• 한국어병학회지
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• 제34권2호
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• pp.169-176
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• 2021

Parasitic infection is among the most common problems for carp cultivation. They are also important for the principal entrance of other hazardous infections as well. This study was carried out for determining of parasitic fauna of two major carp known as silver and grass carp with the comparison of prevalence value and intensity rate of parasites among them, alongside the relationship between the biometric characteristics and host sex with the infection level. For this purpose, a total of 94 fish samples were caught randomly using a fishing net, from Guilan ponds during spring and summer of the year 2018 and transported alive to the laboratory. Upon arriving, the biometric characteristics and genus of each carp were measured individually. Specimens were then acquired from the skin, gills, and eyes of the carp and examined according to standard parasitology methods. Recovered parasites were observed under a light microscope and then fixed for identification. As the result, the occurrence and intensity in the higher length group were comparatively greater than the lower one. Also, the prevalence and intensity of total parasites in male carp were higher than in females. In this research, Dactylogyrus hypophthalmichthys and Dactylogyrus aristhichtys were observed in silver carp and Dactylogyrus lamellatus was detected in grass carp. In the paper below, we found that the host specificity varies in different species of Dactylogyrus isolated from grass carp and silver carp.

• 한국멀티미디어학회논문지
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• 제25권8호
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• pp.1022-1037
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• 2022

It is important to develop a transducer that generates uniform output power through frequency control of the HIFU at 4 MHz frequency for the high intensity focused ultrasound (HIFU) skin diseases treatment. In this paper, a 4 MHz frequency band HIFU system for skin disease treatment was designed, manufactured and developed. In HIFU, even for the ultrasonic vibrator in the 4 MHz frequency band, the characteristics of the output power of the HIFU are different depending on the difference in the thickness of the PZT material. Through the development of a system amplifier, the sound output of the HIFU transducer was improved to more than 48 W and uniform output power control was possible. And, it is possible to control the output power even in a frequency band of 4.0 to 4.7 MHz, which is wider than 4.0 MHz, and shows the resonance frequency of the transducer. The maximum output power for each frequency was 49.969 W and the minimum value was 48.018 W. The maximum output power compared to the minimum output power is 49.969 W, which is uniform within 4.1%. It was confirmed that the output power of the HIFU through the amplifier can be uniformly controlled in the 4 MHz frequency band.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2003년도 제8차 학술대회 초록집
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• pp.34-34
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• 2003

Age-related WMCs frequently appear in older subjects and are known to be associated with cognitive impairment and brain pathologies such as Alzheimer's disease and stroke. However, it is difficult to detect WMC correctly by using only intensity-based clustering scheme because the intensity levels of WC are similar to those of gray matter(GM). In this paper, we aimed to develop a fast and accurate scheme to detect and segment periventricular WMCs by using both k-means clustering method and morphological features.

• 대한의용생체공학회:의공학회지
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• 제26권6호
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• pp.383-391
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• 2005

Age-related White Matter Changes (WMC) on Magnetic Resonance Imaging (MRI) are known to appear frequently in Multiple sclerosis (MS) and Alzheimer's disease and to be related to cognitive impairment. The characterization of these WMC is very important to the study of psychology and aging. These changes consist of periventricular and subcortical types, however it is difficult to detect and segment WMC using only intensity-based methods, because their intensity, level IS similar to th~t of the gray matter (GM). In this paper, we propose a new method of segmenting periventricular WMC using K-means clustering and morphological features.

• 대한안전경영과학회지
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• 제24권2호
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• pp.11-16
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• 2022

When picking up cargo, workers manually load and unload the cargo. Workers have different intensity of work depending on the amount and weight of cargo. In particular, as the intensity of manual work increases, workers are exposed to cumulative traumatic diseases. A manual for picking safety work for workers cargo handling in the distribution center is required. In this study, the worker's picking safety work based on the cargo volume and weight was presented as an experimental design model. Like the research results, the disease begins when the worker feels the number of pains presented by the model.

• Journal of Acupuncture Research
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• 제31권4호
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• pp.173-183
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• 2014

Objectives : The purpose of this study is to report the effect of Korean Medicine treatment on a patient with Charcot-Marie-Tooth disease. Methods : A 60-year-old woman who was diagnosed as Charcot-Marie-Tooth disease was admitted with both lower and upper limbs weakness, difficulty in walking, palm pain and neck pain. The patient was treated with acupuncture, electroacupuncture, herbal medicine, cupping therapy and physical treatment from 2th September 2013 to 14th November 2013. Improvement of the patient's symptoms was evaluated by numeric rating scale(NRS), visual analog scale(VAS), SF-36 bodily pain and patient global assessment(PGA). Results : After treatment, pain Intensity evaluated by VAS was significantly decreased(from 7.2 to 2). Increased SF-36 bodily pain score(from 10 to 67.5) showed that patient's quality of life has been improved. Conclusions : These results suggest that Korean medicine treatment may be effective in reducing the symptoms of Charcot-Marie-Tooth disease.

• 대한의생명과학회지
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• 제19권3호
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• pp.254-260
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• 2013

The purpose of this study was to survey the effects of Karvonen exercise prescription in coronary artery disease patients reaching age-predicted maximal heart rates with the exercise stress test on hemodynamic responses and cardiorespiratory fitness. The subject group was comprised of acute coronary syndrome (ACS) patients, who were divided into the maximal heart rate (MHR) group that included those who completed the test with their heart rates reaching the number of 220-age and the maximal dyspnea (MD) group that included those who could not continue the test due to respiratory difficulty and were asked to stop the test. Both groups had the exercise stress test before and after the experiment. In the exercise stress test before the experiment, the exercise prescription intensity of Karvonen was set at the target heart rates of 50~85% with a six-week exercise monitoring arrangement. As a result, there were no interactive effects in rest heart rate (RHR) according to time and group, but interactive effects were observed in maximal heart rate (MHR) (P=0.000). Both rest systolic blood pressure (RSBP) and rest diastolic blood pressure (RDBP) had no interactive effects according to time and group. Maximal systolic blood pressure (MSBP) showed significant interactive effects according to time and group (P=0.017). Maximal diastolic blood pressure (MDBP) showed no interactive effects according to time and group, while maximal rate pressure product (MRPP) showed significant interactive effects according to time and group (P=0.003). Maximal time (MT) had no interactive effects according to time and group. $VO_{2max}$ and maximal metabolic equivalent (MMET) showed significant interactive effects according to time and group (P=0.000, P=0.002, respectively), whereas maximal respiratory exchange ratio (MRER) and maximal rating of perceived exertion (MRPE) showed no interactive effects according to time and group. The exercise test that was discontinued as the subjects reached the predicted maximal heart rates considering age did not reach the maximal exercise intensity and accordingly showed low exercise effects when applied to Karvonen exercise prescription intensity. That is, the test should keep going by monitoring cardiac events, MRER and MRPE until the heart rates exceed the predicted MHR by up to 10~12 even after the subject reaches the predicted MHR considering age in the exercise stress test.

• Asian Pacific Journal of Cancer Prevention
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• 제15권19호
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• pp.8069-8073
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• 2014

Background: Hepatocellular carcinoma (HCC) is one of the most frequent cancers worldwide, with a high mortality. Most patients present with late stage disease, when the treatment options are limited to systemic chemotherapy. The purpose of our study was to evaluate the significance of p53 and EGFR expression in HCC, and to determine whether these two markers correlate with conventional parameters of prognosis. Materials and Methods: Our study included a total of 45 patients, diagnosed histopathologically with HCC. Clinicopathological data including sex, age, tumor necrosis, tumor size, histologic grading, tumor stage, the presence of cirrhosis and chronic hepatitis, were recorded from the Institute database. Three independent microscopic fields were selected for each sample and all the tumor cells within each microscopic field were counted, and then the positive percent of p53 cells were calculated. Three staining patterns were recognized: diffuse, heterogenous and focal. The intensity of EGFR staining was scored on a scale of 0-3+: 0 no staining; 1+ when a weak membrane staining was observed; 2+ when membrane staining is more intense than in 1+, but less than 3+, and 3+ when intense dark brown staining delineated the membrane. To determine the relationship between EGFR expression and p53, we performed double staining in the same HCC specimens. Results: By immunohistochemical staining, p53 protein was detected in tumor cell nuclei in 20 HCCs (44%). We found a significant correlation between the intensity of p53 expression and the histological grade (p=0.008). EGFR expression was detected in 17 (38%) cases, linked to histological grade (p=0.039). Moreover, the intensity of p53 expression was significantly correlated with EGFR intensity (p=0.014). Conclusions: Our results suggest that overexpression of p53 and EGFR plays an important role in hepatocarcinogenesis and contributes to more advanced disease. These markers are not only valuable predictors of prognosis in HCC, but they are also rational targets for new anti-tumor strategies.

• 한방안이비인후피부과학회지
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• 제13권2호
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• pp.140-151
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• 2000

Acne is a common chronic disease which most frequently affects the face, appearing in both males and females near puberty, and in most cases becomes less active as adolescence ends. The intensity and duration of activity vary for each individual. The disease may be minor, with only a few comedones or papules, or it may occur as the highly inflammatory and diffusely scarring acne conglobation. Permanent scarring of the skin and psyche can result from such inaction. The disease, however, has implications far beyond the few marks that may appear on the face. The lesions cannot be hidden under clothing; each is prominently displayed and detracts significantly from one's personal appearance and self-esteem. Recently many of acne patients are visiting to Oriental Medicine Hospitals. They want to receive the treatment of acne related another disease and causes, or worry about side effects of antibiotics and hormone therapy. This study was performed at Pundang Cha Oriental Medicine Hospital Department of Dermatology from March 1, 1997 to February 29, 2000 in 31 patients with recurrent acne. We investigated the clinical findings, included distribution of age & sex, severity of acne, sites on face, related causes, duration of disease and causes of visiting Oriental Medicine Hospital and so on. The results were as follows : The peak age at onset was 20-29 years old in females with 16 cases reported. The 22 total cases patients had severe signs with most frequently sites being forehead & chin. They visited Oriental Medicine Hospital because they want to take the treatment of acne related with another body problems(12 cases) and worry about side effects of antibiotics. Twenty cases were diagnosed 肺熱血熱(20 cases). And given acupuncture treatment, herb-medication and sometimes we used external applications. Relatively, their satisfaction grade was high. Dermatologists are trying to treat new methods in order to remove scar and decrease sebaceous gland secretion,. And we, Oriental Medicine doctors, have to develop and offer to patients the most effective management and successful treatment of this disease.

• 대한한의학회지
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• 제26권2호
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• pp.176-181
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• 2005

Objectives: This study was designed to evaluate the effect of moxibustion on UPDRS and heart rate variability of patients with Parkinson's disease. Methods: Subjects were voluntarily recruited through newspapers and internet. All subjects were confirmed as showing idiopathic Parkinson's disease by a neurologist. Moxibustion therapy was performed 5 times a week by the patient's family at home and once a week by an oriental medical doctor in hospital. Moxibustion points were GV20, CV12, ST36, BL18, and BL20. Intensity was up to pain threshold to prevent patients getting burned. The patient's symptoms were assessed before and after 8 weeks of treatment by unified Parkinson's disease rating scale (UPDRS). Heart rate variability was measured for 5 minutes before and after the treatments. Results: Total UPDRS scores were significantly improved after 8 weeks compared to pre-treatment (p<0.05). There were significant decrease of mean heart rates (p<0.05) and increase of SDNN and TP (p<0.05) after 8 weeks' moxibustion treatments. There were no significant changes in other components of heart rate variability. Conclusions: This study suggests that moxibustion treatments can be applicable to improve not only symptoms but also heart rate variability in the patients with idiopathic Parkinson's disease.