• Title/Summary/Keyword: endogenous factors

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Production of an Acidic Polygalacturonase from Aspergillus kawachii by Solid State Fermentation and Their Application for Pectin Extraction

  • Martinez-Avila, Guillermo Cristian Guadalupe;Wicker, Louise;Aguilar, Cristobal Noe;Rodriguez-Herrera, Raul;Contreras-Esquivel, Juan Carlos
    • Food Science and Biotechnology
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    • v.18 no.3
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    • pp.732-738
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    • 2009
  • An acidic polygalacturonase (PG) from Aspergillus kawachii was produced by solid state fermentation employing a polyurethane foam support. The conditions used for the production of acidic PG were particle size of support (0.6 or 500 $mm^3$) and fermentation time. From the factors studied, the particle size had important influence on enzyme production. The best conditions for acidic PG production were $0.6\;mm^3$ particle size, 18 hr at $30^{\circ}C$ and initial pH of 5.0. In addition, pectin was extracted from citrus pomaces (grapefruit, lime, and tangerine) by acidic PG at $50^{\circ}C$ for 24 hr with citric acid solution. Infrared spectroscopy showed that lime pomace had more high-methoxylated (65%) endogenous pectin than was obtained than from grapefruit or tangerine pomaces. The enzymatically extracted pectin yield in dry basis (d.b.) for grapefruit and lime pectins were 6.95 and 4.25%, respectively. The citric acid solution alone also contributed to pectin extraction from citrus pomaces (7-9%, d.b.). Limited pectin extraction by acidic PG from tangerine pomace was most likely due to the presence of low-methoxylated endogenous pectin. The enzymatic method for pectin extraction using acidic PG from A. kawachii is a promising technique for releasing highly polymerized pectic substances from high-methoxylated lime or grapefruit pomaces.

Measuring Korea's Industry-level Productivity Change Due to Tariff Cuts using a CGE Model

  • Roh, Jaewhak;Roh, Jaeyoun
    • Journal of Korea Trade
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    • v.25 no.3
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    • pp.48-64
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    • 2021
  • Purpose - This study examined the effect of tariff cuts on productivity in Korea's manufacturing industries and the effect of initial productivity level before tariff cuts on productivity improvement after tariff cuts. We also attempted to identify whether import-driven or export-driven factors are more important for productivity improvement, especially in low productivity industries. Design/methodology - Since tariff reduction is a policy decision that can affect cross-industry, its impact is spread across all industries beyond the scope of a single firm through the input and output network of industry structure. Accordingly, we proposed a new method to measure the change in productivity to reflect the impact of tariff cuts across industries. Through an Armington CGE analysis, changes in endogenous variables can be directly measured after the exogenous shock of tariff reduction, and the amount of movements in productivity triggered by tariff cuts can also be calculated. We can thus assess the effectiveness of exogenous policy, such as tariff cuts, through the difference between the benchmark and counterfactual values of endogenous variables. Findings - This study confirmed that tariff reduction positively affected productivity improvement in Korea's manufacturing industries. It also confirmed that productivity gains occur in Korea's leading export industries. Finally, greater productivity gains were recorded in the group with additional high-export-share or high-import-share conditions for low productivity industries. These results are, in a limited sense, consistent with the existing studies that emphasize the importance of exports and imports on productivity improvement, especially for low productivity industries. Originality/value - The results of our experiments are different from those of non-CGE studies, which measure the industry-level change in productivity with dummy coefficients, in terms of directly calculating the amount of change in productivity. In addition, we propose that the Armington CGE model is more appropriate than the Melitz CGE model to directly measure the productivity after tariff cuts. This is because the Melitz CGE model assumes the given specific productivity density, which does not change after an overall drop of tariffs. To the best of our knowledge, this approach to directly calculating productivity by reflecting the impact of tariff reduction across industries through CGE analysis, is unprecedented in this literature.

The effect of subjective perception on preference for the universality of the welfare system: the approach using instrument variables (개인의 주관적 인식이 복지제도의 보편성에 대한 선호에 미치는 효과: 도구변수를 활용한 접근법)

  • Kim, Sa-Hyun
    • Korean Journal of Social Welfare Studies
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    • v.41 no.3
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    • pp.213-239
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    • 2010
  • The purpose of this research is to explore the explanatory factors of preference for the universality of the welfare system at the time of expanding the welfare system. In particular, considering endogenous problem that may occur in the process of analyzing the causal relationship between subjective perception and preference for welfare policy, the 2SLS regression analysis using instrument variables was attempted in this research. The key findings of this research were as follow. First, the groups who are opposed to the welfare state expansion, for example high income earners, low risk group, and employer/self-employer, prefer the more universal welfare systems. Second, the negative perception of welfare policy and recipients, which is stronger in older generation who experienced a much longer period of industrializaion, have a negative effect on preference for the universal welfare system. Last, we find that the endogenous problem arise in this research and distort the estimated regression coefficients. Therefore, subsequent studies must be mindful of this problem when they explain attitudes with attitudes.

Effects of Constitutive Androstane Receptor (CAR) on PBRU Transactivation of CYP2B Gene in Different Culture Cell Types: Comparison Between Hep G2 and COS-cells (배양세포의 Type에 따른 Constitutive Androstane 수용체 (CAR)의 CYP2B PBRU 전사활성 효과: Hep G2와 COS 세포의 비교)

  • 민계식
    • Journal of Life Science
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    • v.13 no.3
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    • pp.324-332
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    • 2003
  • The objective of this study was to examine if transient transfection of CAR can transactivate CYP2B1 PBRU reporter gene in COS cells in which the endogenous CYP2B1 gene is not induced by PB. In non-transfeced cells of both Hep G2 and COS, the endogeneous expression of CAR was not detected by antibody against CAR. When cultured cells were transfected with CAR expression plasmid, mCAR1-GFP, both cell types expressed high levels of CAR protein and could allow to examine the effect of CAR in PBRU transactivation. Both cell types expressed endogenous RXR and transfection of RXR expression plasmid dramatically increased its protein expression. Whereas CAR transactivated PBRU2C1Luciferase about 12 fold as compared to 2C1Luciferase in Hep G2 cells, it did not stimulate the luciferase activity of the PBRU reporter gene in COS cells. These results indicate that Hep G2 cells can respond to CAR differently from COS cells, and suggest that factors other than CAR and RXR may be required in inducing PBRU activation and the expression of these factors may be different between liver and kidney.

A Investigation into Arrhythmia between East and West medicine (부정맥(不整脈)에 대(對)한 동서의학적(東西醫學的) 문헌고찰(文獻考察))

  • Jeong, Gwang-Sik;Kim, Young-Guen;Kwon, Jung-Nam;Kim, Kyoung-Min
    • The Journal of Internal Korean Medicine
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    • v.21 no.5
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    • pp.747-763
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    • 2000
  • through a literal study upon Arrhythmia between east and west medicine, the results were as follows 1. Arrhythmia is not only irregular cardiac beat but disorder of cardiac impulse making and conduction disturbance. it means almost irregularity of interval between two beat 2. In the east medicine, arrhythmia is represented various category as palpitation, continuous palpitation, dizziness, consumption which give the first consideration by the accompanied symptoms. A separate way in a diagnostics it become a base of diagnosis of diseases and decision of prognosis by the examination of pulse 3. In the west medicine, Arrhythmia is classified as disorder of heart rate, rhythm, conduction disturbance or tachycardia, bradycardia and it is concomitant with fatigue, palpitation, dyspnoea, syncope, chest discomfort 4. The diagnostic study of pulse condition which represent arrhythmia was started from $\mathbb{<}$Nae-Kyung$\mathbb{>}$ and it was revealed as pulse condition of rapid pulse, slow pulse, swift pulse, running pulse, knotted pulse, intermittent pulse etc. Out of them running pulse, knotted pulse, intermittent pulse which obviously are concomitant with irregularity of interval are clinically meaningful in a conditions of disease and decision of prognosis. and the significance of these pulse condition are transformed through the changes of the times 5. According to cause of disease it is classified by Arrhythmia(running pulse, knotted pulse, intermittent pulse) due to heat, cold, phlegm, deficiency(or insufficiency) and There are three categories of etiological factor that is, endogenous, exogenous and non-exo-endogenous factor. the endogenous factor is insufficiency of the heart Ki, deficiency of both Ki and blood, intemal stagnation of phlegm and fluid, stagnation of seven emotions. the exogenous factor is caused by stagnation of Ki and blood by six exogenous pathogenic factor and the non-exo-endgenous factors are improper diet, overstrain, traumatic injury. A cause of arrhythmia in western medicine are a organic and pathological change of the heart itself and malfunction of the autonomic nervous system.

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A study on the psychological well-being of the parents of the adult intellectual disabilities - on the fucus of gender differences. (성인 지적장애인 아버지와 어머니의 심리적 안녕감 설명모형 연구)

  • Yoo, Yong-Shik;Roh, Seung-Hyun
    • Korean Journal of Social Welfare Studies
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    • v.41 no.4
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    • pp.247-276
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    • 2010
  • This study aimed to examine the model to explain the mediator effect of care evaluation(care stress, care satisfaction) on the effect of stress factors and resource on the psychological well-being of the parents of the adult intellectual disabilities. Examining whether there is a difference between the gender of parents was another aim of this study. Study results showed that with the care stress as an endogenous variable, the daily life function and maladjustment behavior of adult children and the health state of parents had a significant direct effect on the psychological well-being of parents. With care satisfaction as an endogenous variable, family support, expert support and care stress had a significant direct effect. With the psychological well-being as an endogenous variable, care satisfaction and care stress had a significant effect, but the health state of parents didn't. In case of indirect effect, the care stress had a significant mediator effect on the effect of the physical function and maladjustment behavior of adult children and the health state of parents on the psychological well-being of parents. Care satisfaction had a significant mediator effect on the effect of family support, expert support and care stress on the psychological well-being of parents. According to the result of the Multiple Group Analysis, the path showed a statistically significant difference between gender was friend support→care satisfaction, care stress→psychological wellbeing, expert support→care satisfaction. On the basis of the study results, practical suggestions were made.

Challenges to Prevent in Practice for Effective Cost and Time Control of Construction Projects

  • Olawale, Yakubu A.
    • Journal of Construction Engineering and Project Management
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    • v.10 no.1
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    • pp.16-32
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    • 2020
  • Cost and time control of projects is important in preventing project failure. However, achieving effective cost and time control in practice is often challenging. The challenges of project cost and time control in practice are investigated by carrying out a questionnaire survey on the top 150 construction contractors in the UK followed by in-depth semi-structured interviews of practitioners from 15 construction companies in the country. Quantitative analysis reveals that design change is the most important factor inhibiting the ability of UK contractors from effectively controlling both the cost and time of construction projects. Four of the top five factors inhibiting effective cost control are also the top factors inhibiting effective time control albeit in a different order. These top factors-design changes, inaccurate evaluation of project time/duration, risk and uncertainty, non-performance of subcontractors and nominated suppliers were also found to be endogenous factors to the project. Additionally, qualitative analysis of the interviews reveals 16 key challenges to prevent for effective project cost and time control in practice. These are classified into four categorised based on where they stem from as follows; from the organisation (1. Lack of integration of cost and time during project control, 2. lack of management buy-in, 3. complicated project control systems and processes, 4. lack of a project control training regime); from the construction management/project management approach (5. Lapses in integration of interfaces, 6. project control not being implemented from the early stages of a project, 7. inefficient utilisation and control of labour, 8. limited time devoted to planning how a project will be controlled at the outset); from the client; (9. Excessive authorisation gates, 10. use of adversarial and non-collaborative forms of contracts, 11. communication problems within client set-up, 12. obstructive client representatives) and; from the project team (13. Lack of detailed/complete design, 14. lack of trust among the project partners, 15. limited time devoted to project control on site, 16. non-factual reporting). The study posits that knowledge of these project control inhibiting factors and challenges is the first step at ensuring they are avoided and enable the implementation of a more effective project cost and time control process in practice.

Methods for Determination of Amino Acids Bioavailability in Pigs - Review -

  • Zebrowska, T.;Buraczewski, S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.11 no.5
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    • pp.620-633
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    • 1998
  • Methods developed for measuring digestibility and availability of amino acids in feedstuffs used in pig nutrition are reviewed. Digestibility is a proportion of an amino acid in a feed that is absorbed from the digestive tract and should be determined from the difference between the amount of amino acid consumed and passing the distal ileum. Techniques for ileal digesta sampling including various types of cannulas: a re-entrant, T-piece, IPV, IPVC and ileaorectal anastomosis are described and comparisons amongst these methods are presented. Other methodologies like mobile bag technique, in vitro assays and mathematical prediction method are also described. Significance and methodologies for measurement of endogenous nitrogen and amino acids losses at the distal ileum and their effect on the apparent and true nitrogen and amino acid digestibilities in feeds are discussed. Factors influencing the apparent and true amino acid digestibilities such as dry matter intake, protein, fibre and antinutritive compounds content in the diet are discussed. Amino acid bioavailability -the proportion of the total amino acid digested and absorbed in a form utilized in metabolism - measured by the growth assay may differ from its ileal digestibility. Chemical methods for determination of available lysine content in heat treated feeds are evaluated.

Fall Prediction Model for Community-dwelling Elders based on Gender (지역사회 노인의 성별에 따른 낙상 예측모형)

  • Yun, Eun Suk
    • Journal of Korean Academy of Nursing
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    • v.42 no.6
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    • pp.810-818
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    • 2012
  • Purpose: This study was done to explore factors relating to number of falls among community-dwelling elders, based on gender. Methods: Participants were 403 older community dwellers (male=206, female=197) aged 60 or above. In this study, 8 variables were identified as predictive factors that can result in an elderly person falling and as such, supports previous studies. The 8 variables were categorized as, exogenous variables; perceived health status, somatization, depression, physical performance, and cognitive state, and endogenous variables; fear of falling, ADL & IADL and frequency of falls. Results: For men, ability to perform ADL & IADL (${\beta}_{32}$=1.84, p<.001) accounted for 16% of the variance in the number of falls. For women, fear of falling (${\beta}_{31}$=0.14, p<.05) and ability to perform ADL & IADL (${\beta}_{32}$=1.01, p<.001) significantly contributed to the number of falls, accounting for 15% of the variance in the number of falls. Conclusion: The findings from this study confirm the gender-based fall prediction model as comprehensive in relation to community-dwelling elders. The fall prediction model can effectively contribute to future studies in developing fall prediction and intervention programs.

Light-Dark and Food Restriction Cycles in Red sea bream, Pagrus major: Effect of Zeitgebers on Demand-feeding Rhythms

  • Choe Yong-Gwon;Choi Jae-Eun;Roh Duk-Whan;Bae Bong-Seong;Choi Cheol-Young
    • Fisheries and Aquatic Sciences
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    • v.4 no.3
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    • pp.138-143
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    • 2001
  • Red sea bream, Pagrus major a fish species characterized by its dualistic feeding pattern, was investigated to study the synchronizing effect of light and food on the demand-feeding rhythm. Nocturnal and diurnal red sea bream, both in groups and individually, were exposed to restricted-feeding and Light-Dark cycles of different periods. The phase relationship between both zeitgebers was also studied. In some cases, food availability restricted to the light or dark phase contrary to that of the previous feeding phase changed a diurnal feeding pattern into nocturnal and vice versa, suggesting that food can be one of the switching factors that decides whether the circadian system of red sea bream is diurnal or nocturnal. However, the fact that the feeding pattern of some fish was unrelated with the phase in which food was available suggests that other internal and/or external-factors could be involved in the temporal flexibility of red sea bream.

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