• Title/Summary/Keyword: diagnostic significance

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The Development of pulse Diagnostic Apparatus enable to gain multi-information and it's Clinical Significance (다정보(多情報) 획득(獲得)을 위한 맥진기 개발과 임상적 의의)

  • Park, Y.B.;Lee, H.J.;Huh, W
    • The Journal of Korean Medicine
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    • v.16 no.1 s.29
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    • pp.499-504
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    • 1995
  • Recently, there are deep and much concerns about the objective assessment of diagnosis in Oriental Medicine. Among them, pulse diagnostics is used for the quantitative device of diagnosis. The objective research of pulse diagnosis were mainly conducted by pulse wave. So it is important to gain multi-information for the quantification of pulse diagnosis. We report the development of pulse diagnostic apparatus enable to gain the multi-information, detect the pressure pulse wave in conku(寸口) area and obtain the gradient curve and original pulse wave simultaneously, and consider the pulse wave with the traditional pulse diagnosis at the same time.

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Vascular Dementia (혈관성 치매)

  • Kim, Tae Woo;Kwak, Kyung Phil
    • Korean Journal of Biological Psychiatry
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    • v.23 no.3
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    • pp.80-88
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    • 2016
  • Vascular dementia is a very frequent form of dementia. Debates over classification and diagnostic criteria, and controversy over identifiable treatment targets will continue until distinct pathophysiological mechanism of vascular dementia is found. Clinical diagnostic criteria are sufficiently strong to be useful for clinical trials, but need further refinement. Cognitive changes in vascular dementia are more variable than other disorders, and are dependent on the vascular pathology. Accurate diagnosis of vascular dementia is known to need the presence of reliable cerebrovascular disease on brain imaging. Although it seems obvious that cerebrovascular disease causes pathological damage and impaired cognition, it is very difficult to find the accurate contribution of cerebrovascular pathology to cognitive decline. Most studies have shown a small but significant benefit of cholinesterase inhibitors on cognition, the significance of this effect has been slight and benefits on global functioning, activities of daily living, and behaviour have not been consistently reported. Management of vascular dementia should focus on identifying and managing vascular risk factors.

Clinical Application of $^{18}F-FDG$ PET in Brain Tumors (뇌종양에서의 $^{18}F-FDG$ PET의 임상 이용)

  • Hong, Il-Ki;Kim, Jae-Seung
    • Nuclear Medicine and Molecular Imaging
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    • v.42 no.sup1
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    • pp.1-5
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    • 2008
  • Primary brain tumor accounts for 1.4% of entire cancer. For males between the ages of 15 and 34 years, central nervous system tumors account for the leading cause of cancer death. $^{18}F-FDG$ PET has been reported that it can provide important diagnostic information relating to tumor grading and differentiation from non- tumorous condition. In addition, the degree of FDG metabolism carries prognostic significance. By mapping the metabolic pattern of heterogeneous tumors, $^{18}F-FDG$ PET can aid in targeting for stereotactic biopsy by selecting the subregions within the tumor that are most hypermetabolic and potentially have the highest grade. According to clinical research data, FOG PET is expected to be a helpful diagnostic tool in the management of brain tumors.

The Significance of 3-Dimensional Imaging in Tracheal Stenosis (기관협착증에서 3차원적 영상 진단의 의의)

  • 정동학;봉정표;이운우;노정래;성기준
    • Korean Journal of Bronchoesophagology
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    • v.1 no.1
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    • pp.82-93
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    • 1995
  • Three-dimensional reconstruction of computed tomographic image(3D CT) is a well-established imaging modality which has been investigated in various clinical settings. It is commonly performed in case of congenital or developmental abnormalities, and traumatic fracture of skull and face that requires reconstruction of osseous structure. However reporting the 3D CT in laryngeal or tracheal stenosis is rare and its results are obscure. The authors performed 3D CT in six cases of tracheal stenosis and found diagnostic value of 3D CT. A Comparision of diagnostic information obtained from plain X-ray, 2D CT and 3D CT has performed in total six cases of tracheal stenosis. Surgical treatment of the tracheal stenosis was following in these cases : tracheal end to end anastomosis In 1 case, laryngotracheal end to end anastomosis in 2 cases. 3D CT information was compared with operative finding. In two of six cases, satisfactory information was not obtained from 3D CT in evaluating an exact stenosis of trachea. Future, it will be helped in evaluating of tracheal stenosis by 3D CT.

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Modality-Specific Working Memory Systems Verified by Clinical Working Memory Tests

  • Park, Eun-Hee;Jon, Duk-In
    • Clinical Psychopharmacology and Neuroscience
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    • v.16 no.4
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    • pp.489-493
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    • 2018
  • Objective: This study was to identify whether working memory (WM) can be clearly subdivided according to auditory and visual modality. To do this, we administered the most recent and universal clinical WM measures in a mixed psychiatric sample. Methods: A total of 115 patients were diagnosed on the basis of DSM-IV diagnostic criteria and with MINI-Plus 5.0, a structured diagnostic interview. WM subtests of Korean version of Wechsler Adult Intelligence Scale-IV and Korean version of Wechsler Memory Scale-IV were administered to assess WM. Confirmatory factor analysis (CFA) was used to observe whether WM measures fit better to a one-factor or two-factor model. Results: CFA results demonstrated that a two factor model fits the data better than one-factor model as expected. Conclusion: Our study supports a modality model of WM, or the existence of modality-specific WM systems, and thus poses a clinical significance of assessing both auditory and visual WM tests.

Application of Laboratory Medicine in the Field of Oral Medicine

  • Moon-Jong Kim
    • Journal of Oral Medicine and Pain
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    • v.47 no.4
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    • pp.167-173
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    • 2022
  • Various diseases of the orofacial region that are treated in the field of oral medicine not only are associated with local factors but may also be affected by systemic factors. Knowledge about laboratory medicine is needed to identify the systemic factors that can influence these diseases. Therefore, oral medicine specialists should be able to use diagnostic tests of laboratory medicine and interpret the results in diagnosing and treating diseases in the field of oral medicine. The aim of this article is to examine the diagnostic tests used in laboratory medicine that might be applied to assess the systemic aspect of diseases in the field of oral medicine and to interpret the significance of the findings.

A hybrid structural health monitoring technique for detection of subtle structural damage

  • Krishansamy, Lakshmi;Arumulla, Rama Mohan Rao
    • Smart Structures and Systems
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    • v.22 no.5
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    • pp.587-609
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    • 2018
  • There is greater significance in identifying the incipient damages in structures at the time of their initiation as timely rectification of these minor incipient cracks can save huge maintenance cost. However, the change in the global dynamic characteristics of a structure due to these subtle damages are insignificant enough to detect using the majority of the current damage diagnostic techniques. Keeping this in view, we propose a hybrid damage diagnostic technique for detection of minor incipient damages in the structures. In the proposed automated hybrid algorithm, the raw dynamic signatures obtained from the structure are decomposed to uni-modal signals and the dynamic signature are reconstructed by identifying and combining only the uni-modal signals altered by the minor incipient damage. We use these reconstructed signals for damage diagnostics using ARMAX model. Numerical simulation studies are carried out to investigate and evaluate the proposed hybrid damage diagnostic algorithm and their capability in identifying minor/incipient damage with noisy measurements. Finally, experimental studies on a beam are also presented to compliment the numerical simulations in order to demonstrate the practical application of the proposed algorithm.

Cytologic Feature of Papillary Carcinoma of the Thyroid (세침흡인 검사로 진단된 갑상선 유두상 암종의 세포학적 소견)

  • Park, Jeong-Hee;Chang, Hee-Jin;Kang, Kyung-Ha;Sohn, Jin-Hee;Suh, Jung-Il
    • The Korean Journal of Cytopathology
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    • v.2 no.2
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    • pp.111-118
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    • 1991
  • Fine needle aspiration biopsy cytology (FNA) is an important diagnostic tool in the management of thyroid nodule. Especially, papillary carcinoma of the thyroid has distinct morphologic features that allow a definite cytologic diagnosis with high degree of accuracy. We examined the characteristic cytologic features of 57 cases of papillary carcinoma of the thyroid, and their frequency and diagnostic significance were evaluated. The results obtained are summerized as follows; 1. In pattern of cellular arrangement, papillary structure with or without stroma is predominant feature (96%). 2. In individual cell morphology, grooved nuclei (95%), intranuclear cytoplasmic invagination (89%) and nuclear lobulation (74%) are most frequent and important cytologic findings. 3. Chromatin pattern is usually fine. Coarse chromatin is infrequent finding (37%). Nucleoli are inconspicuous. Cytoplasm us plump and distinctly eosinophilic. 4. Psammoma bodies are identified only in 4 cases (7%), but they are considered as helpful diagnostic features. 5. There are other associated findings including multinucleated giant cells (51%), macrophages (37%) and cystic degeneration (16%).

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Incidental occurrence of an unusually large mastoid foramen on cone-beam computed tomography and review of the literature

  • Syed, Ali Z.;Sin, Cleo;Rios, Raquel;Mupparapu, Mel
    • Imaging Science in Dentistry
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    • v.46 no.1
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    • pp.39-45
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    • 2016
  • The incidental finding of an enlarged mastoid foramen on the right posterior mastoid region of temporal bone is reported, together with a discussion of its clinical significance. A 67-year-old female underwent the pre-implant assessment of a maxillary left edentulous region. A cone-beam computed tomographic (CBCT) image was acquired and referred for consultation. Axial CBCT slices revealed a unilateral, well-defined, noncorticated, low-attenuation, transosseous defect posterior to the mastoid air cells in the right temporal bone. The borders of the osseous defect were smooth and continuous. No other radiographic signs suggestive of erosion or sclerosis were noted in the vicinity. The density within the defect was homogenous and consistent with a foramen and/or soft tissue. The patient's history and physical examination revealed no significant medical issues, and she was referred to a neuroradiologist for a second opinion. The diagnosis of an enlarged mastoid foramen was made and the patient was reassured.

Evaluation of Thermography in the Diagnosis of Carpal Tunnel Syndrome : Comparative Study between Patient and Control Groups

  • Hong, Yong-Pyo;Ryu, Kyeong-Sik;Cho, Byung-Moon;Oh, Sae-Moon;Park, Se-Hyuck
    • Journal of Korean Neurosurgical Society
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    • v.39 no.6
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    • pp.423-426
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    • 2006
  • Objective : There is still debate about the diagnostic efficacy of digital infrared thermographic imaging[DITI], nevertheless, it has been used for the diagnosis of carpal tunnel syndrome[CTS]. We performed comparative study between patient and control groups to investigate the diagnostic value of DITI in CTS. Methods : We studied 27 patients with electrodiagnostically-proven CTS and 18 symptom-free volunteers as a control. We measured thermal difference on DITI in the corresponding regions of the hands and forearms. We statistically analyzed the thermal data using a t-test. Results : The average thermal difference in the diagnosed patient group ranged from $0.0303^{\circ}C$ to $0.2856^{\circ}C$, while that in control group ranged from $0.0611^{\circ}C$ to $0.2878^{\circ}C$. In the CTS patient group, thermal difference between each 2nd finger was higher than that of other regions. However, there was no statistical significance between patient and control groups. Conclusion : We found that the diagnostic value of DITI in CTS was not sufficient. There should be a reconsideration of the usefulness of DITI in CTS.