• Educational Technology International
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• v.9 no.1
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• pp.49-77
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• 2008

As clearly suggested in the case of Wikipedia, collective intelligence is predicted to develop into the most important platform of knowledge and information in the future society. But it just remains at the level of activities for group projects in the present frame of education and so it doesn't lead to creating collective intelligence. This study looks into an 'information repository model of collective intelligence' that makes it possible to deliver an education process a priori of Shared Knowledge Reservoir to "Junior Digital Nomad", who is definitely and will be in existence, and that further enables them to be active there in reality. Based on this storage model, it suggests a practicable web system model; Junior Maphistory e-encyclopedia, which is appropriately consistent with the features of Web 2.0 and can grow into a general historical and geographical information service.

• Korean Journal of Heritage: History & Science
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• v.56 no.2
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• pp.28-45
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• 2023

Although we have entered the era of digital transformation, there is currently no system that efficiently collects, manages, integrates, and services a large number of archaeological digital source materials produced as a result of cultural relics research, i.e., an intelligent integrated management and service platform for archaeological academic information. In this regard, the need to build a digital dictionary of Korean archaeology was confirmed by examining the problem of the Digital Encyclopedia of Korean Archaeology, which is currently available in PDF format on the web, the current status of the publication and use of the Dictionary of Korean Archaeology, and the cases of building digital platforms at home and abroad. Therefore, this paper aims to suggest a general direction for creating a digital encyclopedia of Korean archaeology based on the Dictionary of Korean Archaeology, which includes quality knowledge information, to reconsider the accessibility of archaeological data in conformity with data access limitations. The application of the series Dictionary of Korean Archaeology, published since 2001, and the necessity for digital transformation were examined, as well as the application of data from the archaeological data archiving platforms of Europe, the USA, Japan, and cases of establishing platforms corresponding to specialized encyclopedias from Korea. Based on these, a three-step implementation plan and detailed projects were suggested to create the Digital Encyclopedia of Korean Archaeology. Through this, we proposed the design of metadata for computerized records and the expansion to semantic (meaning-based) data that gives and shows the relationship information between the produced metadata as the implementation tasks to build the Digital Dictionary of Korean Archaeology. It is hoped that such research will help create an integrated intelligent management and service platform for archaeology, raise awareness, and provide a better understanding of Korean archaeology to the general public.

• Cross-Cultural Studies
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• v.33
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• pp.143-169
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• 2013

Recently, because of the danger and damages that following the steady development of scientific technologies, natural science is faced with many humane and ethical problems. So it is asserted the interdisciplinary with social and human science. However, it comes commonly that the ethical issues such as world view and one's view of life caused the development of sociology, especially development of the market economy. But in many cases, the interdisciplinary can be useful for widen the view of scholars. The interdisciplinary is actually connected with the problems of philosophy, and located in that domain. In this case, this is noticed as a model to the philosophers in 18th century, especially Denis Diderot. Diderot published De $l^{\prime}interpr{\acute{e}}tation$ de la nature during editing the Encyclopedia, from there he picked out the contents from piles of documents of Encyclopedia. Even though the contents or opinions of De $l^{\prime}interpr{\acute{e}}tation$ de la nature are inaccuracy or erroneous, it shows that how human-social science and natural science encountered. Diderot studied mathematics and then Diderot accepted to the natural science proposal, he approaches philosophy with translate English books to the French. Next he understood natural science by reading Buffon and Maupertuis, and during working for Encyclopedia, he possessed his knowledge that he can claim his opinion to other scholars. However in this De $l^{\prime}interpr{\acute{e}}tation$ de la nature, Diderot who sometimes rebutted other scholars' theory and demonstration, tried to build a philosophy on metaphysics in order to it was important for himself that he imposed the methods of science and importance of experience. Anyhow, this De $l^{\prime}interpr{\acute{e}}tation$ de la nature cause consider the recognition of Diderot in the field of natural science, and is suggested as a model about his Nature. This mean that it is an expression of his philosophy, and the content is found from natural philosophy and empirical philosophy. Like giving these attache the importance of method study for science and technique, these are targeted the promotion of popularization of natural-science and scientific-technology. Also it advocates fulfilling from reasonable philosophy to empirical philosophy. Therefore, the philosophy which was speculative and abstracted became his philosophy which was writing the meaning, as waiting the discovery of science. And at that time, the humanities made interdisciplinary with natural science.

• Journal of Animal Science and Technology
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• v.66 no.4
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• pp.702-716
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• 2024

The objective of this study was to identify genomic regions and candidate genes associated with productive traits using a total of 37,099 productive records and 6,683 single nucleotide polymorphism (SNP) data obtained from five Great-Grand-Parents (GGP) farms in Landrace. The estimated of heritabilities for days to 105 kg (AGE), average daily gain (ADG), backfat thickness (BF), and eye muscle area (EMA) were 0.49, 0.49, 0.56, and 0.23, respectively. We identified a genetic window that explained 2.05%-2.34% for each trait of the total genetic variance. We observed a clear partitioning of the four traits into two groups, and the most significant genomic region for AGE and ADG were located on the Sus scrofa chromosome (SSC) 1, while BF and EMA were located on SSC 2. We conducted Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG), which revealed results in three biological processes, four cellular component, three molecular function, and six KEGG pathway. Significant SNPs can be used as markers for quantitative trait loci (QTL) investigation and genomic selection (GS) for productive traits in Landrace pig.

• 한국산학경영학회:학술대회논문집
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• 2004.11a
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• pp.4-22
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• 2004

The Internet provides a new distribution channel of digital contents for conventional media firms such as newspaper, magazine and encyclopedia publishers and broadcasting companies with very low marginal production and distribution cost. In comparison to traditional offline channel, there have been various revenue models in online content markets such as advertising model, subscription model, affiliation fee model, etc. In the earlier of the Internet era, most of online content firms provided their services free in order to boost offline revenue or they depend on advertising revenue sources in lieu of attaining revenue from their contents. However, as many online content firms are confronted with many difficulties in attaining revenues from online advertising model, they began to charge their contents. This paper shows why they charge their contents and explores entry conditions when conventional firms enter online content markets. And also this paper discusses managerial implications related to pricing strategies in online content markets.

• Journal of Sasang Constitutional Medicine
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• v.19 no.3
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• pp.20-29
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• 2007

1. Objectives We know that the origine of the pe-tsai is from 백채(白菜; pronounced as bak-tsai, meaning white vegetable). But some literatures said that the japanese butterbur(Petasites japonicus (Sieb. et Zucc.) Maxim) is from 백채(白菜;: pronounced as bak-tsai), too. These two words have same origin. It makes us get into a mess. So We are about to study the origine of the pe-tsai more. Also, we investigated its historical origin, properties and Sasang constitutional medicine's efficacy. 2. Methods We reviewed farmings(e.g. 山林經濟, 林園經濟法), dictionarys(e.g. 訓蒙字會), encyclopedia(e.g. 物名攷), books on herbs and medicines to summarize literatures about the pe-tsai. 3. Results and Conclusions (1) The origin of term, pe-tsai is sung, named after a pine tree(松), chineses character pronounced as song) which we can see throughout a year. Also, pe-tsai was called white vegetables(白菜, pronounced as bak-tsai) because its appearance is green and white. Therefore, the pronounciation of sung derives from its character and we also say bak-tsai(白菜), which came from its looks. (2) Today we pronounce pe-tsai inro bae-tsu(배추) in korean. There are pronunciational developments of this word : bak-tsai(白菜) $\to$ bae-tsae $\to$ bae-tsa $\to$ bae-tsa $\to$ bae-tsae(배채) $\to$ bae-tsu(배추). (3) Our ancestor used bak-tsai(白菜) as the name of japenese butterbur, which was different from China. The latter times of Joseon(조선), however, sometimes bak-tsai(白菜) meant pe-tsai. After the year of 1800, bak-tsai(白菜) only meant pe-tsai. So when we try to translate our ancestor's books, we must examine carefully their published year. (4) Pe-tsai is used for baby's erysipelas, boil, fever in the chest, thirst after alcohol drinking and kind of diabetes. It helps digestive organs as well. Pe-tsai is used for stress, fever in the chest and cough with fever of Soyangin and Tayangin in Sasang Constitutional Medicine.

• The Journal of Korean Academy of Prosthodontics
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• v.55 no.4
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• pp.361-371
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• 2017

Purpose: We aimed to investigate the gene expression of human gingival fibroblasts on microgroove surface using DNA microarray. Materials and methods: Microgrooves were applied on grade II titanium discs to have 0/$0{\mu}m$ (NE0, control group), 60/$10{\mu}m$ (E60/10, experimental group) of respective width/depth by photolithography. The entire surface of the microgrooved Ti substrata was further acid etched and used as the two experimental groups in this study. Human gingival fibroblasts were cultured in the experimental group and the control group, and total RNA was extracted. The oligonucleotide microarray was performed to confirm the changes of various gene expression levels between experimental group and control group. Changes of gene expression level were determined at the pathway level by mapping the expression results of DNA chips, using the KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway analysis. Results: Gene expression levels on E60/10 and NE0 were analyzed, there were 123 genes showing significant differences in expression more than 1.5 times on E60/10 microgrooved surface compared to NE0 surface, and 19 genes showing significant differences in expression more than 2 times. The KEGG pathway analysis confirmed the changes in gene expression levels under experimental conditions. Cell signaling, proliferation, and activity among the various gene expression results were identified. Conclusion: Microgrooved surfaces induce gene expression changes and related cell signaling. According to the results of this study, microgrooves can be used as the surface of various biomaterials which need to improve cell activity through gene expression changes and activation of cell signaling.

• Genomics & Informatics
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• v.12 no.1
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• pp.2-11
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• 2014

After the initial enthusiasm of the human genome project, it became clear that without additional data pertaining to the epigenome, i.e., how the genome is marked at specific developmental periods, in different tissues, as well as across individuals and species-the promise of the genome sequencing project in understanding biology cannot be fulfilled. This realization prompted several large-scale efforts to map the epigenome, most notably the Encyclopedia of DNA Elements (ENCODE) project. While there is essentially a single genome in an individual, there are hundreds of epigenomes, corresponding to various types of epigenomic marks at different developmental times and in multiple tissue types. Unprecedented advances in next-generation sequencing (NGS) technologies, by virtue of low cost and high speeds that continue to improve at a rate beyond what is anticipated by Moore's law for computer hardware technologies, have revolutionized molecular biology and genetics research, and have in turn prompted innovative ways to reduce the problem of measuring cellular events involving DNA or RNA into a sequencing problem. In this article, we provide a brief overview of the epigenome, the various types of epigenomic data afforded by NGS, and some of the novel discoveries yielded by the epigenomics projects. We also provide ample references for the reader to get in-depth information on these topics.

• Journal of the Korean Home Economics Association
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• v.40 no.7
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• pp.69-82
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• 2002

The objective of this study was to develop a Web based learning environment for Home Economics Education(HEE) using ICT (Information & Communication Technology). For the study, the following procedures were performed: 1) the review of literature, 2) development of teaming environment and questionnaires based on Web for HEE using ICT. The Web based learning environment was investigated and designed, and evaluated by the users. The problems indicated through the evaluation were revised and complemented. In addition, 13 sets of Learning questionnaires, which were verified using the same procedure as above, were developed to provide problem solving ability through the Web based learning environment. Learning environment based on the Web entitled "Together with the classroom of HEE" has a main menu, which is composed of rooms for HEE, students, teachers, various topics, recommendation sites, chatting, and e-mail. A room for HEE, in which teaming activity mainly occurs by following the sequences of learning procedures, includes other sub-rooms for the guidance of Loaming, discussion, directories for reference, question and answer, submission of homework, evaluation, and an encyclopedia. Therefore, this study implicates: 1) achievement of teaming environment using the ICT mainly made by students who solve problems closely related to daily life, 2) development of practical learning questionnaires fitted in the present state, 3) preparation for the curriculum. Finally, from this study, I suggested that further studies are needed to develop models for learning, interaction between students and teachers, and the learning materials under the Web based loaming environment.

• Genomics & Informatics
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• v.18 no.4
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• pp.37.1-37.11
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• 2020

BET inhibitor, as an epigenetic regulator inhibitor, reduces the expression of oncogenes such as Myc and Bcl-2, which affects cancer growth and development. However, it has modest activity because of the narrow therapeutic index. Therefore, combination therapy is necessary to increase the anti-tumor effect. Paclitaxel, an anti-mitotic inhibitor, is used as second-line therapy for gastric cancer (GC) as a monotherapy or combination. In this study, we performed RNA sequencing of GC cells treated with iBET-151 and/or paclitaxel to identify the differentially expressed genes associated with possible mechanisms of synergistic effect. We also performed Gene Ontology enrichment and Kyoto Encyclopedia of Genes and Genomes pathway analyses to determine the most enriched terms and pathways of upregulated and downregulated genes. We found 460 genes in which iBET-151 and paclitaxel combination treatment changed more than single-treatment or no-treatment. Thus, additional functional studies are needed, but our results provide the first evidence of the synergistic effect between iBET-151 and paclitaxel in regulating the transcriptome of GC cells.