• Title/Summary/Keyword: encounter complex

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NMR Studies on Transient Protein Complexes: Perspectives

  • Suh, Jeong-Yong;Yu, Tae-Kyung;Yun, Young-Joo;Lee, Ko On
    • Journal of the Korean Magnetic Resonance Society
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    • v.18 no.1
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    • pp.1-4
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    • 2014
  • It is generally understood that protein-protein interactions proceed via transient encounter complexes that rapidly evolve into the functional stereospecific complex. Direct detection and characterization of the encounter complexes, however, been difficult due to their low population and short lifetimes. Recent application of NMR paramagnetic relaxation enhancement first visualized the structures of the encounter complex ensemble, and allowed the characterization of their physicochemical properties. Further, rational protein mutations that perturbed the encounter complex formation provided a clue to the target search pathway during protein-protein association. Understanding the structure and dynamics of encounter complexes will provide useful information on the mechanism of protein association.

Double zeros of the szego kernel

  • Lee, Moo-Hyun
    • Journal of the Korean Mathematical Society
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    • v.31 no.3
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    • pp.457-466
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    • 1994
  • When we study complex analysis, we often encounter multi-valued functions. Provably the best known example would be $\sqrt{z}$, which has a singularity at the oritgin. In general, let $\Omega_1 and \Omega_2$ be domains in C, and let $\Gamma$ be a subvariety of $\Omega_1 \times \Omega_2$.

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Expert System Application in Agriculture (전문가 시스팀의 농업에의 적용)

  • Kim, Y.J.
    • Journal of Biosystems Engineering
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    • v.16 no.3
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    • pp.327-335
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    • 1991
  • In Korea, farming population is rapidly decreased in each decade. Consequently, farming is becoming more complex with multi cropping, animal production and green house farming. In order to encounter this complexity of farming, expert system applications on diagnosis, planning, designing, management, control, and training are demanded to meet the needs of agricultural society. In this article, expert system establishment procedures are stated step by step and extensive literature review was conducted on the expert system development techniques.

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Effects of Movement When Using Visual Media to Determine Encounter Standards1a (휴양지역의 조우 평가기준 설정을 위한 시각매체의 활용시 움직임의 효과)

  • Kim, Sang-Oh;Shelby, Bo
    • Korean Journal of Environment and Ecology
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    • v.23 no.4
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    • pp.309-316
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    • 2009
  • The usefulness of media representations for assessing normative standards depends in part on how accurately media reflect "on-the-ground" resource conditions. This study compared encounter standards based on still and moving pictures to assess movement effects. The study location was the Jungmoeri area of Mudeungsan Provincial Park (MPP) in Korea. A total of 50 college students participated in a laboratory experiment where they evaluated still and moving pictures constructed using Photoshop and Flash computer programs. For the maximum acceptable number (MAN), however, there was no significant difference of ratings between still and moving pictures, and the overall encounter norm curves were nearly identical. There were some "method findings" for ordering effects and percent of people moving, but for a resource manager developing standards there was no advantage to the more complex logistics of using moving pictures to assess this particular impact. The trade-offs of using more sophisticated media are discussed, and more research is needed to further explore factors such as movement of sound in evaluation of other resource conditions.

StrokeMed: an integrated literature database for stroke and the differentiation of stroke syndrome

  • Kim, Young-Uk;Kim, Jin-Ho;Park, Young-Kyu;Kim, Young-Joo
    • Interdisciplinary Bio Central
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    • v.2 no.2
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    • pp.2.1-2.4
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    • 2010
  • Complex diseases, such as stroke and cancer, have two or more genetic influences and are affected by environmental factors, which complicate them. Due to the complex characteristics of these diseases, we must search and study comprehensive literature-based article resources. Some disease-related literature databases have been developed through specialized journal issues or major websites. Most of them, however, are scattered throughout a website, and users encounter difficulties in finding accurate and comprehensive information easily and quickly. We developed StrokeMed, an integrated literature database for stroke and the differentiation of stroke syndrome. The system allows users to explore PubMed search results, categorized by MeSH (Medical Subject Headings), and the differentiation of stroke syndrome in Oriental medicine. StrokeMed collects data from important sites, such as PubMed, Scirus, and Scopus, automatically to maintain higher-quality and updated content. Currently, the system indexes more than 20,000 PubMed abstracts that are related to stroke, stroke etiology, and Oriental medicine. The system provides valuable literature information to the scientific and medical fields in stroke.

Evolution of cometary dust particles to the inner solar system: Initial conditions, mutual collision and final sinks

  • Yang, Hongu;Ishiguro, Masateru
    • The Bulletin of The Korean Astronomical Society
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    • v.42 no.2
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    • pp.48.3-49
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    • 2017
  • Interplanetary space of the solar system contains a large number of dust particles, referred to as Interplanetary Dust Particles (IDPs) cloud complex. They are observable through meteors and zodiacal lights. The relative contribution of possible sources to the IDPs cloud complex was an controversial topic, however, recent research (Yang & Ishiguro, 2015 and references therein) suggested a dominance of cometary origin. In this study, we numerically investigated the orbital evolution of cometary dust particles, with special concerns on different evolutionary tracks and its consequences according to initial orbits, size and particle shape. The effect of dust particle density and initial size-frequency distribution (SFD) were not decisive in total cloud complex mass and mass supply rate, when these physical quantities are confined by observed zodiacal light brightness and dust particle SFD at 1 au. We noticed that, if we assume the existence of fluffy aggregates discovered in the Earth's stratosphere and the coma of 67P/Churyumov-Gerasimenko, the required mass supply rate decreases significantly. We also found out that close encounters with planets (mostly Jupiter) are the dominating factor of the orbital evolution of dust particles, as the result, the lifetime of cometary dust particles are shorter than Poynting-Robertson lifetime (around 250 thousand years). As another consequence of severe close encounters, only a small fraction of cometary dust particles can be transferred into the orbit < 1 au. This effect is significant for large size particles of ${\beta}$ < 0.01. The exceptional cases are dust particles ejected from 2P/Encke and active asteroids. Because they rarely encounter with Jupiter, most dust particles ejected from those objects are governed by Poynting-Robertson effect and well transferred into the orbits of small semimajor axis. In consideration of the above effects, we directly estimated probability of mutual collisions between dust particles and concluded that mutual collisions in the IDPs cloud complex is mostly ignorable, except for the case of large sized particles from active asteroids.

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Stress Analysis of Composite Plate with an Elliptical Hole or a Crack Using Complex Potentials (복소퍼텐셜을 이용한 타원공 또는 균열을 가진 복합재 평판 응력해석)

  • Kwon, Jung-Ho;Hwang, Kyung-Jung
    • Composites Research
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    • v.20 no.5
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    • pp.56-63
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    • 2007
  • An approach using complex potentials is presented for analysis of composite plate with an elliptical hole or a rectilinear crack. Composite structure is susceptible to encounter impact damages, which lead to considerable decrease in its residual strength. Such impact damages could be modeled as an equivalent elliptical hole or notch-like crack. Even though finite element method is widely used to analyze stresses or fracture mechanics parameters around such damage, it is tedious to make successive FE-modeling for damage tolerance assessment under fatigue loadings. In this point of view, the solutions based on complex potentials are very simple and easy to use. The computed results are also compared and discussed with those from FEA.

A Study on the Method to Define System Requirements for Urban Maglev Train (도시형 자기부상열차 시스템 요구사항 정의 방안 연구)

  • Chung, Kyung-Yul;Park, Chul-Ho;Choi, Chun-Ho;Song, Sun-Ho
    • Proceedings of the KIEE Conference
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    • 2007.10c
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    • pp.10-13
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    • 2007
  • System requirements (SRs), which describe the technical attributes to be satisfied by a desired system, serve as a fundamental guideline for system development. Standard methods and processes to define SRs are suggested in systems engineering literature. But in practice, we encounter many difficulties in defining and managing SRs since there are few experiences on development of complex systems in accordance with systems engineering processes of development. In this paper, to expanding SRs management experiences in a working-level, we reviewed problems occured in SRs defining process in 'Urban MAGLEV Train Project', and analyzed our activities to adjust and solve the problems.

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Construction and roles of computer simulator for digital controller design

  • Nakamura, Masatoshi
    • 제어로봇시스템학회:학술대회논문집
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    • 1988.10b
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    • pp.909-914
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    • 1988
  • The structure of a digital controller based on modern control theory is more complex than that of a PID controller. In implementing the digital control of an actual system by using the digital controller, we often encounter gaps between theory and practice e.g. quantization error, sampling error, modeling error, contaminated noise etc. In such cases, simulator plays an important role in detecting difficulties. This paper demonstrates the importance of the computer simulator for designing a digital controller. The controller and the simulator are constructed by different computer respectively, with a link between the blocks by analogue signals through the A/D, D/A converters. Through the simulator test, we can evaluate the digital controller; identify and solve difficulties in the digital control. The controller, which pasted the simulator test, is used identically in the actual system. This was a successful procedure for designing the controller. As an example, we successfully constructed the digital controller using the computer simulator for inverted pendulum control. We then compared the control results of simulator and actual equipment. Furthermore we commented on the construction of the computer simulator which exactly expressed the actual system.

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Triangular units based method for simultaneous optimizations of planar trusses

  • Mortazavi, Ali;Togan, Vedat
    • Advances in Computational Design
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    • v.2 no.3
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    • pp.195-210
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    • 2017
  • Simultaneous optimization of trusses which concurrently takes into account design variables related to the size, shape and topology of the structure is recognized as highly complex optimization problems. In this class of optimization problems, it is possible to encounter several unstable mechanisms throughout the solution process. However, to obtain a feasible solution, these unstable mechanisms somehow should be rejected from the set of candidate solutions. This study proposes triangular unit based method (TUBM) instead of ground structure method, which is conventionally used in the topology optimization, to decrease the complexity of search space of simultaneous optimization of the planar truss structures. TUBM considers stability of the triangular units for 2 dimensional truss systems. In addition, integrated particle swarm optimizer (iPSO) strengthened with robust technique so called improved fly-back mechanism is employed as the optimizer tool to obtain the solution for these class of problems. The results obtained in this study show the applicability and efficiency of the TUBM combined with iPSO for the simultaneous optimization of planar truss structures.