• Journal of KIISE:Software and Applications
• /
• v.33 no.4
• /
• pp.365-377
• /
• 2006

Proteins are known to perform a biological function by interacting with other proteins or compounds. Since protein interaction is intrinsic to most cellular processes, prediction of protein interaction is an important issue in post-genomic biology where abundant interaction data have been produced by many research groups. In this paper, we present an associative feature mining method to predict implicit protein-protein interactions of Saccharomyces cerevisiae from public protein interaction data. We discretized continuous-valued features by maximal interdependence-based discretization approach. We also employed feature dimension reduction filter (FDRF) method which is based on the information theory to select optimal informative features, to boost prediction accuracy and overall mining speed, and to overcome the dimensionality problem of conventional data mining approaches. We used association rule discovery algorithm for associative feature and rule mining to predict protein interaction. Using the discovered associative feature we predicted implicit protein interactions which have not been observed in training data. According to the experimental results, the proposed method accomplished about 96.5% prediction accuracy with reduced computation time which is about 29.4% faster than conventional method with no feature filter in association rule mining.

• Journal of Institute of Control, Robotics and Systems
• /
• v.16 no.12
• /
• pp.1150-1158
• /
• 2010

In this study, the Polynomial-based Radial Basis Function Neural Networks is proposed as one of the recognition part of overall face recognition system that consists of two parts such as the preprocessing part and recognition part. The design methodology and procedure of the proposed pRBFNNs are presented to obtain the solution to high-dimensional pattern recognition problem. First, in preprocessing part, we use a CCD camera to obtain a picture frame in real-time. By using histogram equalization method, we can partially enhance the distorted image influenced by natural as well as artificial illumination. We use an AdaBoost algorithm proposed by Viola and Jones, which is exploited for the detection of facial image area between face and non-facial image area. As the feature extraction algorithm, PCA method is used. In this study, the PCA method, which is a feature extraction algorithm, is used to carry out the dimension reduction of facial image area formed by high-dimensional information. Secondly, we use pRBFNNs to identify the ID by recognizing unique pattern of each person. The proposed pRBFNNs architecture consists of three functional modules such as the condition part, the conclusion part, and the inference part as fuzzy rules formed in 'If-then' format. In the condition part of fuzzy rules, input space is partitioned with Fuzzy C-Means clustering. In the conclusion part of rules, the connection weight of pRBFNNs is represented as three kinds of polynomials such as constant, linear, and quadratic. Coefficients of connection weight identified with back-propagation using gradient descent method. The output of pRBFNNs model is obtained by fuzzy inference method in the inference part of fuzzy rules. The essential design parameters (including learning rate, momentum coefficient and fuzzification coefficient) of the networks are optimized by means of the Particle Swarm Optimization. The proposed pRBFNNs are applied to real-time face recognition system and then demonstrated from the viewpoint of output performance and recognition rate.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• v.26 no.6
• /
• pp.628-635
• /
• 2000

The purpose of this study was to evaluate the result after 2-phase surgical-orthodontic treatment without preoperative orthodontic treatment for the skeletal Cl III malocclusion patient and to obtain an adequate protocol on the bases of this result. This retrospective study of ten patients who underwent 2-phase treatment were done to evaluate 1) the surgical stability and relapse pattern 2) the facial esthetics 3) the TMJ problem 4) the total time of the treatment. Results were followed : 1) The horizontal relapse of the mandible was 26.8% and didn't show significant differences compared to the conventional 3-phase treatment. But, it was considered that this amount of relapse was the sum of true relapse and autoratation of mandible due to decreased vertical dimension during orthodontic treatment. 2) It was estimated that there's no difference on the ratio of anterior facial height between the subjects and the normal patients. On the horizontal analysis, the mandible of the subjects was located more anteriorly than that of the normal patients. This result showed that there was a need for the accurate preoperative esthetic evaluation and the additional methods for reducing the relapse due to the occlusal interference. 3) Wide variation was noted on the TMJ symptoms of the subjects, however, it was estimated that there's no significant differencees of symptoms compared to that of the conventional 3-phase treatment on literatures. 4) The average of the overall period of treatment was 20.8 months and we obtained reduction of the treatment time compaired to 3-phase treatment on many literatures. Most of the results of this study were similar to the findings of the 3-phase treatment(preoperative orthodontic-orthognathic surgery-postoperative orthodontic), but total time of the treatment was shorter in patients with 2-phase treatment than in those with the conventional 3-phase treatment. With 2-phase treatment, we experienced many advantages compared to the conventional method considering that it was favarable conditions for the teeth, it had the flexibility for the treatment, and it could be the adequate treatment approach for the stomatognathic system. Although this retrospective pilot study had some limitations, due to small samples, the authors would hope that it could serve as a guide for the future researches, and the clinical applications.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.28 no.12
• /
• pp.933-940
• /
• 2017

A wireless power transfer system with a negative impedance converter(NIC) was designed and tested. The system was investigated to identify the effects of ferrites and conductors. To improve the power transfer efficiency(PTE), the Q-factor of the transmitter was enhanced by the negative resistance generated by the NIC. The NIC was composed of an Op-Amp and resistors. The negative resistance was obtained with respect to a resistor connected in a feedback loop. The dimension of the Tx coil was $250mm{\times}250mm{\times}0.8mm$. The impedance and Q-factor were $31+j1874{\Omega}$ and 60, respectively. The negative resistance was selected to be $30{\Omega}$, and the Q-factor was increased to 900 by reduction of the transmitter resistance, which was about 15 times higher than that of a conventional transmitter. The measured PTE was greatly improved in comparison to that of a conventional system. These results demonstrate that the PTE is enhanced by using the NIC.

• 한국정보디스플레이학회:학술대회논문집
• /
• 2008.10a
• /
• pp.993-994
• /
• 2008

Electrochromic (EC) devices are capable of reversibly changing their optical properties upon charge injection and extraction induced by the external voltage. The characteristics of the EC device, such as low power consumption, high coloration efficiency, and memory effects under open circuit status, make them suitable for use in a variety of applications including smart windows and electronic papers. Coloration due to reduction or oxidation of redox chromophores can be used for EC devices (e-paper), but the switching time is slow (second level). Recently, with increasing demand for the low cost, lightweight flat panel display with paper-like readability (electronic paper), an EC display technology based on dye-modified $TiO_2$ nanoparticle electrode was developed. A well known organic dye molecule, viologen, was adsorbed on the surface of a mesoporous $TiO_2$ nanoparticle film to form the EC electrode. On the other hand, ZnO is a wide bandgap II-VI semiconductor which has been applied in many fields such as UV lasers, field effect transistors and transparent conductors. The bandgap of the bulk ZnO is about 3.37 eV, which is close to that of the $TiO_2$ (3.4 eV). As a traditional transparent conductor, ZnO has excellent electron transport properties, even in ZnO nanoparticle films. In the past few years, one-dimension (1D) nanostructures of ZnO have attracted extensive research interest. In particular, 1D ZnO nanowires renders much better electron transportation capability by providing a direct conduction path for electron transport and greatly reducing the number of grain boundaries. These unique advantages make ZnO nanowires a promising matrix electrode for EC dye molecule loading. ZnO nanowires grow vertically from the substrate and form a dense array (Fig. 1). The ZnO nanowires show regular hexagonal cross section and the average diameter of the ZnO nanowires is about 100 nm. The cross-section image of the ZnO nanowires array (Fig. 1) indicates that the length of the ZnO nanowires is about $6\;{\mu}m$. From one on/off cycle of the ZnO EC cell (Fig. 2). We can see that, the switching time of a ZnO nanowire electrode EC cell with an active area of $1\;{\times}\;1\;cm^2$ is 170 ms and 142 ms for coloration and bleaching, respectively. The coloration and bleaching time is faster compared to the $TiO_2$ mesoporous EC devices with both coloration and bleaching time of about 250 ms for a device with an active area of $2.5\;cm^2$. With further optimization, it is possible that the response time can reach ten(s) of millisecond, i.e. capable of displaying video. Fig. 3 shows a prototype with two different transmittance states. It can be seen that good contrast was obtained. The retention was at least a few hours for these prototypes. Being an oxide, ZnO is oxidation resistant, i.e. it is more durable for field emission cathode. ZnO nanotetropods were also applied to realize the first prototype triode field emission device, making use of scattered surface-conduction electrons for field emission (Fig. 4). The device has a high efficiency (field emitted electron to total electron ratio) of about 60%. With this high efficiency, we were able to fabricate some prototype displays (Fig. 5 showing some alphanumerical symbols). ZnO tetrapods have four legs, which guarantees that there is one leg always pointing upward, even using screen printing method to fabricate the cathode.

• Journal of the Korean Institute of Gas
• /
• v.2 no.4
• /
• pp.60-66
• /
• 1998

The hot stove system is a process that is continuously and constantly generating the hot combustion air required for the blast furnace. The hot stove process is considered as a main energy consumption process because it consumes about $20\%$ of the total energy in steel making works. So, many researchers have interested in the improvement of the heat efficiency of the hot stove to reduce the energy consumption. But they have difficulties in improving the heat efficiency of the hot stove because there is no precise information on heat transformation occurring during the heating period. In order to model the relationship between the operating conditions and heat efficiencies, we propose a neural network using feature extraction as one of experimental modeling methods. In order to show the performance of the model, we compare it with Partial Least Square (PLS) method. Both methods have similarities in using the dimension reduction technique. And then we present the simulation results on the prediction of the heat efficiency of the hot stove.

• Journal of the Institute of Electronics Engineers of Korea SD
• /
• v.42 no.9 s.339
• /
• pp.51-60
• /
• 2005

The design of efficient cryptosystems is mainly appointed by the efficiency of the underlying finite field arithmetic. Especially, among the basic arithmetic over finite field, the rnultiplicative inversion is the most time consuming operation. In this paper, a fast inversion algerian in finite field $GF(2^m)$ with the standard basis representation is proposed. It is based on the Extended binary gcd algorithm (EBGA). The proposed algorithm executes about $18.8\%\;or\;45.9\%$ less iterations than EBGA or Montgomery inverse algorithm (MIA), respectively. In practical applications where the dimension of the field is large or may vary, systolic array sDucture becomes area-complexity and time-complexity costly or even impractical in previous algorithms. It is not suitable for low-weight and low-power systems, i.e., smartcard, the mobile phone. In this paper, we propose a new hardware architecture to apply an area-efficient and a synchronized inverter on low-complexity systems. It requires the number of addition and reduction operation less than previous architectures for computing the inverses in $GF(2^m)$ furthermore, the proposed inversion is applied over either prime or binary extension fields, more specially $GF(2^m)$ and GF(P) .

• The korean journal of orthodontics
• /
• v.23 no.2 s.41
• /
• pp.217-227
• /
• 1993

Preadjusted appliance, following the original concept of the Andrews Straight-Wire appliance, became increasingly common in the 1980s. In six phases of treatment, anchorage control, leveling and aligning, overbite control, overjet reduction, space closure, and finishing are very effective with using the preadjusted appliances. Space closure is the phase of treatment in which the difference between standard edgewise and preadjusted mechanics is most noticeable. Orthodontists have been able to reduce the use of closing loops and, because of the level slot lineup, enjoy the advantages of sliding mechanics. In 1990, Dr. John C. Bennett and Richard P. McLaughlin introduced the new space closure system, namely, elastic 'tiebacks'. They found an $.019'\times.025'$ working archwire most effective in an .022'-slot system. Hooks of .024' stainless steel or .028' brass wire are soldered to the upper and lower archwires. The force required for space closure is delivered by elastic 'tiebacks'. An elastic modulo stretched by 2-3mm(to twice its normal length) usually delivers 0.5-1.5mm of space closure per month. Group movement and sliding mechanics are combined for gentle, controlled space closure, so that about 0.5mm of incisor retraction and 0.5mm of mesial molar movement can be seen each month. The tiebacks are replaced every four to six weeks. By using the elastic 'tiebacks', the next two cases were treated during space closure. Even though we found some clinical problems of this mechanics, long treatment time, hard to control of vertical dimension and anchorage, the application method of this system is so simple that orthodontists can manage many patients during short chair time. But we must apply this mechanics after perfect understanding of the biomechanics in tooth movement.

• Restorative Dentistry and Endodontics
• /
• v.22 no.1
• /
• pp.428-446
• /
• 1997

Restorative procedures can lead to weakening tooth due to reduction and alteration of tooth structure. It is essential to prevent fractures to conserve tooth. The resistance to fracture of the restored tooth may be influenced by many factors, among these are the cavity dimension and the physical properties of the restorative material. The placement of direct composite resin restorations has generally been found to have a strengthening effect on the prepared teeth. It is the purpose of this investigation to study the relationship between the cavity isthmus and the fracture resistance of a tooth in composite resin restorations. In this study, MO cavity was prepared on maxillary first premolar. Three dimensional finite element models were made by serial photographic method and isthmus(1/4, 1/3, 1/2 of intercuspal distance) were varied. Two types of model(B and R model) were developed. B model was assumed perfect bonding between the restoration and cavity wall and R model was left unfilled. A load of 500N was applied vertically at the first node from the lingual slope of the buccal cusp tip. This study analysed the displacement, 1 and 2 direction normal stress and strain with FEM software ABAQUS Version 5.2 and hardware IRIS 4D/310 VGX Work-station. The results were as follows : 1. Displacement of buccal cusp in R model occurred and increased as widening of the cavity, and displacement in B model was little and not influenced by cavity width. 2. There was a significant decrease of stress resulting in increase of fracture resistance in B model when compared with R model. 3. With the increase of the isthmus width, B model showed no change in the stress and strain. In R model, the stress and strain increased both in the area of buccal-pulpal line angle and the buccal side of marginal ridge, therefore the possibility of crack increased. 4. The stress and strain were distributed evenly on the tooth in B model, but in R model, were concentrated on the buccal side of the distal marginal ridge and buccal-pulpal line angle, therefore the possibility of fracture increased.

• Journal of Acupuncture Research
• /
• v.35 no.4
• /
• pp.193-199
• /
• 2018

Background: The purpose of this study was to investigate electric moxibustion on patients with back pain caused by road traffic accidents. Methods: This was a retrospective study (n = 112) comparing treatment with Korean medicine combined with electric moxibustion (n = 56), and Korean medicine alone (n = 56). Patient gender, age, Numeric Rating Scale (NRS), Oswestry Disability Index (ODI) and EuroQol-5 Dimension (EQ-5D) was recorded for each group at the time of hospital admission. Mean NRS measured weekly, mean ODI and EQ-5D scores were measured 2 weeks post-treatment, and evaluated by paired sample t test. using the Statistical Program for Social Science v. 25.0 for Windows. An independent, two-sample t test was used to test for a significant difference in the decrement of NRS, ODI and increment EQ-5D scores between groups. Results: NRS scores decreased in both groups after 1 week of treatment (electric moxibustion, from $5.13{\pm}0.79$ to $3.86{\pm}0.67$; Korean medicine alone, from $5.18{\pm}0.92$ to $4.30{\pm}0.94$; both p < 0.001). There was a significantly greater reduction in NRS score in the electric moxibustion group ($1.27{\pm}0.59$) than in the Korean medicine alone group ($0.88{\pm}0.61$; p = 0.001). After 2 weeks of treatment, EQ-5D scores increased significantly in the moxibustion group ($0.19{\pm}0.12$) compared with the Korean medicine alone group ($0.13{\pm}0.20$; p = 0.043). After 2 weeks of treatment, NRS and ODI scores decreased in both groups. EQ-5D increased in both groups. Conclusion: We suggest that electric moxibustion treatment may be effective for reducing early-stage back pain in patients with road traffic accident injuries.