• 생명과학회지
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• 제24권11호
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• pp.1258-1267
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• 2014

가축의 고 성장률, 강건성, 질병 저항성과 같은 경제적 형질을 발굴하는 것은 매우 중요한 과제이다. 이에 경제적 형질을 발굴하기 위한 방법으로 전통적으로 RFLP, AFLP와 같은 방법이 대두되었으며, 최근 NGS 기법이 발달함에 따라 이러한 경제적 형질을 전장게놈의 수준에서 발굴하려는 노력이 계속되고 있다. 하지만, NGS 기법의 경우 상대적으로 많은 연구 비용이 필요한 실정이다. 이를 극복하기 위한 노력으로써 RNA-seq, RAD-Seq, RRL, MSG, GBS 등과 같은 기법이 활용되고 있다. 본 논문에서는 NGS 기법을 기반으로 한 최근 연구 동향을 확인하고자 하며, 특히 최소의 연구 비용으로 최대의 효과를 낼 수 있는 연구 방법을 소개하는 데 초점을 맞추었다. 또한 이러한 연구 방법이 우수한 경제형질을 가진 가축을 선정하는 데 어떻게 적용될 수 있는지에 대해 토의하였다.

• Asian-Australasian Journal of Animal Sciences
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• 제12권7호
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• pp.1015-1018
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• 1999

Single trait mixed models have been dominantly utilized for genetic evaluation of the reproductive traits in swine. However employing multiple trait approach may lead to more accurate genetic evaluations. For 5 litter size and litter weight traits of Danish Landrace, genetic parameters were estimated with a multiple trait mixed model. The heritability estimates were 0.02, 0.03, 0.03, 0.05, and 0.07, respectively for litter size at birth, litter size born alive, litter weight at birth, litter size at weaning, and litter weight at weaning. Negative genetic correlations were all positive. The litter weight at birth showed genetic antagonism with litter size born alive (-0.65) and litter size at weaning (-0.31), but positive with litter size at birth (0.47) and litter weight at weaning (0.31). The estimates of environmental correlations were larger than their corresponding genetic correlation estimates except for those between litter weight at birth and the other four traits. This study recommends simultaneous selection for two or more traits with multivariate mixed models in order to improve overall economic response.

• Journal of the Korean Data and Information Science Society
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• 제18권1호
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• pp.175-184
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• 2007

LOD scores and a permutation test for detecting and locating quantitative trait loci (QTL) from the Hanwoo economic trait have been described and we selected a considerable major BMS1167 locus for further analysis. K-means clustering analysis, for the major DNA marker mining of BMS1167 microsatellite loci in Hanwoo chromosome17, has been tried and three cluster groups divide four traits. The three cluster groups are classified according to eight DNA marker bps. Finally, we employed the bootstrap test method to calculate confidence intervals using the resampling method to find major DNA markers. We conclude that the major marker of BMS1167 locus in Hanwoo chromosome17 is only DNA marker 100bp.

• Journal of the Korean Data and Information Science Society
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• 제18권4호
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• pp.1103-1113
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• 2007

LOD scores and a permutation test for detecting and locating Quantitative trait loci(QTL) from the Hanwoo economic trait have been described and we selected a considerable major BMS941 locus. K -means clustering analysis of eight markers in BMS941 and four traits resulted in three cluster groups. Finally, we applied the bootstrap test method to calculate confidence intervals for finding major DNA markers. We conclude that the major markers of BMS941 locus in Hanwoo chromosome 17 are markers 85bp and 105bp.

• Animal Bioscience
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• 제34권4호
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• pp.471-481
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• 2021

Objective: A comprehensive study was conducted to study the effects of partition of variance on accuracy of genetic parameters and genetic trends of economic traits in Vanaraja male line/project directorate-1 (PD-1) chicken. Methods: Variance component analysis utilizing restricted maximum likelihood animal model was carried out with five generations data to delineate the population status, direct additive, maternal genetic, permanent environmental effects, besides genetic trends and performance of economic traits in PD-1 chickens. Genetic trend was estimated by regression of the estimated average breeding values (BV) on generations. Results: The body weight (BW) and shank length (SL) varied significantly (p≤0.01) among the generations, hatches and sexes. The least squares mean of SL at six weeks, the primary trait was 77.44±0.05 mm. All the production traits, viz., BWs, age at sexual maturity, egg production (EP) and egg weight were significantly influenced by generation. Model four with additive, maternal permanent environmental and residual effects was the best model for juvenile growth traits, except for zero-day BW. The heritability estimates for BW and SL at six weeks (SL6) were 0.20±0.03 and 0.17±0.03, respectively. The BV of SL6 in the population increased linearly from 0.03 to 3.62 mm due to selection. Genetic trend was significant (p≤0.05) for SL6, BW6, and production traits. The average genetic gain of EP40 for each generation was significant (p≤0.05) with an average increase of 0.38 eggs per generation. The average inbreeding coefficient was 0.02 in PD-1 line. Conclusion: The population was in ideal condition with negligible inbreeding and the selection was quite effective with significant genetic gains in each generation for primary trait of selection. The animal model minimized the over-estimation of genetic parameters and improved the accuracy of the BV, thus enabling the breeder to select the suitable breeding strategy for genetic improvement.

• Journal of the Korean Data and Information Science Society
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• 제19권3호
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• pp.867-875
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• 2008

At the period of knowledge and information in the twenty-first century, we need to produce exact data and draw up exact statistic for reasonable plans and policy which are necessary to regional growth, employment relationship, and regional welfare work. Also, we must form basis of regional statistic by producing statistic which affects on economic and social phenomenon like regonal income, unemployment rate, and business status as the basic data of these regional policy Therefore we hope much rationalization, scientification, and specialization of administrative affairs by developing the standard statistic which coincides a regional trait.

• Journal of the Korean Data and Information Science Society
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• 제15권1호
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• pp.75-81
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• 2004

We selected, in previous research, a major DNA Marker 235bp of ILSTS035 microsatellite locus in progeny test Hanwoo chromosome 6. We apply a major DNA Marker 235bp to perormance valuation Hanwoo chomosome 6. We use bootstrap BCa method and calculate confidence interval. A major DNA Marker 235bp is verified that it does not have environmental effect but affects primely economic trait factor.

• 한국가금학회지
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• 제35권2호
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• pp.163-169
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• 2008

본 연구는 한국재래닭의 1번 염색체내 존재하는 17개의 MS(microsatellite) marker를 이용하여 경제형질과 관련하여 유의적인 연관성을 가진 지역을 탐색하기 위하여 실시하였다. 1번 염색체내 경제형질과의 유의적인 연관성을 가진 지역을 탐색하기 위하여 분석된 17개의 MS marker를 대상으로 각 marker별 대립 유전자의 최다 출현 빈도를 지닌 두 개의 대립 유전자를 선발하였다. 선발된 각각의 대립 유전자는 각 경제형질별 성적을 바탕으로 고능력 집단과 저능력 집단으로 나누었으며, 두 집단간의 Chi-squire 검정을 통해 경제형질과의 연관성을 확인하였다. 분석된 결과에 따르면 난중의 경우 94 cM에 위치한 MCW0106, 1개의 지역에서 유의적인 연관성이 탐색되었다. 시산일령의 경우, 3개의 지역(ADL0234, UMA 1.125, ADL0101)에서 유의적인 연관성이 탐색되었고, 체중의 경우 6개의 지역(UMA1.117, ADL0020, UMA1.019, LAMP1, ADL0101, ADL0238)에서 유의적인 연관성이 탐색되었으며, 마지막으로 산란수의 경우 2개의 지역(ADL0101, ADL0238)에서 유의적인 연관성을 확인하였다. ADL0101는 시산일령, 체중 그리고 산란수에서의 유의적인 연관성이 확인되었으며, 산란수에서는 두개의 대립 유전자(174, 178) 모두에서 유의적인 연관성이 탐색되었음을 확인하였다.

• Asian-Australasian Journal of Animal Sciences
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• 제8권4호
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• pp.375-378
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• 1995

Three month old 600 ducklings of Khaki Campbell/KC Desi and KC X Desi were reared for a period of 13 months in the villages surrounding Bangladesh Agricultural University in order to study the economic traits of duck with and without extra feed to scavenging system of rearing. KC attained earlier sexual maturity followed by KC X Desi and Desi ducks and crossbred showed closeness to sire breed for this trait, KC X Desi found heavier and produce more eggs than their parental breeds. KC showed higher hatchability followed by KC X Desi and Desi ducks were more resistant followed by KC X Desi and KC to diseases. Extra feeding were found more beneficial to ducks irrespective of breed and types.

• 한국생명과학회:학술대회논문집
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• 한국생명과학회 2008년도 제49회 학술심포지움 및 국제학술대회
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• pp.91.1-91.1
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• 2008