• 한국잠사학회:학술대회논문집
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• 한국잠사학회 2002년도 Join Meetings of Korean Society of Sericultural Science and Japanse Society of Sericultural Science
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• pp.82-82
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• 2002

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• 과학교육연구지
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• 제40권3호
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• pp.189-202
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• 2016

이 연구는 예비과학교사들이 진화학과 유전학에 대한 학문적, 실용적 가치에 대한 인식을 조사하기 위하여 이루어졌다. 이 연구를 위하여 82명의 예비생물교사와 159명의 비생물전공 예비과학교사가 참여하였다. 5단계 리커트 척도로 된 진화와 유전에 대한 학문적 가치에 대한 4개 문항과 실용적 가치에 관한 5개 문항에 대한 응답을 수집하여 분석하였다. 문항의 타당도와 신뢰도는 내적일관성신뢰도, 이차원평정척도 라쉬모델 분석, 요인분석으로 이루어졌다. 연구 결과, 먼저 이 연구에 사용한 문항에 대한 라쉬모델 분석과 다양한 분석에서 문항의 타당도는 기준에 만족하는 것으로 확인되었다. 두 번째로 진화에 대한 학문적, 실용적 인식에 대한 차원은 유전학과 차별적인 것으로 확인되었다. 세 번째 예비생물교사가 가지는 인식의 수준은 비생물전공 예비과학교사와 차별성이 없었다. 예비생물 교사들은 진화와 유전학에 대한 학문적, 실용적 가치에 대한 이해를 높여야 함을 확인하였고, 이 연구에서 사용한 문항이 해당 구인을 조사하는데 적절하게 활용할 수 있음을 확인하였다.

• Genomics & Informatics
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• 제20권4호
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• pp.40.1-40.8
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• 2022

The concepts of phylogeny and floral genetics play a crucial role in understanding the origin and diversification of flowers in angiosperms. Angiosperms evolved a great diversity of ways to display their flowers for reproductive success with variations in floral color, size, shape, scent, arrangements, and flowering time. The various innovations in floral forms and the aggregation of flowers into different kinds of inflorescences have driven new ecological adaptations, speciation, and angiosperm diversification. Evolutionary developmental biology seeks to uncover the developmental and genetic basis underlying morphological diversification. Advances in the developmental genetics of floral display have provided a foundation for insights into the genetic basis of floral and inflorescence evolution. A number of regulatory genes controlling floral and inflorescence development have been identified in model plants such as Arabidopsis thaliana and Antirrhinum majus using forward genetics, and conserved functions of many of these genes across diverse non-model species have been revealed by reverse genetics. Transcription factors are vital elements in systems that play crucial roles in linked gene expression in the evolution and development of flowers. Therefore, we review the sex-linked genes, mostly transcription factors, associated with the complex and dynamic event of floral development and briefly discuss the sex-linked genes that have been characterized through next-generation sequencing.

• Genomics & Informatics
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• 제13권4호
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• pp.102-111
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• 2015

The karyotypes of most species of crocodilians were studied using conventional and molecular cytogenetics. These provided an important contribution of chromosomal rearrangements for the evolutionary processes of Crocodylia and Sauropsida (birds and reptiles). The karyotypic features of crocodilians contain small diploid chromosome numbers (30~42), with little interspecific variation of the chromosome arm number (fundamental number) among crocodiles (56~60). This suggested that centric fusion and/or fission events occurred in the lineage, leading to crocodilian evolution and diversity. The chromosome numbers of Alligator, Caiman, Melanosuchus, Paleosuchus, Gavialis, Tomistoma, Mecistops, and Osteolaemus were stable within each genus, whereas those of Crocodylus (crocodylians) varied within the taxa. This agreed with molecular phylogeny that suggested a highly recent radiation of Crocodylus species. Karyotype analysis also suggests the direction of molecular phylogenetic placement among Crocodylus species and their migration from the Indo-Pacific to Africa and The New World. Crocodylus species originated from an ancestor in the Indo-Pacific around 9~16 million years ago (MYA) in the mid-Miocene, with a rapid radiation and dispersion into Africa 8~12 MYA. This was followed by a trans-Atlantic dispersion to the New World between 4~8 MYA in the Pliocene. The chromosomes provided a better understanding of crocodilian evolution and diversity, which will be useful for further study of the genome evolution in Crocodylia.

• 한국미생물학회:학술대회논문집
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• 한국미생물학회 2009년도 International Meeting of the Microbiological Society of Korea
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• pp.88-89
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• 2009

• 의학교육논단
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• 제16권1호
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• pp.50-54
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• 2014

It is becoming increasingly important for medical doctors to have a thorough understanding of human genetics and the ethical, legal, and social implications of genetic testing, counseling, and treatment. As genetic engineering and technology evolves, medical doctors will find themselves called in to counsel patients about a rapidly increasing number of diseases for which genetic testing and treatments are available. Medical doctors will need to master a new set of principles and clinical skills. A lack of knowledge about these issues and problems may lead to serious, lifelong or even fatal negative effects on patients. Medical genetics has moved from the study of rare conditions to the illumination of disorders that impact the entire spectrum of medical practice. This study demonstrates several areas in which medical genetics is clearly an important tool in medical practice and the necessity of establishing new curriculum for clinical genetic education in Korea. Medical students nearing graduation may lack genetic knowledge that is essential for daily practice because genetics has little or no place in clinical teaching. Medical schools should make extensive curriculum changes to increase students' awareness of clinical genetics and its ethical implications. The medical school curriculum will need creative new approaches to keeping up with the rapid pace of evolution of clinical genetics.

• 한국과학교육학회지
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• 제14권2호
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• pp.170-183
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• 1994

In this study, in order to find our high school students' misconceptions on genetics and evolution, a free-answer form of questionnaire, specially designed through analysis of high school biology curriculum, was developed and sent to one hundred and eight high school students in Seoul area. Their responses were collected and qualitatively analyzed. Main results of the study can be summarized as follows: 1. Some students misunderstood that aquired chracters are inherited. 2. Several students weren't instructed clearly about gene. For example, they responsed that genes are not material, composed of proteins, exist only in reproductive cells and are not in plant cells at all. 3. Some students confused chromosome with chlorophyll, dorminant (in dorminant character) with excellent. They are caused by similar spells in Korean letter 4. Half students misconceptualized that organisms evolve just when their environment changes for the worse. 5. Many students believed orthogenesis.

• 한국과학교육학회지
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• 제28권2호
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• pp.120-129
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• 2008

본 연구에서는 중학교 3학년 "유전과 진화"단원 학습을 위해 만화를 활용한 형성평가 문항을 총 17개 개발하고, 이를 실험집단 73명과 통제집단 78명을 대상으로 적용하였다. 이에 학생들의 평가에 대한 인식 및 태도와 학업성취도 변화에 효과적인지를 알아보았다. 그 결과 만화를 활용한 형성평가는 학생들의 평가에 대한 부정적인 인식과 태도를 긍정적으로 변화시키는데 효과적인 것으로 나타났으며 특히, 학생들이 평가의 유용성을 인식하고(p<.05) 시험에 대한 불안감을 감소시키는 데 효과적인 것으로 나타났다(p<.01). 또한 개발된 만화를 활용한 형성평가는 서술형 지문의 형성평가에 비해 학생들의 학업성취도 향상에 긍정적인 효과를 갖는 것으로 나타났다(p<.05). 이는 "유전과 진화"단원의 추상적인 개념들을 그림으로 표현하여 학습내용과 문항의 이해를 더 쉽게 하기 때문인 것으로 판단된다. 따라서 만화를 활용한 형성평가는 학습내용의 이해와 흥미도의 향상에 기여하며 수업에 적극 활용했을 때 학생들의 평가에 대한 불안을 극복하고 평가에 대한 긍정적인 인식을 줄 수 있는 평가방법이라고 할 수 있다.

• Asian-Australasian Journal of Animal Sciences
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• 제30권7호
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• pp.912-919
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• 2017

Objective: Identification of the candidate genes that play key roles in phenotypic variations can provide new information about evolution and positive selection. Interleukin (IL)-32 is involved in many biological processes, however, its role for the immune response against various diseases in mammals is poorly understood. Therefore, the current investigation was performed for the better understanding of the molecular evolution and the positive selection of single nucleotide polymorphisms in IL-32 gene. Methods: By using fixation index ($F_{ST}$) based method, IL-32 (9375) gene was found to be outlier and under significant positive selection with the provisional combined allocation of mean heterozygosity and $F_{ST}$. Using nucleotide sequences of 11 mammalian species from National Center for Biotechnology Information database, the evolutionary selection of IL-32 gene was determined using Maximum likelihood model method, through four models (M1a, M2a, M7, and M8) in Codeml program of phylogenetic analysis by maximum liklihood. Results: IL-32 is detected under positive selection using the $F_{ST}$ simulations method. The phylogenetic tree revealed that goat IL-32 was in close resemblance with sheep IL-32. The coding nucleotide sequences were compared among 11 species and it was found that the goat IL-32 gene shared identity with sheep (96.54%), bison (91.97%), camel (58.39%), cat (56.59%), buffalo (56.50%), human (56.13%), dog (50.97%), horse (54.04%), and rabbit (53.41%) respectively. Conclusion: This study provides evidence for IL-32 gene as under significant positive selection in goat.

• 한국발생생물학회지:발생과생식
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• 제18권2호
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• pp.107-115
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• 2014

Cardiovascular system is the primary organ to develop and reach a functional state, which underscores the essential role of the vasculature in the developing embryo. The vasculature is a highly specialized organ that functions in a number of key physiological works including the carrying of oxygen and nutrients to tissues. It is closely involved in the formation of heart, and hence it is essential for survival during the hatching period. The expression of genes involved during vascular development in the olive flounder (Paralichthys olivaceus) in the days after hatching is not fully understood. Therefore, we examined the expression patterns of genes activated during the development of flounder. Microscopic observations showed that formation of blood vessels is related to the expression of the vimentin gene. Also, the temporal expression patterns of this vimentin-like gene in the developmental stages and in the normal tissues of olive flounder. The purpose of this study was to examine the expression patterns of vimentin in normal tissues of the olive flounder and during the development of the vascular system in newly hatched olive flounders and HIF-1 plays a vital role in the formation of blood vessels during development. Vimentin expression was strong at the beginning of the development of blood vessels, and was present throughout all developmental stages. Our findings have important implications with respect to the roles of vimentin and HIF-1 in the development and evolution of the first blood vessels in olive flounder. Further studies are required to elucidate the vimentin-mediated hypoxic response signal transduction and to decipher the functional role of vimentin in developmental stages.