1 |
Wei, P., J. Zhang, M. Egan-Hafley, S. Liang and D. D. Moore. 2000. The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism. Nature. 407, 920-923
DOI
ScienceOn
|
2 |
Sueyoshi, T., T. Kawamoto, I. Zelko, P. Honkakoski and M. Negishi. 1999. The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene. J. Biol. Chem. 274, 6043-6046
DOI
ScienceOn
|
3 |
Sueyoshi, T. and M. Negishi. 2001. Phenobarbital response elements of cytochrome P450 genes and nuclear receptors. Annu. Rev. Pharmacol. Toxicol. 41, 123-143
DOI
ScienceOn
|
4 |
Suwa, Y, Y Mizukami, K. Sogawa and Y. FujiiKuriyama. 1985. Gene structure of a major form of phenobarbital-inducible cytochrome P-450 in rat liver. J. Biol. Chem. 260, 7980-7984
|
5 |
Trottier, E., A. Belzil, C. Stoltz and A. Anderson. 1995. Localization of a phenobarbital-responsive el-ement (PBRE) in the 5'-flanking region of the rat CYP2B2 gene. Gene 158, 263-268
DOI
ScienceOn
|
6 |
Tzameli, I., P. Pissios, E. G. Schuetz and D. D. Moore. 2000. The xenobiotic compound 1,4-bis[2-(3,5dichloropyridyloxy)] benzene is an agonist ligand for the nuclear receptor CAR. Mol. Cell Bioi. 20, 2951-2958
DOI
ScienceOn
|
7 |
Waxman, D. J. 1999. P450 gene induction by struc-turally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR. Archives of Biochemistry and Biophysics 369, 11-23
DOI
ScienceOn
|
8 |
Waxman, D. J. and L. Azaroff. 1992. Phenobarbital induction of cytochrome P-450 gene expression. Biochem. J. 281, 577-592
|
9 |
Negishi, M. and T. Sueyoshi. 2001. Phenobarbital response elements of Cytochrome P450 genes and nuclear receptors. Annu. Rev. Pharmacol. Toxicol. 41,123-143
DOI
ScienceOn
|
10 |
Park, Y., H. Li and B. Kemper. 1996. Phenobarbital induction mediated by a distal CYP2B2 sequence in rat liver transiently transfected in situ. J. Biol. Chem. 271, 23725-23728
DOI
ScienceOn
|
11 |
Ramsden, R., N. B. Beck, K. M. Sommer and C. J. Omiecinski. 1999. Phenobarbital responsiveness con-ferred by the 5-flanking region of the rat CYP2B2 gene in transgenic mice. Gene. 228, 169-179
DOI
ScienceOn
|
12 |
Ramsden, R., K. M. Sommer and C. J. Omiecinski. 1993. Phenobarbital induction and tissue-specific ex-pression of the rat CYP2B2 gene in transgenic mice. J. BioI. Chem. 268, 21722-21726
|
13 |
Savas, U., K. J. Griffin and E. F. Johnson. 1999. Molecular mechanisms of cytochrome P-450 induction by xenobiotics: An expanded role for nuclear hormone receptors. Molecular Pharmacology. 56, 851-857
|
14 |
Shervington, A. 1999. CYP2B2 gene expression and phenobarbital induction in kidneys using an in vitro transcription system. Biochem. Mol. BioI. Int. 47, 233-237
|
15 |
Min, G., J. K. Kemper and B. Kemper. 2002. Glucocorticoid receptor-interacting protein 1 mediates ligand-independent nuclear translocation and activation of constitutive androstane receptor in uiuo. J. BioI. Chem. 277, 26356-26363
DOI
ScienceOn
|
16 |
Strobel, H. W., A. Y H. Lu, J. Heidma and M. J. Coon. 1970. Phosphotidylcholine requirement in the enzymatic reduction of hemoprotein P-450 and in fatty acid, hydrocarbon, and drug hydroxylation. J. Biol. Chem. 245, 4851-4954
|
17 |
Kim, J., I. Rivera-Rivera and B. Kemper. 2000. Tissue-specific chromatin structure of the CYP2B1 phenobar-bital-responsive unit and proximal promotor and modulation by phenobarbital. Nucleic Acids Res. 28, 1126-1132
DOI
ScienceOn
|
18 |
Liu, S., Y. Park, I. Rivera-Rivera, H. Li and B. Kemper. 1998. Nuclear factor-1 motif and redundant regulatory elements comprise phenobarbital-responsive enhancer in CYP2B1/2. DNA Cell Bioi. 17, 461-470
DOI
ScienceOn
|
19 |
Moore, D. and I. Tzameli. 2001. Role reversal: new insights from new ligands for the xenobiotic receptor CAR. TRENDS in Endocrinology and Metabolism 12, 7-10
DOI
ScienceOn
|
20 |
Moore, L. B., D. J. Parks, S. A. Jones, R. K. Bledsoe, T. G. Consler, J. B. Stimmel, B. Goodwin, C. Liddle, S. G. Blanchard, T. M. Willson, J. L. Collins and S. A. Kliewer. 2000. Orphan nuclear receptors con-stitutive androstane receptor and pregnene X receptor share xenobiotic and steroid ligands. J. Biol. Chern. 275, 15122-15127
DOI
ScienceOn
|
21 |
Mueller, G. C. and J. A. Miller. 1949. The reductive cleavage of 4-demethylaminoazobenzene by rat liver: The intracellular distribution of the enzyme system and the requirement for triphosphopyridine nucleotide. J. BioI. Chem. 180, 1125-1136
|
22 |
Negishi, M. and P. Honkakoski. 2000. Regulation of cytochrome P450 (CYP) genes by nuclear receptors. Biochem. J. 347, 321-337
DOI
ScienceOn
|
23 |
Kim, J. and B. Kemper. 1997. Phenobarbital alters protein binding to the CYP2Bl/2 phenobarbital-responsive unit in native chromatin. J. Bioi. Chem. 272, 29423-29426
DOI
ScienceOn
|
24 |
Jean, A., A. Reiss, M. Desrochers, S. Dubois, E. Trottier, Y. Trottier, L. Wirtanen, M. Adesnik, D. J. Waxman and A. Anderson. 1994. Rat liver cyto-chrome P450 2B3: structure of the CYP2B3 gene and immunological identification of a constitutive P450 2B3-like protein in rat liver. DNA Cell BioI. 13, 781-792
DOI
ScienceOn
|
25 |
Johnson, E. F., K. J. Griffin and U. S. Keith. 1999. Molecular mechanisms of cytochrome P-450 induction by xenobiotics: An expanded role for nuclear hormone receptors. Molecular Pharmacology. 56, 851-857
|
26 |
Kawamoto, T., T. Sueyoshi, I. Zelko, R. Moore, K. Washburn and M. Negish. 1999. Phenobarbital responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene. Mol. Cell Bioi. 19, 6318-6322
|
27 |
Honkakoski, P., R. Moore, K. Washburn and M. Negishi. 1988. Activation by diverse xenochemicals of the 51-base pair phenobarbital-response enhancer module in the CYP2B10 gene. Mol. Pharmacal. 53, 597-601
|
28 |
Kim, J., G. Min and B. Kemper. 2001. Chromatin assembly enhances binding to the CYP2B1 phenobar-bital-responsive unit (PBRD) of nuclear factor-1, which binds simultaneously with constitutive andro-stane receptor (CAR)/retinoid receptor (RXR) and enhances CAR/RXR-mediated activation of the PBRU. J. Biol. Chem. 276, 7559-7567
DOI
ScienceOn
|
29 |
Forman, B. M., I. Tzameli, H. S. Choi, J. Chen, D. Simha, W. Seol, R. M. Evans and D. D. Moore. 1998. Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta. Nature. 395, 612-615
DOI
ScienceOn
|
30 |
Honkakoski, P., A. Kojo and M. A. Lang. 1992. Reg-ulation of the mouse liver cytochrome P450 2B subfamily by sex hormones and phenobarbital. Biochemical. J. 285, 979-983
|
31 |
Honkakoski, P. and M. Negishi. 1997. Character-ization of a phenobarbital-responsive enhancer mod-ule in mouse P450 Cyp2blO gene. J. BioI. Chem. 272, 14943-14949
DOI
ScienceOn
|
32 |
Honkakoski, P. and M. Negishi. 2000. Regulation of cytochrome P450 (CYP) genes by nuclear receptors. Biochem. J. 347, 321-337
DOI
ScienceOn
|
33 |
Choi, H-S., M. Chung, I. Tzameli, D. Simha, Y-K. Lee, W. Seol and D. Moore. 1997. Differential trans-activation by two isoforms of the orphan nuclear hormone receptor CAR. J. BioI. Chem. 272, 23565-23571
DOI
ScienceOn
|
34 |
Honkakoski, P., I. Zelko, T. Sueyoshi and M. Negishi. 1998. The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene. Mol. Cell Bioi. 18, 5652-5658
|
35 |
Bhagwat, S. V., B. C. Leelavathi, S. K. Shankar, M. R. Boyd and V. avindranath. 1995. Cytochrome P450 and associated monooxygenase activities in the rat and human spinal cord-induction, immunological char-acterization, and immunocytochemical localization. Neurosci. 68, 593-601
DOI
ScienceOn
|
36 |
Brodie, B. B., J. Axelrod, J. R. Cooper, L. Gaudette, B. N. LaDu, C. Mitoma and S. Udenfriend. 1955. Detox-ication of drugs and other foreign compounds by liver microsomes. Science 121, 603-604
DOI
|
37 |
Conney, A. H., C. Davison, R. Gasten and J. J. Burns. 1960. Adaptive increase in drug-metabolizing enzymes induced by phenobarbital and other drugs. J. Pharmacal. Exp. Therap. 130, 1-8
|
38 |
Baes, M., T. Gulick, H. S. Choi, M. G. Martinoli, D. Simha and D. D. Moore. 1994. A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response ele-ments. Mol. Cell Bioi. 14, 1544-1551
|
39 |
Cooper, D. Y., S. Levine, S. Narasimhulu, O. Ro-senthal and R. W. Estabrook. 1965. Photochemical action spectrum of the terminal oxidase of 'mixed function oxidase system. Science. 147, 400-402
DOI
ScienceOn
|
40 |
Axelrod, J. 1955. The enzymatic deamination of am-phetamine (benzedrine). J. Bioi. Chem. 214, 753-763
|