Journal of the Korean Association of Oral and Maxillofacial Surgeons

The Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회)
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MORPHOLOGICAL ANALYSIS OF DEVELOPMENTAL CHANGES IN SOMA AREA OF DIGASTRIC MOTONEURONS IN THE RAT TRIGEMINAL MOTOR NUCLEI

흰쥐의 두힘살근 운동신경세포의 발달과정에 관한 형태학적 분석

  • Kim, Jae-Hyun (Department of Oral & Maxillofacial Surgery, Daegu Fatima Hospital) ;
  • Park, Mi-Hwa (Department of Oral & Maxillofacial Surgery, Daegu Fatima Hospital) ;
  • Paik, Sang-Kyoo (Department of Oral Anatomy and Neurobiology, School of Dentistry, Kyungpook National University) ;
  • Ma, Su-Kyung (Department of Oral Anatomy and Neurobiology, School of Dentistry, Kyungpook National University) ;
  • Baek, Sang-Heum (Department of Oral & Maxillofacial Surgery, Daegu Fatima Hospital) ;
  • Cha, Du-Won (Department of Oral & Maxillofacial Surgery, Daegu Fatima Hospital)
  • 김재현 (대구파티마병원 구강악안면외과) ;
  • 박미화 (대구파티마병원 구강악안면외과) ;
  • 백상규 (경북대학교 치과대학 구강해부학교실) ;
  • 마수경 (경북대학교 치과대학 구강해부학교실) ;
  • 백상흠 (대구파티마병원 구강악안면외과) ;
  • 차두원 (대구파티마병원 구강악안면외과)
  • Published : 2005.04.30
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Abstract

To analyze the developmental changes in soma diameters of digastric motoneurons, wheat-germ agglutinin conjugated horseradish peroxidase (WGA-HRP) was injected into the digastric muscle and visualized the retrogradely HRP-labeled motoneurons through tungstate/tetramethylbenzidine (TMB) and following diaminobenzidine (DAB) reactions. The results obtained from Sprague-Dawley rats at postnatal days 1 (P1), 10 (P10) and 30 (P30) indicated as follows: firstly, soma diameters of digastric motoneurons showed unimodal distribution in all postnatal days examined; secondly, the period of P1 to P10 (period 1) showed about 2 times faster growth rate than that of P10 to P30 (period 2); thirdly, the smallest soma examined in each postnatal day exhibited slower growth rate with that of the largest one (increase ratio in soma diameters from P1 to P30, smallest vs. largest = 1.62 : 1.93); Finally, relative growth rates a day showed again that period 1 had faster growth rate than that of period 2. Consequently, developmental changes in soma diameters of digastric motoneurons resulted in very different growth rates between both periods. This implies that the growth of the soma is almost completing within P10 and thereafter growing slowly. The period 1 and 2 are corresponding to sucking and sucking/masticatory period, respectively. Therefore present study providing morphological changes in soma diameters of digastric motoneurons suggests that both periods and their different growth rates of the motoneurons in each period may closely be related with each other.

Keywords

References

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