• 대한한방부인과학회지
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• 제19권4호
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• pp.279-286
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• 2006

Purpose : The purpose of this study is to report the effect of oriental treatments to hyperemesis gravidarum in disturbed liver function. Methods : Hyperemesis gravidarum is a severe and intractable form of nausea and vomiting in pregnancy. It is a diagnosis of exclusion and may result in weight loss; nutritional deficiencies; and abnormalities in fluids, electrolyte levels, and acid-base balance. The peak incidence is at 4, 8-16 weeks of pregnancy. Interestingly, nausea and vomiting of pregnancy is generally associated with a lower rate of miscarriage. However disturbed diver dunction with Hyperemesis gravidarium is rare very and dangerous. Traditionally, oriental medical therapy has been used to patients with hyperemesis gravidarum and showed effective result. We treated 1 patient who had hyperemesis gravidarum in disturbed diver dunction at Se-Myung university Oriental Hospital in affiliation by Herbal medication, acupuncture and moxa therapy and got good result from them. Results : As a result, symptoms are remarkably alleviated and liver function test are improved. Conclusion : Therefore we would like to report that it is effective to cure the hyperemesis gravidarum in disturbed liver function through the herb-medication and acupuncture treatment.

• 한국지반환경공학회 논문집
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• 제13권11호
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• pp.81-91
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• 2012

이 논문은 폐기물 매립지에 사용되는 차수시설로서 토목섬유-흙 시스템의 접촉면에 대한 동적거동을 예측하기 위하여 제안된 교란도함수의 확률적 특성 분석에 대한 내용을 다루고 있다. 우선 다기능 접촉면 전단시험기(M-PIA)에 의한 다수의 시험자료를 활용하여 토목섬유-흙의 접촉면에 대한 교란도함수 모델의 매개변수를 보정하고 그 통계특성을 산정하였다. 다음으로 화학적인자와 상재하중의 영향을 고려한 교란도함수의 확률적 특성분석을 위하여, 산정된 A와 Z의 통계특성과 매우 효율적인 샘플링기법인 LHS기법을 적용함으로써 교란도함수 모델의 확률적 특성인 평균, 변동계수 및 분포형태를 분석하였다. 그 결과로서 ${\xi}_D$의 수준에 따라 교란도함수의 변동성은 약 최소 10%에서 최대 28% 정도로 나타났으며, 분포형태는 대부분의 ${\xi}_D$수준에서 Weibull 분포가 가장 적합한 것으로 나타났다. 이 연구를 통하여 획득한 교란도함수의 확률특성을 활용하면 향후 접촉면 전단강도의 불확실성과 변동성을 정량적으로 명확하게 고려할 수 있는 토목섬유-흙 접촉면의 확률론적 안전성 평가기법의 개발이 가능할 것으로 판단된다.

• Molecules and Cells
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• 제37권6호
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• pp.435-440
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• 2014

Hemodynamic shear stress, the frictional force acting on vascular endothelial cells, is crucial for endothelial homeostasis under normal physiological conditions. When discussing blood flow effects on various forms of endothelial (dys)function, one considers two flow patterns: steady laminar flow and disturbed flow because endothelial cells respond differently to these flow types both in vivo and in vitro. Laminar flow which exerts steady laminar shear stress is atheroprotective while disturbed flow creates an atheroprone environment. Emerging evidence has provided new insights into the cellular mechanisms of flowdependent regulation of vascular function that leads to cardiovascular events such as atherosclerosis, atherothrombosis, and myocardial infarction. In order to study effects of shear stress and different types of flow, various models have been used. In this review, we will summarize our current views on how disturbed flow-mediated signaling pathways are involved in the development of atherosclerosis.

• Structural Engineering and Mechanics
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• 제5권6호
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• pp.803-815
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• 1997

It is well understood that concentrated forces applied in the plane of a beam or panel (such as a wall or slab) lead to splitting forces developing within a disturbed region forming beyond the bearing zone. In a linearly elastic material the length of the disturbed region is approximately equal to the depth of the member. In concrete structures, however, the length of the disturbed region is a function of the orthotropic properties of the concrete-steel composite. In the detailing of steel reinforcement within the disturbed regions two limit states must be satisfied; strength and serviceability (in this case the serviceability requirement being acceptable crack widths). If the design requires large redistribution of stresses, the member may perform poorly at service and/or overload. In this paper the results of a plane stress finite element investigation of concentrated loads on reinforced concrete panels are presented. Two cases are examined (i) panels loaded concentrically, and (ii) panels loaded eccentrically. The numerical investigation suggests that the bursting force distribution is substantially different from that calculated using elastic design methods currently used in some codes of practice. The optimum solution for a uniformly reinforced bursting region was found to be with the reinforcement distributed from approximately 0.2 times the effective depth of the member ($0.2D_e$) to between $1.2D_e$ and $1.6D_e$. Strut and tie models based on the finite element analyses are proposed herein.

• 한국지진공학회:학술대회논문집
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• 한국지진공학회 2003년도 춘계 학술발표회논문집
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• pp.140-147
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• 2003

There are many problems in the prediction of soil dynamic behaviors because undrained excess pore water pressure builds up and then the strain softening behavior is occurred simultaneously. A few analytical methods based on the dynamic constitutive model have been proposed but the model hardly predict the excess pore water pressure directly. In this study, the verification on the disturbed state concept (DSC) model, proposed by Dr, Desai was performed. Some laboratory tests such as conventional triaxial tests and cyclic triaxial tests were carried out to determine DSC Parameters and then disturbance values are determined by the proposed equation. Through this verification, it is proved that the disturbed state concept can express reliably the soil dynamic characteristics such as excess pore water pressure and strain softening behavior. It is also found that the critical disturbance which is determined at the minimum curvature of disturbance function can be a the specific index.

• 한국농공학회지
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• 제36권3호
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• pp.90-99
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• 1994

To investigate the undrained shear strength characteristics of marine soils with high water content, high compressibility and weak bearing capacity, a series of undrained triaxial tests with pore pressure measurements on undisturbed and disturbed Banwol marine clay in normally consolidated and overconsolidated states is carried out. The results and main conclusions of this study are summarized as follows : 1 . When the consolidation pressure is increased, the maximum deviator stress of disturbed and undistubed clay in normally consolidated state is increased. Pore pressure parameters and internal friction angle of undisturbed clay are greater than those of disturbed clay. 2. The relationship between pore pressure and axial strain of undisturbed clay in normally consolidated state can be expressed as a hyperbolic function like stress-strain relation proposed by Kondner. 3. In the pore pressure-axial strain relation of disturbed clay in normally consolidated state, failure ratio R'f is greatly deviated in the range of 0.7~0.9 proposed by Christian and Desai. 4. For overconsolided clay, when overconsolidation ratio (OCR) is increased, normalized maximum deviator stress is increased and maximum pore pressure is decreased gradually. 5. Cohesion of overconsolidated clay is greater than that of nomally consolidated clay and internal friction angle slightly is decreased. 6. Pore pressure parameter at failure (Af) of overconsolidated clay is varied with OCR, Af becomes negative values with increment in OCR

• 한국지반공학회논문집
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• 제19권5호
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• pp.223-232
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• 2003

본 연구에서는 DSC를 이용한 구성방정식을 이용하여 토목섬유 사이의 접촉전단 응력과 변위와의 관계를 모델링하였다. DSC 모델은 두 개의 기준 상태, 즉 상대적으로 손상되지 않은 RI 상태와 완전히 파괴된 FA 상태와 한가지의 교란 함수로 구성된다. 본 모델은 통합된 모델로서, RI 상태를 탄성-완전 소성 모델, 계층적 단일 항복곡면 (HiSS) 모델 등 다양한 모델을 이용하여 모사할 수 있다. 한편 본 모델은 탄성과 소성 변위를 동시에 고려할 수 있다는 장점을 가지고 있다. 4가지의 대형 직접전단 시험으로부터 측정된 자료와 측정자료로부터 도출된 모델 변수를 이용하여 재해석한 결과를 서로 비교하여, 둘 사이의 비교 결과가 상당히 일치함을 발견하였으며, 특히 표면이 매끄러운 지오멤브레인의 접촉면에서는 매우 상관관계를 보였다. 비록 표면이 거친 지오멤브레인이 포함된 접촉면에서는 예측 최대 전단강도가 실험결과와 약간의 차이를 보이기는 하였지만, 전체적으로 본 모델이 최대 전단응력이 나타나는 변위점과 대변형에서의 전단강도를 상당히 정확히 예측하였으며, 이를 통해 본 모델이 변형율 연화 현상을 보이는 접촉면 전단거동의 모델링에 유용함을 확인하였다.

• 한국지반환경공학회 논문집
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• 제11권11호
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• pp.47-54
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• 2010

최근 쓰레기 매립장에 보강 및 보호 목적으로 토목섬유가 널리 사용되고 있다. 최근 연구결과, 토목섬유-흙 접촉면에서는 진행성 파괴가 발생할 수 있는데 이는 토목섬유-흙 접촉면에서 함수비, 연직응력, 화학적 요소의 영향 등 고유물성에 기인한다. 본 연구에서는 침출수 내의 산성 및 염기성과 같은 성분의 영향이 진동하중 상태에서 토목섬유-흙 접촉면의 전단강도 감소에 미치는 영향을 실내 시험을 통하여 분석하였다. 다기능 접촉면 시험기를 새로 구축하고 서로 다른 pH 조건에서 수침시킨 토목섬유와 흙시료를 이용하여 진동 직접전단시험을 수행하여 접촉면 전단두께와 화학적 요소에 의한 접촉면의 전단강도 감소를 확인하였다. 또한 접촉면 전단강도 감소를 정량적으로 표현하기 위하여 교란상태개념에 기초하여 동하중 하의 화학적 인자들에 의한 토목섬유-흙 접촉면의 정규화 교란도 함수를 파악하고 전단강도 감소 특성을 확인하였다.

• 동의생리병리학회지
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• 제24권6호
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• pp.903-906
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• 2010

The spleen is the source of gi, blood, body fluid and plays a vital role in maintaining life. The function of the spleen is to transform food nutrients and water, and to transport them to the heart and the lung. The movement of splenic gi is marked by elevation. The spleen governs the activity of elevating the lucid. The function of transportation and transformation is usually disturbed in the state of Gi deficiency of the spleen. The main clinical manifestations of gi deficiency of the spleen can be divided into as followers: anorexia, loose stool if the digesting and absorbing functions are disturbed; phlegm and edema if dampness and water are retained due to unhealthy water metabolism. Sagunja-tang can be applied for gi deficiency syndrome of the spleen. Ingredient bakchul(Rhizoma Atractylodis Macrocephalae) and bokryeung(Poria) can be used as monarch drug to eliminate dampness and strengthen the spleen.

• Environmental Analysis Health and Toxicology
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• 제18권1호
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• pp.33-44
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• 2003

The possibility that liver and kidney function is adversely affected by current levels of environmental exposure to cadmium (Cd) as investigated in adult men and women in the general population in Seoul. From February to August in 2001, blood and morning spot urine samples were collected from 136 not occupationally exposed group (age range 20∼75 years) at 4 survey sites throughout seoul. Liver and kidney function parameters in serum and urine were examined by conventional methods. The questionnaire included factors, i.e. sex, age, smoking, alcohol, diet habit etc. The geometric mean values for Cd in blood (Cd-B) were 1.43 $\mu\textrm{g}$/1, It seemed prudent to conclude that liver and kidney function as not disturbed by the current environmental exposure to Cd in study.