• 제목/요약/키워드: direct products

검색결과 943건 처리시간 0.033초

국산 생약 추출물의 항염증 활성 스크리닝 (Screening for Anti-inflammatory Activities in Extracts from Korean Herb Medicines)

  • 안상미;김형건;최은정;황형훈;이은석;백지훈;부용출;고재숙
    • 대한화장품학회지
    • /
    • 제40권1호
    • /
    • pp.95-108
    • /
    • 2014
  • 화장품은 일반인이 장기간 연용하는 제품으로 인체 피부에 대한 안전성이 매우 중요하다. 화장품에 의한 접촉피부염은 자극성 물질이 피부에 접촉 후 침투하여 유발하는 염증반응으로 활성화된 면역세포에서 염증을 매개하는 다양한 인자를 분비함으로써 시작된다. 본 연구에서는 국산 생약 추출물을 이용하여 RAW264.7 대식 세포에서 염증 관련 인자에 대한 영향을 통해 항염증 활성을 스크리닝 하였다. 51종의 국산 생약 추출물 중 측백, 측백엽(초), 향부자, 형개, 동과자, 산약, 산약(초), 상지, 송절, 택사의 에탄올 추출물 10종이 lipopolysaccharide(LPS)에 의해 유도된 세포독성을 감소시킴과 동시에 염증 관련 인자인 Nitric oxide (NO), interleukin (IL)-1${\beta}$, IL-6, tumor necrosis factor (TNF)-${\alpha}$의 생성을 억제하는 것을 확인하였다. 또한, 이들 생약 추출물은 인체피부에서도 자극을 유발하지 않음을 인체 첩포시험을 통해 검증하였다. 따라서, 항염증 활성이 확인된 10종 국산 생약 추출물은 피부 자극을 예방할 수 있는 화장품 소재로서의 활용이 가능할 것으로 사료된다.

농특산품 전시판매장 디자인 현황 분석 및 유형별 분석 - 농촌관광마을 현장조사 및 농업인 공급자 의식조사를 중심으로 - (Analysis of Design Status by Type at Display Store of Regional Agricultural Products: Focusing on the Survey of Farming Suppliers' Attitude and Site Examination of Rural Tourism Village)

  • 진혜련;채혜성;강가혜;조록환
    • 농촌계획
    • /
    • 제19권3호
    • /
    • pp.13-24
    • /
    • 2013
  • With the increase of visitors to rural tourism villages, the direct selling at sites is getting vitalized. Accordingly, their display stores is getting more important. Therefore, this study has selected 30 domestic rural tourism villages as study objects for the attitude survey of 200 farming suppliers and the site examination for the designs of those display stores in order to analyze their status and classify the types of necessity. Such operation status as sale item, sale method, method of supply and demand, major customer, sales scale, manager, opening hour, and operation cost were examined, to identity and for design factors the pattern, material quality and color were investigated. For the attitude of farming suppliers, the tactics of sales, the reason for being positive or negative, the functionality and the features of display stores were examined through brainstorming. IBM SPSS Statistics 20 Program was employed for Frequency, which indicated that village chiefs and store managers with the sales scale of 1 to 20 million won are dealing with female customers in their 40's and 50's and that those stores are open at the time of experience or year round without any operation expense. Permanent type and Fixed type were found to be the design factors of the display-case type with the material and the color of wood and orange respectively. The result of investigation analysis of farming suppliers' attitude showed the followings: the need of display stores is quite high, structure type and permanent type have high fitness and from the viewpoint of display-on-table type as a standard moving type was very convenient. The analysis of significant items at the characteristics of those display stores revealed that their locations, quality conservation, sanitation, users' convenience, designs and promotion are very important. The result of status analysis revealed that though there is a correlation among the types of display stores depending on the visiting season of tourists their installing is not desirable. Three types have been analyzed: Type 1 is a structure type only in the villages with continuous visitors, Type 2 a moving-table type only in the villages with temporary visitors and Type 3 is a fixed display-case type.

기사 구성과 특징으로 본 '문화 저널리즘'의 변화상과 함의 주요 일간지 문화면의 내용분석을 중심으로 (Tracing the Changes of Cultural Journalism in Korea Content Analyses of Major Newspapers)

  • 김경희;이기형;김세은
    • 한국언론정보학보
    • /
    • 제74권
    • /
    • pp.136-176
    • /
    • 2015
  • '문화 저널리즘'은 광의의 저널리즘의 한 분파이자 확립된 유형으로 존재해왔지만, 학술영역에서 문화 저널리즘의 특징과 현황을 분석하는 작업은 매우 희소하다. 이 연구는 제도언론 영역에서 추구되는 문화 저널리즘의 위상과 현황 그리고 실천이 과거와 비교해서 어떻게 달라졌는지를 파악하기 위해서 주요 일간지 문화면에 관한 내용분석을 실시했으며, 관련 학술자료와 기사들을 통한 질적인 해석을 함께 활용하였다. 분석 결과, 10년 전(2003~2004년)과 비교하여 현재(2013~2014년)의 신문 지면은 늘어난 데 반해, 문화 관련 기사의 전체 게재량은 감소했으며, 문화면 이외의 종합면 등 타 지면에 게재된 기사의 비율 또한 줄어들었다. 한편, 문화 콘텐츠에 중심을 두고 보도된 기사와 '지식 교양' 또는 '여가 오락'으로서 문화에 접근하는 관점의 기사들은 줄어든 반면, 문화현상을 '상품(광고)'과 '생활'로서 접근하는 기사들이 늘어났다. 이와 함께 '비평 리뷰 해설'을 담아내는 기사가 통계적으로 유의미하게 감소한 것으로 나타났다. 또한 문화 저널리즘의 중요한 기반으로 간주할 수 있는 '학술'과 '공연 전시 미술 음악' 같은 주제를 다루는 기사들은 줄어들었으며, 대중문화와 여행, 패션, 미용 등의 광의의 라이프스타일을 다루는 연성적인 주제들이 상당히 증가한 것으로 드러났다. 그리고 독자와 관객을 포함하는 수용자들의 기고가 일부 늘어났다는 점 외에 기고자의 선정이나 직업적인 특성에서 유의미한 수준의 변화는 관찰되지 않았으며, 독자를 직접 인용원으로 삼는 기사가 부분적으로 증가했다는 점 외에 직접 인용 취재원의 활용에서도 별다른 변화는 없었다. 이러한 연구 결과를 통해 볼 때, 문화콘텐츠의 역할이 크게 주목받는 사회문화적인 상황과는 달리 종합일간지 지면에서 이루어지는 문화 관련 보도와 기사의 생산은 양식적인 다양성과 구성적인 차별화 그리고 광의의 비평적인 관점의 제시라는 측면에서 상당한 한계를 드러내는 것으로 판단된다.

  • PDF

LiDAR 데이터를 이용한 등고선 제작의 효율성 평가 (Efficiency Evaluation of Contour Generation from Airborne LiDAR Data)

  • 위광재;이임평;강인구;조재명
    • 대한공간정보학회지
    • /
    • 제15권2호통권40호
    • /
    • pp.59-66
    • /
    • 2007
  • 최근 들어 디지털 기반의 산업환경 변화와 더불어 관련 기술의 변화가 급속히 진행되고 있다. 측량분야에서도 과거 단순히 항공사진을 이용하여 도화를 하던 방식에서 벗어나 GPS 및 INS 등의 멀티센서 및 디지털 카메라를 이용한 디지털 방식의 작업환경이 도입되고 있다. 지형에 대한 정확한 데이터는 국토의 효율적 이용 및 관리, 도시계획 수립, 환경 및 재난관리 등 여러 분야에서 광범위하게 활용되고 있으며 지식정보시대의 필수적인 정보인프라로 인식되고 있다. 본 연구에서는 수목 등에 투과성이 우수하며 비행설계에서부터 최종성과물까지 디지털 방식으로 정확 신속하게 데이터를 산출할 수 있는 항공레이저측량을 이용하여 지형정보를 취득하였으며, 이를 통해 제작된 등고선과 항공사진 도화에 의한 현행 수치지형도(1/1,000 및 1/5,000의 등고선을 비교하여 그 정확도와 세밀도 및 경제적 관점에서 효율성을 평가하였다. GPS측량에 의한 정확도 평가 결과, LiDAR 데이터의 표고 정확도는 평균 $0.089m{\pm}0.062m$로써 1/1,000 수치지형도보다 우수하게 나타났으며, 복잡한 도시의 지물을 보다 더 세밀하게 표현할 수 있었다. 경제적 측면에서는 현행 항공사진 도화에 의한 1/1,000 수치지형도 등고선 제작비용($100km^2$ 기준)과 비교하여 약 48%의 비용절감 효과를 나타냈다. 본 연구결과, 갱신주기가 수년에 이르는 수치지형도의 수정 갱신이 미흡한 현재의 상태에서 항공레이저측량에 의하여 획득된 LiDAR 데이터를 이용할 경우에 등고선의 최신성 및 현시성을 충족시킬 수 있는 대안임을 보여 주었다.

  • PDF

마케팅 부서의 조절초점과 신제품 개발 창의성: 창의성 증진수단의 조절효과 (Marketing Organization's Regulatory Focus and NPD Creativity: The Moderating Role of Creativity Enhancement Tools)

  • 강성호;손정민
    • 유통과학연구
    • /
    • 제14권7호
    • /
    • pp.71-81
    • /
    • 2016
  • Purpose - Because creativity, which is an intangible resource embedded within the company, can offer a competitive advantage, most companies have an interest in promoting creativity among their employees and division(e.g., marketing organization). Creativity renders a sustainable competitive advantage to a firm because it is a strategic resource that is valuable, flexible, rare, and imperfectly imitable or substitutable. Although most companies broadly recognize the importance of creativity, the methods for developing creativity remain elusive. Therefore, the present study investigates how to structure incentives to motivate employees to be more creative and how to develop tools to facilitate creativity. In detail, the present study aimed to examine the relationship between the regulatory focus of marketing organizations(e.g., promotion focus vs prevention focus) and creativity of marketing organizations. In addition, the present study set out to examine the moderating role of interaction of financial reward and creative training in addition to investigating the direct relationship between creativity and regulatory focus in New Product Development(NPD) context. Research design, data, and methodology - The data used to test the hypotheses are drawn from a survey of full time NPD project members(including project manager, designer, engineer, and marketer). The present study utilized data obtained mainly from a database compiled by the Korea Investors Service-Financial Analysis System which provides comprehensive corporate and financial information on firms listed on the Korea Stock Exchange. A study population comprising 1,000 South Korean firms was obtained from this database. We selected 864 firms from the database, and the firms have experiences of new product development project. We collected a total of 162 responses, for a 18.8% response rate. After we excluded 14 questionnaire because of incomplete responses, a total of 148 questionnaire remained(final response rate: 17.1%). Working with a sample of 148 responses in South Korea, hierarchical moderated regression is employed to test research hypotheses(

    The relationship between promotion focus and creativity of marketing organization,

    The relationship between prevention focus and creativity of marketing organization,

    The moderating effect of joint influences(interaction between financial rewards and creativity training) on the relationship between promotion focus creativity of marketing organization,

    The moderating effect of joint influences(interaction between financial rewards and creativity training) on the relationship between prevention focus creativity of marketing organization). SPSS 18.0 and AMOS software were used in the data analysis. Results - The empirical study confirmed that promotion focus of marketing organization is positively related to creativity of marketing organization. Also, prevention focus of marketing organization is positively affected to creativity of marketing organization. In addition, the interaction between financial rewards and creativity training moderated the relationship between regularity focus(e.g.), promotion focus vs prevention focus) and creativity of marketing organization. These results suggest that managers can improve the performances of their creative efforts by providing the use of financial rewards and creativity training in combination. Conclusion - Based on results of this study that examine the effects of regulatory focused creative efforts on creativity of marketing organization, promotion focus is helpful with marketing organizations to enhance their service innovation and performance. Prevention focused organization should allow monetary rewards and creativity training to increase their creativity for innovation of new products.

Supplementing Rhodobacter sphaeroides in the diet of lactating Holstein cows may naturally produce coenzyme Q10-enriched milk

  • Bae, Gui-Seck;Choi, Ahreum;Yeo, Joon Mo;Kim, Jong Nam;Song, Jaeyong;Kim, Eun Joong;Chang, Moon Baek
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제31권1호
    • /
    • pp.40-46
    • /
    • 2018
  • Objective: To examine the effects of Rhodobacter sphaeroides (R. sphaeroides) supplementation as a direct-fed microbial (DFM) on rumen fermentation in dairy cows and on coenzyme Q10 (CoQ10) transition into milk, an in vitro rumen simulation batch culture and an in vivo dairy cow experiment were conducted. Methods: The characteristics of in vitro ruminal fermentation were investigated using rumen fluids from six cannulated Holstein dairy cows at 2 h post-afternoon feeding. A control treatment was included in the experiments based on a typified total mixed ration (TMR) for lactating dairy cows, which was identical to the one used in the in vivo study, plus R. sphaeroides at 0.1%, 0.3%, and 0.5% TMR dry matter. The in vivo study employed six ruminally cannulated lactating Holstein cows randomly allotted to either the control TMR (C-TMR) treatment or to a diet supplemented with a 0.5% R. sphaeroides culture (S-TMR, dry matter basis) ad libitum. The presence of R. sphaeroides was verified using denaturing gradient gel electrophoresis (DGGE) applied to the bacterial samples obtained from the in vivo study. The concentration of CoQ10 in milk and in the supernatant from the in vitro study was determined using high performance liquid chromatography. Results: The results of the in vitro batch culture and DGGE showed that the concentration of CoQ10 significantly increased after 2 h of R. sphaeroides supplementation above 0.1%. When supplemented to the diet of lactating cows at the level of 0.5%, R. sphaeroides did not present any adverse effect on dry matter intake and milk yield. However, the concentration of CoQ10 in milk dramatically increased, with treated cows producing 70.9% more CoQ10 than control cows. Conclusion: The CoQ10 concentration in milk increased via the use of a novel DFM, and R. sphaeroides might be used for producing value-added milk and dairy products in the future.

WTO 통상환경 하에서 서비스부문의 세계화 모드에 관한 고찰 (A Study on the Globalization of Services Under the WTO System.)

  • 채대석
    • 통상정보연구
    • /
    • 제7권3호
    • /
    • pp.287-300
    • /
    • 2005
  • The globalization of services is closely related to other economic problems facing the world today. These are: 1) the globalization of economic activities, 2) the servicization of economic activities. The world economy is now move interconnected than at any time in its history. Investment decisions, production processes, labor market regulations and even environmental legislation made by one country or company affect other economies, other companies and the lives of individuals. In fact, it is nearly impossible to think of a country that is not connected to the world economy in some form or another and it is no exaggeration to state that globalization is already an unassailable fact. The fabric of our economy and the way we do business are changing. This change is the transformation from a marketplace on goods to one focused on services. That is to say, we live and work in a service-centered, service-sensitive economy. As a result of the globalization an servicization of economic activities, services require the globalization, and services are increasing their international trade, foreign investment, agreements, alliances, mergers and collaboration networks. It is quite obvious that services are affected by globalization ; but raising the question by how much leads us to the paradox of service globalization, services represent 70% of the most advances economies but only account for less than 25% of international trade and almost half of direct investment; mergers and takeovers. These figures create a paradox that can be explained by two reasons. First; the natural(the service relationship) and artificial difficulties(barriers to trade) faced by the service sector that inhibits globalization. Second, the non-inclusion in official statistics of the share of internationalized goods that are due to services, for example intra-firm trade or the service value incorporated into exported goods. If these were taken into account the service trade figures would be extremely different. The first explanation can be subdivided into a number of elements. The OECD identifies six reasons:services cannot be stored; client-supplies interaction requires local presence; most service firms are SEMs; products are highly differentiated; cultural differences are especially important in this field; and, finally, trade barriers and restrictions on local operations exist. However, despite all of this, globalization produces clear advantages to suppliers. Therefore, the objective of this study is to explore the main forms of service globalization and differences between that of goods, and is to identify distinctive aspects of service globalization within the framework of the global economy.

  • PDF

인체 노로바이러스의 한국분리주 Hu/NLV/Gunpo/2006/KO의 분자생물학적 특성 (Molecular Characterization of a Korean Isolate of Human Norovirus, the Hu/NLV/Gunpo/2006/KO Strain)

  • 정아용;윤상임;지영미;강윤성;이영민
    • 미생물학회지
    • /
    • 제45권2호
    • /
    • pp.105-111
    • /
    • 2009
  • 노로바이러스는 급성 위장염을 일으키는 Caliciviridae 과(family)에 속하는 바이러스로 유전자형이 매우 다양하다. 본 연구에서는 노로바이러스 국내분리주의 게놈 RNA로부터 3개의 open reading frame (ORF) 모두의 염기서열을 분석하고, 유전학적 계통분석을 통하여 분자생물학적 특성을 분석하였다. 본 연구에 사용된 노로바이러스(Hu/NLV/Gunpo/2006/KO)는 바이러스성 식중독, 장염 증세를 보이는 2세 여아 가검물로부터 분리되었다. 역전사반응과 PCR 증폭을 통해서 바이러스의 게놈 RNA를 3개의 중첩되는 cDNA 단편으로 합성하였으며, 합성된 cDNA를 염기서열 분석에 직접 사용하였다. 시퀀싱 결과 Hu/NLV/Gunpo/2006/KO는 3개의 ORF (ORF1, 5,100 bp; ORF2, 1,647 bp; ORF3, 765 bp)로 구성되어 있음을 알 수 있었다. 35개의 노로바이러스 국외 분리주와 비교한 결과, ORF1은 ORF2 또는 ORF3에 비해서 상대적으로 염기의 변이율이 낮았으며, 특히 ORF2와 ORF3의 C-말단 부위에서 높은 변이율을 관찰하였다. 유전학적 계통도를 분석한 결과, Hu/NLV/Gunpo/2006/KO는 genogroup II 에 속하며, Saitama U1, Gifu'96, Mc37, Vietnam 026과 같은 클러스터를 형성하는 것을 알 수 있었다. 본 연구를 통하여 노로바이러스 Hu/NLV/Gunpo/2006/KO의 3개의 ORF 염기서열을 모두 밝힘으로써, 앞으로 노로바이러스의 검출법 개발과 유전학적 상관관계뿐 아니라, 유전자의 기능 분석과 관련된 기초연구에 중요한 기초자료를 제공할 수 있을 것으로 기대한다.

임도(林道)의 생산력적(生産力的) 의의(意義)와 경제적(經濟的) 효용(效用) (Significance of Forest Road on the Productive Potency and It's Economic Utility)

  • 박명규
    • 한국산림과학회지
    • /
    • 제65권1호
    • /
    • pp.107-112
    • /
    • 1984
  • 임도(林道)의 효용(效用)에 대(對)한 이론적(理論的)인 고찰(考察)은 임업(林業)의 근대화(近代化) 활성화(活性化)를 지향(指向)하는 현시점(現時點)에서 의의(意義)있는 일이라 사료(思料)된다. 1) 임도(林道)는 목재(木材)의 생산기술적(生産技術的) 견지에서 보면 각종(各種) 임산물(林産物)의 경제적(經齊的) 반출(搬出)을 가능(可能)하게 하며 작업용(作業用) 기계(機械)와 필요자재(必要資材)의 임내(林內) 반입(搬入)을 용이(容易)하게 하고 조림(造林) 무육(撫育) 보호(保護) 보전(保全) 등 제작업(諸作業)의 능률화(能率化)에 기여도가 크다. 2) 또한 삼림(森林)의 관리(官理) 경영적(經營的) 견지에서 보면 임도(林道)의 발달(發達)에 의해서 목재(木材)의 시장성(市場性)이 확보(確保)되고 업무(業務)의 능률화(能率化)에 따르는 각종(各種) 간접(間接) 경비(經費)의 절감(節減)을 가능(可能)케 한다. 3) 산촌주민(山村住民)의 생활(生活)면에 있어서도 임업노동(林業勞動)의 세업개선(歲業改善), 산촌교통(山村交通)의 변익(便益) 문화(文化)의 도입(導入) 등 주민(住民)의 복지증진(福祉增進)에 직간접(直間接)으로 역할(役割)하게 되며 그 효용(效用)이 크게 기대(期待)되고 있다. 따라서 집약적(集約的) 임업경영(林業經營)을 실현(實現)하는 전제(前提)로서 임도(林道)는 중요(重要)하고도 기초적(基礎的)인 시설(施設)일 뿐만 아니라 생산기반(生産基盤)으로서 그 필요성(必要性)이 더해가고 있다.

  • PDF

스마트폰 기반 증강현실 특성이 프레즌스, 플로우 및 관계지속행동에 미치는 영향 (The Effect of Augmented Reality Traits on Presence, Flow, and Relational Continuance Behavior with Smart-Phones)

  • 전태유;박노현
    • 유통과학연구
    • /
    • 제13권5호
    • /
    • pp.45-52
    • /
    • 2015
  • Purpose - Augmented reality (AR) content used in mobile media today can accommodate a wide variety of contextual information. This indicates that making people experience a sense of presence and flow is a very significant factor in augmented reality content. Flow represents a rich immersion potential as representing the progress of emotion and the means to facilitate the operation of the smart phone. Therefore, users will have friendly relational continuance behavior with products and brands that supply this experience. Based on that, the purpose of this study is to investigate the relationships among smart phone AR application traits, presence, flow experience, and relational continuance behavior. First, AR application traits are defined as three categories sensory immersion, navigation, and manipulation, based on preceding studies. This study then examines the influence of AR application traits on the presence and flow experience and looks into the relation among presence, flow experience, and relational continuance behavior. This analysis suggests more detailed and concentrated strategic implications. Research design, data, and methodology - A research model is designed to examine the relation among AR application traits, presence, flow experience, and relational continued behavior. For data collection, questionnaire surveys were composed of multi-items for each component and the direct interview method was used for the interviews. To collect the data, after running the smart phone AR applications, the consumer behaviors of the respondents were generally determined. The questionnaire surveys were conducted for one month, October 2014. A total of 300 questionnaires were distributed with 278 questionnaires used for analysis, excluding the unanswered and insincere questionnaires. The data were analyzed using SPSS ver. 20.0 and LISREL ver. 8.51. Results - The following results are found: First, AR application traits have a significantly positive effect on presence with sensory immersion, navigation, and manipulation all having a significantly positive effect. Second, sensory immersion and manipulation among the AR application traits have a significantly positive effect on flow. However, navigation did not have a significantly positive effect on flow. Third, presence has a significantly positive effect on flow and has a significantly positive effect on relational continuance behavior. Moreover, flow also has a significantly positive effect on relational continuance behavior. This behavior tends to be formed since brands want to encourage relational continuance behavior and positive emotions with the brands being used. Relational continuance behavior accompanies repeat purchasing, positive word-of-mouth and recommendation activities, and forms of trust with the brand. Conclusions - The research results showed that smart phone AR traits had significantly positive effect on presence, flow, and relational continuance behavior. Based on this, smart phone AR application providers should establish an aggressive marketing strategy to accommodate more realistic problems in order to positively influence user behavior. Additionally, the marketers should make efforts to provide fun or convenience in the AR application operation process of the user.