• Title/Summary/Keyword: diabetes.

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The Mediating Effect of Self-efficacy in the Relationship between Diabetes Knowledge and Health Promoting Behaviors: Focus on Gender Differentiation (지역사회 중년의 당뇨병 지식과 건강증진행위 사이의 자기효능감의 매개효과 : 성별차이를 중심으로)

  • Hong, Eunyoung
    • The Journal of Korean Academic Society of Nursing Education
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    • v.21 no.4
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    • pp.509-517
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    • 2015
  • Purpose: This study examined diabetes knowledge, self-efficacy, and health promoting behaviors, and investigated factors affecting health-promoting behaviors of middle-aged people. Methods: From August to September 2014, a convenience sample of 264 subjects was recruited from B city and G province. The data analysis was done by ${\chi}^2$ test, t-test, Pearson's correlation coefficient, and stepwise multiple regression. Results: Diabetes knowledge was $11.3{\pm}3.63$ in men and $12.7{\pm}3.74$ in women. The average levels of self-efficacy and health promoting behaviors of subjects were similar with other middle-aged individuals. Diabetes knowledge, self-efficacy, and health promoting behaviors had a positive correlation with each other in both men and women. To test the mediating effect of self-efficacy in the relationship between diabetes knowledge and health promoting behaviors, a Sobel test was performed and Z-scores of 3.698(p<.001) in men and 2.748(p=.006) in women were obtained. Conclusion: Diabetes prevention education is recommended for the middle-aged community. When developing diabetes prevention program for middle-aged people, such programs should consider self-efficacy, especially in women.

Zinc in Pancreatic Islet Biology, Insulin Sensitivity, and Diabetes

  • Maret, Wolfgang
    • Preventive Nutrition and Food Science
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    • v.22 no.1
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    • pp.1-8
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    • 2017
  • About 20 chemical elements are nutritionally essential for humans with defined molecular functions. Several essential and nonessential biometals are either functional nutrients with antidiabetic actions or can be diabetogenic. A key question remains whether changes in the metabolism of biometals and biominerals are a consequence of diabetes or are involved in its etiology. Exploration of the roles of zinc (Zn) in this regard is most revealing because 80 years of scientific discoveries link zinc and diabetes. In pancreatic ${\beta}$- and ${\alpha}$-cells, zinc has specific functions in the biochemistry of insulin and glucagon. When zinc ions are secreted during vesicular exocytosis, they have autocrine, paracrine, and endocrine roles. The membrane protein ZnT8 transports zinc ions into the insulin and glucagon granules. ZnT8 has a risk allele that predisposes the majority of humans to developing diabetes. In target tissues, increased availability of zinc enhances the insulin response by inhibiting protein tyrosine phosphatase 1B, which controls the phosphorylation state of the insulin receptor and hence downstream signalling. Inherited diseases of zinc metabolism, environmental exposures that interfere with the control of cellular zinc homeostasis, and nutritional or conditioned zinc deficiency influence the pathobiochemistry of diabetes. Accepting the view that zinc is one of the many factors in multiple gene-environment interactions that cause the functional demise of ${\beta}$-cells generates an immense potential for treating and perhaps preventing diabetes. Personalized nutrition, bioactive food, and pharmaceuticals targeting the control of cellular zinc in precision medicine are among the possible interventions.

Community based strategies and directions for the management of hypertension and diabetes (고혈압 및 당뇨병 관리를 위한 지역사회중심의 접근전략과 발전방향)

  • Lee, Soon Young
    • Korean Journal of Health Education and Promotion
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    • v.33 no.4
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    • pp.67-77
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    • 2016
  • Objectives: The study was to propose strategies and directions how to manage the hypertension and diabetes in communities. Methods: The survey data from 606 patients with hypertension or diabetes based on Community Health Survey, 2013 were analyzed and the hypertension and diabetes projects in communities for last 10 years were reviewed. Results: The patients visiting the primary clinics had statistically significant lower rates than those of teaching hospitals in physician's recommendation experience, perception level of attention from doctors, self-efficacy and health habit practice level. Since the Hypertension and diabetes registration and management system in 2007, there have been several trials for management of hypertension and diabetes such as Chronic diseases management system on the primary clinics, Community based primary medical care pilot projects, Post-national health screening management, and Pilot project on reimbursement for chronic diseases care services. Conclusions: The upmost urgent task might be to have a support system for patients' self care affiliated with primary clinics. To achieve it, it is necessary to expand the current Hypertension and diabetes registration and management system into nation and to find a way to attract the active participation from primary clinics.

A Metabolomic Approach to Understanding the Metabolic Link between Obesity and Diabetes

  • Park, Seokjae;Sadanala, Krishna Chaitanya;Kim, Eun-Kyoung
    • Molecules and Cells
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    • v.38 no.7
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    • pp.587-596
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    • 2015
  • Obesity and diabetes arise from an intricate interplay between both genetic and environmental factors. It is well recognized that obesity plays an important role in the development of insulin resistance and diabetes. Yet, the exact mechanism of the connection between obesity and diabetes is still not completely understood. Metabolomics is an analytical approach that aims to detect and quantify small metabolites. Recently, there has been an increased interest in the application of metabolomics to the identification of disease biomarkers, with a number of well-known biomarkers identified. Metabolomics is a potent approach to unravel the intricate relationships between metabolism, obesity and progression to diabetes and, at the same time, has potential as a clinical tool for risk evaluation and monitoring of disease. Moreover, metabolomics applications have revealed alterations in the levels of metabolites related to obesity-associated diabetes. This review focuses on the part that metabolomics has played in elucidating the roles of metabolites in the regulation of systemic metabolism relevant to obesity and diabetes. It also explains the possible metabolic relation and association between the two diseases. The metabolites with altered profiles in individual disorders and those that are specifically and similarly altered in both disorders are classified, categorized and summarized.

The Validity and Reliability of a Korean Version of the Summary of Diabetes Self-Care Activities Questionnaire for Older Patients with Type 2 Diabetes (제2형 당뇨노인을 대상으로 한 당뇨 자가 관리 측정도구(The Summary of Diabetes Self-Care Activities Questionnaire, SDSCA) 한국어 버전의 타당도와 신뢰도 검증)

  • Chang, Sun-Ju;Song, Mi-Soon
    • Korean Journal of Adult Nursing
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    • v.21 no.2
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    • pp.235-244
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    • 2009
  • Purpose: This research was carried out to evaluate the validity and reliability of the Korean version of the Summary of Diabetes Self-Care Activities Questionnaire (SDSCA) for Korean older adults with type 2 diabetes. Methods: Translation and back-translation were performed to develop the Korean version of the SDSCA. Then the Korean version SDSCA was applied to a sample of 112 older adults who had participated in diabetes self management education in Seoul. The internal consistency and the test-retest reliability were examined to test the reliability. Factor analysis was used to examine the construct validity. Results: The internal consistency measured with Cronbach's alpha was .77 and the total test-retest reliability was .68 with items ranging from .21 to 1.00. As the result of the factor analysis, six factors -foot care, diet, exercise, blood sugar test, medication, and smoking- were revealed as the original instrument subcategories. These six factors explained 81.17% of total variance. Conclusion: The reliability and validity of the Korean version SDSCA Questionnaire was supported for use in older patients with type 2 diabetes in Korea.

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Factors Influencing the Level of Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus (제2형 당뇨병 환자의 당뇨병성망막증 정도에 영향을 미치는 요인)

  • Chang, Eun Ae;Shin, Yun Hee
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.23 no.3
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    • pp.300-309
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    • 2016
  • Purpose: This study was a descriptive survey research to identify whether characteristics of patients with type 2 diabetes mellitus, their knowledge about diabetes, and self-care behavior impacted on the level of diabetic retinopathy. Methods: Participants were 133 patients who had type 2 diabetes mellitus and were being seen at a hospital in Korea. The scale for knowledge about diabetes had 24 items, the scale for self-care behavior, 20 items, and the level of diabetic retinopathy was classified according to the international clinical diabetic retinopathy severity measurement standards. Results: The influence of the independent variables on the level of diabetic retinopathy showed that age, job, time since onset of Diabetes Mellitus, regular ophthalmologic examinations, and systolic blood pressure were identified as factors affecting the level of diabetic retinopathy. The explanation power of this regression model was 23.0% and it was statistically significant (F=5.42, p<.001). Conclusion: Early education about occurrence of diabetes related diseases, specifically diabetic retinopathy should be provided for patients from younger ages. Moreover, for disease management, social support is needed from co-workers and friends. Efforts to encouraged prevention and delay of diabetic retinopathy should include control of blood sugar and blood pressure.

A study on relationship between HbA1c, WHR, WTR and compliance in elderly diabetes mellitus patients (노인 당뇨병 환자의 당화혈색소, 허리/엉덩이둘레, 허리/허벅지둘레 및 치료지시이행과의 관계)

  • Yoo, Yong Kwon;Song, Min Sun
    • Journal of Korean Academic Society of Home Health Care Nursing
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    • v.22 no.1
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    • pp.14-21
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    • 2015
  • Purpose: The purpose of this study was to identify relationships between HbA1c (Glycosylated Hemoglobin), WHR (Waist hip ratio), WTR (Waist thigh ratio) and compliance in elderly diabetes mellitus patients aged 65 years or over. Method: We conducted a survey and measured HbA1c, WHR, WTR in a total of 180 elderly patients with diabetes from 5 May 2014 to 30 May 2014. The data were analyzed by t-test, ANOVA, and Pearson's Correlation Coefficient using the SPSS program. Results: There were no significant differences in diabetes-related characteristics for HbA1c, WHR and WTR. However, patients with a family history had low compliance scores (p=.004). Furthermore, patients who visited the hospital regularly had higher compliance scores than patients who visited hospital when they were sick (p<.001). Patients with diabetic complications had low treatment compliance scores (p=.001). In addition, WHR and WTR (r=0.47, p<.001). and WHR and compliance (r=0.15, p=.045) showed positive correlation. Conclusion: For elderly diabetes mellitus patients, diabetes-related characteristics and compliance were highly related, so it is necessary to improve compliance for managing diabetes mellitus.

Prevalence Rates and Risk Factors of Non-Insulin-Dependent Diabetes Mellitus in Minorities in the United States

  • Sohn, Ae-Ree
    • Korean Journal of Health Education and Promotion
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    • v.2 no.1
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    • pp.97-114
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    • 2000
  • Minority populations in the United States have a higher prevalence of non-insulin-dependent diabetes mellitus (NIDDM) and more persons die of the disease than white persons. This study was to review and compare risk factors and prevalence rates of NIDDM in African Americans, Hispanic s, Korean Americans and Native Americans in the United States. The risk factors of NIDDM, including family history of diabetes, obesity, physical inactivity, diet and age, were reviewed in the minority populations. Risk factors such as obesity, physical inactivity and family history of diabetes occurred to a greater extent in some minority populations than in the white population. Diabetes should be treated as a public health problem for minority populations. Due to the increase of older populations and the increased prevalence of obesity and sedentariness, NIDDM in minorities is nearing epidemic proportions. Good diet and regular exercise can reduce the incidence of NIDDM but an understanding of the cultural aspects of diabetes is imperative in order to provide adequate community health education programs because those programs involve diet and behavior changes, characteristics that are often culturally determined. In summary, it is important to plan a community health education program targeted on NIDDM in a culturally adapted manner that will be received with both comprehension and acceptability. In particular, the program for high-risk populations should be stressed so to prevent diabetes. Preventive approaches to diabetes should be considered because they can be both therapeutic and cost effective.

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The Validity and Reliability of a Korean Version of the Diabetes Self-Care Barriers Assessment Scale for Older Adults with Type 2 Diabetes (제2형 당뇨노인을 대상으로 한 당뇨 자가관리 방해요인 사정도구(DSCB-OA) 한국어 버전의 타당도와 신뢰도 검증)

  • Chang, Sun-Ju;Kang, Kyung-Ja
    • Journal of muscle and joint health
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    • v.17 no.2
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    • pp.183-191
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    • 2010
  • Purpose: The purpose of this study was to test the validity and reliability of the Diabetes Self-Care Barriers Assessment Scaler for Older Adults (DSCB-OA) in Korean older adults with type 2 diabetes. Method: To develop Korean version DSCB-OA used translation and back-translation method. Then, Korean version DSCB-OA was analyzed using data of 278 older adults with type 2 diabetes. Cronbach's alpha coefficient, item to total correlation and test-retest reliability was used for the reliability test, and factor analysis was used for the construct validity. Results: Cronabach's alpha of the DSCB-OA was.77, and item to total correlation coefficient ranged from -.13 to.56. The results of factor analysis showed DSCB-OA consisted of four factors(diet, exercise, blood sugar test, treatment) which explained 62.8% of total variance. Conclusion: The Diabetes Self-Care Barriers Assessment Scaler for Older Adults (DSCB-OA) was confirmed helpful tool for Korean older adults with type 2 diabetes.

Socioeconomic Predictors of Diabetes Mortality in Japan: An Ecological Study Using Municipality-specific Data

  • Okui, Tasuku
    • Journal of Preventive Medicine and Public Health
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    • v.54 no.5
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    • pp.352-359
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    • 2021
  • Objectives: The aim of this study was to examine the geographic distribution of diabetes mortality in Japan and identify socioeconomic factors affecting differences in municipality-specific diabetes mortality. Methods: Diabetes mortality data by year and municipality from 2013 to 2017 were extracted from Japanese Vital Statistics, and the socioeconomic characteristics of municipalities were obtained from government statistics. We calculated the standardized mortality ratio (SMR) of diabetes for each municipality using the empirical Bayes method and represented geographic differences in SMRs in a map of Japan. Multiple linear regression was conducted to identify the socioeconomic factors affecting differences in SMR. Statistically significant socioeconomic factors were further assessed by calculating the relative risk of mortality of quintiles of municipalities classified according to the degree of each socioeconomic factor using Poisson regression analysis. Results: The geographic distribution of diabetes mortality differed by gender. Of the municipality-specific socioeconomic factors, high rates of single-person households and unemployment and a high number of hospital beds were associated with a high SMR for men. High rates of fatherless households and blue-collar workers were associated with a high SMR for women, while high taxable income per-capita income and total population were associated with low SMR for women. Quintile analysis revealed a complex relationship between taxable income and mortality for women. The mortality risk of quintiles with the highest and lowest taxable per-capita income was significantly lower than that of the middle-income quintile. Conclusions: Socioeconomic factors of municipalities in Japan were found to affect geographic differences in diabetes mortality.