea University)
Lee, Hye-Seung (Pediatrics Epidemiology Center, University of South Florida)
Lee, Hyo-Jung (Department of Statistics, Korea University)
Hwang, Juck-Joon (Department of Legal Medicine, Korea University)

Publication Information

Communications for Statistical Applications and Methods / v.14, no.3, 2007 , pp. 541-549 More about this Journal

Abstract

Testing the sibling relationship becomes more important issue in many cases such as the reunion of dispersed family members whose parents have already passed away and the discrimination between pure-bred and crossbred dogs. Analysis of the sibling case is different from that of the paternity case. In this paper, we describe how to evaluate and determine the sibling relationship by comparing sibling pairs with unrelated pairs. We use the Korean population with 17 independent STR loci system to propose a discrimination rule.

Keywords

Sibling relationship; likelihood ratio; sensitivity; specificity; error rate;

Citations & Related Records

Reference

1	Boehnke, M. and Cox, N. J. (1997). Accurate inference of relationships in sib-pair linkage studies. American Journal of Human Genetics, 61, 423-429 DOI ScienceOn
2	Chakraborty, R. and Jin, L. (1993a). Determination of relatedness between individuals using DNA fingerprinting. Human Biology, 65, 875-895
3	Chakraborty, R. and Jin, L. (1993b). A unified approach to study hypervariable polymorphisms: statistical considerations of determining relatedness and population distances. In: Pena SDJ, Chakraborty R, Epplin JT, Jeffreys A (eds) DNA fingerprinting: state of the science. Birkhaeuser Verlag, Basel, 153-175
4	Ehm, M. G. and Wagner, M. (1996). Test statistic to detect errors in sib-pair relationships. American Journal of Human Genetics (supplement), 59, A217
5	Goring, HHH and Ott, J. (1995). Verification of sib relationship without knowledge of parental genotypes. American Journal of Human Genetics, 57, A192
6	Lee, J. W., Lee, H. S., Park, M. and Hwang, J. J. (2001). Paternity determination when the alleged father's genotypes are unavailable. Forensic Science International, 123, 202-210 DOI ScienceOn
7	Strivers, D. N., Zhong, Y., Hanis, C. L., and Chakraborty, R. (1996). RELTYPE: a computer program for determining biological relatedness between individuals based on allele sharing at microsatellite loci. American Journal of Human Genetics (supplement), 59, A190
8	Thompson, E. A. (1975). The estimation of pairwise relationships. Annals of Human Genetics, 39, 173-188 DOI ScienceOn