1 |
Le, N.T., Heo, K.S., Takei, Y., Lee, H., Woo, C.H., Chang, E., McClain, C., Hurley, C., Wang, X., Li, F., et al. (2013). A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis. Circulation 127, 486-499.
DOI
ScienceOn
|
2 |
Liu, Y., Chen, B.P., Lu, M., Zhu, Y., Stemerman, M.B., Chien, S., and Shyy, J.Y. (2002). Shear stress activation of SREBP1 in endothelial cells is mediated by integrins. Arterioscler. Thromb. Vasc. Biol. 22, 76-81.
DOI
ScienceOn
|
3 |
Michiels, C. (2003). Endothelial cell functions. J. Cell. Physiol. 196, 430-443.
DOI
ScienceOn
|
4 |
Nam, D., Ni, C.W., Rezvan, A., Suo, J., Budzyn, K., Llanos, A., Harrison, D., Giddens, D., and Jo, H. (2009). Partial carotid ligation is a model of acutely induced disturbed flow, leading to rapid endothelial dysfunction and atherosclerosis. Am. J. Physiol. Heart Circ. Physiol. 297, H1535-1543.
DOI
ScienceOn
|
5 |
Nauli, S.M., Jin, X., AbouAlaiwi, W.A., El-Jouni, W., Su, X., and Zhou, J. (2013). Non-motile primary cilia as fluid shear stress mechanosensors. Methods Enzymol. 525, 1-20.
DOI
|
6 |
Heo, K.S., Chang, E., Le, N.T., Cushman, H.J., Yeh, E.T.H., Fujiwara, K., and Abe, J.I. (2013). De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis. Circ. Res. 112, 911-923.
DOI
ScienceOn
|
7 |
Iiyama, K., Hajra, L., Iiyama, M., Li, H., DiChiara, M., Medoff, B.D., and Cybulsky, M.I. (1999). Patterns of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit and mouse atherosclerotic lesions and at sites predisposed to lesion formation. Circ. Res. 85, 199-207.
DOI
ScienceOn
|
8 |
Jalali, S., del Pozo, M.A., Chen, K., Miao, H., Li, Y., Schwartz, M.A., Shyy, J.Y., and Chien, S. (2001). Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands. Proc. Natl. Acad. Sci. USA 98, 1042-1046.
DOI
ScienceOn
|
9 |
Jongstra-Bilen, J., Haidari, M., Zhu, S.N., Chen, M., Guha, D., and Cybulsky, M.I. (2006). Low-grade chronic inflammation in regions of the normal mouse arterial intima predisposed to atherosclerosis. J. Exp. Med. 203, 2073-2083.
DOI
ScienceOn
|
10 |
Johnson, B.D., Mather, K.J., and Wallace, J.P. (2011). Mechanotransduction of shear in the endothelium: basic studies and clinical implications. Vasc. Med. 16, 365-377.
DOI
ScienceOn
|
11 |
Kano, Y., Katoh, K., and Fujiwara, K. (2000). Lateral zone of cell-cell adhesion as the major fluid shear stress-related signal transduction site. Circ. Res. 86, 425-433.
DOI
ScienceOn
|
12 |
Koskinas, K.C., Chatzizisis, Y.S., Antoniadis, A.P., and Giannoglou, G.D. (2012). Role of endothelial shear stress in stent restenosis and thrombosis: pathophysiologic mechanisms and implications for clinical translation. J. Am. Coll. Cardiol. 59, 1337-1349.
DOI
ScienceOn
|
13 |
Goel, R., Schrank, B.R., Arora, S., Boylan, B., Fleming, B., Miura, H., Newman, P.J., Molthen, R.C., and Newman, D.K. (2008). Site-specific effects of PECAM-1 on atherosclerosis in LDL receptor-deficient mice. Arterioscler. Thromb. Vasc. Biol. 28, 1996-2002.
DOI
ScienceOn
|
14 |
Gudi, S., Huvar, I., White, C.R., McKnight, N.L., Dusserre, N., Boss, G.R., and Frangos, J.A. (2003). Rapid activation of Ras by fluid flow is mediated by Galpha(q) and Gbetagamma subunits of heterotrimeric G proteins in human endothelial cells. Arterioscler. Thromb. Vasc. Biol. 23, 994-1000.
DOI
ScienceOn
|
15 |
Hajra, L., Evans, A.I., Chen, M., Hyduk, S.J., Collins, T., and Cybulsky, M.I. (2000). The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation. Proc. Natl. Acad. Sci. USA 97, 9052-9057.
DOI
|
16 |
Heo, K.S., Lee, H., Nigro, P., Thomas, T., Le, N.T., Chang, E., McClain, C., Reinhart-King, C.A., King, M.R., Berk, B.C., et al. (2011b). PKCzeta mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation. J. Cell Biol. 193, 867-884.
DOI
ScienceOn
|
17 |
Harry, B.L., Sanders, J.M., Feaver, R.E., Lansey, M., Deem, T.L., Zarbock, A., Bruce, A.C., Pryor, A.W., Gelfand, B.D., Blackman, B.R., et al. (2008). Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice. Arterioscler. Thromb. Vasc. Biol. 28, 2003-2008.
DOI
ScienceOn
|
18 |
Helmke, B.P., Goldman, R.D., and Davies, P.F. (2000). Rapid displacement of vimentin intermediate filaments in living endothelial cells exposed to flow. Circ. Res. 86, 745-752.
DOI
ScienceOn
|
19 |
Heo, K.S., Fujiwara, K., and Abe, J. (2011a). Disturbed-flow-mediated vascular reactive oxygen species induce endothelial dysfunction. Circ. J. 75, 2722-2730.
DOI
ScienceOn
|
20 |
Curry, F.E., and Adamson, R.H. (2012). Endothelial glycocalyx: permeability barrier and mechanosensor. Ann. Biomed. Eng. 40, 828-839.
DOI
|
21 |
Davies, P.F. (2009). Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology. Nat. Clin. Pract. Cardiovasc. Med. 6, 16-26.
DOI
ScienceOn
|
22 |
Davies, M.J., Gordon, J.L., Gearing, A.J., Pigott, R., Woolf, N., Katz, D., and Kyriakopoulos, A. (1993). The expression of the adhesion molecules ICAM-1, VCAM-1, PECAM, and E- selectin in human atherosclerosis. J. Pathol. 171, 223-229.
DOI
ScienceOn
|
23 |
Davis, M.E., Cai, H., Drummond, G.R., and Harrison, D.G. (2000). Regulation of endothelial nitric oxide synthase (eNOS) expression by laminar shear stress (abstract). Circulation 102, II-117.
|
24 |
Garin, G., Abe, J.I., Mohan, A., Lu, W., Yan, C., Newby, A.C., Rhaman, A., and Berk, B.C. (2007). Flow antagonizes TNF-alpha signaling in endothelial cells by inhibiting caspase-dependent PKC zeta processing. Circ. Res. 101, 97-105.
DOI
ScienceOn
|
25 |
Davis, M.E., Cai, H., Drummond, G.R., and Harrison, D.G. (2001). Shear stress regulates endothelial nitric oxide synthase expression through c-Src by divergent signaling pathways. Circ. Res. 89, 1073-1080.
DOI
ScienceOn
|
26 |
Dixit, M., Loot, A.E., Mohamed, A., Fisslthaler, B., Boulanger, C.M., Ceacareanu, B., Hassid, A., Busse, R., and Fleming, I. (2005). Gab1, SHP2, and protein kinase A are crucial for the activation of the endothelial NO synthase by fluid shear stress. Circ. Res. 97, 1236-1244.
DOI
ScienceOn
|
27 |
Fleming, I., Fisslthaler, B., Dixit, M., and Busse, R. (2005). Role of PECAM-1 in the shear-stress-induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cells. J. Cell Sci. 118, 4103-4111.
DOI
ScienceOn
|
28 |
Geiss-Friedlander, R., and Melchior, F. (2007). Concepts in sumoylation: a decade on. Nat. Rev. Mol. Cell. Biol. 8, 947-956.
DOI
ScienceOn
|
29 |
Barton, M., Baretella, O., and Meyer, M.R. (2012). Obesity and risk of vascular disease: importance of endothelium-dependent vasoconstriction. Br. J. Pharmacol. 165, 591-602.
DOI
ScienceOn
|
30 |
Berk, B.C., Min, W., Yan, C., Surapisitchat, J., Liu, Y., and Hoefen, R. (2002). Atheroprotective mechanisms activated by fluid shear stress in endothelial cells. Drug News Perspect. 15, 133-139.
DOI
ScienceOn
|
31 |
Boo, Y.C., Hwang, J., Sykes, M., Michell, B.J., Kemp, B.E., Lum, H., and Jo, H. (2002). Shear stress stimulates phosphorylation of eNOS at Ser(635) by a protein kinase A-dependent mechanism. Am. J. Physiol. Heart Circ. Physiol. 283, H1819-1828.
DOI
ScienceOn
|
32 |
Chiu, Y.J., McBeath, E., and Fujiwara, K. (2008b). Mechanotransduction in an extracted cell model: Fyn drives stretch- and flow-elicited PECAM-1 phosphorylation. J. Cell Biol. 182, 753-763.
DOI
ScienceOn
|
33 |
Cheng, J., Wang, D., Wang, Z., and Yeh, E.T. (2004). SENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase 1. Mol. Cell. Biol. 24, 6021-6028.
DOI
ScienceOn
|
34 |
Chiu, Y.J., Kusano, K., Thomas, T.N., and Fujiwara, K. (2004). Endothelial cell-cell adhesion and mechanosignal transduction. Endothelium 11, 59-73.
DOI
ScienceOn
|
35 |
Chiu, S.Y., Asai, N., Costantini, F., and Hsu, W. (2008a). SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages. PLoS Biol. 6, e310.
DOI
ScienceOn
|
36 |
Conway, D., and Schwartz, M.A. (2012). Lessons from the endothelial junctional mechanosensory complex. F1000 Biol. Rep. 4, 1.
|
37 |
Akaike, M., Che, W., Marmarosh, N.L., Ohta, S., Osawa, M., Ding, B., Berk, B.C., Yan, C., and Abe, J. (2004). The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma1 (PPARgamma1) mediates interaction with extracellular signalregulated kinase 5 and PPARgamma1 transcriptional activation: involvement in flow-induced PPARgamma activation in endothelial cells. Mol. Cell. Biol. 24, 8691-8704.
DOI
ScienceOn
|
38 |
Ando, J., and Yamamoto, K. (2009). Vascular mechanobiology: endothelial cell responses to fluid shear stress. Circ. J. 73, 1983-1992.
DOI
ScienceOn
|
39 |
Barakat, A.I. (1999). Responsiveness of vascular endothelium to shear stress: potential role of ion channels and cellular cytoskeleton (review). Int. J. Mol. Med. 4, 323-332.
|
40 |
Yu, J., Bergaya, S., Murata, T., Alp, I.F., Bauer, M.P., Lin, M.I., Drab, M., Kurzchalia, T.V., Stan, R.V., and Sessa, W.C. (2006). Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vessels. J. Clin. Invest. 116, 1284-1291.
DOI
|
41 |
Witty, J., Aguilar-Martinez, E., and Sharrocks, A.D. (2010). SENP1 participates in the dynamic regulation of Elk-1 SUMOylation. Biochem. J. 428, 247-254.
DOI
ScienceOn
|
42 |
Won, D., Zhu, S.N., Chen, M., Teichert, A.M., Fish, J.E., Matouk, C.C., Bonert, M., Ojha, M., Marsden, P.A., and Cybulsky, M.I. (2007). Relative reduction of endothelial nitric-oxide synthase expression and transcription in atherosclerosis-prone regions of the mouse aorta and in an in vitro model of disturbed flow. Am. J. Pathol. 171, 1691-1704.
DOI
ScienceOn
|
43 |
Woo, C.H., Massett, M.P., Shishido, T., Itoh, S., Ding, B., McClain, C., Che, W., Vulapalli, S.R., Yan, C., and Abe, J. (2006). ERK5 activation inhibits inflammatory responses via peroxisome proliferator-activated receptor delta (PPARdelta) stimulation. J. Biol. Chem. 281, 32164-32174.
DOI
ScienceOn
|
44 |
Woo, C.H., Shishido, T., McClain, C., Lim, J.H., Li, J.D., Yang, J., Yan, C., and Abe, J. (2008a). Extracellular signal-regulated kinase 5 SUMOylation antagonizes shear stress-induced anti-inflammatory response and endothelial nitric oxide synthase expression in endothelial cells. Circ. Res. 102, 538-545.
DOI
ScienceOn
|
45 |
Woo, C.H., Shishido, T., McClain, C., Lim, J.H., Li, J.D., Yang, J., Yan, C., and Abe, J. (2008b). Extracellular signal-regulated kinase 5 SUMOylation antagonizes shear stress-induced anti-inflammatory response and endothelial nitric oxide synthase expression in endothelial cells. Circ. Res. 102, 538-545.
DOI
ScienceOn
|
46 |
Yeh, E.T. (2009). SUMOylation and De-SUMOylation: wrestling with life's processes. J. Biol. Chem. 284, 8223-8227.
DOI
ScienceOn
|
47 |
Reinhart-King, C.A., Fujiwara, K., and Berk, B.C. (2008). Physiologic stress-mediated signaling in the endothelium. Methods Enzymol. 443, 25-44.
DOI
ScienceOn
|
48 |
Osawa, M., Masuda, M., Harada, N., Bruno Lopes, R., and Fujiwara, K. (1997). Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) in mechanically stimulated vascular endothelial cells. Eur. J. Cell Biol. 72, 229-237.
|
49 |
Osborn, E.A., Rabodzey, A., Dewey, C.F., Jr., and Hartwig, J.H. (2006). Endothelial actin cytoskeleton remodeling during mechanostimulation with fluid shear stress. Am. J. Physiol. Cell Physiol. 290, C444-452.
DOI
|
50 |
Pi, X., Yan, C., and Berk, B.C. (2004). Big mitogen-activated protein kinase (BMK1)/ERK5 protects endothelial cells from apoptosis. Circ. Res. 94, 362-369.
DOI
ScienceOn
|
51 |
Shyy, J.Y., and Chien, S. (2002). Role of integrins in endothelial mechanosensing of shear stress. Circ. Res. 91, 769-775.
DOI
|
52 |
Stern, D.M., Esposito, C., Gerlach, H., Gerlach, M., Ryan, J., Handley, D., and Nawroth, P. (1991). Endothelium and regulation of coagulation. Diabetes Care 14, 160-166.
DOI
ScienceOn
|
53 |
Traub, O., and Berk, B.C. (1998). Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force. Arterioscler. Thromb. Vasc. Biol. 18, 677-685.
DOI
ScienceOn
|
54 |
Tzima, E., del Pozo, M.A., Shattil, S.J., Chien, S., and Schwartz, M.A. (2001). Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment. EMBO J. 20, 4639-4647.
DOI
ScienceOn
|
55 |
Tzima, E., Irani-Tehrani, M., Kiosses, W.B., Dejana, E., Schultz, D.A., Engelhardt, B., Cao, G., DeLisser, H., and Schwartz, M.A. (2005). A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature 437, 426-431.
DOI
ScienceOn
|
56 |
Jiang, M., Chiu, S.Y., and Hsu, W. (2011). SUMO-specific protease 2 in Mdm2-mediated regulation of p53. Cell Death Differ. 18, 1005-1015.
DOI
ScienceOn
|
57 |
Chang, E., Heo, K.S., Woo, C.H., Lee, H., Le, N.T., Thomas, T.N., Fujiwara, K., and Abe, J. (2011). MK2 SUMOylation regulates actin filament remodeling and subsequent migration in endothelial cells by inhibiting MK2 kinase and HSP27 phosphorylation. Blood 117, 2527-2537.
DOI
ScienceOn
|
58 |
Young, A., Wu, W., Sun, W., Benjamin Larman, H., Wang, N., Li, Y.S., Shyy, J.Y., Chien, S., and Garcia-Cardena, G. (2009). Flow activation of AMP-activated protein kinase in vascular endothelium leads to Kruppel-like factor 2 expression. Arterioscler. Thromb. Vasc. Biol. 29, 1902-1908.
DOI
ScienceOn
|