• Industrial Engineering and Management Systems
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• 제14권2호
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• pp.159-174
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• 2015

Remanufacturing used, end-of-life products is a complex problem involving multiple types of products that may share common parts. Recovery targets assigned by market demand and environmental legislation add more difficulty to the problem. Manufacturers now need to achieve specified take-back and recovery rates while fulfilling demands for remanufactured products. To assists in the demand- and legislation-driven remanufacturing of a family of products (i.e., multiple products that share common parts), this paper introduces a bi-objective mixed integer linear programming (MILP) model for optimizing remanufacturing. The model identifies optimal remanufacturing plans for a product family, whereby, the remanufacturer can achieve demand and recovery targets more profitably and in an environmentally-friendly manner. The model can also be used to quantify and justify the economic and environmental benefits of a product family from a remanufacturing perspective. A case study is presented for remanufacturing an alternatorfamily of products.

• International Journal of Concrete Structures and Materials
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• 제8권3호
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• pp.185-199
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• 2014

As the national transportation infrastructure ages and deteriorates, many existing bridges require frequent and costly maintenance and repairs. The objective of this work was to synthesize new and existing types of beam end coatings and treatments that have been proven to extend the life of new and existing concrete and steel bridge beams. A comprehensive literature review, along with online surveys and phone interviews of State department of transportations (DOTs) and coating manufacturers was conducted to gather information about existing and recently developed technologies. The study revealed that while many promising coatings and treatments are offered on the market, there is a lack of readily available laboratory results that would enable direct comparison of the available methods. This finding applies in terms of the coatings' durability and the potential for extending the service life of existing bridges. Most of the interviewed State DOTs' personnel assessed the products listed in respective DOT's Qualified Products Lists as performing 'well'. However, there was significant variability between states in the type of the products used. Among the agencies contacted, none was able to suggest the most promising or advanced products, either for concrete or steel bridge beam end treatments. This suggests that comprehensive laboratory evaluation would be necessary for selecting the best available beam end treatments and coatings.

• 대한산업공학회지
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• 제34권1호
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• pp.79-89
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• 2008

An end-of-life strategy is concerned with how to disassemble a product and what to do with each of the resultingdisassembled parts. A sound understanding of the end-of-life strategy at the early design stage could improve theease of disassembly and recycling in an efficient and effective manner. Therefore, the end-of-life decisionmaking for environmental conscious design has become a great concern to product manufacturers.We introduce a novel concept ofeco-architecture which represents a scheme by which the physical componentsare allocated to end-of-life modules. An end-of-life module is a physical chunk of connected components or afeasible subassembly which can be simultaneously processed by the same end-of-life option without furtherdisassembly. In this paper, a method for analyzing the eco-architecture of a product at the configuration designstage is proposed. It produces an optimal eco-architecture under the given environmental regulations. To dealwith the case ofa complex product, the method is extended for analyzing hierarchical eco-architecture.

• Industrial Engineering and Management Systems
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• 제2권1호
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• pp.35-44
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• 2003

Recovery of end-of-life (EOL) products is an environmentally and economically sound way to achieve many of the goals of sustainable development. Many product recovery systems are dependent upon destructive disassembly such as shredding, which undesirably causes a large volume of shredder dust and makes parts reuse impossible. Although non-destructive disassembly has been considered as an alternative for solving the problems, the classification of disassembled items has not been sufficiently investigated. In this paper, we propose a model that mathematically optimizes the disassembly and classification of EOL products. Based on the AND/OR graph that illustrates all possible disassembly sequences of a given product, we identify the physical properties that are considered as constraints in the model. As a result of the solution procedure, the recovery problem can be transformed into a mixed integer linear programming (MILP) model. We show an example that illustrates the concept of our model.

• 산업공학
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• 제20권2호
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• pp.154-161
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• 2007

When the electrical appliances such as TVs and refrigerators become obsolete, they must be collected to the recycling centers to avoid environmental damages. The obsolete home appliances are first moved to the regional collection point; and then transported to one of the recycling centers. Each recycling center has a limited capacity; and some recycling centers can process only certain types of products. For given locations of the existing collection points and recycling centers, optimally assigning the obsolete home appliances of each type from each collection point to the recycling centers can significantly reduce the total transportation cost. We formulate this problem as an LP problem. We also present an approach to determine the locations of additional recycling centers in order to alleviate the over-utilization of the current recycling centers.

• 생약학회지
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• 제39권3호
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• pp.223-227
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• 2008

Advanced glycation end products (AGEs) contribute to the progression of micro and macrovsacular complication of diabetes and therefore present a promising target for therapeutic agents. In this study, 40 Korean herbal medicines have been investigated with an in vitro evaluation system using AGEs inhibitory activity. Of these, 21 herbal medicines $(IC_{50}<50{\mu}g/ml)$ exhibited an inhibitory activity against AGEs formation compared with anminoguanidine $(IC_{50}=72.12{\mu}g/ml)$. Particularly, 7 herbal medicines, Actinidia arguta (root and stem), Crataegus pinnatifida (twig), Camellia japonica (whole), Kalopanax pictus (bark), Lagerstroemia indica (leaf-stem), Reynoutria sachalinensis (root) showed more potent inhibitory activity (approximately 3-10 fold) than the positive control aminoguanidine.

• 생약학회지
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• 제40권4호
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• pp.388-393
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• 2009

Advanced glycation end products (AGEs) have been implicated in the development of diabetic complications. The AGEs inhibitors or cross-link breakers attenuate various functional and structural manifestations of diabetic complications. In this study, 64 herbal medicines from China and Vietnam have been investigated with an in vitro evaluation system using AGEs inhibitory activity. Of these, eight herbal medicines ($IC_{50}$<50 ${\mu}g$/ml) were found to have strong AGEs inhibitory activity compared with aminoguanidine (14 days, $IC_{50}$=75.98 ${\mu}g$/ml; 28 days, $IC_{50}$=88.27 ${\mu}g$/ml). Particularly, four herbal medicines, Buddleja officinalis (whole plant), Syzygium cuminii (leaf), Eugenia caryophyllate (seed), and Paeonia suffruticosa (root) showed more potent inhibitory activity (approximately 5-6 fold) than the positive control aminoguanidine.

• 생약학회지
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• 제46권3호
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• pp.260-267
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• 2015

Advanced glycation end products (AGEs) have been postulated to play a central role in the development of diabetic complications. A variety of different agents that inhibit AGEs have been under investigation. In this study, 111 herbal medicines from China have been investigated with an in vitro evaluation system using AGEs formation inhibitory activity. Of these, 9 herbal medicines (IC₅₀: <5 μg/ml) were found to have significant AGEs formation inhibitory activity. Particularly, herbal medicines Barleria cristata (leaves), Calotropis gigantea (stems), Ardisia virens (leaves), Dalbergia yunnanensis (leaves) Pittosporum runcatum (leaves), Ardisia japonica (leaves), Rhododendron racemosum (twigs), Oxyria sinensiss (aerial parts), Pyrrosia calvata (whole plants), showed more potent inhibitory activity (approximately 15-40 fold) than the positive control aminoguanidine (IC₅₀: 76.47 μg/ml).

• 생약학회지
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• 제42권1호
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• pp.46-53
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• 2011

Advanced glycation end products (AGEs) have been postulated to play a central role in the development of diabetic complications. A variety of different agents that inhibit AGEs have been under investigation. In this study, 66 herbal medicines from China have been investigated with an in vitro evaluation system using AGEs formation inhibitory activity. Of these, 31 herbal medicines ($IC_{50}$ < $50\;{\mu}g/ml$) were found to have significant AGEs formation inhibitory activity. Particularly, 5 herbal medicines, Camptotheca acuminata (branches and leaves), Quercus franchetii (branches), Camellia pitardii (leaves, branches, and fruits), Antidesma bunius (whole plants), and Loranthus parasiticus (whole plants) showed more potent inhibitory activity (approximately 6-20 fold) than the positive control aminoguanidine ($IC_{50}=52.96\;{\mu}g/ml$).

• 생약학회지
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• 제46권3호
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• pp.268-278
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• 2015

In this study, 80 herbal medicines from Vietnam have been investigated with an in vitro evaluation system using advanced glycation end products (AGEs) formation inhibitory activity. Of these, 10 herbal medicines (IC₅₀: <5 μg/ml) were found to have significant AGEs formation inhibitory activity. Particularly, herbal medicines Strobilanthes pateriformis (aerial parts), Rhodamnia dumetorum (twigs), Glochidion rubrum (twigs), Dipterocarpus obtusifolius (twigs), Bombax ceiba (twigs), Amesiodendron chinense (twigs), Bauhinia coccinea (twigs), Lithocarpus laouanensis (twigs), Bauhinia bracteata (twigs) and Connarus paniculatus (twigs), showed more potent inhibitory activity (approximately 16-31 fold) than the positive control aminoguanidine (IC₅₀: 76.47 μg/ml).