• Ocean and Polar Research
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• v.42 no.1
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• pp.33-47
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• 2020

The bulk and partition geochemistry was studied in two sediment cores collected from the axial valley of the north-central Fonualei Rift and Spreading Center (FRSC), Lau back-arc Basin, southwest Pacific. The sediments consist of mostly volcanic ash, although minor amounts of biogenic and other components were present in some intervals. The major element composition of bulk sediments recalculated to a carbonate-free basis was in good agreement with the magma compositions of the adjacent Tofua Arc and the FRSC, with only significant difference in Mn content. The enrichment of Mn and other associated elements (e.g. Cu, Co, Ni, and P) is attributed to hydrothermal input to the sediments, as evidenced by their significant partitioning in the non-detrital phases according to the partition geochemistry. Hydrogenetic and diagenetic inputs were assessed to be relatively insignificant. Estimated hydrothermal Mn fluxes during the Holocene ranged between 5.0 and 37.1 mg cm^-2 kyr^-1, with the higher values in younger sediments, suggesting enhanced hydrothermal activity. The hydrothermal Mn fluxes comparable to or higher than those reported from other spreading centers with strong hydrothermal activities may indicate the presence of unknown hydrothermal vent sites and/or topographic restriction on the dispersal of hydrothermal plumes in the northern part of the FRSC.

• Journal of Acupuncture Research
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• v.22 no.4
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• pp.131-141
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• 2005

Objectives : Saam acupuncture has evident principles of prescription based on acupuncture tonification and purgation of Nan-gyeong but many prescriptions of Saam acupuncture are not typical patterns. This paper studies principles of prescriptions of the king fire and the premier fire. Methods : Through investigation of many medical documents concerning king fire and the premier fire, the author explained of physiological and pathological principle of king and the premier fire, also explained of interacting mechanism through five element. And The theoretical authorities of analysis are Nan-gyeong, works of Joo dan-gye and Li dong-won. Results & Conclusion : 1. The sufficiency and the control of the water is the key to treat the disease by fire. Considering the attack and the treatment of disease, heart and liver give rise to fire in its early stage and kidney and lung are the key to treatment. 2. Consequently the pathology of the disease from fire is corresponding to the theory- Yang Sufficient, Yin Deficient- of Joo dan-gye. It seems that the theory of Joo dan-gye influenced on the medical theory of Saam Acupuncture. 3. On that account I believe that the study of medical theories of the Geum and Won Dynasty that various medical theories had appeared is very available for Saam Acupuncture. At present global warming is accelerating because environmental pollution has been increasing. Therefore the damage of fire to human body will be more and more severe and extensive. Because in the future medical plants will not be free from environmental pollution, acupuncture will be very confidential treatment.

• Journal of Environmental Health Sciences
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• v.30 no.3
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• pp.230-238
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• 2004

The adverse health effects of a number of environment pollutions are related to the formation of free radicals. Induction of antioxidant defensive system in the response to an oxidative attack is an essential element of the cell to survive. CYP2E1 is easily induced by organic solvents and induces continuous formation of reactive oxygen species (ROS). ${\gamma}$-Glutamyltranspeptidase (${\gamma}$GT) plays an important role in glutathione metabolism and xenobiotic detoxification. To evaluate the characteristic of oxidative stress which induces GGT expression and to understand human antioxidant defensive response against oxidative stress induced by CYP2E1, we studied regulation of ${\gamma}$GT enzyme expression in response to various oxidative stresses in human HepG2 cells. The ${\gamma}$GT activity was not modified after exposure of acute oxidative stress inducing agents (ferric nitrilotriacetate, cumene hydroperoxide, ADP-Fe, O-tetradecanoylphorbol-13-acetate, tumor necrosis factor-alpha). To induce continuous exposure of cells to ROS, HepG2 cells were transfected by human CYP2E1 gene transiently. The CYP2E1 activity was verified with chlorzoxazone hydroxylation. Transfection of CYP2E1 showed continuous 60% increase in intracellular ROS and 240 % increase in microsomal ROS. CYP2E1 overexpressing cells showed increased ${\gamma}$GT activity (2.5-fold). The observed enhancement of ${\gamma}$GT activity correlated with a significant increase of ${\gamma}$GT mRNA (2.1-fold). Treatment with antioxidant strongly prevented the increase in ${\gamma}$GT activity. The CYP2E1 overexpression did not modify toxicity index and increased glutathione levels. These results show that continuous exposure of cells to ROS produced by CYP2E1 up-regulates ${\gamma}$GT; This may be one of the adaptive antioxidant responses of cells to oxidative insult. Present study also suggests that the induction of ${\gamma}$GT could be used as a marker of oxidative stress induced by exposure to organic solvents.

• Journal of the Korean Institute of Rural Architecture
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• v.12 no.4
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• pp.77-86
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• 2010

This study is about Tak Mok theory of feng-shui ideology which was main thought in Choson dynasty or some other thoughts and noble families' thought of garden building : planting trees and properties of the noble families garden. The result from the study of noble family's garden molding is as follows. In the noble family's garden molding, there were considerations of plant ecology known through long experience and the functional aspect of planting tree and esthetic sense of housing circumstances, in addition to feng-shui thought, Taoist thought and the doctrine of the five natural elements of the positive vs. negative. We can learn Choson's noble family's garden included playroom as well as symbolic and incantatory meaning. Also in the thought of noble family's garden molding we can found proper element for modern housing plan such as an ecological peculiarity or functional aspect of dwelling circumstance. And we can also found they didn't show a rejection symptoms against nature but enclosed with straight form which was traditional trait, and each space of it is composed organically. Also we knew they selected a diverse and refined technique with it's decorating the Choson dynasty playful and meditative space. We found that the key point of the thought of noble family's garden molding were on the basis of Confucianal mood, content amid poverty thought and free technique of it.

• Smart Structures and Systems
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• v.15 no.3
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• pp.683-698
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• 2015

Railroad bridges form an integral part of railway infrastructure throughout the world. To accommodate increased axel loads, train speeds, and greater volumes of freight traffic, in the presence of changing structural conditions, the load carrying capacity and serviceability of existing bridges must be assessed. One way is through system identification of in-service railroad bridges. To dates, numerous researchers have reported system identification studies with a large portion of their applications being highway bridges. Moreover, most of those models are calibrated at global level, while only a few studies applications have used globally and locally calibrated model. To reach the global and local calibration, both ambient vibration tests and controlled tests need to be performed. Thus, an approach for system identification of a railroad bridge that can be used to assess the bridge in global and local sense is needed. This study presents system identification of a railroad bridge using free vibration data. Wireless smart sensors are employed and provided a portable way to collect data that is then used to determine bridge frequencies and mode shapes. Subsequently, a calibrated finite element model of the bridge provides global and local information of the bridge. The ability of the model to simulate local responses is validated by comparing predicted and measured strain in one of the diagonal members of the truss. This research demonstrates the potential of using measured field data to perform model calibration in a simple and practical manner that will lead to better understanding the state of railroad bridges.

• Structural Engineering and Mechanics
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• v.32 no.2
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• pp.283-300
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• 2009

The characteristic response of a structure to blast load may be divided into two distinctive phases, namely the direct blast response during which the shock wave effect and localized damage take place, and the post-blast phase whereby progressive collapse may occur. A reliable post-blast analysis depends on a sound understanding of the direct blast effect. Because of the complex loading environment and the stress wave effects, the analysis on the direct effect often necessitates a high fidelity numerical model with coupled fluid (air) and solid subdomains. In such a modelling framework, an appropriate representation of the blast load and the high nonlinearity of the material response is a key to a reliable outcome. This paper presents a series of calibration study on these two important modelling considerations in a coupled Eulerian-Lagrangian framework using a hydrocode. The calibration of the simulated blast load is carried out for both free air and internal explosions. The simulation of the extreme dynamic response of concrete components is achieved using an advanced concrete damage model in conjunction with an element erosion scheme. Validation simulations are conducted for two representative scenarios; one involves a concrete slab under internal blast, and the other with a RC column under air blast, with a particular focus on the simulation sensitivity to the mesh size and the erosion criterion.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.34 no.11
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• pp.1733-1740
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• 2010

The analysis of the dynamic behavior of the packaging of a drum washing machine has been carried out under the drop impact conditions. LS-DYNA software is used for performing the finite element analysis, and the validations are performed by comparing with the impact acceleration, effective stress and deformation of cushioned package with high-speed camera during free drop test. By analyzing the cushion characteristics and the design parameters of the original packaging, a packaging with an improved design is developed, and this design is validated on the basis of the results of the distribution test which consists of drop test, vibration test, stacking test, squeez test and so on. The drop impact simulation and analysis methods developed in this study can be adopted to successfully improve the cushioning provided by the packaging and to reduce the cost involved in developing new packaging for drum washing machines.

• Bulletin of the Korean Chemical Society
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• v.33 no.6
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• pp.1839-1844
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• 2012

We have investigated binding between wild-type and mutant Heat Shock Factor (HSF) DNA binding domains (DBDs) with 17-bp HSE containing a central 5'-NGAAN-3' element by equilibrium analytical ultracentrifugation using multi-wavelength technique. Our results indicate that R102 plays critical role in HSE recognition and the interactions are characterized by substantial negative changes of enthalpy (${\Delta}H^0_{\theta}=-9.90{\pm}1.13kcal\;mol^{-1}$) and entropy (${\Delta}S^0_{\theta}=-12.46{\pm}3.77cal\;mol^{-1}K^{-1}$) with free energy change, ${\Delta}G^0_{\theta}$ of $-6.15{\pm}0.03kcal\;mol^{-1}$. N105 plays minor role in the HSE interactions with ${\Delta}H^0_{\theta}$ of $-2.54{\pm}1.65kcal\;mol^{-1}$, ${\Delta}S^0_{\theta}$ of $19.28{\pm}5.50cal\;mol^{-1}K^{-1}$ and ${\Delta}G^0_{\theta}$ of $-8.35{\pm}0.05kcal\;mol^{-1}$, which are similar to those observed for wild-type DBD:HSE interactions (${\Delta}H^0_{\theta}=-3.31{\pm}1.86kcal\;mol^{-1}$, ${\Delta}S^0_{\theta}=17.38{\pm}6.20cal\;mol^{-1}K^{-1}$ and ${\Delta}G^0_{\theta}=-8.55{\pm}0.06kcal\;mol^{-1}$) indicating higher entropy contribution for both wild-type and N105A DBD bindings to the HSE.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.22 no.6
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• pp.627-637
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• 2009

Composite materials have been employed in the various engineering applications due to high mechanical performances including high strength-weight ratio and high degree of free formability. Due to complex manufacturing process, however, it can have intrinsic randomness in the material constants which affect the deterministic behavior of the composite structures. In this study, we suggest a formulation for stochastic finite element analysis considering the spatial randomness of Poisson's ratio. Considering the reciprocal relation between elastic moduli and Poisson's ratios in the two mutually orthogonal axes, one of two values of Poisson's ratio can be expressed in terms of the other. Using this, the relation between stress resultants and strains is derived in the ascending order of power of the stochastic field function, which can be directly used in the formulation to obtain the coefficient of variation of responses. The adequacy of the proposed scheme is demonstrated by comparison with the results of Monte Carlo analysis.

• Structural Engineering and Mechanics
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• v.40 no.5
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• pp.637-654
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• 2011

The present paper studies the variation of the natural frequencies and mode shapes of rectangular plates carrying a three degree-of-freedom spring-mass system (subsystem), when the subsystem changes (stiffness, mass, moment of inertia, location). An analytical approach based on Lagrange multipliers as well as a finite element formulation are employed and compared. Numerically reliable results are presented for the first time, illustrating the convenience of using the present analytical method which requires only the solution of a linear eigenvalue problem. Results obtained through the variation of the mass, stiffness and moment of inertia of the 3-DOF system can be understood under the effective mass concept or Rayleigh's statement. The analysis of frequency values of the whole system, when the 3-DOF system approaches or moves away from the center, shows that the variations depend on each particular mode of vibration. When the 3-DOF system is placed in the center of the plate, "new" modes are found to be a combination of the subsystem's modes (two rotations, traslation) and the bare plate's modes that possess the same symmetry. This situation no longer exists as the 3-DOF system moves away from the center of the plate, since different bare plate's modes enable distinct motions of the 3-DOF system contributing differently to the "new' modes as its location is modified. Also the natural frequencies of the compound system are nearly uncoupled have been calculated by means of a first order eigenvalue perturbation analysis.