• Title/Summary/Keyword: eIF

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Effects of Ojeoksangamibang on the Lipid Metabolism, Anti-oxidation and Concentration of Proinflammatory Cytokines in Rat Fed High Fat Diet (오적산가미방(五積散加味方)이 고지방식이 유도 비만쥐의 지질대사, 항산화계 및 전염증성 cytokine 생산에 미치는 영향)

  • Kong, In-Pyo;Park, Won-Hyung;Cha, Yun-Yeop
    • Journal of Korean Medicine Rehabilitation
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    • v.21 no.4
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    • pp.23-40
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    • 2011
  • Objectives: This study was designed to examine the effects of extracts of Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) on the lipid lowering, anti-oxidation and concentration of proinflammatory cytokines and was investigated on hyperlipidemic rats. Methods: Male rats weighing $182.39{\pm}4.71g$ were fed high fat diet for 8 weeks and 36 rats(above 400 g) were divided into 4 groups. Each of 9 rats was divided a control group and experimental groups. We fed a control group of rats a basal diet and administered normal saline(100 mg/kg, 1 time/1 day) for 4 weeks. And we fed each experimental group of rats basal diet and administered an extract of Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) extracts(100 mg/kg, 200mg/kg, 300 mg/kg, 300 mg/kg, 1 time/1 day) for 4 weeks. At the end of the experiment, the rats were sacrificed to determine their chemical composition. We measured lipid of plasma and liver, concentration of proinflmmatory cytokines, anti-oxidative activity and $TNF-{\alpha}$, Apo-B, Apo-E and leptin gene expression. Results: 1. Concentration of plasma free fatty(FFA) showed no significant difference in all the treatment groups. Concentration of plasma triglyceride(TG) showed a significant decrement in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. 2. Concentration of plasma total cholesterol showed a significant decrement in the 200 and 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. Concentration of plasma low density lipoprotein(LDL)-cholesterol showed a Significant decrement in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. Concentration of plasma high density lipoprotein(HDL)-cholesterol showed a significant increment in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) group. 3. Concentration of liver total cholesterol showed a tendence to decrease in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups. Concentration of liver TG showed a significant decrement in all Ojeoksangamibang groups than that of control group. 4. Concentration of plasma and liver thiobarbituric acid reactive substance(TBARS) showed a tendence to decrease in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups. 5. The values of glutathione peroxidase(GSH-Px), superoxide dismutase(SOD) and catalase(CAT) activity showed a significant increment in all Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. 6. The values of plasma aspartate aminotransferase(AST) and alanine aminotransferase(ALT) activity showed no significant different in all treatment group. 7. Concentration of plasma $interleukin(IL)-1{beta}$ showed no significant difference in all the treatment groups. Concentration of plasma IL-6 showed a significant decrement in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) group than that of control group. Concentration of plasma tumor necrosis $factor-{\alpha}(TNF-{\alpha})$ a siginifant decrement in the 200 and 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) group than that of control group. However the concentration of plasma IL-10 in the 300 mg/kg Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups showed a significant increment than that of control group. 9. In the analysis of reverse transcription-polymerase chain reaction(RT-PCR), gene expression of $TNF-{\alpha}$, Apo-B and Apo-E in the Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups showed a lower expression than that of control group. However the gene expression of leptin showed no difference in the treatment groups. 10. The ratio of $TNF-{\alpha}$, Apo-B, and Apo-E per ${\beta}-actin$ expression in the Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups showed a significant decrement than that of control group. However The ratio of leptin expression per ${\beta}-actin$ expression showed no significant difference among all the treatment groups. Conclusions: According to above results, in lowering lipid effect, anti-oxidation and control of pro-inflammatory cytokines production, Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) gives effect.

INJECTIVE PROPERTY OF LAURENT POWER SERIES MODULE

  • Park, Sang-Won
    • East Asian mathematical journal
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    • v.17 no.2
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    • pp.367-374
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    • 2001
  • Northcott and McKerrow proved that if R is a left noetherian ring and E is an injective left R-module, then $E[x^{-1}]$ is an injective left R[x]-module. Park generalized Northcott and McKerrow's result so that if R is a left noetherian ring and E is an injective left R-module, then $E[x^{-S}]$ is an injective left $R[x^S]$-module, where S is a submonoid of $\mathbb{N}$($\mathbb{N}$ is the set of all natural numbers). In this paper we extend the injective property to the Laurent power series module so that if R is a ring and E is an injective left R-module, then $E[[x^{-1},x]]$ is an injective left $R[x^S]$-module.

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A Study on the Implementation and Performance Analysis of Software Based GPS L1 and Galileo E1/E5a Signal Processing (소프트웨어 기반의 GPS L1 및 갈릴레오 E1/E5a 신호 처리 구현 및 성능에 관한 연구)

  • Sin, Cheon-Sig;Lee, Sang-Uk;Yoon, Dong-Won;Kim, Jae-Hoon
    • Journal of Advanced Navigation Technology
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    • v.13 no.3
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    • pp.319-326
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    • 2009
  • In this paper, the key technologies of Navigation receiver for GNSS sensor station are presented as a development result of a GNSS ground station in ETRI. A wide-band antenna and RF/IF components and SW signal processing unit to cover the GPS and Galileo signals for GNSS receiver are developed and its performance is verified by using GPS live signal and GNSS RF signal simulator from SpirentTM. We also gather GIOVE-A signal by using H/W antenna and RF/IF units in IF-level as sampling frequency and bit number, 112MHz and 8bits, respectively by using the developed wide-band antenna and RF/IF components. Data acquisition is done by using commercial data acquisition device from National Instrument TM. The gathered data is fed into SW receiver to process Galileo E1 to verify Galileo signal processing by Galileo live signal from GIOVE-A.

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TWO GENERALIZATIONS OF LCM-STABLE EXTENSIONS

  • Chang, Gyu Whan;Kim, Hwankoo;Lim, Jung Wook
    • Journal of the Korean Mathematical Society
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    • v.50 no.2
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    • pp.393-410
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    • 2013
  • Let $R{\subseteq}T$ be an extension of integral domains, X be an indeterminate over T, and R[X] and T[X] be polynomial rings. Then $R{\subseteq}T$ is said to be LCM-stable if $(aR{\cap}bR)T=aT{\cap}bT$ for all $0{\neq}a,b{\in}R$. Let $w_A$ be the so-called $w$-operation on an integral domain A. In this paper, we introduce the notions of $w(e)$- and $w$-LCM-stable extensions: (i) $R{\subseteq}T$ is $w(e)$-LCM-stable if $((aR{\cap}bR)T)_{w_T}=aT{\cap}bT$ for all $0{\neq}a,b{\in}R$ and (ii) $R{\subseteq}T$ is $w$-LCM-stable if $((aR{\cap}bR)T)_{w_R}=(aT{\cap}bT)_{w_R}$ for all $0{\neq}a,b{\in}R$. We prove that LCM-stable extensions are both $w(e)$-LCM-stable and $w$-LCM-stable. We also generalize some results on LCM-stable extensions. Among other things, we show that if R is a Krull domain (resp., $P{\upsilon}MD$), then $R{\subseteq}T$ is $w(e)$-LCM-stable (resp., $w$-LCM-stable) if and only if $R[X]{\subseteq}T[X]$ is $w(e)$-LCM-stable (resp., $w$-LCM-stable).

SURFACES FOLIATED BY ELLIPSES WITH CONSTANT GAUSSIAN CURVATURE IN EUCLIDEAN 3-SPACE

  • Ali, Ahmed T.;Hamdoon, Fathi M.
    • Korean Journal of Mathematics
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    • v.25 no.4
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    • pp.537-554
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    • 2017
  • In this paper, we study the surfaces foliated by ellipses in three dimensional Euclidean space ${\mathbf{E}}^3$. We prove the following results: (1) The surface foliated by an ellipse have constant Gaussian curvature K if and only if the surface is flat, i.e. K = 0. (2) The surface foliated by an ellipse is a flat if and only if it is a part of generalized cylinder or part of generalized cone.

INTERPOLATION PROBLEMS FOR OPERATORS WITH CORANK IN ALG L

  • Kang, Joo-Ho
    • Honam Mathematical Journal
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    • v.34 no.3
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    • pp.409-422
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    • 2012
  • Let $\mathcal{L}$ be a subspace lattice on a Hilbert space $\mathcal{H}$. And let X and Y be operators acting on a Hilbert space $\mathcal{H}$. Let $sp(x)=\{{\alpha}x\;:\;{\alpha}{\in}\mathcal{C}\}$ $x{\in}\mathcal{H}$. Assume that $\mathcal{H}=\overline{range\;X}{\oplus}sp(h)$ for some $h{\in}\mathcal{H}$ and < $h$, $E^{\bot}Xf$ >= 0 for each $f{\in}\mathcal{H}$ and $E{\in}\mathcal{L}$. Then there exists an operator A in Alg$\mathcal{L}$ such that AX = Y if and only if $sup\{\frac{{\parallel}E^{\bot}Yf{\parallel}}{{\parallel}E^{\bot}Yf{\parallel}}\;:\;f{\in}H,\;E{\in}\mathcal{L}\}$ = K < ${\infty}$. Moreover, if the necessary condition holds, then we may choose an operator A such that AX = Y and ${\parallel}||A{\parallel}=K$.

SOLVING OPERATOR EQUATIONS Ax = Y AND Ax = y IN ALGL

  • LEE, SANG KI;KANG, JOO HO
    • Journal of applied mathematics & informatics
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    • v.33 no.3_4
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    • pp.417-424
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    • 2015
  • In this paper the following is proved: Let L be a subspace lattice on a Hilbert space H and X and Y be operators acting on a Hilbert space H. If XE = EX for each E ${\in}$ L, then there exists an operator A in AlgL such that AX = Y if and only if sup $\left{\frac{\parallel{XEf}\parallel}{\parallel{YEf}\parallel}\;:\;f{\in}H,\;E{\in}L\right}$ = K < $\infty$ and YE=EYE. Let x and y be non-zero vectors in H. Let Px be the orthogonal pro-jection on sp(x). If EPx = PxE for each E $\in$ L, then the following are equivalent. (1) There exists an operator A in AlgL such that Ax = y. (2) < f, Ey > y =< f, Ey > Ey for each E ${\in}$ L and f ${\in}$ H.

MONOIDS OVER WHICH ALL REGULAR RIGHT S-ACTS ARE WEAKLY INJECTIVE

  • Moon, Eunho L.
    • Korean Journal of Mathematics
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    • v.20 no.4
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    • pp.423-431
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    • 2012
  • There have been some study characterizing monoids by homological classification using the properties around projectivity, injectivity, or regularity of acts. In particular Kilp and Knauer([4]) have analyzed monoids over which all acts with one of the properties around projectivity or injectivity are regular. However Kilp and Knauer left over problems of characterization of monoids over which all regular right S-acts are (weakly) at, (weakly) injective or faithful. Among these open problems, Liu([3]) proved that all regular right S-acts are (weakly) at if and only if es is a von Neumann regular element of S for all $s{\in}S$ and $e^2=e{\in}T$, and that all regular right S-acts are faithful if and only if all right ideals eS, $e^2=e{\in}T$, are faithful. But it still remains an open question to characterize over which all regular right S-acts are weakly injective or injective. Hence the purpose of this study is to investigate the relations between regular right S-acts and weakly injective right S-acts, and then characterize the monoid over which all regular right S-acts are weakly injective.

ON B-ALGEBRAS AND GROUPS

  • Usan, Janez;Zizovic, Malisa
    • East Asian mathematical journal
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    • v.18 no.2
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    • pp.205-209
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    • 2002
  • In the paper the following propositions are proved. 1) If ($Q,{\cdot},e$) is a B-algebra, then there exists a group($Q,A,^{-1}$, 1) such that the following equalities hold e=1 and ${\cdot}=^{-1}A$, where $^{-1}A(x,y)=z{\Longleftrightarrow^{def}}A(z,y)=x$; and 2) If ($Q,A,^{-1}$, e) is a group, then ($Q,^{-1}A$, e) is a B-algebra.

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Injective Property Of Generalized Inverse Polynomial Module

  • Park, Sang-Won
    • Communications of the Korean Mathematical Society
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    • v.15 no.2
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    • pp.257-261
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    • 2000
  • Northcott and Mckerrow proved that if R is a left noe-therian ring and E is an injective left R-module, then E[x-1] is an injective left R[x]-module. In this paper we generalize Northcott and McKerrow's result so that if R is a left noetherian ring and E is an in-jective left R-module, then E[x-S] is an injective left R[xS]-module, where S is a submonoid of N (N is the set of all natural numbers).

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