• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.17 no.2
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• pp.79-90
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• 2006

Social deficits are the most critical and core deficits of the children with Autistic Spectrum Disorder(ASD) and they are qualitatively as well as qualitatively different from typically developing children. It is proposed that the attachment between the mother and the autistic child should be promoted foremost and early as possible, to improve social deficits, just like early social developments in normal children depend largely on interactions between the mother and the child who are attached to each other we have developed an interventional program, 'Attachment Promotion Therapy', largely based on the attachment theory. The Attachment promotion Therapy mandates the participation of both the mother and the autistic child, and consists of mutually enjoying play activities, close physical contacts and parental training on intense mother-child interactions, focusing on improving maternal sensitivity, responsiveness, and nurturing behaviors during their interactions. The program was found to be effective in improving attachment behaviors, attachment security and acquiring joint attention skills. Attachment Promotion Therapy is therefore proposed here as the important earliest intervention method for children with ASD and could become the base for many other educational and therapeutic interventions.

• Journal of the Korean Society of Costume
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• v.59 no.5
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• pp.71-82
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• 2009

The purpose of this study is to help understanding of patterns and to play a guideline's role in the development of designs and the prediction of trends for present and future fashion designers and textile designers. The methods of this study are the study of academic literatures as well as practical study through the analysis about actual works. The results of study are like followings. An inquiry of Pattern history in 20c is divided into six periods by the classification of styles and the styles of fashion culture according to other artistic formative will. Main trends of Pattern's image in each period and characteristics in each dimensions of Pattern image positioning are like followings. Art Nouveau style period from 1900 to 1910 is , Art Deco style period from 1910 to 1920 is , Elegance style period of 1930s is , and New Romantic style period from 1945 to mid 1950s and Pop style period from late 1950s to mid 1970s does not show main Pattern image but they are shown in four Pattern image of , , , . Compromising style period from late 1980s to 1990s shows all of four Pattern image, at the same time shows intensive main Pattern's image, .

• Korean Journal of Biological Psychiatry
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• v.22 no.3
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• pp.101-108
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• 2015

Recent breakthroughs in functional neuroimaging techniques have launched the quest of mapping the connections of the human brain, otherwise known as the human connectome. Imaging connectomics is an umbrella term that refers to the neuroimaging techniques used to generate these maps, which recently has enabled comprehensive brain mapping of network connectivity combined with graph theoretic methods. In this review, we present an overview of the key concepts in functional connectomics. Furthermore, we discuss articles that applied task-based and/or resting-state functional magnetic resonance imaging to examine network deficits in post-traumatic stress disorder (PTSD). These studies have provided important insights regarding the etiology of PTSD, as well as the overall organization of the brain network. Advances in functional connectomics are expected to provide insight into the pathophysiology and the development of biomarkers for diagnosis and treatment of PTSD.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.31 no.2
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• pp.80-87
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• 2020

Objectives: The prevalence of psychiatric disorders among young adults is different from that among younger or older age groups because of biological and environmental changes. The purpose of this study was to analyze the diagnostic distribution of psychiatric disorders in 19-30-year-old Koreans based on their age and gender using data from the Korean National Health Insurance Service (NHIS). Methods: From the 2011 medical claims sample data of NHIS of 1,375,842 people, we extracted the data of 221,038 people aged 19-30 years, including 106,232 (48.1%) men and 114,806 (51.9%) women. We evaluated the overall changes in the diagnostic distribution of psychiatric disorders over a 3-year period. Results: The diagnostic frequency in women was 13,627 (59.0%), which was significantly higher than that in men. "Other anxiety disorders" was the most common psychiatric disorder in both genders, followed by depressive episodes, somatoform disorders, "other neurotic disorders," and nonorganic sleep disorders. In men, attention-deficit/hyperactivity disorder or intellectual disabilities were not among the top 10 disorders. In women, no significant changes in major psychiatric disorders were seen over the 3-year period. Conclusion: These results reveal the trends of diagnostic distribution of mental illnesses depending on the development, particularly in young adulthood. It is necessary to identify whether such trends are due to biological or environmental factors, aging processes, or complex influences.

• Journal of muscle and joint health
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• v.22 no.1
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• pp.20-29
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• 2015

Purpose: The study was undertaken to investigate effects of susceptibility to musculoskeletal disorder, social support, and environmental aids on exercise adherence intention and to identify factors contributing to exercise adherence intention among university students. Methods: The study was a descriptive study with 277 students from 3 universities. Data were collected from March 5 to May 30, 2014 using a structured self-report questionnaire. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, Pearson correlation coefficients, and Hierarchical multiple regression. Results: The explanatory power of the predictive model involving the demographic factors, susceptibility to musculoskeletal disorder, social support, and environmental aids was 29%, and the subjects' gender, health concern, experience of musculoskeletal injury, regular exercise, and social support were identified as main factors having influence. Conclusion: The results of this study will be helpful in understanding the importance of environmental factors for increasing physical activities and will be used as basic data for development of exercise programs to increase exercise adherence intention for their continuous exercise.

• Journal of Oriental Neuropsychiatry
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• v.24 no.spc1
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• pp.15-22
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• 2013

Objectives : The Hwabyung Research Center of The Korean Society Of Oriental Neuropsychiatry attempted to produce clinical guidelines for doctors of Korean medicine for the treatment of Hwabyung. Methods : A standard guideline development process was followed. Relevant literature was identified by a review of bibliographies. The operational criteria were used to rate the quality of scientific evidence, and the line of treatment recommendations included a consensus clinical opinion. This section of "the status of Hwabyung in Korea" is 2 out of 5 articles drafted and reviewed by clinicians. Results : Hwabyung is changed depending on the time and have a risk of relapse. Like the previous studies, Female and lower socio-economic and educational level people suffers Hwabyung frequently. But recently number of Male Hwabyung patients increases. Recovery of Hwabyung is involved in depression, anxiety, stress. Hwabyung is related to Major depressive disorder, generalized anxiety disorder, somatoform disorder and diseases of the digestive system. Conclusions : This study was observed for the progression of Hwabyung. Hwabyung is a long-term disease associated with depression, anxiety and stress. Hwabyung is accompanied by physical and psychological symptoms and degrades the quality of life.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7393-7400
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• 2015

Matrix metalloproteinase (MMP) 9, a key member of multifunctional family of zinc dependent endopeptidases has been found to be upregulated during inflammation and in some cancers. MMPs cleave extracellular matrix (ECM) proteins and play critical roles in cellular apoptosis, angiogenesis, tumor growth and metastasis. Several genetic polymorphisms have been identified that show allele specific effects on MMP9 regulation and are associated with gastric cancer, the fourth most common malignancy in the world. Besides Helicobacter pylori infection, genetic predisposition is another documented risk factor for gastric carcinoma. The single nucleotide polymorphism (SNP) at position -1562C/T of MMP9 results in the modulation for binding of transcription factors to the MMP9 gene promoter and thereby causes differences in protein expression and enzymatic activity. MMP9 transcriptional regulation during gastric cancer development remains poorly known although several studies have demonstrated associations between MMP9 -1562 C/T polymorphism with different diseases. Knowledge on mechanisms of MMP9 upregulation during gastric cancer may provide new paradigm in diagnostics and therapeutics.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.23 no.1
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• pp.31-35
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• 2012

Noonan syndrome is characterized by short stature, typical facial dysmorphology, and congenital heart defects. The main facial features of Noonan syndrome are hypertelorism with down-slanting palpebral fissures, ptosis, and low-set posteriorly-rotated ears with a thickened helix. The cardiovascular defects most commonly associated with this condition are pulmonary stenosis and hypertrophic cardiomyopathy. Other associated features are webbed neck, chest deformity, mild intellectual deficit, cryptorchidism, poor feeding in infancy, bleeding tendency, and lymphatic dysplasias. The patient is a 10-year-old boy. He had experienced repeated febrile convulsions. He had typical facial features, a short stature, chest deformity, cryptorchidism, vesicoureteral reflux, and mental retardation. His language and motor development were delayed. When he went to school, it was difficult for him to pay attention, follow directions, and organize tasks. He also displayed behavior such as squirming, leaving his seat in class, and running around inappropriately. Clinical observation is important for the diagnosis, so we report a patient who was diagnosed with Noonan syndrome, mental retardation, and attention-deficit hyperactivity disorder.

• Phonetics and Speech Sciences
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• v.8 no.2
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• pp.65-71
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• 2016

The purpose of this study is to examine the prosodic pattern of the children with high functioning autism spectrum disorder(HFASD) according to sentence type. The participants were 18 children aged from 7 - 9 years; 9 children with HFASD and 9 typical development children(TD) of the same chronological age with HFASD children. Sentence reading tasks were conducted in this study. Seven interrogative sentences and 7 declarative sentences were presented to the participants and were asked to read the sentences three times. Mean values of F0, F0 range, intensity, speech rate and pitch contour were measured for each sentence. The results showed that for F0 range, significant main effect and interaction effect were observed in the subject group and sentence type. There were significant differences in intensity, mean F0, speech rate, pitch contour across sentence types. The results of this study indicated that HFASD showed no difference in intonation across sentence types. Speakers' intention may have a negative effect on pragmatic aspects. These results suggest that the assessment and intervention of prosody be important for HFASD.

• Anxiety and mood
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• v.8 no.1
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• pp.3-8
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• 2012

Patients with panic disoder (PD) show recollection of their first panic attack, which resembles a trauma that is perceived as an unexpected frightening and subjectively life-threatening event. Information-processing models suggest that anxiety disorders may be characterized by a memory bias for threat-related information. This paper reviews the previous researches that investigated the implicit and/or explicit biases in patients with panic disorder. Among the 17 studies, which addressed the explicit memory bias in PD patients, 11 (64.7%) were found to be explicit memory bias in PD patients. In regards to the implicit memory bias, 4 out of 9 studies (44.4%) were found to support the memory bias. The result shows that evidence of explicit memory bias in PD patients was supported by a number of previous researches. However, evidence of implicit memory bias seems less robust, thus, needs further research for replication. Also, development of new paradigms and applications of various methods will be needed in further researches on memory bias in PD patients.