• The Journal of Korean Obstetrics and Gynecology
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• v.19 no.4
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• pp.279-286
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• 2006

Purpose : The purpose of this study is to report the effect of oriental treatments to hyperemesis gravidarum in disturbed liver function. Methods : Hyperemesis gravidarum is a severe and intractable form of nausea and vomiting in pregnancy. It is a diagnosis of exclusion and may result in weight loss; nutritional deficiencies; and abnormalities in fluids, electrolyte levels, and acid-base balance. The peak incidence is at 4, 8-16 weeks of pregnancy. Interestingly, nausea and vomiting of pregnancy is generally associated with a lower rate of miscarriage. However disturbed diver dunction with Hyperemesis gravidarium is rare very and dangerous. Traditionally, oriental medical therapy has been used to patients with hyperemesis gravidarum and showed effective result. We treated 1 patient who had hyperemesis gravidarum in disturbed diver dunction at Se-Myung university Oriental Hospital in affiliation by Herbal medication, acupuncture and moxa therapy and got good result from them. Results : As a result, symptoms are remarkably alleviated and liver function test are improved. Conclusion : Therefore we would like to report that it is effective to cure the hyperemesis gravidarum in disturbed liver function through the herb-medication and acupuncture treatment.

• Journal of the Korean GEO-environmental Society
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• v.13 no.11
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• pp.81-91
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• 2012

This paper mainly deals with the analysis of probabilistic characteristics of the disturbed function proposed to predict dynamic behavior of Geosynthetic-soil interface as the lining and cover systems used in waste landfills. Calibration and statistical property estimation of the parameters in the disturbed function model were first performed using many experimental data obtained from a new multi-purpose interface apparatus (M-PIA). In order to analyze the effect due to changes in chemical degradation and normal loads condition, probabilistic properties such as mean, coefficient of variation and distribution type of the disturbed function were evaluated using both the LHS method known to be a very efficient sampling scheme and the estimated statistical property of A and Z. As a result, variation of the disturbed function is found to range approximately from 10~28% according to the level of ${\xi}_D$ and Weibull appears to be the most adequate distribution type at almost all levels of ${\xi}_D$. It is concluded that a probabilistic safety assessment method for Geosynthetic-soil interface considering uncertainty in shear strength can be developed by utilizing probabilistic properties of the disturbed function obtained in this study.

• Molecules and Cells
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• v.37 no.6
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• pp.435-440
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• 2014

Hemodynamic shear stress, the frictional force acting on vascular endothelial cells, is crucial for endothelial homeostasis under normal physiological conditions. When discussing blood flow effects on various forms of endothelial (dys)function, one considers two flow patterns: steady laminar flow and disturbed flow because endothelial cells respond differently to these flow types both in vivo and in vitro. Laminar flow which exerts steady laminar shear stress is atheroprotective while disturbed flow creates an atheroprone environment. Emerging evidence has provided new insights into the cellular mechanisms of flowdependent regulation of vascular function that leads to cardiovascular events such as atherosclerosis, atherothrombosis, and myocardial infarction. In order to study effects of shear stress and different types of flow, various models have been used. In this review, we will summarize our current views on how disturbed flow-mediated signaling pathways are involved in the development of atherosclerosis.

• Structural Engineering and Mechanics
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• v.5 no.6
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• pp.803-815
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• 1997

It is well understood that concentrated forces applied in the plane of a beam or panel (such as a wall or slab) lead to splitting forces developing within a disturbed region forming beyond the bearing zone. In a linearly elastic material the length of the disturbed region is approximately equal to the depth of the member. In concrete structures, however, the length of the disturbed region is a function of the orthotropic properties of the concrete-steel composite. In the detailing of steel reinforcement within the disturbed regions two limit states must be satisfied; strength and serviceability (in this case the serviceability requirement being acceptable crack widths). If the design requires large redistribution of stresses, the member may perform poorly at service and/or overload. In this paper the results of a plane stress finite element investigation of concentrated loads on reinforced concrete panels are presented. Two cases are examined (i) panels loaded concentrically, and (ii) panels loaded eccentrically. The numerical investigation suggests that the bursting force distribution is substantially different from that calculated using elastic design methods currently used in some codes of practice. The optimum solution for a uniformly reinforced bursting region was found to be with the reinforcement distributed from approximately 0.2 times the effective depth of the member ($0.2D_e$) to between $1.2D_e$ and $1.6D_e$. Strut and tie models based on the finite element analyses are proposed herein.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2003.03a
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• pp.140-147
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• 2003

There are many problems in the prediction of soil dynamic behaviors because undrained excess pore water pressure builds up and then the strain softening behavior is occurred simultaneously. A few analytical methods based on the dynamic constitutive model have been proposed but the model hardly predict the excess pore water pressure directly. In this study, the verification on the disturbed state concept (DSC) model, proposed by Dr, Desai was performed. Some laboratory tests such as conventional triaxial tests and cyclic triaxial tests were carried out to determine DSC Parameters and then disturbance values are determined by the proposed equation. Through this verification, it is proved that the disturbed state concept can express reliably the soil dynamic characteristics such as excess pore water pressure and strain softening behavior. It is also found that the critical disturbance which is determined at the minimum curvature of disturbance function can be a the specific index.

• Magazine of the Korean Society of Agricultural Engineers
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• v.36 no.3
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• pp.90-99
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• 1994

To investigate the undrained shear strength characteristics of marine soils with high water content, high compressibility and weak bearing capacity, a series of undrained triaxial tests with pore pressure measurements on undisturbed and disturbed Banwol marine clay in normally consolidated and overconsolidated states is carried out. The results and main conclusions of this study are summarized as follows : 1 . When the consolidation pressure is increased, the maximum deviator stress of disturbed and undistubed clay in normally consolidated state is increased. Pore pressure parameters and internal friction angle of undisturbed clay are greater than those of disturbed clay. 2. The relationship between pore pressure and axial strain of undisturbed clay in normally consolidated state can be expressed as a hyperbolic function like stress-strain relation proposed by Kondner. 3. In the pore pressure-axial strain relation of disturbed clay in normally consolidated state, failure ratio R'f is greatly deviated in the range of 0.7~0.9 proposed by Christian and Desai. 4. For overconsolided clay, when overconsolidation ratio (OCR) is increased, normalized maximum deviator stress is increased and maximum pore pressure is decreased gradually. 5. Cohesion of overconsolidated clay is greater than that of nomally consolidated clay and internal friction angle slightly is decreased. 6. Pore pressure parameter at failure (Af) of overconsolidated clay is varied with OCR, Af becomes negative values with increment in OCR

• Journal of the Korean Geotechnical Society
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• v.19 no.5
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• pp.223-232
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• 2003

In this study, a constitutive model called the disturbed state concept (DSC) was modified to be applied to the interface shear stress-displacement relationship between geosynthetics. The DSC model is comprised of two reference states, namely the relative intact (RI) and the fully adjusted (FA) state, and one function, namely the disturbance function. This model is a unified approach and can allow for various models as an RI state such as elastic-perfectly plastic model, hierarchical model, and so on. In addition, by using this model, the elastic and plastic displacements can be considered simultaneously. Comparisons between the measured data and predicted results through the parameters determined from four sets of large direct shear tests showed good agreements with each other, especially for the smooth geomembrane-involved interface. Although there are slight differences at peak shear strength for textured geomembrane-involved interface, this model can still be useful to predict the position of displacement at peak strength and the large displacement (or residual) shear strength.

• Journal of the Korean GEO-environmental Society
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• v.11 no.11
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• pp.47-54
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• 2010

Nowadays, geosynthetics for reinforcement and protection are widely applied to the waste landfill site. Current research indicates the potential for progressive failure in geosynthetic-soil system depends on the interface shear strength governed by several intrinsic factors such as moisture, normal stress, chemical, etc. In particular, the effect of the acidity and basicity from the leachate is intensively reviewed to assess the chemical reaction mechanism of interface shear strength under the cyclic loading condition. New multi-purpose interface apparatus(M-PIA) has been manufactured and the cyclic direct shear tests using submerged geosynthetics and soils under the different chemical conditions have been performed, consequently, the thickness of interface and shear stress degradation are verified. The basic schematic of the Disturbed State Concept(DSC) is employed to estimate the shear stress degradation in the interface, then, normalized disturbed function is obtained and analyzed to describe the shear stress degradation of geosynthetic-soil interface with chemical influence factors under dynamic condition.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.6
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• pp.903-906
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• 2010

The spleen is the source of gi, blood, body fluid and plays a vital role in maintaining life. The function of the spleen is to transform food nutrients and water, and to transport them to the heart and the lung. The movement of splenic gi is marked by elevation. The spleen governs the activity of elevating the lucid. The function of transportation and transformation is usually disturbed in the state of Gi deficiency of the spleen. The main clinical manifestations of gi deficiency of the spleen can be divided into as followers: anorexia, loose stool if the digesting and absorbing functions are disturbed; phlegm and edema if dampness and water are retained due to unhealthy water metabolism. Sagunja-tang can be applied for gi deficiency syndrome of the spleen. Ingredient bakchul(Rhizoma Atractylodis Macrocephalae) and bokryeung(Poria) can be used as monarch drug to eliminate dampness and strengthen the spleen.

• Environmental Analysis Health and Toxicology
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• v.18 no.1
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• pp.33-44
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• 2003

The possibility that liver and kidney function is adversely affected by current levels of environmental exposure to cadmium (Cd) as investigated in adult men and women in the general population in Seoul. From February to August in 2001, blood and morning spot urine samples were collected from 136 not occupationally exposed group (age range 20∼75 years) at 4 survey sites throughout seoul. Liver and kidney function parameters in serum and urine were examined by conventional methods. The questionnaire included factors, i.e. sex, age, smoking, alcohol, diet habit etc. The geometric mean values for Cd in blood (Cd-B) were 1.43 $\mu\textrm{g}$/1, It seemed prudent to conclude that liver and kidney function as not disturbed by the current environmental exposure to Cd in study.