• Journal of Pharmaceutical Investigation
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• v.35 no.1
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• pp.1-5
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• 2005

ABSTRACT -Ipriflavone is a synthetic flavonoid derivate that improves osteoblast cell activity inhibiting bone resorption. In order to improve the bioavailability, solid dispersions of ipriflavone with PVP (poly-N-vinylpyrrolidone, MW=40,000 g/mole) were prepared by a spray-drying method. During the manufacturing of solid dispersion, various solvents [ethanol (EtOH), acetonitrile, methylene chloride and cosolvent-EtOH:acetone=1:1] were used to dissolve the ipriflavone and PVP. Scanning electron microscopy (SEM) and differential scanning calorimetry (DSC) were used to evaluate the physicochemical interaction between ipriflavone and PVP. Particle size, crystallinity and the area of the endotherm $({\Delta}H)$ of solid dispersed ipriflavone using the acetonitrile as solvent were much smaller than those of the other preparation types. Bioavailability of ipriflavone in vivo was changed by solvents. When considering the result of in vivo test, solid dispersion of ipriflavone using the acetonitrile as solvent showed the best choice.

• Korean journal of applied entomology
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• v.40 no.2
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• pp.105-109
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• 2001

Dispersion pattern of the citrus red mite (CRM), Panonychus citri (McGregor) was determined to develop a monitoring method in the satsuma mandarin fields, Citrus unshiu L., in Jeju-do, during 1999 and 2000. CRM population was sampled by collecting leaves. Taylor's power law provided better description of mean-variance relationship for the dispersion indices compared to Iwao's patchiness regression. Slopes and intercepts of Taylor's power law from leaf samples did not differ among surveyed groves. Fixed-precision levels (D) of a sequential sampling plan were developed using Taylor's power law parameters generated from all motile stages of CRM in leaf sample. This sampling plan for leaf sample estimate was tested with resampling validation for sampling plan using 4 independent data sets. Resampling simulation analysis demonstrated that actual fixed-precision level values were better than desired D values of 0.20, 0.25 and 0.30. Required numbers for tree sampling at the density of more than 7 mites per tree were fewer than 18.

• Macromolecular Research
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• v.16 no.1
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• pp.6-14
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• 2008

Polypropylene (PP)-layered silicate nanocomposites were developed using a new processing method involving a supercritical carbon dioxide ($scCO_2$)-assisted co-rotating twin-screw extrusion process. The nanocomposites were prepared through two step extrusion processes. In the first step, the PP/clay mixture was extruded with $CO_2$ injected into the barrel of the extruder and the resulting foamed extrudate was cooled and pelletized. In the second step, the foamed extrudate was extruded with venting to produce the final PP/clay nanocomposites without $CO_2$. In this study, organophilic-clay and polypropylene matrix were used. Maleic anhydride grafted polypropylene (PP-g-MA) was used as a compatibilizer. This study focused on the effect of $scCO_2$ on the dispersion characteristics of the clays into a PP matrix and the rheological properties of the layered silicate based PP nanocomposites. The dispersion properties of clays in the nanocomposites as well as the rheological properties of the nanocomposites were examined as a function of the PP-g-MA concentration. The degree of dispersion of the clays in the nanocomposites was analyzed by X-ray diffraction and transmission electron microscope. Various rheological properties of the nanocomposites were measured using a rotational rheometer. In the experimental results, the $scCO_2$ assisted continuous manufacturing extrusion system was used to successfully produce the organophilic-clay filled PP nanocomposites. It was found that $scCO_2$ had a measurable effect on the clay dispersion in the polymer matrix and the melt intercalation of a polymer into clay layers.

• The Korean Journal of Applied Statistics
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• v.30 no.4
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• pp.529-538
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• 2017

The Ghosh and Kim zero-altered distribution model is used to analyze count data that have too many or too few zeros. The dispersion type parameter ${\delta}$ in the zero-altered distribution model consists of mean, variance and zero probability and has two forms depending on the relation between ${\mu}$ and ${\sigma}^2$. We derived the influence function on ${\delta}$ when ${\sigma}^2{\geq}{\mu}$. To show the validity of the influence function, we used the Census data on the number of births of married women in Korea to compare the estimated changes in ${\delta}$ using this function with those obtained using the direct deletion method. The result proved that the obtained influence function is very accurate in estimating changes in ${\delta}$ when an observation is deleted.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.41 no.8
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• pp.51-57
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• 2004

We have analyzed the effect of out-band dispersion in the cascaded fiber Bragg Elating(FBG) based optical add-drop multiplexers(OADM) when bypassed wavelengths contain SCM signals. In order to compute this impairment the dispersion characteristics of FBG have been analytically calculated by solving their coupled wave equations, and the Fourier method is applied to IMD analysis. The out-band dispersion effects over WDM/SCM signals are analyzed under different and common system situations as: ITU channel spacing(100, 50, 25 GHz), channel density parameter, frequency extension of the SCM plan, modulation characteristics, FBG length, etc. From this results, the transport of WDM/SCM signals in future DWDM transport networks could be limited by this effect which has to be taken into account for designing future networks.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.21 no.9
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• pp.835-843
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• 2008

We have fabricated the source-drain electrodes for OTFTs by screen printing method and manufactured Ag pastes as conductive paste. To obtain excellent conductivity and screen-printability of Ag pastes, the dispersion characteristics of Ag pastes prepared from two types of acryl resins with different molecular structures and Ag powder treated with caprylic acid, triethanol amine and dodecane thiol as surfactant respectively were investigated. The Ag pastes containing Ag powder treated with dodecane thiol having thiol as anchor group or AA4123 with carboxyl group(COOH) of hydrophilic group as binder resin exhibited excellent dispersity. But, Ag pastes(CA-41, TA-41, DT-41) prepared from AA4123 fabricated the insulating layer since the strong interaction between surface of Ag powder and carboxyl group(COOH) of AA4123 interfered with the formation of conduction path among Ag powders. The viscosity behavior of Ag pastes exhibited shear-thinning flow in the high shear rate range and the pastes with bad dispersion characteristic demonstrated higher shear-thinning index than those with good dispersity due to the weak flocculated network structure. The output curve of OTFT device with a channel length of 107 ${\mu}m$ using screen-printed S-D electrodes from DT-30 showed good saturation behavior and no significant contact resistance. And this device exhibited a saturation mobility of $4.0{\times}10^{-3}$ $cm^2/Vs$, on/off current ratio of about $10^5$ and a threshold voltage of about 0.7 V.

• Polymer(Korea)
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• v.32 no.6
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• pp.549-554
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• 2008

In order to synthesize polymer particle containing inorganic material, styrene and n-butylmethacrylate were copolymerized with alumina by dispersion polymerization. The weight ratio of styrene to n-butylmethacrylate was 3 : 1. A poly(N-vinyl pyrrolidon) was added as stabilizer. 2,2'-AzobisCisobutyronitrile) and 3-methacryloxypropyl trimethoxysilane were used as initiator and coupling agent, respectively. The weight ratio of 70 : 30 of isopropanol to distilled water was used as dispersion medium. According to the TEM measurement, we could confirm that alumina was dispersed into the polymer particle. The increase 'of concentration of alumina resulted in enhancement of particle size, but decreased its distribution. By the XRD method, it was found that the increase of alumina concentration showed the increase of intensity in peak and the increased 2$\theta$ value. From the TGA measurement, the increase of alumina concentration caused high heat resistance of the polymer. With respect to the type of initiator, the longer half life of initiator, the smaller particle size. We also found that the increase of particle stabilizer concentration made the decreased of particle size due to the accelerated generation of polymer particle in the early stage of reaction.

• Journal of the Korean Society for Nondestructive Testing
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• v.26 no.4
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• pp.239-245
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• 2006

Experimentally measured Lamb wave group velocities in composite materials with anisotropic characteristics are not accorded with the theoretical group velocities as calculated with the Lamb wave dispersion equation. This discrepancy arises from the fact that the angle between the group velocity direction and the phase velocity direction in anisotropic materials exists. Wave propagation in a composite material with anisotropic characteristics should be considered with respect to magnitude in addition to direction. In this study, $S_0$ mode phase velocity dispersion corves are depicted with the variation of degree with respect to the fiber direction using a Lamb wave dispersion relation in the unidirectional, bidirectional, and quasi-isotropic composite plates. Slowness surface is sketched by the reciprocal value of the phase velocity curves. The magnitude and direction of the group velocity are calculated from the slowness surface. The theoretically determined group velocity, which is calculated from the slowness surface, Is compared with experimentally measured group velocities. The proposed method shows good agreements with theoretical and experimental results.

• Journal of The Korean Society of Agricultural Engineers
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• v.61 no.6
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• pp.21-30
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• 2019

Livestock odor is comprised of mixed type of odorous compounds. Among these, ammonia ($NH_3$) and hydrogen sulfide ($H_2S$) are the two known major odor causing substances. Because high odor concentration reduces productivity of livestock and causes damage to the surrounding communities, quantitative analysis is needed to manage the odor inside and outside the livestock facilities. It is also necessary to evaluate odor dispersion according to the distance between the receptors taking into account the influence of odor source and weather condition. Therefore, in this study, we tried to evaluate the internal environment and odor dispersion from experimental pig house considering weather conditions. An experimental farm was specifically selected to eliminate the interference of odors generated by adjacent farms. $NH_3$ and complex odor were quantitatively analyzed using a gas detector and air dilution sensory method. The concentration of $NH_3$ and complex odor in pig house showed a distinct concentration difference according to the cleaning and ventilation conditions. $NH_3$ concentration and complex odor was lower than emission standard in the pig house and at the site boundary. The average $NH_3$ concentration (P1~P3) and the $NH_3$ concentration at the site boundary (S1) were strongly correlated with R=0.77. While the correlation for complex odor inside and at the site boundary had R=0.52. The correlation coefficient between $NH_3$ and the complex odor was 0.80.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.32 no.1
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• pp.25-29
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• 2019

Various process technologies for manufacturing power inductors are under development. The core goal is to increase the mixing ratio of the soft magnetic powder in the epoxy, and to uniformly disperse it in a molding-type power inductor, manufactured by the injection molding method. In this study, we investigated the effect of dispersant and silane on the dispersion of soft magnetic metal powders in epoxy. We added 0.6 wt% of dispersant and 2.0 wt% of silane, and an excellent dispersibility resulted. Under the conditions of 0.3 wt% of dispersant and 0.5 wt% of silane, we added both dispersant and silane together to observe the effect of their interaction on dispersibility. Similarly, the addition of 0.3 wt% of dispersant and 0.1 wt% of silane resulted in a sharp increase in viscosity, considered to be due to the interaction of the dispersant and silane. The addition of 0.1 wt% of dispersant with 0.5 wt% of silane resulted in a sharp rise in viscosity, and sedimentation-height decreased sharply due to the dispersion optimization.