Korean Journal of Biological Psychiatry (생물정신의학)

The Korean Society of Biological Psychiatry (대한생물정신의학회)
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Advances in Functional Connectomics in Neuroscience : A Focus on Post-Traumatic Stress Disorder

뇌과학 분야 기능적 연결체학의 발전 : 외상후스트레스장애를 중심으로

  • Park, Shinwon (Department of Psychology, Ewha Womans University) ;
  • Jeong, Hyeonseok S. (Department of Radiology, Incheon St. Mary's Hospital, The Catholic University of Korea) ;
  • Lyoo, In Kyoon (Department of Brain and Cognitive Sciences and Ewha Brain Institute, Ewha Womans University)
  • 박신원 (이화여자대학교 심리학과) ;
  • 정현석 (가톨릭대학교 인천성모병원 영상의학과) ;
  • 류인균 (이화여자대학교 뇌.인지과학과, 뇌융합과학연구원)
  • Received : 2015.06.16
  • Accepted : 2015.06.26
  • Published : 2015.08.31
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Abstract

Recent breakthroughs in functional neuroimaging techniques have launched the quest of mapping the connections of the human brain, otherwise known as the human connectome. Imaging connectomics is an umbrella term that refers to the neuroimaging techniques used to generate these maps, which recently has enabled comprehensive brain mapping of network connectivity combined with graph theoretic methods. In this review, we present an overview of the key concepts in functional connectomics. Furthermore, we discuss articles that applied task-based and/or resting-state functional magnetic resonance imaging to examine network deficits in post-traumatic stress disorder (PTSD). These studies have provided important insights regarding the etiology of PTSD, as well as the overall organization of the brain network. Advances in functional connectomics are expected to provide insight into the pathophysiology and the development of biomarkers for diagnosis and treatment of PTSD.

Keywords

References

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