Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Quantitative Evaluation on Laser Performance for Endovenous Photocoagulation

레이저를 이용한 하지정맥류 치료의 정량화 연구

  • Ahn, Minwoo (Department of Biomedical Engineering, Pukyong National University) ;
  • Nguyen, Van Phuc (Interdisciplinary Program of Marine-Bio, Electrical & Mechanical Engineering, Pukyong National University) ;
  • Oh, Junghwan (Department of Biomedical Engineering, Pukyong National University) ;
  • Kang, Hyun Wook (Department of Biomedical Engineering, Pukyong National University)
  • Received : 2014.05.28
  • Accepted : 2014.06.12
  • Published : 2014.06.30
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Abstract

The purpose of the study was to identify the effect of laser parameters on photocoagulation to maximize safety and efficacy during varicose vein treatment. CW and pulsed modes at 1470 nm were initially compared as a function of power on bovine liver tissue. In the pulsed mode, various parameters including repetition rate, duty cycle, and irradiation time were compared to evaluate tissue response during thermal treatment. The results demonstrated that CW and pulsed modes yielded almost similar coagulation development possibly due to shorter irradiation time of 5 sec. Regardless of laser mode, both repetition rate and duty cycle presented constant coagulation rate whereas longer irradiation time facilitated coagulation process.

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References

  1. Bradbury, A. et al., "What are the symptoms of varicose veins? Edinburgh vein study cross sectional population survey," Bmj., vol. 318, no. 7180, pp. 353-356, 1999. https://doi.org/10.1136/bmj.318.7180.353
  2. Dwerryhouse, S. et al., "Stripping the long saphenous vein reduces the rate of reoperation for recurrent varicose veins: five-year results of a randomized trial," Journal of Vascular Surgery., vol. 29, no. 4, pp. 589-592, 1999. https://doi.org/10.1016/S0741-5214(99)70302-2
  3. Navarro, L., Min, R.J., and Bone, C., "Endovenous laser: a new minimally invasive method of treatment for varicose veins-preliminary observations using an 810 nm diode laser," Dermatologic surgery., vol. 27, no. 2, pp. 117-122, 2001.
  4. Min, R.J., Khilnani, N., and Zimmet, S.E., "Endovenous laser treatment of saphenous vein reflux: long-term results," Journal of Vascular and Interventional Radiology., vol. 14, no. 8, pp. 991-996, 2003. https://doi.org/10.1097/01.RVI.0000082864.05622.E4
  5. Weiss, R.A., and Weiss, M.A., "Controlled Radiofrequency Endovenous Occlusion Using a Unique Radiofrequency Catheter Under Duplex Guidance to Eliminate Saphenous Varicose Vein Reflux: A 2-Year Follow-Up," Dermatologic surgery., vol. 28, no. 1, pp. 38-42, 2002.
  6. Darwood, R. et al., "Randomized clinical trial comparing endovenous laser ablation with surgery for the treatment of primary great saphenous varicose veins," British Journal of Surgery., vol. 95, no. 3, pp. 294-301, 2008. https://doi.org/10.1002/bjs.6101
  7. Carandina, S. et al., "Varicose vein stripping vs haemodynamic correction (CHIVA): a long term randomised trial," European Journal of Vascular and Endovascular Surgery., vol. 35, no. 2, pp. 230-237, 2008. https://doi.org/10.1016/j.ejvs.2007.09.011
  8. Sroka, R. et al., "Endovenous Laser Application," Phlebologie., vol. 42(121-129), 2013.
  9. Steiner, R., "Laser-tissue interactions," in Laser and IPL Technology in Dermatology and Aesthetic Medicine, pp. 23-36, Springer (2011).
  10. Solanki, A.B., Parikh, J.R., and Parikh, R.H., "Formulation and optimization of piroxicam proniosomes by 3-factor, 3- level Box-Behnken design," AAPS PharmSciTech., vol. 8, no. 4, pp. 43-49, 2007. https://doi.org/10.1208/pt0804086
  11. Massaki, A.B. et al., "Endoluminal laser delivery mode and wavelength effects on varicose veins in an Ex vivo model," Lasers in surgery and medicine., vol. 45, no. 2, pp. 123-129, 2013. https://doi.org/10.1002/lsm.22069