• 대한수의학회지
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• 제63권1호
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• pp.7.1-7.5
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• 2023

Two 1-year-old Korean native steers in the same herd presented severe hemorrhagic diarrhea. Case 1 had severe dehydration and died after 3 days, whereas case 2 had anorexia, depression, and severe diarrhea with mucus and blood. Only case 2 was necropsied, and bovine viral diarrhea virus-2a (BVDV2a) was detected in the tissues of its alimentary tract. Gross lesions, including erosion, ulceration, and extensive hemorrhage, were observed in the digestive tract mucosa. Immunohistochemistry revealed marked positive staining for BVDV2a antigen in the large intestine. These findings are indicative of hemorrhagic disease caused by BVDV2a in a native Korean steer.

• 대한한방내과학회지
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• 제29권2호
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• pp.348-358
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• 2008

Objective : The aim of this experimental study was to investigate the anti-diarrhea effects of Jisa-tang using mice and guinea pigs. Methods : We feed Jisa-tang to mice and guinea pigs to investigate its effects for anti-diarrhea action. We observed its actions on gastrointestinal smooth muscles, on the transportability of small and large intestines, on diarrhea induced by castor oil and magnesium sulfate, and on enteropooling by castor oil and prostaglandin $E_2(PGE_2)$. Results : 1. Jisa-tang showed alleviation, depending on the density, only on the contraction of mice's gastrointestinal smooth muscles induced by histamine. 2. The transportability of the small intestine was not significantly constrained by Jisa-tang. However, the enhancement of pyridostigmine-induced transportability of he small intestine was significantly constrained in the group administered 900mg/kg of Jisa-tang (p<0.05). 3. The transportability of large intestine was significantly constrained in the group administered 1,800mg/kg of Jisa-tang. 4. Jisa-tang showed significant anti-diarrhea effects on diarrhea induced by castor oil and by $MgSO_4$ in the group administered 1,800mg/kg of Jisa-tang. 5. Significant reduction of effects of enteropooling induced by caster oil and by prostaglandin $E_2$ were observed only in the group administered 1,800mg/kg of Jisa-tang. Conclusions : We conclude that Jisa-tang has advantageous effects on drug-induced diarrhea and will contribute to the development of diarrhea treatment through further related studies.

• 한국임상수의학회지
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• 제11권2호
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• pp.585-592
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• 1994

A consecutive Jiao Chio acupuncture therapy was performed for 3 days in the 45-90 days old 11 calves of which have been shown severe watery diarrhea. The discharge of the infected calves was yellowish brown in color. Two calves of these patients were infected wi pulmonary disease as well as diarrhea. Thus, Su Qi and Fei Yu acupuncture therapy was carried out additionally after dosing with antibiotics twice for The two infected calves. Blood chemical values and serum neutralizing antibody titers were checked, and total blood cell count was also carried out to know the therapeutic effect before and after(21 days) acupuncture therapeutics. The results are as follows ; 1, The diarrhea has ceased one day after begining of the acupuncture therapy in 5 calves, and the cessation of the diarrhea in remaining calves occurred in 1 calf each on 3rd and 4th day, and 2 calves on 6th day, respectively. Two calves infected with pulmonary disease as well diarrhea were cured 8 days after the begining of the therapcutics. 2. Rotaviruses wire detected in the feces of 2 calves, and bovine diarrhea viruses were detected in the 8 calves by the test for serum neutralizing antibody titers, and bovine coronaviruses were also detected in 5 calves. Four calves of the 5 bovine coronavirus infected calves were also infected with bovine diarrhea viruses. 3. Total leucocyte number, total amount of serum protein, and amount of fibringen were slightly increased, while total erythrocyte number, and erythrocyte packed cell volume were slightly decreased. These valucs were statistically not significant. Electrolytes of Na/sup +/, K/sup +/ and Cl/sup -/ were slightly decreased but these values also were not significant. These results indicate that the acupuncture therapeutics arc significantly effective to remove the viral diarrhea in the young calves.

• Journal of Animal Science and Technology
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• 제63권4호
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• pp.864-871
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• 2021

Infectious calf diarrhea is one of the most significant diseases of neonatal calves. This study is conducted to identify the prevalence of pathogens in calf diarrhea for 2 years. A total of 544 feces samples from Korean native beef calves were obtained to investigate selected seven pathogens causing calf diarrhea: bovine rotavirus, bovine coronavirus, Cryptosporidium parvum, bovine viral diarrhea virus, Eimeria species, Escherichia coli K99, and Salmonella species. The presence of diarrhea, the number and species of detected pathogens, and the calves' ages were analyzed using various statistical methods depending on the case. Of the 544 calves, 340 calves (62.5%) had normal feces and 204 calves (37.5%) had diarrhea. The presence of pathogens was significantly associated with diarrhea (p < 0.01) and fecal scores and the number of detected pathogens showed a significant linear trend (p < 0.001). Of the 7 target pathogens, 6 were detected in samples, but only C. parvum (p = 0.001) and bovine rotavirus (p < 0.001) were found at significantly higher rates in diarrheic calves than in non-diarrheic calves. Only Eimeria spp. showed a significant linear trend between the detection rate of the pathogen and the age groups (p < 0.05).

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제1권1호
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• pp.138-143
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• 1998

저자들은 만성 설사 및 점액성 혈변을 주소로 내원한 25개월 남아에서 대장 내시경 및 조직생검, latex 응집 반응검사로 위막성 대장염 1례를 진단, 치료하였기에 보고하는 바이다.

• Journal of Microbiology and Biotechnology
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• 제28권4호
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• pp.652-662
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• 2018

Diarrhea is a global disease with a high morbidity and mortality rate in children. In this study, 25 fecal samples were collected from children under 5 years old. Seven samples had been taken from healthy children without diarrhea and marked as the healthy control group; eight samples had been sampled from children with diarrhea caused by dyspepsia and defined as the non-infectious group; and ten samples had been taken from children with diarrhea induced by intestinal infections and identified as the infectious group. We detected the microbial communities of samples by using high-throughput sequencing of 16S rRNA genes. The proportion of aerobic and facultative anaerobic microbes in samples of the infectious group was much higher than in the non-infectious group. In addition, the relative abundance of Enterococcus in the healthy control group was significantly higher than in the non-infectious group and infectious group. This can be used as a potential diagnostic biomarker for diarrhea.

• Clinical and Experimental Pediatrics
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• 제46권3호
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• pp.308-311
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• 2003

저자들은 복부 팽만과 체중감소를 주소로 내원한 신생아에서 복부 팽만이 심하여 기계적 장 폐색을 의심하여 시험적 개복술 시행하였으나, 폐색 소견 발견되지 않았고 이후 대변의 염소 이온 농도를 검사한 결과 CLD로 진단된 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• 사상체질의학회지
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• 제22권2호
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• pp.16-27
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• 2010

1. Backgrounds: There are a lack of comprehensive study on Taeeumin Exterior Heat syndrome diarrhea(表熱證泄瀉). Thus, The author examines the content of various literatures related to Tae-eumin Exterior Heat syndrome diarrhea. 2. Methods: Literature examination is used Lee, Je-ma's writings and Sasang Constitutional Medical doctor's writings. Syndrome examination is used Tae-eumin's study on Syndrome of DonguisusebowonGaboGu-bon("咸山沙村東醫壽世保元甲午舊本") and Donguisusebowon("東醫壽世保元") and treatises of the academic world. 3. Results: and Conclusions: 1) "Profuse sweating and reddish and difficult urination"(汗多而小便赤澁) is regard as Taeeumin Interior Febrile Disease(裏熱病). 2) There is no possibility of a misprint about Taeeumin Exterior Heat syndrome diarrhea. Taeeumin Exterior Heat syndrome diarrhea is engaged in both the Exterior and Interior(表裏俱病). 3) It is difficult to prescribe GalgeunHaegi-Tang(葛根解肌湯) instead of Galgeunnabokja-Tang(葛根蘿葍子湯). 4) Tae-eumin Exterior Heat syndrome diarrhea is formed in the early period and absorbed into Donguisusebowon ("東醫壽世保元") in the latter period. "Profuse sweating and reddish and difficult urination" is estimated to be added in the latter period.

• Journal of Korean Biological Nursing Science
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• 제10권2호
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• pp.105-112
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• 2008

Purpose: The purpose of this study was to investigate the difference in the incidence of diarrhea among the subjects given hypertonic and isotonic nutrients to the nasogastric tube feeding patients in the a critical care setting. Methods: This study is aquasi-experimental study with a pre & post-test design. The sample size of 40 was calculated based on Cohen's formula (1988). The total of 40 subjects who signed the informed consent were randomly selected and divided evenly into two groups, experimental and control group. Results: There are no significant differences between the two groups in homogeneity test (sex, age, albumin level, the use of antibiotics, antacid, and $H_2$ blocker). However, the frequencies of occurrence in diarrhea according to the density of nutrients formulation indicated a statistical difference at the level of .005 (p=.001): diarrhea occurred in four of 20 (20%) of the experiment group, but 14 (70%) of the control group. Also the onset date of diarrhea in the experiment group is later than that of the control group. Conclusion: The research findings suggest that we should begin with low density nutrients for nasogastric tube feeding, and increase its density gradually to decrease diarrhea incidence in the critical care setting.

• 대한한의학방제학회지
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• 제24권3호
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• pp.213-224
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• 2016

Objectives : The purpose of this study is to investigate the effect of Leejung-tang plus Oryung-san Gamibang on functional diarrhea.Method : We treated a 72-year-old male who had severe watery diarrhea and bowel sounds. The patient was treated with Korean medicine including Oryung-san Gamibang from March 31, 2016 to May 23, 2016. Defecation frequency, Bristol stool scale, Bowel sound, Patient's condition were measured.Result : After oriental medical treatment, clinical symptoms of functional diarrhea (defecation frequency, stool form, bowel sounds) were recoverd normally.Conclusions : Leejung-tang plus Oryeong-san Gamibang effects on the functional diarrhea of a patient diagnosed as Deficiency Cold (虛寒). This case study shows that Oryeong-san Gamibang is clinically effective for functional diarrhea. So that, it is helpful in decreasing the symptoms of a patient and in improving quality of life.