• Title/Summary/Keyword: environmental controls

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Association Study Between Genetic Polymorph isms in Interleukin-1 Gene Family and Adult Periodontitis in Korean

  • Kang, ByungYong;Kang, Chin Yang;Lee, Kang Oh
    • Toxicological Research
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    • v.20 no.4
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    • pp.299-305
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    • 2004
  • Adult periodontitis (AP) is a chronic inflammatory disease whose etiology is not well defined. Some studies suggested that the clinical characteristics of this disease may be in part explained by genetic factors, and some attempts to find genetic markers for this disease were successful. The interleukin-1 (IL-1) gene family as one of genetic factors may influence the expression of adult periodontitis. The aim of present study is to investigate the frequencies of genetic polymorphisms in the IL-1 gene family encoding three genes (IL-1A, IL-1B and IL-1RN) in Korean AP patients and periodontically healthy controls. There were no significant differences in genotype and allele frequencies of these polymorph isms between two groups, respectively. However, -511 polymorphism of IL-1 B gene was significantly associated with mean pocket depth (MPD, mm) value in AP patients (P<0.05). Therefore, our results suggest that -511 polymorphism in the IL-1B gene may be useful as a genetic marker for the severity of AP in Koreans.

Regulatory roles of NKT cells in Anaplasma phagocytophilum infection

  • Choi, Kyoung-Seong;Chae, Joon-Seok
    • Korean Journal of Veterinary Research
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    • v.49 no.2
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    • pp.167-172
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    • 2009
  • Human granulocytic anaplasmosis (HGA) is caused by the obligate intracellular bacterium Anaplasma (A.) phagocytophilum. Natural killer T (NKT) cells are key players in host defense against various microbial infections. We investigated the role of NKT cells in immune response to A. phagocytophilum infection using NKT-knockout ($J\alpha$18-/-) mice. $J\alpha$18-/- and wild-type (WT) mice were infected with low-passage A. phagocytophilum and assayed for hepatic histopathology and cytokine production during 7 days post-infection. Compared to WT controls, the infected $J\alpha$18 -/- mice had much less histopathologic lesions and less apoptosis through day 7, and lower concentrations of ${IFN\gamma}$ and IL- 12, but not of IL-10. This result suggests that NKT cells are major components in the pathogenesis of HGA.

A Study on Temperature Characteristics of Electric Apparatuses for High Speed Train (고속철도차량용 전기장치의 온도특성에 관한 연구)

  • 한영재;양도철;장호성;최종선;김정수
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.16 no.12S
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    • pp.1210-1216
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    • 2003
  • Recently, as the road capacity reaches the limit and environmental problems becomes serious, there is gradually increased a need for railroad vehicles that are environment-friendly and have time regularity, reliability, and safety. Accordingly, in addition to conventional railroad vehicles, lots of vehicles are being newly developed. We developed the hardware and software of the measurement system for on-line test and evaluation of korean high speed train. The software controls the hardware of the measurement system and acts as interface between users and the system hardware. In this paper, practical experiment are performed to verify mechanical performance of motor and main transformer for Korean high speed rail. The experimental test carried out by using new temperature measurement method and verify the temperature performance of motor and transformer is verified.

FSP measurement of heat-treated softwoods using volumetric swelling method (부피팽창율법을 이용한 침엽수 열처리 목재의 섬유포화점 측정)

  • Kang, Chun-Won;Lee, Seung-Jin;Kang, Ho-Yang
    • Korean Journal of Agricultural Science
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    • v.39 no.2
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    • pp.183-187
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    • 2012
  • Specimens of five softwood species were heat-treated at three temperature levels of $170^{\circ}C$, $190^{\circ}C$ and $210^{\circ}C$. Their FSP's were measured by the volumetric Swelling Method. Within a species the FSP decreases as the temperature of heat treatment increases. The FSP's of the controls range from 21.0% to 32.5%, while those of the specimens heat-treated at $210^{\circ}C$ from 18.7% to 35.3%. There was no difference of basic density between the heat-treated and control specimens.

Overriding Photoperiod Sensitivity of Flowering Time by Constitutive Expression of a MADS Box Gene

  • N, Gynheung-A
    • Proceedings of the Botanical Society of Korea Conference
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    • 1996.07a
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    • pp.4-9
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    • 1996
  • The majority of plants sense environmental signals, such as day length or temperature, to select their transition timing from vegetative growth t flowering. Here, we report the identification of a regulatory gene, OsMADS1, that controls the photoperiod sensitivity of flowering time. Constitutive expression of OsMADS1 in a long-day flowering plant, Nicotiana sylvestris, resulted in flowering in both short-day long-day conditions. Similarly, ectopic expression of the gene in a short-day flowering plant, N. tabacum cv. Maryland Mammoth, also induced flowering regardless of the day length. The transition time was dependent on the level of the OsMADS1 transcript in transgenic plants. These suggest that OsMADS1 is a key regulatory factor that determines the transition from shoot apex to floral meristem and that it can be used for controlling flowering time in a variety of plant species.

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Genetic Polymorphism of Vascular Endothelial Growth Factor (VEGF C936T) in the Korean Population

  • Kim, Jin-Kyeoung;Oh, Do-Yeun;Kwak, Sun-Young;Han, Jin-Hee;Chung, Young-Sun;Kim, Nam-Keun
    • Animal cells and systems
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    • v.7 no.3
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    • pp.261-264
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    • 2003
  • Leiden), no mutation was detected in either group. Allele frequencies of A2379G and G2391 A mutations were not significantly different between CAD patients and controls. Non-Caucasian populations have a considerably lower factor Ⅴ Leiden allele frequency than Caucasian populations. Thus, it may be due to differences in the genetic background as well as environmental factors.

Decay Resistance of Borate-Modified Oriented Strandboard: A Comparison of Zinc and Calcium Borate

  • Lee, Sun-Young;WU, Qinglin
    • Journal of the Korean Wood Science and Technology
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    • v.36 no.5
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    • pp.1-10
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    • 2008
  • Decay and mold resistance of zinc borate (ZB) and calcium borate (CB) modified oriented strandboard (OSB) from southern mixed hardwood and southern yellow pine was investigated in this study. Brown rot fungus Gloeophyllum trabeum and white-rot fungus Trametes versicolar were used to examine the decay resistance of the OSB. The OSB test specimens were colonized by brown and white rot fungal mycelium in both the brown and white-rot culture bottles after 8 and 12 weeks, respectively. The wood species and fungus type had the significant effects on the decay resistance. Brown rot decay was evident for all untreated southern pine and mixed hardwood controls. The white-rot decay, however, did not show significant weight loss at both species control samples. The incorporation of ZB and CB composites provides suitable protection against brown-and white-rot fungi. No significant weight loss was observed from the borate treated OSB.

Development of reliability test to reduce the field failure rate of PC Monitor (PC 모니터의 시장불량률 감소를 위한 신뢰성 시험법 개발)

  • 김준홍
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.24 no.67
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    • pp.69-76
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    • 2001
  • In order to review the failure rate of PC monitor under normal environmental conditions, we experimented for various levels of each factors, e.g. Power on/off, DPM mode, using voltage incoming Surge, Torque strength etc. According to the results of experiment and SN ratios we investigated that the causes of the failure for the horizontal output TR of monitor are Mode change, dispersion of Torque and $h_{FE}$ and these are critical effect. For the new reliability test we suggested that strengthened part tests in IQC branch, Torque change controls in the TR specification are necessary.

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Case Study on Improvement of Reliability Prediction Accuracy in Development Phase for Aircraft (항공기 개발단계에서의 신뢰도 예측 정확도 향상에 관한 사례연구)

  • Kim, Young-Il;Byun, Kwang-Sik;Kim, Han-Tai
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.17 no.4
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    • pp.25-31
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    • 2009
  • In development phase of the Aircraft Systems, the reliability prediction of electronic equipments are usually performed using MIL-HDBK-217. The reliability of fielded electronic systems, however, used to be underestimated with MIL-HDBK-217. To solve this problem, some alternatives are suggested and Telcordia SR-332 is among them. In this case study, the reliability of ESU which controls gas turbine engine is predicted using Telcordia SR-332 along with the development test data. The predicted reliabilities of ESU using Telcordia SR-332 and MIL-HDBK-217 are also compared. As a result this case study showed that the predicted reliability using Telcordia SR-332 was better close to field(operation) reliability than MIL-HDBK-217.

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섬유질유물의 포화(Degradation)에 영향을 주는 요인들에 대한 연구

  • Bae, Sang-Gyeong
    • 보존과학연구
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    • s.11
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    • pp.1-9
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    • 1990
  • The environmental controls for good conservation of all textile materials are follow as :1) Special RH conditions on textiles keep to the usually advocated 50∼55%.2) The effect of the temperature is too small to worry about in the applicable range, that is $20^{\circ}C$.3) It is important to keep soiling by air borne dirt to a minimum by an air filter or putting textiles in cases.4) Sulphur dioxide must be rekoved by an activated carbon filter or a water spray. And this concentration below $50\muGm^3$ can be regarded assatisfactory.5) Oxygen plays a part of deterioration proceses. The effect of nitrogend andinert gases in sealed show cases should be further studied.6) Ozone is detrimental to textiles. It can be removed by activated carbonfilter.7) The removal of UV radiation and blue light can be expected to increase the lifetime of dyeing and strength of fiber.50 lux is suggested for sensitive textile materials.

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