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Hemorrhagic disease caused by bovine viral diarrhea virus-2a in Korean Indigenous Cattle: case reports

  • Hyung-Chul Cho (Department of Animal Science and Biotechnology, College of Ecology and Environmental Science, Kyungpook National University) ;
  • Byoung-Soo Kim (Yeongkwang Veterinary Clinic) ;
  • Dong-Hun Jang (Department of Animal Science and Biotechnology, College of Ecology and Environmental Science, Kyungpook National University) ;
  • Kyung-Hyun Lee (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Kyoung-Seong Choi (Department of Animal Science and Biotechnology, College of Ecology and Environmental Science, Kyungpook National University)
  • Received : 2023.01.27
  • Accepted : 2023.03.24
  • Published : 2023.03.31

Abstract

Two 1-year-old Korean native steers in the same herd presented severe hemorrhagic diarrhea. Case 1 had severe dehydration and died after 3 days, whereas case 2 had anorexia, depression, and severe diarrhea with mucus and blood. Only case 2 was necropsied, and bovine viral diarrhea virus-2a (BVDV2a) was detected in the tissues of its alimentary tract. Gross lesions, including erosion, ulceration, and extensive hemorrhage, were observed in the digestive tract mucosa. Immunohistochemistry revealed marked positive staining for BVDV2a antigen in the large intestine. These findings are indicative of hemorrhagic disease caused by BVDV2a in a native Korean steer.

Keywords

Acknowledgement

This research was funded by the Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, and Forestry (IPET) (Grant No. 122017-02-1-HD020).

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