• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제31권2호
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• pp.137-142
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• 2005

To analyze the developmental changes in soma diameters of digastric motoneurons, wheat-germ agglutinin conjugated horseradish peroxidase (WGA-HRP) was injected into the digastric muscle and visualized the retrogradely HRP-labeled motoneurons through tungstate/tetramethylbenzidine (TMB) and following diaminobenzidine (DAB) reactions. The results obtained from Sprague-Dawley rats at postnatal days 1 (P1), 10 (P10) and 30 (P30) indicated as follows: firstly, soma diameters of digastric motoneurons showed unimodal distribution in all postnatal days examined; secondly, the period of P1 to P10 (period 1) showed about 2 times faster growth rate than that of P10 to P30 (period 2); thirdly, the smallest soma examined in each postnatal day exhibited slower growth rate with that of the largest one (increase ratio in soma diameters from P1 to P30, smallest vs. largest = 1.62 : 1.93); Finally, relative growth rates a day showed again that period 1 had faster growth rate than that of period 2. Consequently, developmental changes in soma diameters of digastric motoneurons resulted in very different growth rates between both periods. This implies that the growth of the soma is almost completing within P10 and thereafter growing slowly. The period 1 and 2 are corresponding to sucking and sucking/masticatory period, respectively. Therefore present study providing morphological changes in soma diameters of digastric motoneurons suggests that both periods and their different growth rates of the motoneurons in each period may closely be related with each other.

• 한국응용곤충학회지
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• 제52권1호
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• pp.5-12
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• 2013

비트의 주요 해충인 흰띠명나방을 9개의 다른 온도조건(15.0, 17.5, 20.0, 22.5, 25.0, 27.5, 30.0, 32.5 및 $35.0^{\circ}C$), 상대습도 $65{\pm}5%$, 광조건 16L:8D에서 발육특성을 조사한 결과, 알에서 성충 우화 전까지의 발육기간은 $17.5^{\circ}C$에서 51.0일로 가장 길었고, $35^{\circ}C$에서 14.6일로 가장 짧게 조사되었다. 온도와 발육율의 관계를 직선회귀에 의해 분석한 결과, 결정계수($R^2$) 값이 0.87 이상으로 나타났으며, 온도에 따른 발육은 직선회귀에 부합되었다. 알부터 성충 우화 전까지의 발육영점온도와 유효적산온도는 $10.4^{\circ}C$와 384.7일도를 나타내었다. 각 태별 발육모형은 $R^2$값이 0.97~0.99로 비선형회귀식에 잘 부합되었다. 각 태별 발육누적분포와 발육기간에 대한 평균 발육기간으로 나눈 값을 Weibull 함수에 적용한 결과 $r^2$값이 0.63~0.87이었다.

• 대한감각통합치료학회지
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• 제19권2호
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• pp.36-45
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• 2021

목적 : 본 연구는 발달지연의 아동을 대상으로 과제지향의 중재를 사용하여 시-운동 협응과 소운동 협응 기능의 변화를 알아보고자 하였다. 연구방법 : 연구대상은 6세의 여아 1명이었다. 아동은 진단은 받지 않았으나 전반적인 기능에 발달지연을 보였다. 연구기간은 2021년 2월 5일부터 6월 4일까지이었고, 연구 설계는 단일대상연구 A-B를 사용하였다. 기초선 A는 초기 3회기로 아동의 기능 파악을 위해 초기평가를 하였다. 중재기 B는 12회기로 과제지향의 중재(task-oriented intervention)를 사용하였다. 기초선과 중재기에 동일하게 아동의 시-운동 협응 기능을 측정하기 위해 한국판 시지각발달검사 3판의 타원그리기를 실시하였고, 소운동 협응 기능을 측정하기 위해 Clinical Observation of Motor and Postural Skills(COMPS)의 손가락-코 짚기를 실시하였다. 회기별 변화도는 그림으로 제시하였다. 결과 : 한국판 시지각발달검사 3판의 타원그리기의 기초선 평균은 23점이었고, 중재기 평균은 39.66점으로 기초선에 비해 중재기의 평균이 16점 이상 향상되었다. COMPS의 손가락-코 짚기의 기초선 평균은 0점이었고, 중재기 평균은 5.08점으로 기초선에 비해 중재기의 평균이 5점 이상 향상되었다. 결론 : 취학 전의 발달지연아동에게 과제지향의 중재는 아동의 학습에 바탕이 되는 시-운동 협응과 소운동 협응 기능에 긍정적인 영향을 미치는 것으로 보인다.

• 복식
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• 제45권
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• pp.41-54
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• 1999

The purpose of this thesis is to trace the development of cotton Early Chosun Period by examining the historical literary sources : such as production of cotton various uses of cotton trade with other countries The developement process of cotton fabrics during this period can be divided into three stages. The first stage which can be discribed as a settling period lasted 27 years from A.D. 1392 to 1418. In this stage cotton fabrics were just about to be used as fabrics for popular clothing. The second stage which can be discribed as a developmental period lasted 50 years from A. D.1418 to 1468. In this stage cotton fabrics were mainly produced in the southern parts of the country which are Kyungasng-Do, Choongcheng-Do and Jeunla-Do. And cotton fabrics were used not only by the common people but also by the royal family. The third stage, that is the last one was an extensive period and lasted from A.D.1469 to 1592. In this stage as the demand for cotton fabrics greatly increased the production from southern parts of the country fell in short of the supply needed. Therefore the production was extended to the northwestern parts. In addition cotton fabrics finally came to be used as money to value the goods.

• 한국의류학회지
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• 제32권11호
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• pp.1680-1691
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• 2008

This study examines how the development and value of dresses shown in MBC historical dramas have changed with the overall change of the dramas. As for the research method, the second data analysis was done with literature study which was supplemented with interviews with the wardrobe team of MBC production design center. Historical dramas produced by MBC have gone through the developmental period, legitimate historical drama-oriented period, stagnant period, and historical dramas-modernized period. The value of costume in each period is as follows: Costume in the developmental period is considered only as part of drama setting. During legitimate historical drama-oriented period, it carries value as educational data and historical replica produced by historical research. Production design including costume obtains its own value in the stagnant period although the production of historical dramas decreases dramatically. And lastly, in the historical dramas-modernized period, costume starts to have commercial value as cultural contents. Historical drama costume may contain important value in terms of education and history, even though there has been controversy on TV historical dramas' role: they should focus on reproducing historical facts or they should support writers' creativity.

• 동서간호학연구지
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• 제7권1호
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• pp.94-104
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• 2002

The purposes of this study were to identify the relationship between parent and child with chronic illness and developmental disability, and to review the strategy for improvement of their relationship. The effects of chronic illness and developmental disability is that the child has delayed growth and development, and his(her) parent has sadness, guilty feeling, anxiety, grief, disappointment, low self-esteem, anger and resentment. Chronic illness and developmental disability also have a negative effect to the parental marital relationship. The reaction of parent and child varies in age of onset, a developmental transition period, crisis and parent-child relationship. Through this study, I propose that parent-child relationship could be improved by touch, communication between them and education for parents.

• 한국실내디자인학회논문집
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• 제23권3호
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• pp.3-10
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• 2014

School age is the period when forms the most of physical, spiritual and behavioral developmental characteristics. And those are kept for lifetime. Since each of developmental characteristics is created through the interaction with physical environment, the learning space which is children's main playground should be designed as healing environment. Therefor, the purpose of this research is to find the healing environmental elements for learning space that help school children's developmental characteristics. For that, we researched the physical, spiritual and behavioral developmental characteristics of school children. And we found the healing environmental characteristics for learning space along with each developmental characteristics, by the analysis of Herman Hertzberger's elementary schools' classroom environment.

• Molecules and Cells
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• 제45권10호
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• pp.685-691
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• 2022

Early-life environmental factors can have persistent effects on physiological functions by altering developmental procedures in various organisms. Recent experimental and epidemiological studies now further support the idea that developmental programming is also present in mammals, including humans, influencing long-term health. Although the mechanism of programming is still largely under investigation, the role of endocrine glucocorticoids in developmental programming is gaining interest. Studies found that perinatal glucocorticoids have a persistent effect on multiple functions of the body, including metabolic, behavioral, and immune functions, in adulthood. Several mechanisms have been proposed to play a role in long-term programming. In this review, recent findings on this topic are summarized and the potential biological rationale behind this phenomenon is discussed.

• International Journal of Aeronautical and Space Sciences
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• 제11권4호
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• pp.313-318
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• 2010

The power plant system of a tilt rotor unmanned aerial vehicle (UAV) was verified by the Ironbird ground test, which considerably reduces cost and risk during the developmental stages. The function and performance of the engine, drive line, nacelle conversion, and rotor systems were evaluated using a building block test approach. The Ironbird test concept facilitates the discovery of potential faults in earlier stages of the testing period. As a result, the developmental testing period could effectively be shortened. The measured test data acquired through a ground control and data acquisition system exhibited satisfactory results which meet the developmental specifications of a tilt rotor UAV.

• Journal of Ginseng Research
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• 제48권3호
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• pp.333-340
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• 2024

Background: Korean red ginseng (KRG) is a product from ginseng roots, which is enriched with ginsenosides and has been utilized for a long time as an adaptogen to alleviate various physiological or disease conditions. While KRG is generally considered safe, conducting a thorough toxicological assessment of the spray-dried powder G1899 during the juvenile period is essential to establish its safety profile. This study aimed to assess the safety of G1899 during the juvenile period using Sprague-Dawley rats. Methods: Two studies were conducted separately: a juvenile toxicity study and a uterotrophic bioassay. To assess the potential toxicity at systemic, postnatal developmental, and reproductive levels, G1899 was orally gavaged once a day in post-weaning juvenile Sprague-Dawley (SD) rats at 0, 1250, 2500, or 5000 mg/kg/day. Estrogenicity was assessed by orally gavaging G1899 in immature female SD rats at 0, 2500, or 5000 mg/kg/day on postnatal days (PND) 19-21, followed by a uterotrophic bioassay. These studies were conducted in accordance with the Good Laboratory Practice (GLP) regulations and regulatory test guidelines. Results: Regarding juvenile toxicity, no abnormalities related to the G1899 treatment were observed in any group during the experiment. Moreover, no uterotrophic responses were observed in the dosed female group. Based on these results, the no observed adverse effect level (NOAEL) of G1899 was determined to be at least 5000 mg/kg/day for general systemic function, developmental/reproductive function, and estrogenic activity. Conclusion: Our results suggest that G1899 is not toxic to juveniles at doses of up to 5000 mg/kg/day.