• Title/Summary/Keyword: efficacy rate

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Quantitative Evaluation on Laser Performance for Endovenous Photocoagulation (레이저를 이용한 하지정맥류 치료의 정량화 연구)

  • Ahn, Minwoo;Nguyen, Van Phuc;Oh, Junghwan;Kang, Hyun Wook
    • Journal of Biomedical Engineering Research
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    • v.35 no.3
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    • pp.62-67
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    • 2014
  • The purpose of the study was to identify the effect of laser parameters on photocoagulation to maximize safety and efficacy during varicose vein treatment. CW and pulsed modes at 1470 nm were initially compared as a function of power on bovine liver tissue. In the pulsed mode, various parameters including repetition rate, duty cycle, and irradiation time were compared to evaluate tissue response during thermal treatment. The results demonstrated that CW and pulsed modes yielded almost similar coagulation development possibly due to shorter irradiation time of 5 sec. Regardless of laser mode, both repetition rate and duty cycle presented constant coagulation rate whereas longer irradiation time facilitated coagulation process.

The effect of entrepreneurial motivation on the entrepreneurial performance focusing on potential entrepreneurs and entrepreneurs: Mediating role of entrepreneurship (창업동기요인이 예비창업자와 기창업자의 창업성과에 미치는 영향 : 기업가정신의 매개효과를 중심으로)

  • Lee, Byeong-Gweon;Jeon, In-Oh
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.9 no.6
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    • pp.213-230
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    • 2014
  • Increasing unemployment rate and creation of new jobs are most important issues around the world recently. Then many developed countries, including Republic of Korea, establish and enforce a variety of start-up activation policies to increase employment rate and boom up the national economy. Establishing linkage of entrepreneurship motivation, entrepreneurship, entrepreneurial intention and firm performance, focusing on potential entrepreneurs and entrepreneur, it could provide personalized and targeted entrepreneurial policy programs to increase entrepreneurship, because entrepreneurship is the most important factor to activate startups. On this study, it established factors of entrepreneurial motivation on potential entrepreneurs and entrepreneurs, and analyzed the linkage of factors of entrepreneurial motivation, entrepreneurship, entrepreneurial intention(potential entrepreneurs) and firm performance(entrepreneurs). For analysis, this study conducted descriptive statistics, reliability analysis, factor analysis to verify validity, correlation analysis, and regression to analyze influence between factors. Potential entrepreneurs group has 202 samples, and findings show self-efficacy, social network, economic status and government policy influence on entrepreneurship positively. And self-efficacy, startup education, economic status and government policy have a positive effect on entrepreneurial intention, too. Entrepreneurs group has 212 samples, and findings show self-efficacy, social network and economic status influence on entrepreneurship. And each linkage has a positive effect, that self-efficacy - financial and non-financial performance, startup education - financial and technological performance, social network - financial performance, economic status - financial and non-financial performance, and government policy - financial and technological performance.

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Efficacy and Survival-associated Factors with Gefitinib Combined with Cisplatin and Gemcitabine for Advanced Non-small Cell Lung Cancer

  • Fang, Hong;Lin, Rong-Yan;Sun, Ming-Xia;Wang, Qian;Zhao, Yu-Liang;Yu, Jing-Lin;Tian, Yan;Wang, Xiao-Yun
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.24
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    • pp.10967-10970
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    • 2015
  • Objective: To analyze the efficacy and survival associated factors of gefitinib combined with cisplatin and gemcitabine for advanced non-small cell lung cancer. Materials and Methods: A total of 57 patients with advanced non-small cell lung cancer (NSCLC), who received platinum-based chemotherapy regimens for more than 1 cycle, were treated with gefitinib combined with cisplatin and gemcitabine until disease progression. Efficacy, survival time and adverse reactions were observed. The Kaplan-Meier method was adopted for analysis of survival and Cox regression for associated influencing factors. Results: The patients were followed up until October 31, 2013, and the median follow-up time was 19 months. Of 57 patients, there were 4 (7.0%) with complete remission (CR), 8 (14.0%) with partial remission, 31 (54.4%) with stable disease, and 14 (24.6%) with disease progression. The remission rate was 21.1% and the disease control rate was 75.4%. The median progression-free survival (PFS) time and the median overall survival time were 10 months and 15.2 months. The one-year, two-year and three-year survival rates were 47.4%, 23.3% and 10.0%. Gender and pathological types were the independent risk factors influencing PFS time (P=0.028, P=0.009). Tumor pathological type and early efficacy were independent factors for the prognosis (P=0.018, P=0.000). Adverse reactions were mostly rashes of I~II degree and diarrhea and slightly increasing level of aminopherase. The skin adverse event incidence of III degree or above was 1.8% (1/57) and brain metastasis was foudn in 31.6% (18/57). Conclusions: Gefitinib combined with cisplatin andgemcitabine, is effective for patients with IIIb~IV NSCLC who received multiple cycles of chemotherapy.

Interpretation of Weeding Efficacy by Mixture Use of Herbicide Combination, Oxyfluorfen and Glyphosate (Oxyfluorfen과 Glyphosate 조합처리(組合處理) 모형(模型)의 혼용효과(混用效果)에 대한 해석적연구(解釋的硏究))

  • Guh, J.O.;Cho, Y.W.;Lee, K.H.
    • Korean Journal of Weed Science
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    • v.7 no.2
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    • pp.236-242
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    • 1987
  • The study was conducted to interprete the fluctuation of weed vegetation in plant-sociological impacts as affected by the mixture use of oxyfluorfen and glyphosate with various dosages. Also, intended to know the real interaction between two herbicides in weeding efficacies. The better efficacy from the above mixture was recognized than from the oxyfluorfen + paraquat mixture on the perennial-sites. In lower rate mixture of oxyfluorfen, the dominance index was increased by the annual grass species (ie. Digitaria), and of glyphosate by the biennial Stellaria and perennial species (ie. Artemisia). Also, the positive maximum action of both oxyfluorfen and glyphosate in various mixture rates was categorized upto 0.55kg ai/ha for oxyfluorfen and 0.35kg ai/ha for glyphosate, respectively. However, the interaction between the above two herbicides recognized actually as negative. Consequently, the use of mixture compound of oxyfluorfen with glyphosate are expected rather to promote the control efficacy of specific weed species, to enlarge the weeding spectrum and to prolong the weeding periods than to reduce the application rate of both chemicals depending on any synergic interactions.

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The Effect of Case-Based SBAR Communication Training Program on Critical Thinking Disposition, Communication Self-Efficacy and Communication Competence of Nursing Students (사례기반 SBAR 의사소통 교육프로그램이 간호대학생의 비판적 사고성향, 의사소통 자기효능감, 의사소통능력에 미치는 효과)

  • Park, Su-Jin;Choi, Hyo-Sin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.11
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    • pp.426-434
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    • 2018
  • The purpose of this study was to analyze the effects of case-based SBAR communication training program on critical thinking ability, communication self-efficacy and communication competence of nursing students. 112 sophomore students majoring in nursing were recruited from one university located in D city, and the data collection commenced on 18 December 2017 and was completed on 4 January 2018. The case-based SBAR communication training program consisted of pre-education, a pre-survey, a three-section program, and a post-survey. A one-group pretest-posttest design was used to collect the data, and frequency and paired t-test were analyzed by SPSS 21.0 program. The rate of satisfaction for interpersonal relationship was 75.0% and satisfaction rate for improvement on their major was 54.5%. Compared with before the program, critical thinking ability and communication competence were significantly improved after completion of the case-based SBAR communication training program (t=-4.237, p<.001; t=-2.734, p=.007). Communication self-efficacy was also improved after the case-based SBAR communication training program, but the difference was not significant. In conclusion, the case-based SBAR communication training program improved critical thinking ability and communication competence.

Selection of Aerial Spraying Control Agent and Susceptibility of Pinewood Nematode Vectors to Spraying Using Unmanned Aerial Vehicles (소나무재선충 매개충에 대한 항공방제 약제 탐색 및 무인항공기 살포에 의한 매개충의 약제 감수성)

  • Junheon Kim;Sangjune Nam;Jinyoung Song
    • Korean journal of applied entomology
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    • v.62 no.1
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    • pp.43-48
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    • 2023
  • The efficacy of spinetoram sprayed from an unmanned helicopter to control two insect vectors of pine wood nematodes, Monochamus alternatus and M. saltuarius was assessed. By using a ULV (Ultra Low Volume) sprayer, the mortality rates of phenthoate, bifenthrin, etofenprox, and diflubenzuron, which are registered for use against coleopteran insects, indoxacarb and spinetoram, which are registered for use against lepidopteran insects, were evaluated for efficacy as aerial spraying agents. The ULV test, using 33- and 55-fold dilutions of phenthoate, bifenthrin, indoxacarb, and spinetoram demonstrated a 100% insect mortality rate upon contact and feeding mortality on the third day after treatment, while etofenprox and diflubenzuron exhibited a slightly lower mortality rate than the remaining compounds. Consequently, spinetoram was selected as a candidate pesticide for aerial spraying and its efficacy to control the insect vectors was assessed. The x 33 dilution of spinetoram resulted in a 98.6-100% control efficacy against two insect vectors. However, risk assessment for bees following aerial spraying will be necessary before applying the pesticide to control insect vectors.

The Efficacy of Low-dose Aspirin Therapy for Controlled Ovarian Hyperstimulation in IVF-ET (체외수정시술 환자의 과배란유도시 저용량 아스피린 투여의 효용성에 관한 연구)

  • Lee, Eun-Sil;Lee, Sang-Hoon
    • Clinical and Experimental Reproductive Medicine
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    • v.28 no.3
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    • pp.225-233
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    • 2001
  • Objective : To evaluate the efficacy of low-dose aspirin on IVF outcome and endometrium in patients undergoing IVF-ET. Materials and Methods : From February, 2001 to Jun, 2001, 60 infertile patients were randomly divided into study group (28 cycles) and control group (32 cycles). The study group received a daily oral dose of 25 mg of aspirin for at least 2 weeks from first visiting day. Controlled ovarian hyperstimulation was initiated in all patients with the GnRH agonist starting in the midluteal phase of the previous cycle. Results: There were no significant differences in age of the patients, basal serum E2, LH, FSH level and endometrial thickness among two groups. There were no statistically significant differences between the study group and the control group respectively in dosage ($26.5{\pm}4.8$ vs $26.2{\pm}5.3$ amples) and duration ($10.4{\pm}4.2$ vs $9.8{\pm}5.3$ days) of gonadotropin administration, serum E2 level on the hCG administration day ($1823{\pm}342$ vs $1854{\pm}543$), LH ($14.5{\pm}2.7$ vs $14.8{\pm}3.1$), FSH ($16.7{\pm}3.4$ vs $18.3{\pm}4.7$), the number of follicles > 15 mm ($13.2{\pm}6.3$ vs $12.8{\pm}5.9$), the number of oocytes retrieved ($9.2{\pm}2.4$ vs $8.4{\pm}1.7$), the number of embryos transferred ($4.7{\pm}2.0$ vs $4.7{\pm}2.0$), fertilization rate (68.4% vs 64.5%), implantation rate (21.3% vs 17.6%), and clinical pregnancy rate (28.4% vs 26.2%). The endometrial thickness and the percentage of endometrial trilaminar pattern on hCG day were significantly higher in study group than control group ($12.9{\pm}3.7mm$ vs $10.4{\pm}2.8mm$, 78.3% vs 64.5%). Conclusion: Many reports suggest that low-dose aspirin improve ovarian response, implantation rate, fertilization rate, implantation rate, and pregnancy rate by increasing the blood flow, but we couldn't prove the significant effect of low-dose aspirin on the IVF outcome except on endometrium. This may be affected by dose of aspirin, duration, and number of patients studied. This trial is small, so our results highlight the need for a large randomized controlled trial to identify the effect of low-dose as pirin on IVF-ET outcome.

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Moderating Effect of Self-efficacy between Convergence-type Job Insecurity and Organizational Citizen Behavior (융복합형 직무불안정성과 조직시민행동간 자기효능감의 조절효과)

  • Han, Jin-Hwan
    • Journal of Digital Convergence
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    • v.14 no.5
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    • pp.237-245
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    • 2016
  • Anxiety for employment of workers has been increased due to rapid change of management environment, which tends to increase psychological instability on the job of all workers. Accordingly, this study examined the moderating effect of self-efficacy between job instability and organizational citizenship behavior. The research subjects were employees of small and medium companies in the manufacturing industry in Daejeon-si, Sejong-si and Chungcheongnam-do and Chungcheongbuk-do. 500 sheets of the questionnaire were distributed from August 5, 2015 to August 30, 2015. Among them, 321 were collected with 64.2% of the response rate. Total 312 sheets were used for analysis excluding 9 sheets with incomplete answers. The results are as follows. Firstly, it proved that job instability had negative (-) effect on organizational citizenship behavior. Secondly, in the relation between job instability and organizational citizenship behavior, there was moderating effect of self-efficacy. Accordingly, if self-efficacy of the workers is higher in the threat of job instability, it means organizational citizenship behavior would increase. In conclusion, in the current situation where there is instable survival of corporation and job, the management of small and medium manufacturing company needs to increase self-efficacy through training and internal reward to employees. The limit of the study is that the research subjects were employees of small and medium companies in the manufacturing industry in Daejeon-si, Sejong-si and Chungcheongnam-do and Chungcheongbuk-do. Accordingly, as situational peculiarity may be observed, it is required to have expanded study to more various areas, works and industries.

Characteristics of Small Business Start-Up and Effect of Preparation of Small Business Start-up on Business Performance -Focusing on Mediating Effect of Self-Efficacy (소상공인 창업자특성과 창업준비과정이 창업성과에 미치는 영향에 관한 연구 : 자기효능감 매개효과를 중심으로)

  • Kang, Young-Uk;Ha, Kyu-Soo
    • Journal of Digital Convergence
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    • v.10 no.9
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    • pp.239-251
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    • 2012
  • This study aims to seek the policies and the plans for the successful small business start-up through an exploratory study about the factors affecting the success rate of small business start-up. To measure the performance of the start-up business(sales revenue, net profit, and outcome expectancy), the characteristics of founders (experience, psychological characteristics) and the preparation of small business start-up were measured as independent variables and the self-efficacy was measured as a parameter. 427 small business owners were targeted and structured self-administered questionnaires were collected from them. For the data process, a multiple regression analysis by SPSS 18.0 was conducted. The findings demonstrated the experience in the same business, the need for achievement, the risk-taking propensity, the preparation period for business start-up had a significant effect on self-efficacy, and experience of failure and the ratio of net worth had a significant effect on sales revenue and net profit, and the locus of control had a significant effect on outcome expectancy through the self-efficacy, a parameter. It was also noted the self-efficacy of small business owners and the business performance varied depending on the characteristics of them and the preparation process of the business start-up. Based on the those findings, the theoretical and practical implications were discussed and the suggestions about the limits of the study, future policies and studies were made.

The Associated Factors with Obesity-related Habits and Obesity index Change (비만관련 습관 및 비만도 변화에 영향을 미치는 관련요인 분석)

  • Gil, Mi-Kyeong
    • Journal of the Korean Society of School Health
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    • v.12 no.1
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    • pp.27-44
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    • 1999
  • Obesity in children is a major concern of public health. This study was performed to illuminate its effect on weight control program and the associated factors of obesity-related habits and obesity index in primary school obese children. Weight control program consisted of behavioral modification, nutrition education and exercise during 17 weeks. The sample consisted of treatment group(n=42) and control group(n=41). There was no statistical difference between the two groups in obesity index, socioeconomic status and grade. To assess the effects of weight control program, the subjects were given pre-test and post-test such as the measurement of anthropometric values and self-reporting questionnaire. This result of this study were as follows; 1. After weight control program was applied, there was a significant decrease in obesity index among the treatment group. Obesity-related habits score of the treatment group increased significantly, While there was not much difference between the pre-test and the post-test among the control group. But exercise habit didn't increase significantly in the both groups. 2. Correlation between obesity-related habits and obesity index were not evident. 3. After application of weight control program, the factors associated with change of eating habit were children's past experience of weight control, motivational change toward weight control program and friends' support for treatment group. The factors associated with change of exercise habit were post-test motivation score and friends' support. Motivational change toward weight control and pre-test self-efficacy of exercise behavior were counter-related to exercise habit. For change of other obesity-related habits, initial obesity index, motivational change, post-test self-efficacy score of exercise behavior and paternal educational status were closely associated. But post-test self-efficacy score of eating behavior was unrelated. 4. Only the factor of experience of weight control was associated with change of obesity index. 5. For the both groups, the factors associated with change of eating habits were post-test self-efficacy of eating behavior and family's support. The factors associated with change of exercise behavior were self-efficacy changes of exercise behavior and friends' support. The factors associated with change of other obesity-related habits were self-efficacy change of eating behavior. Initial obesity index was associated with change of obesity index. 6. The rate of dropouts from weight control program was 28.6% (12/42) in treatment group. Initial obesity index, other obesity-related habits except eating exercise habits, friend's support were associated with dropout. In conclusion, these results indicated that weight control program in primary school settings was effective. Direct exercise regimen and practice was demanded. In addition to the program itself, much of the success is dependent on the degree of motivation of the children involved and support provided by their parents and friends. Further study need to be performed under the condition that the weight control progrom is applied for a longer period.

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