Korean Journal of Pharmacognosy (생약학회지)
- Volume 21 Issue 2
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- Pages.137-141
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- 1990
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
A Study on Chemical Constituents and Biological Activity of Echinosophora koreensis Nakai
개느삼의 성분 및 생물활성에 관한 연구
- Kim, Chang-Min (College of Pharmacy, Kang Weon National University) ;
- Lee, Kyeong-Bok (College of Pharmacy, Kang Weon National University)
- Published : 1990.06.30
Abstract
The effects of various fractions from the aerial parts of Echinosophora koreensis Nakai on the antimutagenic and the immuno-regulating activities were evaluated by in vivo bone-marrow micronucleus test and HA titer reaction. No significant suppressive effects of these extracts and echinoisosophoranone were shown on cyclophosphamide-induced micronuclei, but HA titers were significantly enhanced in ether and BuOH extract treated-group. Tetracosanol and docosanol were isolated from the ether extract of this plant.
Keywords
- Echinosophora koreensis;
- antimutagenic activity;
- haemagglutinating assay;
- HA titer;
- docosanol;
- tetracosanol;
- echinoisosophoranone