• Korean Journal of Exercise Nutrition
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• v.13 no.1
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• pp.45-50
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• 2009

This study evaluated the effects of D-ribose supplementation on exercise time in a hypoxic chamber. Eight healthy young males participated in experiments under all four different conditions; placebo+normoxic, placebo+hypoxic, ribose+normoxic, and ribose+hypoxic. Subjects took 1 g per 10 kg body weight of ribose dissolved in drinking water 30 minutes before and immediately before running. We observed the run-to-exhaustion time, the maximum heart rate, and the changing pattern of the heart rate during exercise. The longest running time was achieved when subjects ran under normoxic condition with ribose supplementation. The shortest running time occurred when subjects ran under hypoxic conditions without ribose supplementation. We measured MDA and GPx to determine any changes in oxidative stresses or antioxidative systems. MDA was affected by the environmental conditions and the running time. The activity of GPx showed a significant difference only with the different environmental conditions of exercise. The results of this study indicate that ribose can be considered a possible ergogenic during exercise in specific conditions, but more detailed and well-controlled studies are needed to make a definitive conclusion.

• IMMUNE NETWORK
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• v.20 no.1
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• pp.2.1-2.19
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• 2020

Acute viral infection or vaccination generates highly functional memory CD8 T cells following the Ag resolution. In contrast, persistent antigenic stimulation in chronic viral infection and cancer leads to a state of T-cell dysfunction termed T-cell exhaustion. We and other have recently identified a novel subset of exhausted CD8 T cells that act as stem cells for maintaining virus-specific CD8 T cells in a mouse model of chronic lymphocytic choriomeningitis virus infection. This stem cell-like CD8 T-cell subset has been also observed in both mouse and human tumor models. Most importantly, in both chronic viral infection and tumor models, the proliferative burst of Ag-specific CD8 T cells driven by PD-1-directed immunotherapy comes exclusively from this stem cell-like CD8 T-cell subset. Therefore, a better understanding of the mechanisms how CD8 T-cell subsets are regulated during chronic viral infection and cancer is required to improve the current immunotherapies that restore the function of exhausted CD8 T cells. In this review, we discuss the differentiation of virus-specific CD8 T cells during chronic viral infection, the characteristics and function of CD8 T-cell subsets, and the therapeutic intervention of PD-1-directed immunotherapy in cancer.

• Management & Information Systems Review
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• v.33 no.5
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• pp.1-34
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• 2014

This study suggests internal and external virtuous behavior in organization influenced employees' organizational citizenship behavior (OCB), organizational loyalty and emotional exhaustion through mediated effect of affective commitment and collective self-esteem. Virtue in organization has received attention as critical attribute of positive organizational scholarship. Cameron(2003) defined the study of virtue as a study of the capacity, attributes, and reserve in organization that facilitates the expression of positive deviance among organization member. Accordingly, this study presumed that virtuous behaviors within organization positively associate with OCB, and organizational loyalty through affective commitment whereas the virtuous behaviors negatively influence emotional exhaustion. On the other hand, we assumed that external virtuous behaviors positively associate with OCB and organizational loyalty and negatively associate with emotional exhaustion individually. In study 1, we conducted interview with Korean employees created items for internal and external virtue, and implemented empirical study for 253 employees of domestic companies in study 2. This study contributes to the empirical investigation on how internal virtue (i.e. the employees' virtue for their organization) and external virtue (i.e. the organization's virtue for society), used as independent variables, influence employees' organizational citizenship behavior (OCB), organizational loyalty and emotional exhaustion after creating items for the two virtuous behaviors through qualitative research.

• The Journal of the Convergence on Culture Technology
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• v.9 no.1
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• pp.205-211
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• 2023

The purpose of this study is to identify what factors actually affect the turnover intentions of social workers. It is an important task to grasp the factors of turnover of the social worker through empirical analysis because the high turnover rate of social welfare workers in Korea has a negative influence on their organization and ultimately impedes the stable delivery of social welfare services. This study used the results of analyzing 100 social workers in social service companies. In fact, the data used in this study were statistically analyzed only for 82 subjects, except for 18 subjects who did not respond to the variables used. As a result, the general effects of job stress on job turnover and job exhaustion were examined as much as possible. We examined the effect of job stress, an independent variable, on the turnover and exhaustion of social workers. Specifically, job stress was divided into role, organizational, and relationship, and it was found that role - related factor job stress only affected social workers' turnover intention significantly. In addition, the relationship-related affected the exhaustion of the social worker. Therefore, in order to reduce the exhaustion of the social worker, the desirable direction to reduce the stress of the relationship-related factor should be sought.

• Industry Promotion Research
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• v.9 no.3
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• pp.251-261
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• 2024

The purpose of this study is to improve welfare services for the socially underprivileged, the disabled, by improving and streamlining the work environment of workers at day care facilities for the disabled. The research question consisted of three issues: conflict between employees, psychological exhaustion, and growth factors experienced as a Christian worker at a day care facility for the disabled. As a research method, from January 2024 to April 2024, 10 Christian workers working at a day care facility for the disabled were interviewed and collected facts about their experiences during the work process using Colaizzi's phenomenological research method. analyzed. According to the research results, the psychological processes experienced by workers are, first, 'conflict' between internal workers in the experience at a day care facility for the disabled, and second, exhaustion, such as symptoms of emotional exhaustion, dehumanization, and decreased sense of accomplishment, experienced by workers in 'burnout'. It was a traumatic experience. Third, in 'growth', workers overcame internal conflict and psychological exhaustion through spirituality and experienced growth with a sense of stability. This study is expected to provide useful data to improve the morale and work environment of workers at day care facilities for the disabled in the future.

• Korean Journal of School Psychology
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• v.8 no.2
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• pp.133-152
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• 2011

This is a short-term longitudinal study investigating the relationships between changes in mental health and academic burnout among Korean middle school students. Study sample consisted of 409 middle school students in Seoul provision, with 161 male, 216 female, and 32 unidentified. Both Symptom Check List(SCL-47) and Maslach Burnout Inventory-Student Survey(MBI-SS) were used. In order to examine the pattern of changes in mental health and academic burnout among students, standardized residuals were calculated using regression equations which were then put into canonical correlation analysis. The results of this study are as follows. First, according to Function 1, among sub-factors of mental health, decreases in depression, compulsion, anxiety, and hostility were particularly associated with decreases in exhaustion and cynicism among academic burnout. Put in another way, students who showed increases in depression, compulsion, anxiety, and hostility experienced more academic exhaustion and cynicism. Second, according to Function 2, increases in phobic anxiety, compulsion with decreases in anxiety, depression were associated with decrease in academic exhaustion and increase in cynicism. Considering Russell's dimensional theory of emotion, Function 1 showed that mental health symptoms including both aroused and non-aroused affects were related with increases in exhaustion and cynicism while Function 2 showed that mental health symptoms including only aroused aspects were related with decrease in exhaustion and increase in cynicism. Thus, a conclusive intervention program seems to be required to deal with both aroused and non-aroused affects of students who are experiencing increased exhaustion and cynicism. On the other hand, an intervention program focused on aroused affects seems appropriate to students who are experiencing decreased exhaustion and increased cynicism. This study has its value in that it has enhanced understanding of students in school and counseling settings by revealing the relationships between mental health and academic burnout among adolescents and suggested differentiated intervention strategies based on patterns of students' academic burnout.

• East Asian mathematical journal
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• v.17 no.2
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• pp.319-323
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• 2001

• Textile Coloration and Finishing
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• v.15 no.6
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• pp.18-26
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• 2003

Nylon 6.6 was treated with anionic synthetic tanning agent at different pH values, temperatures and liquor ratios to determine exhaustion properties. Treatments using syntan were conducted to the undyed nylon 6.6 fiber and three acid dyeings and then samples of the bath solution were subjected to HPLC analysis. Mass analysis was considered to determine the syntan components. In addition, the effect of applications using syntan and syntan/cation in improving the stain resistance was observed. The optimum treatment condition of syntan was achieved and the major component of syntan, being exhausted to the nylon substrates, was determined. In terms of stain blocking effect, a significant improvement was achieved by the syntan and syntan/cation treatments.

• Bulletin of the Korean Mathematical Society
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• v.39 no.2
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• pp.259-267
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• 2002

Let X be a hemicompact space with ($K_{n}$) as an admissible exhaustion, and for each n $\in$ N, $A_{n}$ a Banach function algebra on $K_{n}$ with respect to $\parallel.\parallel_n$ such that $A_{n+1}\midK_{n}$$\subsetA_n$ and${\parallel}f{\mid}K_n{\parallel}_n{\leq}{\parallel}f{\parallel}_{n+1}$ for all f$\in$$A_{n+1}$, We consider the subalgebra A = { f $\in$ C(X) : $\forall_n\;{\epsilon}\;\mathbb{N}$ of C(X) as a frechet function algebra and give a result related to its spectrum when each $A_{n}$ is natural. We also show that if X is moreover noncompact, then any closed subalgebra of A cannot be topologized as a regular Frechet Q-algebra. As an application, the Lipschitzalgebra of infinitely differentiable functions is considered.d.

• Textile Coloration and Finishing
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• v.5 no.2
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• pp.117-124
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• 1993

The Silk fabric was dyed with various acid dyes, and than treated with copper sulfate or copper sulfate/thiourea. Munsell color system, dye exhaustion and light fastness were investigated for the treated fabrics. The results obtaind are as follows: 1) The color variation of the silk-dyed fabric by aftertreatment with copper sulfate was shown redish, but original color with copper sulfate/thiourea. 2) Copper sulfate/thiourea was much more effective than copper sulfate only to increase the light fastness. 3) The crease recovery was increased by aftertreatment with copper sulfate/thiourea. 4) Dye exhaustion and tensile strength of the silk-dyed fabric by aftertreatment with copper sulfate was decreased about 8-15% more than those of untreated.