• The Journal of the Convergence on Culture Technology
• /
• v.4 no.3
• /
• pp.247-252
• /
• 2018

The problem of the environment is urgently coming to the world as a problem that humanity must solve. In particular, Korea is directly affected by air pollution and marine pollution due to its geopolitical position with China, and is also exposed to a great deal of pollution due to air, water, soil, and weather. In this situation, due to the disconnection between the management domain / service (system) related to the environment, the ability to quickly identify causes and cope with situations in the event of environmental pollution or disasters is weak, and duplication and investment are being faced. The development of a service platform for smart environment disaster management is designed to detect environmental disasters in an early stage through the management of smart environment disaster management at the national level, It will be a way to predict complex environmental disasters.

• Journal of the Korean Geographical Society
• /
• v.1
• /
• pp.67-82
• /
• 1963

This paper examined the settlement and evolution of the Namdo Food Festival holding in Nakan folk village since 1994. The Namdo Food Festival is a representative event tourism in Chonnam which beautifully displays Nakan eup-sung's folk landscape and Namdo's traditional food, a prime tourist resource. Since 1994, the Namdo Food Festival has steadily evoloved in the scale aspects of the program budget, and the number of visitors participating in festiva. In addition, the period of the food festival was fixed for a week, early in October. The majority of visitors to the festival was from Kwangju. Moreover, visitors from other provinces have steadily increased, in particular visitors from Yeongnam province such as Pusas and Kyeongnam provinces have increased since 1996. In order to settle down and develop the Namdo Food Festival, the followings should be done change of the ownership from public to private sector, training of professional entertainers, development of programs which can reinforce historical aspects and placeness of Nakan folk village, adoption of management technoques for the local economic activities, and extension of linkage with tourists places around Nakan folk village, reflection of tourists interests and needs through a continuoua tourist's behaviour analysis.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
• /
• v.30 no.1
• /
• pp.97-104
• /
• 2012

In this paper, the GPS precipitable water vapor was retrieved by estimating of GPS signal delay in the troposphere during the progress of heavy snowfall on the Gangwon Province, 2011. For this period, the time series analysis between GPS precipitable water vapor and fresh snow depth was accomplished. The time series and the comparison with the GPS precipitable water vapor and the fresh snow depth indicates that the temporal change of two variations is closely related to the progress of the heavy snowfall. Also, the periodicity of GPS precipitable water vapor using the wavelet transform method was showed a similar cycle of saturated water vapor pressure as the limitation of this study span. The result shows that the decrement of GPS precipitable water vapor was conflicted with the increment of fresh snow depth at two sites, Gangneung and Uljin. The correlation between the GPS precipitable water vapor and the saturated water vapor pressure for the event was showed a positive correlation, compare with the non-heavy snowfall periods.

• Journal of Preventive Medicine and Public Health
• /
• v.43 no.2
• /
• pp.99-104
• /
• 2010

The World Health Organization (WHO) announced the emergence of a novel influenza on April 24, 2009, and they declared pandemic on June 11. In Korea, the proportion of influenza-like illness and the consumption of antiviral agents peaked in early November. The government established the Central Headquarters for Influenza Control and operated the emergency response system. In the quarantine stations, we checked the body temperature and collected quarantine questionnaires from all the arrivals from infected countries. We also isolated the confirmed cases in the national isolation hospitals. However, as the community outbreaks were reported, we changed strategy from containment to mitigation. We changed the antiviral agent prescription guideline so that doctors could prescribe antiviral agents to all patients with acute febrile respiratory illness, without a laboratory diagnosis. Also the 470 designated hospitals were activated to enhance the efficacy of treatment. We vaccinated about 12 million people and manage the adverse event following the immunization management system. In 2010, we will establish additional national isolation wards and support hospitals to establish fever clinics and isolation intensive care unit (ICU) beds. We will also make a computer program for managing the national isolation hospitals and designated hospitals. We will establish isolation rooms and expand the laboratory in quarantine stations and we will construct a bio-safety level 3 laboratory in each province. In addition, we plan to construct a bio-safety level 4 laboratory at a new Korea Centers for Disease Control and Prevention (KCDC) facilities in Ossong.

• Korean Journal of Veterinary Research
• /
• v.54 no.4
• /
• pp.225-231
• /
• 2014

Klotho deficiency is an early event in acute kidney injury (AKI) that exacerbates acute kidney damage. The present study explored the expression of Klotho and inflammation related factors in cisplatin-induced AKI. Rats (n = 18) were treated with cisplatin intraperitoneal injection (5 mg/kg) or left untreated as controls (n = 6), then sacrificed at 5 (n = 6) and 10 days (n = 6) treatment. Five days after cisplatin injection, the serum kidney enzymes and kidney cell apoptosis were significantly increased. Moreover, the expression of Klotho was decreased when compared to the control group, especially in the cortex and outer medulla regions. In contrast, inflammation related signals including nuclear factor kappa B, tumor necrosis factor-${\alpha}$, and tumor necrosis factor-like weak inducer of apoptosis were enhanced. However, 10 days after cisplatin injection, Klotho expression was enhanced upon both IHC and Western blot analysis, with slightly recovered renal function and decreased apoptosis. Furthermore, inflammation related signals expression was decreased relative to the 5 days group. Overall, this study confirmed the opposite expression patterns between Klotho and inflammation related signals and their localization in cisplatin-induced AKI kidney.

• The Journal of the Petrological Society of Korea
• /
• v.11 no.3_4
• /
• pp.121-137
• /
• 2002

Metamorphic evolution of the Ogcheon metamorphic belt has been studied by many investigators for the past few decades. P-T conditions of the Ogcheon metamorphic belt were estimated as 4.2-9.4 kbar and $490-630^{\circ}C$, corresponding to the medium-pressure type. In addition, the clockwise P-T-t path suggests a crustal-thickening event in association with the formation of thrust nappes. However, some details on deformation and orogeny of the Ogcheon metamorphic belt have been ambiguous yet. Although the metamorphic age has been also equivocal, recent isotopic studies strongly suggest that the peak metamorphism in the Ogcheon metamorphic belt has occurred at ca. 300-280 Ma between Late Carboniferous and Early Permian. It is thus inferred that the Ogcheon metamorphic belt and the Taebaegsan basin have evolved as separate terranes and that both were sutured at ca. 250-220 Ma. These results are partly in contrast with those of previous workers and require a revised framework for tectonic evolution of the Ogcheon belt. In addition, it is likely that the Ogcheon belt is correlative with the Hida marginal belt and the Hida metamorphic belt.

• Journal of Korean Neurosurgical Society
• /
• v.58 no.3
• /
• pp.197-204
• /
• 2015

Objective : Aneurysms arising from the pericallosal artery (PA) are uncommon and challenging to treat. The aim of this study was to report our experiences of the endovascular treatment of ruptured PA aneurysms. Methods : From September 2003 to December 2013, 30 ruptured PA aneurysms in 30 patients were treated at our institution via an endovascular approach. Procedural data, clinical and angiographic results were retrospectively reviewed. Results : Regarding immediate angiographic control, complete occlusion was achieved in 21 (70.0%) patients and near-complete occlusion in 9 (30.0%). Eight procedure-related complications occurred, including intraprocedural rupture and early rebleeding in three each, and thromboembolic event in two. At last follow-up, 18 patients were independent with a modified Rankin Scale (mRS) score of 0-2, and the other 12 were either dependent or had expired (mRS score, 3-6). Adjacent hematoma was found to be associated with an increased risk of poor clinical outcome. Seventeen of 23 surviving patients underwent follow-up conventional angiography (mean, 16.5 months). Results showed stable occlusion in 14 (82.4%), minor recanalization in two (11.8%), and major recanalization, which required recoiling, in one (5.9%). Conclusion : Our experiences demonstrate that endovascular treatment for a ruptured PA aneurysms is both feasible and effective. However, periprocedural rebleedings were found to occur far more often (20.0%) than is generally suspected and to be associated with preoperative contrast retention. Analysis showed existing adjacent hematoma is predictive of a poor clinical outcome.

• Proceedings of the KSAR Conference
• /
• 2003.06a
• /
• pp.61-61
• /
• 2003

We have investigated the novel function of tissue transglutaminase (tTG) in the germinal vesicle breakdown (GVBD) of mouse oocyte. tTG was identified in ooplasm and germinal vesicle by immunostaining assay. Spontaneous maturation of the oocytes elevated in situ activity of tTG by over 2.5 fold at 3 hr, which was determined by a confocal microscopic assay. However, incubation with monodansylcadaverine (MDC), a tTG inhibitor, blocked the activation of tTG. The possible role of tTG in GVBD was investigated by the use of two tTG inhibitors, MDC and cystamine. MDC largely inhibited the GVBD by a concentration dependent manner. GV-stage oocytes were matured to the GVBD stage by 78% at 3 hr in BWW culture medium. However, in the oocytes incubated with MDC for 3 hr, the GVBD rates were 43 and 11% by 50 and 100 mM, respectively. MDC also blocked the entry of 70 kDa TRITC-dextran from the ooplasm to the compartment of germinal vesicle, indicating a possible inhibition of nuclear pore disassembly by MDC. The role of tTG in GVBD was further investigated by microinjection with cystamine. The control oocytes, injected with DPBS, showed about 80 % of GVBD at 3 hr. But the oocytes injected with cystamine showed 15% of GVBD at 3 hr and a little higher rate at 6 hr. In addition, the inhibition of GVBD maturation by MDC was reversible by washing. These results suggested that tTG was involved in the early event of mouse oocyte maturation

• The Korean Journal of Health Service Management
• /
• v.6 no.1
• /
• pp.27-38
• /
• 2012

This study is to find out the correlation among the predisposing, enabling, and need factors in Anderson Behavioral Model using the data from Korea Medical Panel Survey conducted in the early part (April 1 - October 31) of 2008. The findings are as follows. It was found that the utilization rate of western medical service was far higher. the influential factor to choose western or oriental medical service taking western medical institutions as the reference group, the influential factor to choose oriental medical institution has significantly increased when the patient who have covered by medical insurance has one accompanied disease and their age was between 45 - 74, compared to the people less than 45 years old. It also increased when the age of the patient was between 45-54 years old, and in the event those who are not covered by medical insurance have accompanied disease and that the disease mobility period is 2-4 years. reviewing the several characteristics of the utilization of western and oriental medical services by the patient with musculoskeletal system disorders, the number of accompanied disease is an influential factor for the utilization of oriental medical services. And, disease mobility period is a significant factor for the utilization of both western and oriental medical services together, though it is not identified in this study. Therefore, it is expected that mutual cooperation between western and oriental medical services is more required for the patient with musculoskeletal system disorders as the aging society rapidly develops. In order to foster oriental medicine, it is required to specialize in competitive disease such as musculoskeletal system disorders.

• Asian-Australasian Journal of Animal Sciences
• /
• v.20 no.7
• /
• pp.1030-1038
• /
• 2007

Results on localization of growth hormone receptor (GHR), interaction of growth hormone (GH) with receptor in buffalo adipose tissue and identification of activated signaling molecules in the action of GH are presented. Bovine GH (bGH) was labeled with fluorescein or biotin. Fluorescein-labelled bGH was used for localization of GHRs in buffalo adipocytes. The receptors were present on the cell surface. The affinity of binding of GH to its receptor was determined by designing an experiment in which buffalo adipose tissue explants, biotinylated GH and streptavidin-peroxidase conjugate were employed. The affinity constant was calculated to be $2{\times}10^8M^{-1}$. The receptor density on adipose tissue was found to be 1 femto mole per mg of tissue. Signalling molecules generated in the action of GH were tentatively identified by employing Western blot and enhanced chemiluminescence techniques using anti-phosphotyrosine antibody. Based on molecular weights of proteins reactive to anti-phosphotyrosine antibody, three signaling molecules viz. insulin receptor substrate, Janus activated kinase (Jak) and mitogen activated protein were tentatively identified. These signaling molecules appeared in a time (incubation time of explants with growth hormone) dependent way. The activation of Jak2 was confirmed by employing anti-Jak2 antibody in a Western blot. The activation of Jak2 occurred during 5 min incubation of buffalo adipose tissue explants with GH and incubation for an additional period, viz. 30 min. or 60 min., resulted in a drastic reduction in activation. The results suggest that Jak2 activation is an early event in the action of GH in buffalo adipose tissue.