• The Korean Journal of Physiology and Pharmacology
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• 제3권1호
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• pp.29-34
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• 1999

The hyperactivity of cholinergic system in the RVLM of spontaneously hypertensive rats (SHR) may contribute to the sustained elevation of blood pressure. However, the hyperactivity mechanisms of cholinergic system are controversial. Thus, to clarify the mechanisms of cholinergic hyperactivity in RVLM of the SHR, we studied the activities of enzymes that participate in the biosynthesis and degradation of acetylcholine (ACh) and the density of muscarinic receptors in RVLM of the 14- to 18-week-old SHR and age-marched Wistar Kyoto rats (WKY). Choline acetyltransferase activity was far greater in RVLM of SHR than that of WKY. $[^3H]ACh$ release from RVLM was also greater in SHR than in WKY. Acetylcholinesterase activity and $[^3H]NMS$ binding of RVLM slice of SHR were not significantly different from that of WKY. These results suggest that the enhanced cholinergic mechanisms in the RVLM of SHR is due to the enhanced presynaptic cholinergic tone rather than the altered postsynaptic mechanisms.

• ETRI Journal
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• 제37권3호
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• pp.637-645
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• 2015

Common-mode noise (CMN) is an unresolved problem in wireless capsule endoscopy (WCE) systems. In a WCE system, CMN originates from various electric currents found within the human body or external interference sources and causes critical demodulation performance degradation. The differential operation, a typical method for the removal of CMN rejection, can remove CMN by subtracting two signals simultaneously received by two reception sensors attached to a human body. However, when there is impedance mismatching between the two reception sensors, the differential operation method cannot completely remove CMN. Therefore, to overcome this problem, we propose an enhanced CMN rejection method. The proposed method performs not only subtraction but also addition between two received signals. Then a CMN ratio can be estimated by sufficient accumulation of division operation outcomes between the subtraction and addition outputs during the guard period. Finally, we can reject the residual CMN by combining the subtraction and addition outputs.

• Journal of Pharmaceutical Investigation
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• 제23권4호
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• pp.187-206
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• 1993

Since the advent of recombinant DNA technology coupled with other biotechnology a variety of therapeutically effective proteins and peptides have been extensively invesitigated and many of them are now on clinical trial. They, however, suffer from some problems such as immunogenicity, antigenicity, instability and short half-life in circulation due to their proteinous natures. These drawbacks can be overcome successfully by conjugating proteins and peptides with hydrophilic polymers such as polyethylene glycol (PEG), albumin or dextran. The resulting soluble conjugates showed reduced antigenicity and immunogenicity, increased circulatory half-life, enhanced stability against proteolytic degradation. Comparing with the unmodified proteins and peptides, the therapeutic potential of conjugates is greatly enhanced. Clinical applications of these conjugates have shown promising results for the future use.

• Coupled systems mechanics
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• 제3권1호
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• pp.111-145
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• 2014

In this paper we present a new model for computing the nonlinear response of reinforced concrete frame systems subjected to extreme thermomechanical loads. The first main feature of the model is its ability to account for both bending and shear failure of the reinforced concrete composites within frame-like model. The second prominent feature concerns the model capability to represent the total degradation of the material properties due to high temperature and the thermal deformations. Several numerical simulations are given to confirm these capabilities and illustrate a very satisfying model performance.

• KSBB Journal
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• 제15권4호
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• pp.393-397
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• 2000

The cometaboic biodegradation conditionso f trichloroethylene(TCE) by Burkholderia cepacia G4 were optimized using response surface analysis. The experimental sets of phenol concentration temperature and pH were designed using central composite experimental design. The optimal conditions of phenol concentration temperature and pH were determined to be 0.91 ppm 21.5$^{\circ}C$ and 7.65 respectively by the Ridge analysis of the contour plot for TCE biodegradation rates. The TCE biodegradation rate could be enhanced up to 2.43 nmol.mg protein$.$min by response surface methodology.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2002년도 하계학술대회 논문집
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• pp.89-93
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• 2002

In the present paper we suggested a parallel-branch structure of aluminum spiral inductor for the use of RF integrated circuit at 1∼3 GHz. The inductor was implemented on P-type silicon wafer (5∼15 Ω-cm) under the standard CMOS process and it showed a improved quality(Q) factor by more than 10% with no degradation of inductance. The effect of the structure modification on the Q factor and the inductance was scrutinized comparing with those of the conventional spiral inductors.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2003년도 하계종합학술대회 논문집 Ⅳ
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• pp.1803-1806
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• 2003

This paper presents a H/W module that executes a fragile watermarking algorithm. The module inputs sequentially quantized DCT values, encodes watermark and then outputs watermarked DCT coefficients. A fragile and invisible watermarking algorithm is adopted, modified and enhanced here to reduce H/W size and image degradation. The module can be directly inserted between DCT quantizer and VLC encoder in wide spread JPEG/MPEG encoder. The module is expected to be used for real-time authentication purpose in DVR(Digital Video Recorder) or digital cameras.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
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• pp.391-391
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• 2000

Manufacturing process generally exhibits major or minor variations due to deviation of raw materials, equipment degradation, controller malfunction, and so on. Extensive research based on multivariate statistical process control has been done to monitor the unstable states and indicate a corrective action. A prototype of intelligent operation support system ("ISYS-MSPC") has been developed as a tool that supports the enhanced operation to guarantee the high productivity and a uniform high quality product. This system has been applied to the industrial batch and continuous processes and its performance has been validated .

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2006년도 하계종합학술대회
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• pp.101-102
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• 2006

Similar to Orthogonal Frequency Division Multiplexing (OFDM), a Single Carrier with Frequency Domain Equalization (SC-FDE) system is computationally efficient since equalization is performed on a block of data in the frequency domain. In coherent QAM schemes, the mean phase rotation error caused by the residual carrier frequency offset may lead to serious degradation. When the frequency equalizer is combined with the mean phase error tracking algorithm, its performance can be enhanced noticeably.

• 대한화학회지
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• 제67권3호
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• pp.199-203
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• 2023