• Title/Summary/Keyword: ether group

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A Study on Chemical Constituents and Biological Activity of Echinosophora koreensis Nakai (개느삼의 성분 및 생물활성에 관한 연구)

  • Kim, Chang-Min;Lee, Kyeong-Bok
    • Korean Journal of Pharmacognosy
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    • v.21 no.2
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    • pp.137-141
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    • 1990
  • The effects of various fractions from the aerial parts of Echinosophora koreensis Nakai on the antimutagenic and the immuno-regulating activities were evaluated by in vivo bone-marrow micronucleus test and HA titer reaction. No significant suppressive effects of these extracts and echinoisosophoranone were shown on cyclophosphamide-induced micronuclei, but HA titers were significantly enhanced in ether and BuOH extract treated-group. Tetracosanol and docosanol were isolated from the ether extract of this plant.

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A Study on Characteristics for Exhaust Emission with Oxygenated Fuel in an Agricultural DI Diesel Engine (농업용 직접분사식 디젤기관에서 함산소연료 적용시 배기배출물 특성 연구)

  • Choi, S.H.;Oh, Y.T.;So, J.D.
    • Journal of Biosystems Engineering
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    • v.32 no.5
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    • pp.279-283
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    • 2007
  • In this study, the potential possibility of oxygenates on di-ether group (DBE, dibutyl ether) was investigated as an additives for an agricultural direct injection diesel engine. It tested to estimate change of engine performance and exhaust emission characteristics for the commercial diesel fuel and oxygenates additives blending fuel which has four kinds of mixed ratio. The smoke emission of blending fuel (diesel fuel 80 vol-% + DBE 20 vol-%) was reduced in comparison with diesel fuel, that is, it was reduced approximately 26% at 2500 rpm, full load. And, power, torque and brake specific energy consumption didn't have large differences. But, NOx emission of blended fuel was increased compared with commercial diesel fuel.

The Preparation of Quaternary Ammonium Polysulfone and its Permeation Behavior (I) -Preparation of Quaternary Ammonium Polysulfone- (Quaternary Ammonium Polysulfone막의 제조 및 투과 특성 (I) - Quaternary Ammonium Polysulfone의 제조 -)

  • 현진호;전종영;김종호;탁태문
    • Membrane Journal
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    • v.6 no.2
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    • pp.72-78
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    • 1996
  • This paper was to investigate the preparation of quaternary ammonium polysulfone. The aminated polysullone (AMPS) as quaternary ammonium polysulfone was synthesized by two-step process. The first step involves the preparation of chloromethylated polysulfone (CMPS) which was produced by the introducion of chloromethyl group into polysulfone using chloromethyl methyl ether as a chloromethylation agent and zinc oxide as a catalyst. The second step, amination of CMPS was to give rise to AMPS using triethylamine.

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Study on the Chemical Properties of Korean Local Tobacco (Nicotiana tabacum L.) (한국 재래종 연초(Nicotiana tabacum L.)의 화학적 특성)

  • 김용옥;류명현;이철환;진정의
    • Journal of the Korean Society of Tobacco Science
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    • v.11 no.2
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    • pp.143-148
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    • 1989
  • Field experiment was conducted to find out the chemical characteristics of 12 Korean local varities, Local varities were compared with oriental, flue-cured and burley tobacco. Among tested varities, Hyangcho and Matskawa were desirable in respect of flavor, leaf color and texture. Hyangcho and Matskawa were higher in the content of nicotine and petroleum ether extract. Gajacho, Byeolcho and Kukjuo were higher in the content of reducing sugar, but lower nicotine, total nitrogen and petroleum ether extract. The nicotine and total nitrogen content of Kwangcho, Daruma and Catterton were lower than that of Br. 21. In the content of volatile organic acid which were major characteristic component of oriental tobacco, the Korean local varities were lower in the content of 3-methyl butanoic and 3-methyl pentanoic acid, but hirities, Hyangcho, Matskawa and Daruma were higher in the content of volatile organic acid. Korean local varities, especially small leaf group, were higher in the content of benzyl alcohol and furfural than any other type tobacco.

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Effect of Poly(ethylene glycol) dimethyl ether Plasticizer on Ionic Conductivity of Cross-Linked Poly[siloxane-g-oligo(ethylene oxide)] Solid Polymer Electrolytes

  • Kang, Yongku;Seo, Yeon-Ho;Kim, Dong-Wook;Lee, Chang-Jin
    • Macromolecular Research
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    • v.12 no.5
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    • pp.431-436
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    • 2004
  • Cross-linked network solid polymer electrolytes were prepared by means of in situ hydrosilylation between poly[hydromethylslioxane-g-oligo(ethylene oxide)] and diallyl or triallyl group-containing poly(ethylene glycols). The conductivities of the resulting polymer electrolytes were greatly enhanced upon the addition of poly(ethylene glycol) dimethyl ether (PEGDME) as an ion-conducting plasticizer. Conductivities of the cross-linked polymer electrolytes were more dependent on the molecular weight of PEGDME than on the cross-linkers. The maximum conductivity was found to be 5.6${\times}$10$\^$-4/ S/cm at 30$^{\circ}C$ for the sample containing 75 wt% of PEGDME (M$\_$n/ =400). These electrolytes exhibited electrochemical stability up to 4.5 V against the lithium reference electrode. We observed reversible electrochemical plating/stripping of lithium on the nickel electrode.

Effects of Non-Saponin Red Ginseng Components on Multi-drug Resistance

  • Kim, Eun-Hye;Park, Jong-Dae;Pyo, Suhk-Neung;Rhee, Dong-Kwon
    • Journal of Ginseng Research
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    • v.31 no.2
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    • pp.74-78
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    • 2007
  • Multi-drug resistance (MDR) is a major problem in cancer chemotherapy and has often ended up with termination of the therapy. The aim of this study was to identify any fractions of Korean red ginseng that would be effective in modulating for MDR. Although ginsenosides have been reviewed as possible MDR modulators, the MDR modulation activity of the other component is unknown. Therefore, a red ginseng was extracted with methanol, ether, ethylacetate, and n-butanol, followed by several fractionations by silica gel chromatography. And the activity of MDR modulating for these fractions was examined via sulforrhodamine B assay. We have found that several ether fractions, as nonsaponin components are effective on MDR modulation. We have expect that these results helpful to improvement of cancer chemotherapy.

Diastereoselective Synthesis of Unsaturated 1,4-Amino Alcohols as a Biologically Important Moiety

  • Jung Young Hoon;Kim Ji Duck
    • Archives of Pharmacal Research
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    • v.28 no.4
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    • pp.382-390
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    • 2005
  • chial allylic ethers with a hydroxyl group attached to the $\pi-system$ and chlorosulfonyl isocyanate. The enantioselectivity of the CSI reaction with the chiral allylic and benzylic ethers was examined in various solvents and temperatures. Based on these results, it was proposed that the CSI reaction is a competitive reaction of a $S_{N}i$ (retention) and a $S_{N}1$ mechanism (racemization) according to the stability of the carbocation intermediate. This means that there is a greater proportion of retention with the less stable the carbocation intermediate and vise versa.

Crystal Structure of Cholesteryl Methyl Ether

  • Yun, Mi-Kyung;Park, Young-Ja;Shin, Whan-Chul;Craven, B. M.
    • Bulletin of the Korean Chemical Society
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    • v.10 no.4
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    • pp.335-339
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    • 1989
  • Cholesteryl methyl ether$(CH_3OC_{27}H_{45})$ crystallizes in the monoclinic space group $P2_1$with a = 11.740 (8), b = 7.576 (5), c = 15.492 (10)${\AA},\; {\beta}\;= 110.39 (5)^{\circ}$, Z = 2, Dc = 1.03 g/$cm^3$ and Do = 0.96 g/$cm^3$. The intensities were collected on a Nonius CAD-4 diffractometer with Nb-filtered Mo-$K_{\alpha}$ radiation. The structure was solved by direct methods and refined by full matrix least-squares methods. The final R factor was 0.085 for 1479 observed reflections. Compared with other cholesterol derivatives, the cholesteryl ring and tail region of the molecule are normal. The molecular long axes are parallel to the [101] axis and molecules are packed together in a similar way to those in cholesteryl cliloride and bromide.

Characteristics of Sulfonated Poly(arylene ether sulfones) Cation-Exchange Membrane by Variation of Sulforic Acid Group Concentration (술폰화 poly(arylene ether sulfones) 양이온 교환막의 술폰산기 농도 변화에 따른 특성)

  • Kim Lae Hyun;Lee Seung Yong;Choi Sun Yong;Lee Joung Woo;Park Sei Yong
    • Journal of the Korean Electrochemical Society
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    • v.3 no.1
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    • pp.57-62
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    • 2000
  • Sulfonated Polysulfone (SPSF) cation-exchange membranes were synthesized by introducing various ratio of chlorosulfuric acid (CSA) onto the main chain of polysulfone (PSF). Properties such as ion exchange capacity, water content, liked ion concentration, and partition coefficient were measured, respectively. Through the analysis of DSC and TGA, it has been shown that glass transition temperature increased and weight loss decreased as sulfuric acid group concentration increased. Structure of membrane measured by AFM and SEM was seen to be asymmetric. Apparent diffusion coefficient of sodium ions through SPSF membrane by AC impedance was increased as sulfuric acid group concentration increased.

Serum Biochemical, Histopathology and SEM Analyses of the Effects of the Indian Traditional Herb Wattakaka Volubilis Leaf Extract on Wistar Male Rats

  • Gopal, Velmani;Mandal, Vivekananda;Tangjang, Sumpam;Mandal, Subhash C.
    • Journal of Pharmacopuncture
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    • v.17 no.1
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    • pp.13-19
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    • 2014
  • Objectives: The present study investigated the protective effect of Wattakaka (W.) volubilis leaf extract against streptozotocin (STZ)-induced diabetes in rats. Methods: Male Wistar rats were divided into five groups (with six rats in each group) and were fed ad libitum. The rats were fasted for sixteen hours before diabetes was induced by injecting a single dose of 90 mg/kg body weight of STZ in 0.9-percent normal saline through an intraperitoneal route. The five groups were as follows: Group 1: normal control (saline-treated), Group 2: untreated diabetic rats, Groups 3 and 4: diabetic rats treated orally with petroleum ether cold maceration extract (PEME) of W. volubilis (50 and 100 mg/kg body weight), and Group 5: diabetic rats treated orally with metformin (250 mg/kg body weight). All rats received treatment for 21 days. For the STZ-induced diabetic rats, the blood-glucose, ${\alpha}$-amylase, total protein and alanine transaminase (ALT) levels were measured on days 7, 14 and 21 of the treatment with PEME of W. volubilis and the treatment with metformin. Histopathological changes in the liver were examined with hematoxylin-eosin staining. Morphological changes in the liver were also examined with glutaraldehyde fixation. Results: The treatments with PEME of W. volubilis and with metformin in experimental rats by oral injections for 21 days produced reductions in the levels of serum biochemical markers. Histopathology and scanning electron microscopy results showed that the administrations of PEME of W. volubilis and of metformin suppressed the generation of abnormal liver cells in the STZ-treated rats. Conclusion: These results suggest that both PEME of W. volubilis and metformin have a protective effect against STZ-induced diabetes.